US5780A
(en)
|
|
1848-09-19 |
|
Improvement in preparing shoe-pegs |
US4526A
(en)
|
|
1846-05-16 |
|
Improvement in the mode o |
US498A
(en)
|
|
1837-12-01 |
|
Improvement in mode of constructing saw-cylinders for cotton-gins |
US938A
(en)
|
|
1838-09-22 |
|
Improvement in paddle-wheels for propelling boats |
US225A
(en)
|
|
1837-06-03 |
|
Machine fob |
US5258A
(en)
|
|
1847-08-28 |
|
Cooking-stove |
US4230691A
(en)
|
1978-05-23 |
1980-10-28 |
The Massachusetts General Hospital |
Nerve growth factor antibody and process
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
DE3378250D1
(en)
|
1982-04-22 |
1988-11-24 |
Ici Plc |
Continuous release formulations
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
US5128326A
(en)
|
1984-12-06 |
1992-07-07 |
Biomatrix, Inc. |
Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
|
US6492107B1
(en)
|
1986-11-20 |
2002-12-10 |
Stuart Kauffman |
Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
|
DE229046T1
(de)
|
1985-03-30 |
1987-12-17 |
Marc Genf/Geneve Ballivet |
Verfahren zum erhalten von dns, rns, peptiden, polypeptiden oder proteinen durch dns-rekombinant-verfahren.
|
US4980286A
(en)
|
1985-07-05 |
1990-12-25 |
Whitehead Institute For Biomedical Research |
In vivo introduction and expression of foreign genetic material in epithelial cells
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
DE3600905A1
(de)
|
1986-01-15 |
1987-07-16 |
Ant Nachrichtentech |
Verfahren zum dekodieren von binaersignalen sowie viterbi-dekoder und anwendungen
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
DE3883899T3
(de)
|
1987-03-18 |
1999-04-22 |
Sb2, Inc., Danville, Calif. |
Geänderte antikörper.
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
US4880078A
(en)
|
1987-06-29 |
1989-11-14 |
Honda Giken Kogyo Kabushiki Kaisha |
Exhaust muffler
|
WO1989009225A1
(en)
|
1988-03-28 |
1989-10-05 |
The Regents Of The University Of California |
Nerve growth factor peptides
|
EP0440663A1
(de)
|
1988-08-08 |
1991-08-14 |
IFFIU, Michael A. |
Klappbares sesselrad mit stromlinienförmiger, in drei geteilter und faltbarer verkleidung
|
DE68927933T2
(de)
|
1988-09-02 |
1997-08-14 |
Dyax Corp |
Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
WO1990005144A1
(en)
|
1988-11-11 |
1990-05-17 |
Medical Research Council |
Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
GB8905669D0
(en)
|
1989-03-13 |
1989-04-26 |
Celltech Ltd |
Modified antibodies
|
CA2016841C
(en)
|
1989-05-16 |
1999-09-21 |
William D. Huse |
A method for producing polymers having a preselected activity
|
AU652539B2
(en)
|
1989-05-16 |
1994-09-01 |
Medical Research Council |
Co-expression of heteromeric receptors
|
CA2016842A1
(en)
|
1989-05-16 |
1990-11-16 |
Richard A. Lerner |
Method for tapping the immunological repertoire
|
AU640397B2
(en)
|
1989-08-25 |
1993-08-26 |
Juridical Foundation The Chemo-Sero-Therapeutic Research Institute |
Dog-mouse heterohybridoma and gene fragment coding for constant region of canine immunoglobulin
|
US5656435A
(en)
|
1989-08-28 |
1997-08-12 |
Takeda Chemical Industries, Ltd. |
Antibodies to peptides having NGF-like activity, said antibodies having no substantial cross-reactivity with NGF, and use thereof
|
AU6430190A
(en)
|
1989-10-10 |
1991-05-16 |
Pitman-Moore, Inc. |
Sustained release composition for macromolecular proteins
|
AU642932B2
(en)
|
1989-11-06 |
1993-11-04 |
Alkermes Controlled Therapeutics, Inc. |
Protein microspheres and methods of using them
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
WO1991010737A1
(en)
|
1990-01-11 |
1991-07-25 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
DE69133566T2
(de)
|
1990-01-12 |
2007-12-06 |
Amgen Fremont Inc. |
Bildung von xenogenen Antikörpern
|
US5242937A
(en)
|
1990-03-19 |
1993-09-07 |
Research Corporation Technologies, Inc. |
Topically active ocular thiadiazole sulfonamide carbonic anhydrase inhibitors
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
JPH06508511A
(ja)
|
1990-07-10 |
1994-09-29 |
ケンブリッジ アンティボディー テクノロジー リミティド |
特異的な結合ペアーの構成員の製造方法
|
EP0542810A1
(en)
|
1990-08-02 |
1993-05-26 |
B.R. Centre Limited |
Methods for the production of proteins with a desired function
|
DE69130647T2
(de)
