DK1161530T3 - Protein til blokering af blodpladeadhæsion - Google Patents

Protein til blokering af blodpladeadhæsion

Info

Publication number
DK1161530T3
DK1161530T3 DK00909351T DK00909351T DK1161530T3 DK 1161530 T3 DK1161530 T3 DK 1161530T3 DK 00909351 T DK00909351 T DK 00909351T DK 00909351 T DK00909351 T DK 00909351T DK 1161530 T3 DK1161530 T3 DK 1161530T3
Authority
DK
Denmark
Prior art keywords
protein
platelet adhesion
block platelet
block
adhesion
Prior art date
Application number
DK00909351T
Other languages
Danish (da)
English (en)
Inventor
Wolfgang Strittmatter
Juergen Hemberger
Bernhard Scheuble
Detlef Guessow
Uwe Hofmann
Zisi Fotev
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of DK1161530T3 publication Critical patent/DK1161530T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK00909351T 1999-03-18 2000-03-10 Protein til blokering af blodpladeadhæsion DK1161530T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP99105530 1999-03-18
EP99109503 1999-05-12
EP00909351A EP1161530B1 (en) 1999-03-18 2000-03-10 Protein for blocking platelet adhesion
PCT/EP2000/002117 WO2000056885A1 (en) 1999-03-18 2000-03-10 Protein for blocking platelet adhesion

Publications (1)

Publication Number Publication Date
DK1161530T3 true DK1161530T3 (da) 2005-08-08

Family

ID=26152935

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00909351T DK1161530T3 (da) 1999-03-18 2000-03-10 Protein til blokering af blodpladeadhæsion

Country Status (27)

Country Link
US (3) US6774107B1 (zh)
EP (1) EP1161530B1 (zh)
JP (1) JP4805461B2 (zh)
KR (1) KR100788219B1 (zh)
CN (1) CN1185344C (zh)
AR (1) AR023099A1 (zh)
AT (1) ATE295883T1 (zh)
AU (1) AU767172B2 (zh)
BR (1) BR0009074A (zh)
CA (1) CA2367457C (zh)
CO (1) CO5241328A1 (zh)
CZ (1) CZ301524B6 (zh)
DE (1) DE60020220T2 (zh)
DK (1) DK1161530T3 (zh)
ES (1) ES2240067T3 (zh)
HK (1) HK1045330B (zh)
HU (1) HU228068B1 (zh)
MX (1) MXPA01009363A (zh)
MY (1) MY123371A (zh)
NO (1) NO330769B1 (zh)
PL (1) PL200384B1 (zh)
PT (1) PT1161530E (zh)
RU (1) RU2292351C2 (zh)
SI (1) SI1161530T1 (zh)
SK (1) SK287496B6 (zh)
TR (1) TR200102729T2 (zh)
WO (1) WO2000056885A1 (zh)

Families Citing this family (33)

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US6774107B1 (en) 1999-03-18 2004-08-10 Merck Patent Gmbh Protein for blocking platelet adhesion
MY128992A (en) 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
JP2005511005A (ja) * 2001-07-18 2005-04-28 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング 糖タンパク質ｖｉ融合タンパク質
WO2005042043A2 (en) 2003-10-28 2005-05-12 Medtronic, Inc. Methods of preparing crosslinked materials and bioprosthetic devices
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
WO2006044290A2 (en) * 2004-10-12 2006-04-27 Board Of Trustees Of Michigan State University Biosynthesis of philoroglucinol and preparation of 1,3-dihydroxybenzene therefrom
CA2611102A1 (en) * 2005-05-26 2006-11-30 Thomas Jefferson University Method to treat and prevent posterior capsule opacification
US7691839B2 (en) * 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
US20080015145A1 (en) 2006-07-11 2008-01-17 Maria Gyongyossy-Issa Mimotope receptors and inhibitors for platelet-platelet and platelet-endothelium interactions
GB2460915B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor
EP3335715A3 (en) 2008-10-15 2018-08-08 Ionis Pharmaceuticals, Inc. Modulation of factor 11 expression
WO2012003461A2 (en) 2010-07-02 2012-01-05 Draths Corporation Phloroglucinol synthases and methods of making and using the same
WO2012006245A1 (en) 2010-07-06 2012-01-12 Draths Corporation Phloroglucinol reductase and methods of making and using the same
WO2012006244A1 (en) 2010-07-06 2012-01-12 Draths Corporation Method for producing phloroglucinol and dihydrophloroglucinol
RS63063B1 (sr) 2010-08-19 2022-04-29 Zoetis Belgium S A Anti-ngf antitela i njihova upotreba
US8790651B2 (en) 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
DE202012012998U1 (de) 2011-08-31 2014-06-13 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
WO2013184871A1 (en) 2012-06-06 2013-12-12 Zoetis Llc Caninized anti-ngf antibodies and methods thereof
MX2015000789A (es) 2012-07-19 2015-05-07 Zoetis Llc Composiciones de virus de la gripe bovina.
AU2013295770A1 (en) 2012-07-27 2015-01-29 Zoetis Services Llc Tick toxin compositions
EP3500292B1 (en) 2016-08-17 2024-10-16 Pharmaq AS Sea lice vaccine
BR102017005783A2 (pt) * 2017-03-21 2018-10-02 Fund Butantan processo de obtenção de esculptina e seus fragmentos, esculptina recombinante e seus usos
WO2019177690A1 (en) 2018-03-12 2019-09-19 Zoetis Services Llc Anti-ngf antibodies and methods thereof
BR112020017715A2 (pt) 2018-03-16 2020-12-29 Zoetis Services Llc Vacinas de peptídeo contra interleucina-31
EP3765500A2 (en) 2018-03-16 2021-01-20 Zoetis Services LLC Interleukin-31 monoclonal antibodies for veterinary use
JOP20200280A1 (ar) 2018-05-09 2020-11-05 Ionis Pharmaceuticals Inc مركبات وطرق لتقليل التعبير الوراثي عن fxi
US11464849B2 (en) 2019-09-11 2022-10-11 Zoetis Services Llc Recombinant herpesvirus of turkey vectors expressing antigens of avian pathogens and uses thereof
US20220119513A1 (en) 2020-06-08 2022-04-21 Zoetis Services Llc Anti-tgfb antibodies and therapeutic uses thereof
US20210386854A1 (en) 2020-06-15 2021-12-16 Zoetis Services Llc Cell Line for Production of Marek's Disease Virus Vaccine and Methods of Making and Using the Same
MX2023004020A (es) 2020-10-07 2023-07-07 Zoetis Services Llc Anticuerpos anti-ngf y métodos para su uso.
TW202221039A (zh) 2020-10-19 2022-06-01 美商碩騰服務公司 犬及貓抑瘤素Ｍ受體β之抗體及其用途
WO2023049917A1 (en) 2021-09-27 2023-03-30 Zoetis Services Llc ANTI- TGFβ1,2,3 ANTIBODIES AND THERAPEUTIC USES THEREOF

