DK1007691T3 - Fremgangsmåder og sammensætninger til syntese af langkædede polyumættede fedtsyrer - Google Patents

Fremgangsmåder og sammensætninger til syntese af langkædede polyumættede fedtsyrer

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Publication number
DK1007691T3
DK1007691T3 DK98918175T DK98918175T DK1007691T3 DK 1007691 T3 DK1007691 T3 DK 1007691T3 DK 98918175 T DK98918175 T DK 98918175T DK 98918175 T DK98918175 T DK 98918175T DK 1007691 T3 DK1007691 T3 DK 1007691T3
Authority
DK
Denmark
Prior art keywords
delta5
desaturase
fatty acids
methods
recombinant host
Prior art date
Application number
DK98918175T
Other languages
English (en)
Inventor
Pradip Mukerji
Yung-Sheng Huang
Jennifer Thurmond
Amanda Eun-Yeong Leonard
Deborah Knutzon
Sunita Chaudhary
Original Assignee
Calgene Llc
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calgene Llc, Abbott Lab filed Critical Calgene Llc
Application granted granted Critical
Publication of DK1007691T3 publication Critical patent/DK1007691T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Pediatric Medicine (AREA)
  • Animal Husbandry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
DK98918175T 1997-04-11 1998-04-10 Fremgangsmåder og sammensætninger til syntese af langkædede polyumættede fedtsyrer DK1007691T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/833,610 US5972664A (en) 1997-04-11 1997-04-11 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
PCT/US1998/007422 WO1998046765A1 (en) 1997-04-11 1998-04-10 Methods and compositions for synthesis of long chain polyunsaturated fatty acids
EP98918175A EP1007691B1 (en) 1997-04-11 1998-04-10 Methods and compositions for synthesis of long chain polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
DK1007691T3 true DK1007691T3 (da) 2004-12-20

Family

ID=25264859

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98918175T DK1007691T3 (da) 1997-04-11 1998-04-10 Fremgangsmåder og sammensætninger til syntese af langkædede polyumættede fedtsyrer

Country Status (24)