|
1990-08-24 |
1999-05-06 |
Ixsys, Inc., San Diego, Calif. |
Verfahren zur herstellung von oligonukleotiden mit regellosen codonen
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
EP0814159B1
(en)
|
1990-08-29 |
2005-07-27 |
GenPharm International, Inc. |
Transgenic mice capable of producing heterologous antibodies
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
US5147294A
(en)
|
1990-10-01 |
1992-09-15 |
Trustees Of Boston University |
Therapeutic method for reducing chronic pain in a living subject
|
FR2669336B1
(fr)
|
1990-11-20 |
1993-01-22 |
Adir |
Nouveaux derives d'oxazolo pyridines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
|
AU9164991A
(en)
|
1990-11-30 |
1992-06-25 |
Abbott Laboratories |
Immunoassay and monoclonal antibodies useful for detecting truncated nerve growth factor receptor
|
DE69129154T2
(de)
|
1990-12-03 |
1998-08-20 |
Genentech, Inc., South San Francisco, Calif. |
Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
|
WO1992011272A1
(en)
|
1990-12-20 |
1992-07-09 |
Ixsys, Inc. |
Optimization of binding proteins
|
EP0575485A1
(en)
|
1991-03-01 |
1993-12-29 |
Dyax Corp. |
Process for the development of binding mini-proteins
|
JP3672306B2
(ja)
|
1991-04-10 |
2005-07-20 |
ザ スクリップス リサーチ インスティテュート |
ファージミドを使用するヘテロ二量体受容体ライブラリー
|
ES2181673T3
(es)
|
1991-05-01 |
2003-03-01 |
Jackson H M Found Military Med |
Procedimiento de tratamiento de las enfermedades respiratorias infecciosas.
|
US6797492B2
(en)
|
1991-05-17 |
2004-09-28 |
Merck & Co., Inc. |
Method for reducing the immunogenicity of antibody variable domains
|
DE69233482T2
(de)
|
1991-05-17 |
2006-01-12 |
Merck & Co., Inc. |
Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
|
CA2110799A1
(en)
|
1991-06-14 |
1992-12-23 |
Arnold H. Horwitz |
Microbially-produced antibody fragments and their conjugates
|
AU675916B2
(en)
|
1991-06-14 |
1997-02-27 |
Genentech Inc. |
Method for making humanized antibodies
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
DE4122599C2
(de)
|
1991-07-08 |
1993-11-11 |
Deutsches Krebsforsch |
Phagemid zum Screenen von Antikörpern
|
US5350576A
(en)
|
1991-09-13 |
1994-09-27 |
Mycogen Corporation |
Bacillus thuringiensis isolates for controlling acarides
|
CA2078539C
(en)
|
1991-09-18 |
2005-08-02 |
Kenya Shitara |
Process for producing humanized chimera antibody
|
DE69229477T2
(de)
|
1991-09-23 |
1999-12-09 |
Cambridge Antibody Technology Ltd., Melbourn |
Methoden zur Herstellung humanisierter Antikörper
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
ATE408012T1
(de)
|
1991-12-02 |
2008-09-15 |
Medical Res Council |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
DE69233204T2
(de)
|
1991-12-13 |
2004-07-15 |
Xoma Corp., Berkeley |
Verfahren und materialien zur herstellung von modifizierten variablen antikörperdomänen und ihre therapeutische verwendung
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
US5912015A
(en)
|
1992-03-12 |
1999-06-15 |
Alkermes Controlled Therapeutics, Inc. |
Modulated release from biocompatible polymers
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
US5342942A
(en)
|
1992-06-09 |
1994-08-30 |
Warner-Lambert Company |
Pyrazoloquinazolone derivatives as neurotrophic agents
|
EP0652950B1
(en)
|
1992-07-24 |
2007-12-19 |
Amgen Fremont Inc. |
Generation of xenogeneic antibodies
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
US5604260A
(en)
|
1992-12-11 |
1997-02-18 |
Merck Frosst Canada Inc. |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
|
US5934272A
(en)
|
1993-01-29 |
1999-08-10 |
Aradigm Corporation |
Device and method of creating aerosolized mist of respiratory drug
|
AU6132994A
(en)
|
1993-02-02 |
1994-08-29 |
Scripps Research Institute, The |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
US5409944A
(en)
|
1993-03-12 |
1995-04-25 |
Merck Frosst Canada, Inc. |
Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
|
US6180377B1
(en)
|
1993-06-16 |
2001-01-30 |
Celltech Therapeutics Limited |
Humanized antibodies
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
US5436265A
(en)
|
1993-11-12 |
1995-07-25 |
Merck Frosst Canada, Inc. |
1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
|
US5565352A
(en)
|
