DK1117401T3 - Antibiotisk præparat til øjenbehandling - Google Patents

Antibiotisk præparat til øjenbehandling

Info

Publication number
DK1117401T3
DK1117401T3 DK99956504T DK99956504T DK1117401T3 DK 1117401 T3 DK1117401 T3 DK 1117401T3 DK 99956504 T DK99956504 T DK 99956504T DK 99956504 T DK99956504 T DK 99956504T DK 1117401 T3 DK1117401 T3 DK 1117401T3
Authority
DK
Denmark
Prior art keywords
eye treatment
antibiotic preparation
antibiotic
preparation
eye
Prior art date
Application number
DK99956504T
Other languages
Danish (da)
English (en)
Inventor
Gerald Cagle
Robert L Abshire
David W Stroman
John M Yanni
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26799441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1117401(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of DK1117401T3 publication Critical patent/DK1117401T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK99956504T 1998-09-30 1999-09-29 Antibiotisk præparat til øjenbehandling DK1117401T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10250698P 1998-09-30 1998-09-30
US10250498P 1998-09-30 1998-09-30
PCT/US1999/022622 WO2000018386A2 (en) 1998-09-30 1999-09-29 Antibiotic compositions for treatment of the eye, ear and nose

Publications (1)

Publication Number Publication Date
DK1117401T3 true DK1117401T3 (da) 2004-02-23

Family

ID=26799441

Family Applications (5)

Application Number Title Priority Date Filing Date
DK99956504T DK1117401T3 (da) 1998-09-30 1999-09-29 Antibiotisk præparat til øjenbehandling
DK14176366.4T DK2796138T3 (en) 1998-09-30 1999-09-29 Antibiotic compositions for the treatment of conjunctivitis
DK03020587.6T DK1384478T3 (da) 1998-09-30 1999-09-29 Antibiotiske sammensætninger indeholdende moxifloxacin til behandling af øjet
DK10178657.2T DK2301541T3 (da) 1998-09-30 1999-09-29 Antibiotiske sammensætninger til behandling af øjet
DK10176412.4T DK2269602T3 (en) 1998-09-30 1999-09-29 Antibiotic COMPOSITIONS FOR TREATMENT OF EAR

Family Applications After (4)

Application Number Title Priority Date Filing Date
DK14176366.4T DK2796138T3 (en) 1998-09-30 1999-09-29 Antibiotic compositions for the treatment of conjunctivitis
DK03020587.6T DK1384478T3 (da) 1998-09-30 1999-09-29 Antibiotiske sammensætninger indeholdende moxifloxacin til behandling af øjet
DK10178657.2T DK2301541T3 (da) 1998-09-30 1999-09-29 Antibiotiske sammensætninger til behandling af øjet
DK10176412.4T DK2269602T3 (en) 1998-09-30 1999-09-29 Antibiotic COMPOSITIONS FOR TREATMENT OF EAR

Country Status (18)

