DK1217001T3 - Quinuclidinforbindelser og lægemidler indeholdende dem som den aktive bestanddel - Google Patents

Quinuclidinforbindelser og lægemidler indeholdende dem som den aktive bestanddel

Info

Publication number
DK1217001T3
DK1217001T3 DK00962889T DK00962889T DK1217001T3 DK 1217001 T3 DK1217001 T3 DK 1217001T3 DK 00962889 T DK00962889 T DK 00962889T DK 00962889 T DK00962889 T DK 00962889T DK 1217001 T3 DK1217001 T3 DK 1217001T3
Authority
DK
Denmark
Prior art keywords
optionally substituted
chain
substituted
denotes
represented
Prior art date
Application number
DK00962889T
Other languages
English (en)
Inventor
Toshimi Okada
Nobuyuki Kurusu
Daisuke Shinmyo
Hironori Ikuta
Mamoru Yanagimachi
Keigo Tanaka
Kazuki Miyazaki
Hiroyuki Sugumi
Hironobu Ruminasu Kann Hiyoshi
Takao Saeki
Masashi Ito
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of DK1217001T3 publication Critical patent/DK1217001T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK00962889T 1999-09-28 2000-09-27 Quinuclidinforbindelser og lægemidler indeholdende dem som den aktive bestanddel DK1217001T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27390599 1999-09-28
JP2000179352 2000-06-15

Publications (1)

Publication Number Publication Date
DK1217001T3 true DK1217001T3 (da) 2006-03-20

Family

ID=26550809

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00962889T DK1217001T3 (da) 1999-09-28 2000-09-27 Quinuclidinforbindelser og lægemidler indeholdende dem som den aktive bestanddel

Country Status (20)

Country Link
US (1) US6599917B1 (da)
EP (1) EP1217001B1 (da)
JP (1) JP4206212B2 (da)
KR (1) KR100694687B1 (da)
CN (1) CN100334085C (da)
AT (1) ATE312100T1 (da)
AU (1) AU782114B2 (da)
BR (1) BR0014331A (da)
CA (1) CA2385995C (da)
DE (1) DE60024651T2 (da)
DK (1) DK1217001T3 (da)
ES (1) ES2252063T3 (da)
HU (1) HUP0203514A3 (da)
IL (2) IL148631A0 (da)
MX (1) MXPA02003167A (da)
NO (1) NO328218B1 (da)
NZ (1) NZ517788A (da)
RU (1) RU2266905C2 (da)
TW (1) TWI282794B (da)
WO (1) WO2001023383A1 (da)

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DE10225537A1 (de) * 2002-06-10 2003-12-18 Bayer Ag N-alkylierte Thiazoliumsalze und Verfahren zu deren Herstellung
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CA2560741C (en) 2004-03-25 2013-08-06 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
US8106066B2 (en) 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
EP2132196A1 (en) 2007-02-26 2009-12-16 Pfizer Products Inc. Nicotinamide derivatives as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases
TW201111385A (en) 2009-08-27 2011-04-01 Biocryst Pharm Inc Heterocyclic compounds as janus kinase inhibitors
US8420661B2 (en) * 2010-04-13 2013-04-16 Hoffmann-La Roche Inc. Arylethynyl derivatives
WO2011150356A1 (en) 2010-05-28 2011-12-01 Biocryst Pharmaceuticals, Inc. Heterocyclic compounds as janus kinase inhibitors
WO2013102145A1 (en) 2011-12-28 2013-07-04 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
ES2963218T3 (es) 2011-12-28 2024-03-25 Global Blood Therapeutics Inc Productos intermedios para obtener compuestos de benzaldehído sustituidos y métodos para su uso en el aumento de la oxigenación tisular
WO2014060381A1 (de) 2012-10-18 2014-04-24 Bayer Cropscience Ag Heterocyclische verbindungen als schädlingsbekämpfungsmittel
BR112015009751A2 (pt) 2012-10-31 2017-07-11 Bayer Cropscience Ag novos compostos heterocíclicos como pesticidas
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20160083343A1 (en) 2013-03-15 2016-03-24 Global Blood Therapeutics, Inc Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
CN111454200A (zh) 2013-03-15 2020-07-28 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
CA2902711C (en) 2013-03-15 2021-07-06 Global Blood Therapeutics, Inc. Substituted pyridinyl-6-methoxy-2-hydroxybenzaldehyde derivatives and pharmaceutical compositions thereof useful for the modulation of hemoglobin
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
CA2916564C (en) 2014-02-07 2023-02-28 Global Blood Therapeutics, Inc. Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
CR20170536A (es) 2015-06-03 2018-02-01 Hoffmann La Roche Derivados de etinilo
SG10201912511WA (en) 2015-12-04 2020-02-27 Global Blood Therapeutics Inc Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
TWI663160B (zh) 2016-05-12 2019-06-21 全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
TWI778983B (zh) 2016-10-12 2022-10-01 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
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Also Published As

Publication number Publication date
NO20021528D0 (no) 2002-03-26
TWI282794B (en) 2007-06-21
NO20021528L (no) 2002-05-28
HUP0203514A3 (en) 2004-01-28
EP1217001A4 (en) 2002-12-18
WO2001023383A1 (fr) 2001-04-05
ES2252063T3 (es) 2006-05-16
RU2266905C2 (ru) 2005-12-27
NO328218B1 (no) 2010-01-11
CN1377349A (zh) 2002-10-30
ATE312100T1 (de) 2005-12-15
HUP0203514A2 (hu) 2003-03-28
CN100334085C (zh) 2007-08-29
IL148631A0 (en) 2002-09-12
EP1217001B1 (en) 2005-12-07
CA2385995A1 (en) 2001-04-05
CA2385995C (en) 2009-06-16
EP1217001A1 (en) 2002-06-26
DE60024651T2 (de) 2006-09-28
MXPA02003167A (es) 2003-10-06
JP4206212B2 (ja) 2009-01-07
KR20020034197A (ko) 2002-05-08
DE60024651D1 (de) 2006-01-12
US6599917B1 (en) 2003-07-29
IL148631A (en) 2010-04-29
KR100694687B1 (ko) 2007-03-13
AU782114B2 (en) 2005-07-07
AU7446400A (en) 2001-04-30
BR0014331A (pt) 2003-06-10
NZ517788A (en) 2003-11-28

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