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705355A (en) * 1984-03-27 1998-01-06 Transgene, S.A. Hirudin, pharmaceutical compositions comprising it and their use
US4898734A (en) 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
IL86857A (en) * 1988-06-24 1994-04-12 Yissum Res Dev Co Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same
US5182260A (en) * 1989-01-27 1993-01-26 Biogen, Inc. Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation
GB9022040D0 (en) * 1990-10-10 1990-11-21 Biopharm Ltd Platelet adhesion inhibitor
DE4136513A1 (de) * 1991-11-06 1993-05-13 Basf Ag Neues thrombininhibitorisches protein aus raubwanzen
JP3742429B2 (ja) * 1993-07-01 2006-02-01 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング コラーゲン刺激血小板凝集の阻害剤
EP1118325B2 (en) 1993-07-29 2010-01-06 The United States of America, represented by the Secretary, Department of Health and Human Services Use of Paclitaxel and its derivatives in the manufacture of a medicament for treating restenosis.
CZ76297A3 (cs) * 1994-09-12 1998-01-14 Schering Aktiengesellschaft Způsob výroby modifikovaného pallidipinu - inhibitoru agregace krevních destiček vyvolané kolagenem
ATE211765T1 (de) * 1994-10-28 2002-01-15 Vitaleech Bioscience N V Neue familie von proteaseinhibitoren und andere biologisch aktive substanzen
US6774107B1 (en) * 1999-03-18 2004-08-10 Merck Patent Gmbh Protein for blocking platelet adhesion
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen

Also Published As

Publication number Publication date
CZ301524B6 (cs) 2010-03-31
CA2367457A1 (en) 2000-09-28
AU3166200A (en) 2000-10-09
CZ20013341A3 (cs) 2002-01-16
SK287496B6 (sk) 2010-12-07
MXPA01009363A (es) 2002-06-04
NO20014506L (no) 2001-11-16
ES2240067T3 (es) 2005-10-16
EP1161530B1 (en) 2005-05-18
US20060094079A1 (en) 2006-05-04
CN1185344C (zh) 2005-01-19
PL350147A1 (en) 2002-11-04
EP1161530A1 (en) 2001-12-12
SK12902001A3 (sk) 2002-03-05
KR100788219B1 (ko) 2007-12-26
CO5241328A1 (es) 2003-01-31
US6774107B1 (en) 2004-08-10
DE60020220D1 (de) 2005-06-23
ATE295883T1 (de) 2005-06-15
DE60020220T2 (de) 2006-05-24
RU2292351C2 (ru) 2007-01-27
US7090986B2 (en) 2006-08-15
HK1045330B (zh) 2005-09-09
AR023099A1 (es) 2002-09-04
SI1161530T1 (en) 2005-10-31
KR20020008131A (ko) 2002-01-29
TR200102729T2 (tr) 2002-04-22
AU767172B2 (en) 2003-11-06
PL200384B1 (pl) 2008-12-31
CA2367457C (en) 2010-09-21
WO2000056885A1 (en) 2000-09-28
JP2002539788A (ja) 2002-11-26
HUP0200353A3 (en) 2003-12-29
NO330769B1 (no) 2011-07-11
JP4805461B2 (ja) 2011-11-02
CN1344318A (zh) 2002-04-10
BR0009074A (pt) 2002-01-02
US20050065084A1 (en) 2005-03-24
NO20014506D0 (no) 2001-09-17
HUP0200353A2 (hu) 2002-05-29
HK1045330A1 (en) 2002-11-22
US6962801B2 (en) 2005-11-08
PT1161530E (pt) 2005-09-30
MY123371A (en) 2006-05-31
HU228068B1 (en) 2012-09-28

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