ATE254458T1 - Antibiotische zusammensetzungen zur behandlung des auges - Google Patents

Antibiotische zusammensetzungen zur behandlung des auges

Info

Publication number
ATE254458T1
ATE254458T1 AT99956504T AT99956504T ATE254458T1 AT E254458 T1 ATE254458 T1 AT E254458T1 AT 99956504 T AT99956504 T AT 99956504T AT 99956504 T AT99956504 T AT 99956504T AT E254458 T1 ATE254458 T1 AT E254458T1
Authority
AT
Austria
Prior art keywords
eye
treating
antibiotic compositions
antibiotic
compositions
Prior art date
Application number
AT99956504T
Other languages
English (en)
Inventor
Gerald Cagle
Robert L Abshire
David W Stroman
John M Yanni
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26799441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE254458(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of ATE254458T1 publication Critical patent/ATE254458T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0046Ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT99956504T 1998-09-30 1999-09-29 Antibiotische zusammensetzungen zur behandlung des auges ATE254458T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10250698P 1998-09-30 1998-09-30
US10250498P 1998-09-30 1998-09-30
PCT/US1999/022622 WO2000018386A2 (en) 1998-09-30 1999-09-29 Antibiotic compositions for treatment of the eye, ear and nose

Publications (1)

Publication Number Publication Date
ATE254458T1 true ATE254458T1 (de) 2003-12-15

Family

ID=26799441

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03020587T ATE501732T1 (de) 1998-09-30 1999-09-29 Antibiotische zusammensetzung, die moxifloxacin enthält, zur behandlung von augen
AT99956504T ATE254458T1 (de) 1998-09-30 1999-09-29 Antibiotische zusammensetzungen zur behandlung des auges

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03020587T ATE501732T1 (de) 1998-09-30 1999-09-29 Antibiotische zusammensetzung, die moxifloxacin enthält, zur behandlung von augen

Country Status (18)

Country Link
EP (5) EP2269602B1 (de)
JP (5) JP2002525317A (de)
KR (1) KR101463243B1 (de)
CN (2) CN100374114C (de)
AR (2) AR020661A1 (de)
AT (2) ATE501732T1 (de)
AU (1) AU762827B2 (de)
BR (1) BRPI9914151B1 (de)
CA (3) CA2659064A1 (de)
CY (3) CY1111404T1 (de)
DE (2) DE69912972T2 (de)
DK (5) DK2796138T3 (de)
ES (4) ES2519190T3 (de)
HK (4) HK1150756A1 (de)
PT (5) PT2269602E (de)
TR (2) TR200100883T2 (de)
TW (1) TWI222361B (de)
WO (1) WO2000018386A2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
DE19937115A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
AU776609B2 (en) 1999-09-24 2004-09-16 Novartis Ag Topical suspension formulations containing ciprofloxacin and dexamethasone
DE19962470A1 (de) * 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
AU2001261748A1 (en) * 2000-05-19 2001-12-03 Alcon Laboratories Inc. Antibiotic compositions for treatment of the eye, ear and nose
US6462033B2 (en) 2000-07-26 2002-10-08 Alcon Universal Ltd. Process for manufacturing compositions containing ciprofloxacin and hydrocortisone
WO2002040028A1 (fr) * 2000-11-16 2002-05-23 Wakamoto Pharmaceutical Co., Ltd. Gouttes pour les yeux en gel antibacterien
AU2002226926A1 (en) * 2000-12-20 2002-07-01 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
WO2002049633A2 (en) 2000-12-20 2002-06-27 Alcon, Inc. Use of amidoamines to treat or prevent acanthamoeba and fungal infections
CN1231218C (zh) 2001-09-21 2005-12-14 爱尔康公司 药物组合物在制备用于治疗中耳感染的药物中的用途
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
WO2006015545A1 (fr) * 2004-08-11 2006-02-16 Shenzhen Tys R & D Co., Ltd. Capsule de gelatine de moxifloxacin et procede pour sa preparation
EP1784164A4 (de) * 2004-09-03 2008-07-09 Piedmont Pharmaceuticals Llc Verfahren zur transmembranbehandlung und vorbeugung von otitis media
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
CA2587081A1 (en) * 2004-12-10 2006-06-22 Alcon, Inc. Compositions for treatment of ear infections
CN101317847B (zh) * 2007-06-06 2010-10-13 深圳市瑞谷医药技术有限公司 一种眼用或耳鼻用药物组合物及其用途
TWI544934B (zh) * 2008-06-09 2016-08-11 愛爾康研究有限公司 含有氟喹諾酮抗生素藥物之經改良藥學組成物
US8536167B2 (en) * 2009-07-02 2013-09-17 Alcon Research, Ltd. Methods for treating ophthalmic, otic, or nasal infections
HUE035586T2 (en) * 2010-01-07 2018-05-28 Univ Minnesota Methods and Preparations for the Use of Moxifloxacin in the Ears
US9138481B2 (en) 2011-12-06 2015-09-22 Alcon Research, Ltd. Cellulosic gel composition with improved viscosity stability
RU2472507C1 (ru) * 2012-02-01 2013-01-20 Закрытое акционерное общество "Брынцалов-А" Водный состав на основе моксифлоксацина для парентерального введения
US9504691B2 (en) 2012-12-06 2016-11-29 Alcon Research, Ltd. Finafloxacin suspension compositions
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
CN104224802B (zh) * 2014-09-19 2017-12-12 南京优科生物医药研究有限公司 一种盐酸莫西沙星滴耳剂及其制备方法
RU2595837C2 (ru) * 2014-09-29 2016-08-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазных капель
JP6474913B2 (ja) * 2015-10-29 2019-02-27 テイカ製薬株式会社 外用剤
US20210038612A1 (en) * 2018-04-03 2021-02-11 Hyderabad Eye Research Foundation Mucoadhesive drug delivery system for ocular administration of fluoroquinolone antibiotics
IT201900005280A1 (it) * 2019-04-05 2020-10-05 Ntc S R L Composizione otologica
CA3182196A1 (en) * 2020-06-10 2021-12-16 Anthony Sampietro Compositions and uses in method for post-operative ocular care
KR102656260B1 (ko) 2022-10-14 2024-04-09 주식회사태준제약 목시플록사신을 포함하는 안과용 조성물