1993-11-24 |
1996-10-15 |
Arch Development Corporation |
Deubiquitinating enzyme: compositions and methods
|
US5753225A
(en)
|
1993-12-03 |
1998-05-19 |
The Regents Of The University Of California |
Antibodies that mimic actions of neurotrophins
|
WO1995015982A2
(en)
|
1993-12-08 |
1995-06-15 |
Genzyme Corporation |
Process for generating specific antibodies
|
DE69534347T2
(de)
|
1994-01-31 |
2006-05-24 |
Trustees Of Boston University, Boston |
Bibliotheken aus Polyklonalen Antikörpern
|
GB9402331D0
(en)
|
1994-02-07 |
1994-03-30 |
Univ Mcgill |
Nerve growth factor structural analogs and their uses
|
US5844092A
(en)
|
1994-03-18 |
1998-12-01 |
Genentech, Inc. |
Human TRK receptors and neurotrophic factor inhibitors
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
US6291247B1
(en)
|
1994-05-11 |
2001-09-18 |
Queen's University At Kingston |
Methods of screening for factors that disrupt neurotrophin conformation and reduce neurotrophin biological activity
|
US5475995A
(en)
|
1994-05-16 |
1995-12-19 |
Livingston; George G. |
Truck spare tire locking rod
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
GB9514160D0
(en)
|
1994-07-25 |
1995-09-13 |
Zeneca Ltd |
Aromatic compounds
|
US5616601A
(en)
|
1994-07-28 |
1997-04-01 |
Gd Searle & Co |
1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation
|
US5521213A
(en)
|
1994-08-29 |
1996-05-28 |
Merck Frosst Canada, Inc. |
Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
|
US5448082A
(en)
|
1994-09-27 |
1995-09-05 |
Opto Diode Corporation |
Light emitting diode for use as an efficient emitter or detector of light at a common wavelength and method for forming the same
|
US5593994A
(en)
|
1994-09-29 |
1997-01-14 |
The Dupont Merck Pharmaceutical Company |
Prostaglandin synthase inhibitors
|
ATE252894T1
(de)
|
1995-01-05 |
2003-11-15 |
Univ Michigan |
Oberflächen-modifizierte nanopartikel und verfahren für ihre herstellung und verwendung
|
US5552422A
(en)
|
1995-01-11 |
1996-09-03 |
Merck Frosst Canada, Inc. |
Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents
|
US6130364A
(en)
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
US6091001A
(en)
|
1995-03-29 |
2000-07-18 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
US6019968A
(en)
|
1995-04-14 |
2000-02-01 |
Inhale Therapeutic Systems, Inc. |
Dispersible antibody compositions and methods for their preparation and use
|
EP0826034A4
(en)
|
1995-04-21 |
2002-06-19 |
Cell Genesys Inc |
PRODUCTION OF LARGE GENOMIC DNA DELETIONS
|
ATE390933T1
(de)
|
1995-04-27 |
2008-04-15 |
Amgen Fremont Inc |
Aus immunisierten xenomäusen stammende menschliche antikörper gegen il-8
|
AU2466895A
(en)
|
1995-04-28 |
1996-11-18 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5639780A
(en)
|
1995-05-22 |
1997-06-17 |
Merck Frosst Canada, Inc. |
N-benzyl indol-3-yl butanoic acid derivatives as cyclooxygenase inhibitors
|
US5510368A
(en)
|
1995-05-22 |
1996-04-23 |
Merck Frosst Canada, Inc. |
N-benzyl-3-indoleacetic acids as antiinflammatory drugs
|
US5604253A
(en)
|
1995-05-22 |
1997-02-18 |
Merck Frosst Canada, Inc. |
N-benzylindol-3-yl propanoic acid derivatives as cyclooxygenase inhibitors
|
US6265150B1
(en)
|
1995-06-07 |
2001-07-24 |
Becton Dickinson & Company |
Phage antibodies
|
US5693735A
(en)
|
1995-07-12 |
1997-12-02 |
Shin-Etsu Chemical Co., Ltd. |
Trimethylsiloxy group-containing polysiloxane and a process for producing the same
|
US6127977A
(en)
|
1996-11-08 |
2000-10-03 |
Cohen; Nathan |
Microstrip patch antenna with fractal structure
|
JP2000507912A
(ja)
|
1995-08-31 |
2000-06-27 |
アルカームズ コントロールド セラピューティックス,インコーポレイテッド |
作用剤の徐放性組成物
|
WO1997015593A1
(en)
|
1995-10-25 |
1997-05-01 |
Queen's University At Kingston |
Neurotrophin antagonists
|
US6331431B1
(en)
|
1995-11-28 |
2001-12-18 |
Ixsys, Inc. |
Vacuum device and method for isolating periplasmic fraction from cells
|
GB9525180D0
(en)
|
1995-12-08 |
1996-02-07 |
Univ Mcgill |
Design of hormone-like antibodies with agonistic and antagonistic fuctions
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
BRPI9715219B8
(pt)
|
1996-02-09 |
2015-07-07 |
Abbvie Biotechnology Ltd |
Vetor recombinante de expressão, e célula hospedeira procariótica.
