JPS57139066A - Isoquinoline derivative and its preparation - Google Patents
Isoquinoline derivative and its preparationInfo
- Publication number
- JPS57139066A JPS57139066A JP2481281A JP2481281A JPS57139066A JP S57139066 A JPS57139066 A JP S57139066A JP 2481281 A JP2481281 A JP 2481281A JP 2481281 A JP2481281 A JP 2481281A JP S57139066 A JPS57139066 A JP S57139066A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formulai
- hydroxy
- bond
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An isoquinoline derivative shown by the formulaI(R1 and R2 are H, OH, acyloxy, alkoxy; R3 and R4 are H, or form a bond; R5 is H, acyl, R6 is H, or R5 and R6 form a bond; R7 is alkylene; R8 is H, alkyl; R9 is nitrogen- containing five-membered aromatic heterocyclic group substituted by alkyl; when R1 is 6-hydroxy, R2 is 7-hydroxy, and R3WR6 are H, R8 is alkyl).
EXAMPLE: 6,7-Dihydroxy-1-[N-methyl-N-( 1-methyl-1H-tetrazole-5-yl- )aminomethyl]-1,2,3,4-tetrahydroisoquinoline.
USE: A drug having a suppressing action on the secretion of gastric juice.
PROCESS: For example, a phenethylamine derivative shown by the formula II or its salt is reacted with a compound shown by the formula III or its reactive equivalent or their salts, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2481281A JPS57139066A (en) | 1981-02-20 | 1981-02-20 | Isoquinoline derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2481281A JPS57139066A (en) | 1981-02-20 | 1981-02-20 | Isoquinoline derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57139066A true JPS57139066A (en) | 1982-08-27 |
Family
ID=12148597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2481281A Pending JPS57139066A (en) | 1981-02-20 | 1981-02-20 | Isoquinoline derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57139066A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0404197A2 (en) * | 1989-06-23 | 1990-12-27 | Kyowa Hakko Kogyo Co., Ltd. | Arylalkylamine derivatives |
US7504393B2 (en) | 2001-01-26 | 2009-03-17 | Btg International Limited | Benzylamine analogues |
-
1981
- 1981-02-20 JP JP2481281A patent/JPS57139066A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0404197A2 (en) * | 1989-06-23 | 1990-12-27 | Kyowa Hakko Kogyo Co., Ltd. | Arylalkylamine derivatives |
US7504393B2 (en) | 2001-01-26 | 2009-03-17 | Btg International Limited | Benzylamine analogues |
US7504437B2 (en) | 2001-01-26 | 2009-03-17 | Btg International Limited | Benzylamine analogues |
US7514475B2 (en) | 2001-01-26 | 2009-04-07 | Btg International Limited | Benzylamine analogues |
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