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US5223493A (en) * 1984-12-28 1993-06-29 Alcon Laboratories, Inc. Anti-inflammatory compounds for ophthalmic use
CA1325382C (en) * 1988-01-27 1993-12-21 Takahiro Ogawa Locally administrable therapeutic composition for inflammatory disease
DE3906365A1 (de) 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
AU4201189A (en) * 1988-08-26 1990-03-23 Alcon Laboratories, Inc. Combination of quinolone antibiotics and steroids for topical ophthalmic use
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JPH03109236A (ja) * 1989-09-22 1991-05-09 Hoya Corp 半導体超微粒子分散ガラスの製造方法
TW209865B (de) * 1992-01-10 1993-07-21 Bayer Ag
EP0639070B2 (de) 1992-05-06 2010-09-08 Alcon Laboratories, Inc. Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen
DE4424369A1 (de) * 1994-07-11 1996-01-18 Bayer Ag Pyrido[3,2,1.i,j][3,1]benzoxazinderivate
JPH0892241A (ja) * 1994-09-22 1996-04-09 Ss Pharmaceut Co Ltd 5−ヒドラジノキノロンカルボン酸誘導体及びこれを有効成分とする抗菌剤
US5631287A (en) 1994-12-22 1997-05-20 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
DE69620136T2 (de) * 1995-06-06 2002-08-01 Bayer Ag Antibakterielle präparate für die ohren ohne irritierende, sensibilisierende und ototoxische wirkungen
JP3290914B2 (ja) * 1997-03-17 2002-06-10 参天製薬株式会社 眼組織におけるキノロン系抗菌剤の定量装置
CN1623533A (zh) * 1997-09-25 2005-06-08 拜尔公司 控释活性化合物的药物制剂
ATE290848T1 (de) 1998-09-23 2005-04-15 Unilever Nv Mundpflegemittel
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US20020001617A1 (en) * 2000-05-26 2002-01-03 Chang-Hyun Lee Rapidly disintegrating tablet and process for the manufacture thereof

Also Published As

Publication number Publication date
EP2301541A1 (de) 2011-03-30
CN1184968C (zh) 2005-01-19
EP1117401A2 (de) 2001-07-25
HK1038691A1 (en) 2002-03-28
EP2269602A1 (de) 2011-01-05
CN1320035A (zh) 2001-10-31
BRPI9914151B8 (de) 2021-05-25
PT1384478E (pt) 2011-05-12
DE69912972T2 (de) 2004-04-22
ES2602956T3 (es) 2017-02-23
EP2796138B1 (de) 2016-08-17
DE69912972D1 (de) 2003-12-24
CA2774207A1 (en) 2000-04-06
PT2301541E (pt) 2014-10-29
AR020661A1 (es) 2002-05-22
EP1384478A1 (de) 2004-01-28
DK1117401T3 (da) 2004-02-23
JP2013018799A (ja) 2013-01-31
AR081393A2 (es) 2012-08-29
EP1117401B1 (de) 2003-11-19
EP2301541B1 (de) 2014-08-20
EP1384478B1 (de) 2011-03-16
CN100374114C (zh) 2008-03-12
EP2796138A1 (de) 2014-10-29
ES2519190T3 (es) 2014-11-06
HK1150756A1 (en) 2012-01-13
JP5563041B2 (ja) 2014-07-30
DK2269602T3 (en) 2014-12-15
PT2796138T (pt) 2016-09-22
BR9914151A (pt) 2001-06-26
AU762827B2 (en) 2003-07-03
KR101463243B1 (ko) 2014-12-17
JP2009007375A (ja) 2009-01-15
ATE501732T1 (de) 2011-04-15
AU1310100A (en) 2000-04-17
WO2000018386A3 (en) 2000-06-08
ES2207307T3 (es) 2004-05-16
JP2002525317A (ja) 2002-08-13
EP2269602B1 (de) 2014-11-19
CN1650863A (zh) 2005-08-10
TR200704370T2 (tr) 2007-11-21
WO2000018386A2 (en) 2000-04-06
HK1038691B (zh) 2004-04-23
DK1384478T3 (da) 2011-05-23
HK1059572A1 (en) 2004-07-09
CA2659064A1 (en) 2000-04-06
TR200100883T2 (tr) 2001-10-22
JP2014144982A (ja) 2014-08-14
DK2796138T3 (en) 2016-12-05
KR20010075138A (ko) 2001-08-09
CY1111404T1 (el) 2015-08-05
JP2012067141A (ja) 2012-04-05
HK1150769A1 (en) 2012-01-13
PT2269602E (pt) 2014-12-29
CA2342211A1 (en) 2000-04-06
TWI222361B (en) 2004-10-21
DE69943287D1 (de) 2011-04-28
BRPI9914151B1 (pt) 2017-10-03
CA2342211C (en) 2009-05-26
PT1117401E (pt) 2004-03-31
CY1115759T1 (el) 2017-01-25
DK2301541T3 (da) 2014-09-01
CY1115916T1 (el) 2017-01-25
ES2526521T3 (es) 2015-01-13

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