|
ES2395214T3
(es)
|
1996-03-04 |
2013-02-11 |
The Penn State Research Foundation |
Materiales y métodos para aumentar la internalización celular
|
BR9707953A
(pt)
|
1996-03-05 |
2000-10-24 |
Childrens Hosp Medical Center |
Derivados de mercapto como inibidores de ciclooxigenases
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
US5855913A
(en)
|
1997-01-16 |
1999-01-05 |
Massachusetts Instite Of Technology |
Particles incorporating surfactants for pulmonary drug delivery
|
US5985309A
(en)
|
1996-05-24 |
1999-11-16 |
Massachusetts Institute Of Technology |
Preparation of particles for inhalation
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
GB9616105D0
(en)
|
1996-07-31 |
1996-09-11 |
Univ Kingston |
TrkA binding site of NGF
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
IL129475A0
(en)
|
1996-10-21 |
2000-02-29 |
Allelix Biopharma |
Neurotrophin antagonist compositions
|
US6284794B1
(en)
|
1996-11-05 |
2001-09-04 |
Head Explorer Aps |
Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase
|
AU5702298A
(en)
|
1996-12-03 |
1998-06-29 |
Abgenix, Inc. |
Transgenic mammals having human Ig loci including plural VH and VK regions nd antibodies produced therefrom
|
WO1998031346A1
(en)
|
1997-01-16 |
1998-07-23 |
Massachusetts Institute Of Technology |
Preparation of particles for inhalation
|
CN1238366C
(zh)
|
1997-01-21 |
2006-01-25 |
综合医院公司 |
利用rna-蛋白融合体筛选蛋白
|
US6194167B1
(en)
|
1997-02-18 |
2001-02-27 |
Washington State University Research Foundation |
ω-3 fatty acid desaturase
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
WO1999006834A2
(en)
|
1997-08-04 |
1999-02-11 |
Ixsys, Incorporated |
Methods for identifying ligand specific binding molecules
|
US5989463A
(en)
|
1997-09-24 |
1999-11-23 |
Alkermes Controlled Therapeutics, Inc. |
Methods for fabricating polymer-based controlled release devices
|
SE512663C2
(sv)
|
1997-10-23 |
2000-04-17 |
Biogram Ab |
Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
|
AU2978899A
(en)
|
1998-03-03 |
1999-09-20 |
Abgenix, Inc. |
Cd147 binding molecules as therapeutics
|
US6504013B1
(en)
|
2000-02-01 |
2003-01-07 |
Idexx Laboratories, Inc. |
Canine allergy therapeutic recombinant chimeric anti-IgE monoclonal antibody
|
GB9807781D0
(en)
|
1998-04-09 |
1998-06-10 |
Univ Bristol |
Therapeutic agent
|
US20020029391A1
(en)
|
1998-04-15 |
2002-03-07 |
Claude Geoffrey Davis |
Epitope-driven human antibody production and gene expression profiling
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
ATE238768T1
(de)
|
1998-06-24 |
2003-05-15 |
Advanced Inhalation Res Inc |
Grosse poröse partikel ausgestossen von einem inhalator
|
CA2341029A1
(en)
|
1998-08-17 |
2000-02-24 |
Abgenix, Inc. |
Generation of modified molecules with increased serum half-lives
|
PT2112166T
(pt)
|
1998-12-23 |
2019-01-30 |
Pfizer |
Anticorpos monoclonais humanos contra ctla-4
|
ATE295883T1
(de)
|
1999-03-18 |
2005-06-15 |
Merck Patent Gmbh |
Plättchenadhäsion blockierendes protein
|
CA2796140A1
(en)
|
1999-03-25 |
2000-09-28 |
Jochen Salfeld |
Human antibodies that bind human il-12 and methods for producing
|
US6492380B1
(en)
|
1999-05-17 |
2002-12-10 |
Queen's University At Kingston |
Method of inhibiting neurotrophin-receptor binding
|
IT1306704B1
(it)
|
1999-05-26 |
2001-10-02 |
Sirs Societa Italiana Per La R |
Anticorpi monoclonali e suoi derivati sintetici o biotecnologici ingrado di agire come molecole antagoniste per il ngf.
