CY1115916T1 - Αντιβιοτικες συνθεσεις για θεραπεια του αυτιου - Google Patents

Αντιβιοτικες συνθεσεις για θεραπεια του αυτιου

Info

Publication number
CY1115916T1
CY1115916T1 CY20151100023T CY151100023T CY1115916T1 CY 1115916 T1 CY1115916 T1 CY 1115916T1 CY 20151100023 T CY20151100023 T CY 20151100023T CY 151100023 T CY151100023 T CY 151100023T CY 1115916 T1 CY1115916 T1 CY 1115916T1
Authority
CY
Cyprus
Prior art keywords
compositions
antibiotic compositions
early therapy
ophthalmic
nasal
Prior art date
Application number
CY20151100023T
Other languages
English (en)
Inventor
Gerald Cagle
Robert L Abshire
David W Stromann
John M Yanni
Original Assignee
Alcon Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26799441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1115916(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Pharmaceuticals Ltd. filed Critical Alcon Pharmaceuticals Ltd.
Publication of CY1115916T1 publication Critical patent/CY1115916T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Αποκαλύπτονται οφθαλμολογικές, ωτιαίες και ρινικές συνθέσεις περιέχοντας μία νέα κατηγορία αντιβιοτικών (π.χ. μοξιφλοξασίνη). Οι συνθέσεις περιέχουν ακόμα κατά προτίμηση ένα ή περισσότερους αντιφλεγμονώδεις παράγοντες. Οι συνθέσεις μπορούν να χρησιμοποιηθούν για να θεραπεύσουν οφθαλμολογικές, ωτιαίες και ρινικές παθήσεις με τη τοπική εφαρμογή των συνθέσεων στους νοσούντες ιστούς.
CY20151100023T 1998-09-30 2015-01-09 Αντιβιοτικες συνθεσεις για θεραπεια του αυτιου CY1115916T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10250498P 1998-09-30 1998-09-30
US10250698P 1998-09-30 1998-09-30
EP10176412.4A EP2269602B1 (en) 1998-09-30 1999-09-29 Antibiotic compositions for treatment of the ear

Publications (1)

Publication Number Publication Date
CY1115916T1 true CY1115916T1 (el) 2017-01-25

Family

ID=26799441

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20111100409T CY1111404T1 (el) 1998-09-30 2011-04-21 Αντιβιοτικες συνθεσεις οι οποιες πeριεχουν παραγωγα μοξιφλοξασινης για θεραπεια του οφθαλμου
CY20141100819T CY1115759T1 (el) 1998-09-30 2014-10-09 Αντιβιοτικες συνθεσεις για θεραπεια του οφθαλμου
CY20151100023T CY1115916T1 (el) 1998-09-30 2015-01-09 Αντιβιοτικες συνθεσεις για θεραπεια του αυτιου

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CY20111100409T CY1111404T1 (el) 1998-09-30 2011-04-21 Αντιβιοτικες συνθεσεις οι οποιες πeριεχουν παραγωγα μοξιφλοξασινης για θεραπεια του οφθαλμου
CY20141100819T CY1115759T1 (el) 1998-09-30 2014-10-09 Αντιβιοτικες συνθεσεις για θεραπεια του οφθαλμου

Country Status (18)

Country Link
EP (5) EP1384478B1 (el)
JP (5) JP2002525317A (el)
KR (1) KR101463243B1 (el)
CN (2) CN100374114C (el)
AR (2) AR020661A1 (el)
AT (2) ATE501732T1 (el)
AU (1) AU762827B2 (el)
BR (1) BRPI9914151B1 (el)
CA (3) CA2659064A1 (el)
CY (3) CY1111404T1 (el)
DE (2) DE69912972T2 (el)
DK (5) DK2796138T3 (el)
ES (4) ES2602956T3 (el)
HK (4) HK1150756A1 (el)
PT (5) PT1384478E (el)
TR (2) TR200100883T2 (el)
TW (1) TWI222361B (el)
WO (1) WO2000018386A2 (el)

Families Citing this family (35)