Country Link
EP (5) EP2269602B1 (cs)
JP (5) JP2002525317A (cs)
KR (1) KR101463243B1 (cs)
CN (2) CN100374114C (cs)
AR (2) AR020661A1 (cs)
AT (2) ATE501732T1 (cs)
AU (1) AU762827B2 (cs)
BR (1) BRPI9914151B1 (cs)
CA (3) CA2774207A1 (cs)
CY (3) CY1111404T1 (cs)
DE (2) DE69912972T2 (cs)
DK (5) DK1117401T3 (cs)
ES (4) ES2526521T3 (cs)
HK (1) HK1038691B (cs)
PT (5) PT1384478E (cs)
TR (2) TR200100883T2 (cs)
TW (1) TWI222361B (cs)
WO (1) WO2000018386A2 (cs)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
DE19937116A1 (de) 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
DE19937115A1 (de) 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
PT1214056E (pt) 1999-09-24 2004-02-27 Alcon Inc Formulacoes em suspensao topica que contem ciprofloxacina e dexametasona
DE19962470A1 (de) 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
WO2001089495A2 (en) * 2000-05-19 2001-11-29 Alcon Laboratories, Inc. Antibiotic compositions containing quinolone derivatives for treatment of the eye, ear and nose
AU2001276928A1 (en) 2000-07-26 2002-02-05 Alcon Universal Ltd. Improved process for manufacturing compositions containing ciprofloxacin and hydrocortisone
WO2002040028A1 (fr) * 2000-11-16 2002-05-23 Wakamoto Pharmaceutical Co., Ltd. Gouttes pour les yeux en gel antibacterien
AU2002226926A1 (en) * 2000-12-20 2002-07-01 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
US7025958B2 (en) 2000-12-20 2006-04-11 Alcon, Inc. Use of amidoamines to treat or prevent acanthamoeba and fungal infections
US20030139382A1 (en) 2001-09-21 2003-07-24 Alcon, Inc. Method of treating middle ear infections
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
PT1666477E (pt) 2003-09-10 2013-08-28 Kyorin Seiyaku Kk Derivado de 7-(4-substituído-3-ciclopropilaminometil-1- pirrolidinil) quinolonecarboxílico
WO2006015545A1 (fr) * 2004-08-11 2006-02-16 Shenzhen Tys R & D Co., Ltd. Capsule de gelatine de moxifloxacin et procede pour sa preparation
MX2007002462A (es) * 2004-09-03 2007-10-10 Piedmont Pharmaceuticals Llc Metodo para el tratamiento de transmembrana y prevencion de la otitis media.
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
AU2005317228A1 (en) * 2004-12-10 2006-06-22 Alcon, Inc. Compositions for treatment of ear infections
CN101317847B (zh) * 2007-06-06 2010-10-13 深圳市瑞谷医药技术有限公司 一种眼用或耳鼻用药物组合物及其用途
TWI544934B (zh) * 2008-06-09 2016-08-11 愛爾康研究有限公司 含有氟喹諾酮抗生素藥物之經改良藥學組成物
TWI460181B (zh) * 2009-07-02 2014-11-11 Alcon Res Ltd 用於治療眼部、耳部或鼻部感染之組成物及方法
SI2521547T1 (en) * 2010-01-07 2018-02-28 Regents Of The University Of Minnesota Method and compositions for the introduction of moxifloxacin into the ear
BR112014012885A2 (pt) 2011-12-06 2017-06-13 Alcon Res Ltd composição de gel celulósica com estabilidade de viscosidade aperfeiçoada
RU2472507C1 (ru) * 2012-02-01 2013-01-20 Закрытое акционерное общество "Брынцалов-А" Водный состав на основе моксифлоксацина для парентерального введения
US9504691B2 (en) * 2012-12-06 2016-11-29 Alcon Research, Ltd. Finafloxacin suspension compositions
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
CN104224802B (zh) * 2014-09-19 2017-12-12 南京优科生物医药研究有限公司 一种盐酸莫西沙星滴耳剂及其制备方法
RU2595837C2 (ru) * 2014-09-29 2016-08-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазных капель
CN108348516B (zh) * 2015-10-29 2021-02-12 特一华制药株式会社 外用剂
US20210386759A1 (en) * 2020-06-10 2021-12-16 Ocular Science, Inc. Compositions and methods for post-operative ocular care
WO2019193513A1 (en) * 2018-04-03 2019-10-10 Hyderabad Eye Research Foundation Mucoadhesive drug delivery system for ocular administration of fluoroquinolone antibiotics
IT201900005280A1 (it) * 2019-04-05 2020-10-05 Ntc S R L Composizione otologica
CN116270662A (zh) * 2021-12-03 2023-06-23 苏州欧康维视生物科技有限公司 盐酸莫西沙星地塞米松磷酸钠滴眼液
KR102656260B1 (ko) 2022-10-14 2024-04-09 주식회사태준제약 목시플록사신을 포함하는 안과용 조성물