|
US6399780B1
(en)
|
1999-08-20 |
2002-06-04 |
Cephalon, Inc. |
Isomeric fused pyrrolocarbazoles and isoindolones
|
US6548062B2
(en)
|
2000-02-29 |
2003-04-15 |
Cephalon, Inc. |
Method of treating cancer with anti-neurotrophin agents
|
EP1130098A3
(en)
|
2000-02-29 |
2003-09-10 |
Pfizer Products Inc. |
Mammalian osteoregulins
|
US6703360B2
(en)
|
2000-04-07 |
2004-03-09 |
Heska Corporation |
Compositions and methods related to canine IgG and canine IL-13 receptors
|
FR2807660A1
(fr)
|
2000-04-13 |
2001-10-19 |
Warner Lambert Co |
Utilisation d'antagonistes du ngf pour la prevention ou le traitement de douleurs viscerales chroniques
|
JP2003533187A
(ja)
|
2000-05-03 |
2003-11-11 |
アムジエン・インコーポレーテツド |
治療薬としてのFcドメインを含む修飾ペプチド
|
US7022484B2
(en)
|
2000-06-08 |
2006-04-04 |
Board Of Regents, The University Of Texas System |
Methods for treating neuropathological states and neurogenic inflammatory states and methods for identifying compounds useful therein
|
US7220840B2
(en)
|
2000-06-16 |
2007-05-22 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator protein
|
US7449308B2
(en)
|
2000-06-28 |
2008-11-11 |
Glycofi, Inc. |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
|
EP1297172B1
(en)
|
2000-06-28 |
2005-11-09 |
Glycofi, Inc. |
Methods for producing modified glycoproteins
|
CA2433353C
(en)
|
2000-12-28 |
2017-03-21 |
Altus Biologics, Inc. |
Crystals of whole antibodies and fragments thereof and methods for making and using them
|
US7117096B2
(en)
|
2001-04-17 |
2006-10-03 |
Abmaxis, Inc. |
Structure-based selection and affinity maturation of antibody library
|
US7727527B2
(en)
*
|
2001-05-30 |
2010-06-01 |
Genentech, Inc. |
Anti-NGF antibodies for the therapeutic treatments
|
AU2002310441A1
(en)
|
2001-06-14 |
2003-01-02 |
The Regents Of The University Of California |
A novel signaling pathway for the production of inflammatory pain and neuropathy
|
US20030031671A1
(en)
|
2001-08-01 |
2003-02-13 |
Sydney Welt |
Methods of treating colon cancer utilizing tumor-specific antibodies
|
WO2003022261A1
(en)
|
2001-09-13 |
2003-03-20 |
Miller Kenneth E |
Method of alleviating pain
|
PT1438400E
(pt)
|
2001-10-01 |
2009-09-10 |
Dyax Corp |
Vectores de apresentação eucarióticos de cadeias múltiplas e suas utilizações
|
US7393648B2
(en)
|
2001-12-03 |
2008-07-01 |
Alexion Pharmaceuticals, Inc. |
Hybrid antibodies
|
WO2003060080A2
(en)
*
|
2001-12-21 |
2003-07-24 |
Idexx Laboratories, Inc. |
Canine immunoglobulin variable domains, caninized antibodies, and methods for making and using them
|
US20060078533A1
(en)
|
2004-10-12 |
2006-04-13 |
Omoigui Osemwota S |
Method of prevention and treatment of aging and age-related disorders including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimer's disease and cancer
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
US20060147450A1
(en)
|
2002-10-04 |
2006-07-06 |
Shelton David L |
Methods for treating cardiac arrhythmia and preventing death due to cardiac arrhythmia using ngf antagonists
|
UA80447C2
(en)
|
2002-10-08 |
2007-09-25 |
|
Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