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US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
DE19937116A1 (de) 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
DE19937115A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
PL201130B1 (pl) 1999-09-24 2009-03-31 Alcon Inc Kompozycje zawiesinowe zawierające ciprofloksacynę i deksametazon do podawania miejscowego do oczu, uszu lub nosa
DE19962470A1 (de) 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
AU2001261748A1 (en) * 2000-05-19 2001-12-03 Alcon Laboratories Inc. Antibiotic compositions for treatment of the eye, ear and nose
CA2412575C (en) 2000-07-26 2009-12-29 Onkar N. Singh Improved process for manufacturing compositions containing ciprofloxacin and hydrocortisone
AU2002214308A1 (en) * 2000-11-16 2002-05-27 Wakamoto Pharmaceutical Co., Ltd. Antibacterial gel eye drops
AU2002226926A1 (en) * 2000-12-20 2002-07-01 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
US7025958B2 (en) 2000-12-20 2006-04-11 Alcon, Inc. Use of amidoamines to treat or prevent acanthamoeba and fungal infections
EP1429780B1 (en) 2001-09-21 2005-12-21 Alcon, Inc. Method of treating middle ear infections
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
WO2006015545A1 (fr) * 2004-08-11 2006-02-16 Shenzhen Tys R & D Co., Ltd. Capsule de gelatine de moxifloxacin et procede pour sa preparation
EP1784164A4 (en) * 2004-09-03 2008-07-09 Piedmont Pharmaceuticals Llc PROCESS FOR TRANSMEMBRANE TREATMENT AND PREVENTION OF OTITIS MEDIA
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CN101317847B (zh) * 2007-06-06 2010-10-13 深圳市瑞谷医药技术有限公司 一种眼用或耳鼻用药物组合物及其用途
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US9138481B2 (en) 2011-12-06 2015-09-22 Alcon Research, Ltd. Cellulosic gel composition with improved viscosity stability
RU2472507C1 (ru) * 2012-02-01 2013-01-20 Закрытое акционерное общество "Брынцалов-А" Водный состав на основе моксифлоксацина для парентерального введения
US9504691B2 (en) * 2012-12-06 2016-11-29 Alcon Research, Ltd. Finafloxacin suspension compositions
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
CN104224802B (zh) * 2014-09-19 2017-12-12 南京优科生物医药研究有限公司 一种盐酸莫西沙星滴耳剂及其制备方法
RU2595837C2 (ru) * 2014-09-29 2016-08-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазных капель
TWI713618B (zh) * 2015-10-29 2020-12-21 日商帝化製藥股份有限公司 外用劑
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ID28630A (id) 1998-09-23 2001-06-21 Unilever Nv Komposisi-komposisi perawatan oral
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Also Published As

Publication number Publication date
ES2526521T3 (es) 2015-01-13
KR20010075138A (ko) 2001-08-09
JP2002525317A (ja) 2002-08-13
CA2342211C (en) 2009-05-26
PT2269602E (pt) 2014-12-29
ES2602956T3 (es) 2017-02-23
DK2796138T3 (en) 2016-12-05
HK1038691A1 (en) 2002-03-28
EP2269602A1 (en) 2011-01-05
EP1384478B1 (en) 2011-03-16
EP2269602B1 (en) 2014-11-19
PT1117401E (pt) 2004-03-31
CY1111404T1 (el) 2015-08-05
PT1384478E (pt) 2011-05-12
DE69912972T2 (de) 2004-04-22
CN1650863A (zh) 2005-08-10
TR200100883T2 (tr) 2001-10-22
ES2519190T3 (es) 2014-11-06
EP2796138B1 (en) 2016-08-17
WO2000018386A2 (en) 2000-04-06
CN100374114C (zh) 2008-03-12
BRPI9914151B8 (el) 2021-05-25
CA2659064A1 (en) 2000-04-06
CN1320035A (zh) 2001-10-31
EP2796138A1 (en) 2014-10-29
CA2342211A1 (en) 2000-04-06
AR020661A1 (es) 2002-05-22
KR101463243B1 (ko) 2014-12-17
DK2269602T3 (en) 2014-12-15
HK1059572A1 (en) 2004-07-09
ATE501732T1 (de) 2011-04-15
DE69943287D1 (de) 2011-04-28
DK1384478T3 (da) 2011-05-23
PT2301541E (pt) 2014-10-29
ES2207307T3 (es) 2004-05-16
BR9914151A (pt) 2001-06-26
AU762827B2 (en) 2003-07-03
TR200704370T2 (tr) 2007-11-21
EP1117401B1 (en) 2003-11-19
DK2301541T3 (da) 2014-09-01
EP2301541B1 (en) 2014-08-20
HK1150769A1 (en) 2012-01-13
HK1038691B (zh) 2004-04-23
JP2012067141A (ja) 2012-04-05
CA2774207A1 (en) 2000-04-06
TWI222361B (en) 2004-10-21
JP2013018799A (ja) 2013-01-31
DK1117401T3 (da) 2004-02-23
JP2009007375A (ja) 2009-01-15
JP2014144982A (ja) 2014-08-14
EP2301541A1 (en) 2011-03-30
CN1184968C (zh) 2005-01-19
WO2000018386A3 (en) 2000-06-08
BRPI9914151B1 (pt) 2017-10-03
AU1310100A (en) 2000-04-17
JP5563041B2 (ja) 2014-07-30
CY1115759T1 (el) 2017-01-25
EP1117401A2 (en) 2001-07-25
PT2796138T (pt) 2016-09-22
HK1150756A1 (en) 2012-01-13
AR081393A2 (es) 2012-08-29
EP1384478A1 (en) 2004-01-28
ATE254458T1 (de) 2003-12-15
DE69912972D1 (de) 2003-12-24

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