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223493A (en) 1984-12-28 1993-06-29 Alcon Laboratories, Inc. Anti-inflammatory compounds for ophthalmic use
US4910225A (en) * 1988-01-27 1990-03-20 Senju Pharmaceutical Co., Ltd. Locally administrable therapeutic composition for inflammatory disease
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
WO1990001933A1 (en) 1988-08-26 1990-03-08 Alcon Laboratories, Inc. Combination of quinolone antibiotics and steroids for topical ophthalmic use
JPH03109236A (ja) * 1989-09-22 1991-05-09 Hoya Corp 半導体超微粒子分散ガラスの製造方法
JPH085779B2 (ja) * 1989-09-22 1996-01-24 杏林製薬株式会社 フレロキサシン点眼液
TW209865B (cs) * 1992-01-10 1993-07-21 Bayer Ag
ATE300936T1 (de) 1992-05-06 2005-08-15 Alcon Lab Inc Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen
DE4424369A1 (de) * 1994-07-11 1996-01-18 Bayer Ag Pyrido[3,2,1.i,j][3,1]benzoxazinderivate
JPH0892241A (ja) * 1994-09-22 1996-04-09 Ss Pharmaceut Co Ltd ５−ヒドラジノキノロンカルボン酸誘導体及びこれを有効成分とする抗菌剤
US5631287A (en) 1994-12-22 1997-05-20 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
DE69620136T2 (de) * 1995-06-06 2002-08-01 Bayer Ag Antibakterielle präparate für die ohren ohne irritierende, sensibilisierende und ototoxische wirkungen
JP3290914B2 (ja) * 1997-03-17 2002-06-10 参天製薬株式会社 眼組織におけるキノロン系抗菌剤の定量装置
SI1017392T1 (en) * 1997-09-25 2002-12-31 Bayer Aktiengesellschaft Medicament formulation with a controlled release of an active agent
BR9913890B1 (pt) 1998-09-23 2010-10-19 composição de cuidado oral e uso de um complexo de cobre ligado a maltol, hinoquitiol ou etilmatol.
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US20020001617A1 (en) * 2000-05-26 2002-01-03 Chang-Hyun Lee Rapidly disintegrating tablet and process for the manufacture thereof

Also Published As

Publication number Publication date
EP1384478B1 (en) 2011-03-16
ES2519190T3 (es) 2014-11-06
EP2796138B1 (en) 2016-08-17
EP2269602B1 (en) 2014-11-19
CN1320035A (zh) 2001-10-31
PT1384478E (pt) 2011-05-12
TWI222361B (en) 2004-10-21
EP1384478A1 (en) 2004-01-28
JP2002525317A (ja) 2002-08-13
ES2602956T3 (es) 2017-02-23
ATE501732T1 (de) 2011-04-15
CY1115759T1 (el) 2017-01-25
EP1117401A2 (en) 2001-07-25
BR9914151A (pt) 2001-06-26
DE69912972T2 (de) 2004-04-22
PT2301541E (pt) 2014-10-29
PT1117401E (pt) 2004-03-31
DK2301541T3 (da) 2014-09-01
AU762827B2 (en) 2003-07-03
EP2301541A1 (en) 2011-03-30
HK1150769A1 (en) 2012-01-13
DK2269602T3 (en) 2014-12-15
CY1115916T1 (el) 2017-01-25
CA2342211A1 (en) 2000-04-06
PT2269602E (pt) 2014-12-29
HK1038691B (en) 2004-04-23
DE69943287D1 (de) 2011-04-28
ES2526521T3 (es) 2015-01-13
EP2796138A1 (en) 2014-10-29
EP2269602A1 (en) 2011-01-05
HK1150756A1 (en) 2012-01-13
JP5563041B2 (ja) 2014-07-30
JP2014144982A (ja) 2014-08-14
WO2000018386A3 (en) 2000-06-08
KR20010075138A (ko) 2001-08-09
JP2013018799A (ja) 2013-01-31
JP2012067141A (ja) 2012-04-05
HK1059572A1 (en) 2004-07-09
ES2207307T3 (es) 2004-05-16
CN1650863A (zh) 2005-08-10
DK2796138T3 (en) 2016-12-05
DK1384478T3 (da) 2011-05-23
CY1111404T1 (el) 2015-08-05
CN100374114C (zh) 2008-03-12
CA2342211C (en) 2009-05-26
EP1117401B1 (en) 2003-11-19
WO2000018386A2 (en) 2000-04-06
AR020661A1 (es) 2002-05-22
EP2301541B1 (en) 2014-08-20
PT2796138T (pt) 2016-09-22
ATE254458T1 (de) 2003-12-15
BRPI9914151B1 (pt) 2017-10-03
AR081393A2 (es) 2012-08-29
CA2659064A1 (en) 2000-04-06
AU1310100A (en) 2000-04-17
HK1038691A1 (en) 2002-03-28
TR200704370T2 (tr) 2007-11-21
TR200100883T2 (tr) 2001-10-22
DE69912972D1 (de) 2003-12-24
BRPI9914151B8 (cs) 2021-05-25
CA2774207A1 (en) 2000-04-06
CN1184968C (zh) 2005-01-19
JP2009007375A (ja) 2009-01-15
KR101463243B1 (ko) 2014-12-17

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