|
AU2003304238A1
(en)
|
2002-10-08 |
2005-01-13 |
Rinat Neuroscience Corp. |
Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same
|
DK1556083T3
(da)
|
2002-10-08 |
2011-04-04 |
Rinat Neuroscience Corp |
Fremgangsmåde til behandling af post-operative smerter ved indgivelse af en antistof mod nervevækstfaktor og sammensætning indeholdende samme
|
WO2004058184A2
(en)
|
2002-12-24 |
2004-07-15 |
Rinat Neuroscience Corp. |
Anti-ngf antibodies and methods using same
|
US7569364B2
(en)
|
2002-12-24 |
2009-08-04 |
Pfizer Inc. |
Anti-NGF antibodies and methods using same
|
WO2004065560A2
(en)
|
2003-01-18 |
2004-08-05 |
Rinat Neuroscience Corp. |
Methods of screening for modulators of nerve growth factor
|
EP1594441B1
(en)
|
2003-02-19 |
2010-12-15 |
Rinat Neuroscience Corp. |
Method for treating pain by administering a nerve growth factor antagonist and an nsaid and composition containing the same
|
SI1648509T1
(sl)
|
2003-07-15 |
2012-12-31 |
Amgen Inc. |
Humana protitelesa, ki nevtralizirajo anti-ngf, kot selektivni inhibitorji poti nfg
|
JP2007528723A
(ja)
|
2003-08-22 |
2007-10-18 |
メディミューン,インコーポレーテッド |
抗体のヒト化
|
ITRM20030601A1
(it)
|
2003-12-24 |
2005-06-25 |
Lay Line Genomics Spa |
Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
|
PL1732949T3
(pl)
|
2004-04-07 |
2010-06-30 |
Rinat Neuroscience Corp |
Sposoby leczenia nowotworowego bólu kości przez podawanie antagonisty czynnika wzrostu nerwów
|
JP5096167B2
(ja)
|
2005-01-24 |
2012-12-12 |
メドイミューン リミテッド |
Ngfに対する特異的結合メンバー
|
WO2006108863A2
(en)
|
2005-04-13 |
2006-10-19 |
Thomson Licensing |
Process for scalable coding of images
|
ITRM20050290A1
(it)
|
2005-06-07 |
2006-12-08 |
Lay Line Genomics Spa |
Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
SG175622A1
(en)
|
2006-10-13 |
2011-11-28 |
Centocor Ortho Biotech Inc |
Enhancement of hybridoma fusion efficiencies through cell synchronization
|
MX2010001395A
(es)
*
|
2007-08-10 |
2010-03-10 |
Regeneron Pharma |
Anticuerpos humanos de alta afinidad de factor de crecimiento de nervio humano.
|
KR101499278B1
(ko)
|
2007-12-17 |
2015-03-06 |
화이자 리미티드 |
간질성 방광염의 치료
|
WO2009091912A2
(en)
|
2008-01-15 |
2009-07-23 |
Abbott Laboratories |
Improved mammalian expression vectors and uses thereof
|
US20110257244A1
(en)
|
2008-01-18 |
2011-10-20 |
Alnylam Pharmaceuticals, Inc. |
Chemically modified oligonucleotides and small molecules for use in reducing micro rna activity levels and uses thereof
|
JP5470817B2
(ja)
|
2008-03-10 |
2014-04-16 |
日産自動車株式会社 |
電池用電極およびこれを用いた電池、並びにその製造方法
|
WO2009150623A1
(en)
*
|
2008-06-13 |
2009-12-17 |
Pfizer Inc |
Treatment of chronic prostatitis
|
WO2010027488A2
(en)
|
2008-09-04 |
2010-03-11 |
Vet Therapeutics, Inc. |
Monoclonal antibodies
|
JP6136279B2
(ja)
|
2013-01-15 |
2017-05-31 |
株式会社ジェイテクト |
転がり軸受装置
|
TWI503850B
(zh)
|
2013-03-22 |
2015-10-11 |
Polytronics Technology Corp |
過電流保護元件
|
TWI510996B
(zh)
|
2013-10-03 |
2015-12-01 |
Acer Inc |
控制觸控面板的方法以及使用該方法的可攜式電腦
|
US9816280B1
(en)
|
2016-11-02 |
2017-11-14 |
Matthew Reitnauer |
Portable floor
|