Country Link
US (2) US5972664A (da)
EP (1) EP1007691B1 (da)
JP (1) JP4453881B2 (da)
KR (2) KR20010006255A (da)
CN (1) CN1253587A (da)
AT (1) ATE277188T1 (da)
AU (1) AU720725B2 (da)
BG (1) BG103796A (da)
BR (1) BR9809083A (da)
CA (1) CA2286263A1 (da)
DE (1) DE69826494T2 (da)
DK (1) DK1007691T3 (da)
ES (1) ES2229491T3 (da)
HU (1) HUP0001295A3 (da)
IL (1) IL132149A0 (da)
IN (1) IN1998KO00639A (da)
NO (1) NO994924L (da)
NZ (1) NZ337458A (da)
PL (1) PL336067A1 (da)
PT (1) PT1007691E (da)
SI (1) SI1007691T1 (da)
SK (1) SK139799A3 (da)
TR (1) TR199902466T2 (da)
WO (1) WO1998046765A1 (da)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6483008B1 (en) * 1990-08-15 2002-11-19 Calgene Llc Methods for producing plants with elevated oleic acid content
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US7745694B1 (en) 1997-04-11 2010-06-29 Monsanto Technology Llc Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US6432684B1 (en) * 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US6428990B1 (en) 1997-04-11 2002-08-06 Abbott Laboratories Human desaturase gene and uses thereof
US20030152983A1 (en) * 1997-12-23 2003-08-14 University Of Bristol Desaturase
EE200000372A (et) * 1997-12-23 2001-12-17 University Of Bristol Desaturaas
CA2329159A1 (en) * 1998-05-29 1999-12-02 Bruce Kelder Compositions and methods for the synthesis of fatty acids, their derivatives and downstream products
US6459018B1 (en) 1998-06-12 2002-10-01 Monsanto Technology Llc Polyunsaturated fatty acids in plants
US6913916B1 (en) 1998-09-02 2005-07-05 Abbott Laboratories Elongase genes and uses thereof
US6677145B2 (en) * 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US20030163845A1 (en) 1998-09-02 2003-08-28 Pradip Mukerji Elongase genes and uses thereof
AU1097900A (en) * 1998-10-05 2000-04-26 Abbott Laboratories Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom
WO2000020603A1 (en) * 1998-10-05 2000-04-13 Abbott Laboratories Altered fatty acid biosynthesis in insect cells using delta five desaturase
US6140081A (en) * 1998-10-16 2000-10-31 The Scripps Research Institute Zinc finger binding domains for GNN
DE10030976A1 (de) 2000-06-30 2002-01-10 Basf Ag DELTA6-Desaturasegene exprimierende Pflanzen und PUFAS enthaltende Öle aus diesen Pflanzen und ein Verfahren zur Herstellung ungesättigter Fettsäuren
WO2001004636A1 (en) * 1999-07-12 2001-01-18 Ohio University Mammalian cells expressing desaturases and elongases
US7070970B2 (en) 1999-08-23 2006-07-04 Abbott Laboratories Elongase genes and uses thereof
EP1254238B1 (de) 2000-02-09 2009-09-16 Basf Se Neues elongasegen und verfahren zur herstellung mehrfach ungesättigter fettsäuren
DE60141760D1 (de) 2000-09-28 2010-05-20 Bioriginal Food & Science Corp Fad4, fad5, fad5-2, and fad6, mitglieder der fettsäuredesaturasefamilie und ihre verwendungen
DE10102337A1 (de) * 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
EP1392823B1 (en) * 2001-01-25 2011-11-30 Abbott Laboratories Desaturase genes and uses thereof
US6635451B2 (en) 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
GB0107510D0 (en) 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
US7179647B2 (en) 2002-01-30 2007-02-20 Basf Plant Science Gmbh Elongase gene and method for producing polyunsaturated fatty acids
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
CA2486559C (en) * 2002-05-22 2015-07-21 Monsanto Technology Llc Fatty acid desaturases from fungi
MXPA05005777A (es) 2002-12-19 2006-03-08 Univ Bristol Metodo novedoso para produccion de acidos grasos poliinsaturados.
US8084074B2 (en) * 2003-02-12 2011-12-27 E. I. Du Pont De Nemours And Company Production of very long chain polyunsaturated fatty acids in oil seed plants
US20040172682A1 (en) * 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
ATE517984T1 (de) 2003-02-27 2011-08-15 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter fettsäuren
AU2004225838B2 (en) 2003-03-31 2009-11-05 University Of Bristol Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids
BRPI0409209A (pt) 2003-04-08 2006-03-28 Basf Plant Science Gmbh seqüência de ácido nucleico isolado, construto de gene, vetor, organismo não-humano transgênico, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeos ou ácidos graxos ou uma fração dos mesmos, composição de óleo, de lipìdeo ou de ácido graxo, e, uso de óleo, de lipìdeos ou de ácidos graxos ou de composição de óleo, de lipìdeo ou de ácido graxo
US7125672B2 (en) * 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
US7238482B2 (en) 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
EP2166090B1 (de) 2003-08-01 2015-07-01 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
PT1656449E (pt) * 2003-08-21 2009-07-27 Monsanto Technology Llc Dessaturases dos ácidos gordos a partir de prímulas
WO2005047480A2 (en) 2003-11-12 2005-05-26 E.I. Dupont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
EP1718663B1 (en) 2004-01-20 2011-07-13 Monsanto Technology, LLC Chimeric promoters for use in plants
CA2558726C (en) 2004-02-27 2017-11-07 Basf Plant Science Gmbh Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms
JP4567047B2 (ja) 2004-02-27 2010-10-20 ビーエーエスエフ プラント サイエンス ゲーエムベーハー トランスジェニック植物における多価不飽和脂肪酸の製造方法
AU2005235081B2 (en) * 2004-04-16 2011-06-16 Monsanto Technology Llc Expression of fatty acid desaturases in corn
DK1756280T3 (da) * 2004-04-22 2015-02-02 Commw Scient Ind Res Org Syntese af langkædede, flerumættede fedtsyrer ved rekombinante celler
CA3023314C (en) 2004-04-22 2019-12-10 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
US20050266051A1 (en) * 2004-05-27 2005-12-01 The Procter & Gamble Company Pet food compositions and methods
ES2351973T3 (es) * 2004-06-04 2011-02-14 Fluxome Sciences A/S Células metabólicamente modificadas por ingeniería para la producción de ácidos grasos poliinsaturados.
CA2568624C (en) 2004-06-25 2014-03-25 E. I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7588931B2 (en) * 2004-11-04 2009-09-15 E. I. Du Pont De Nemours And Company High arachidonic acid producing strains of Yarrowia lipolytica
WO2006092449A2 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
AU2006249983B2 (en) 2005-05-23 2011-03-17 Arcadia Biosciences, Inc. Safflower with elevated gamma-linolenic acid
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
GB2431158A (en) 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
DE102005052551A1 (de) 2005-11-02 2007-05-16 Rothamsted Res Harpenden Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae
KR20080071190A (ko) 2005-11-23 2008-08-01 이 아이 듀폰 디 네모아 앤드 캄파니 델타-９ 일롱가제, 및 다중불포화 지방산 생성에 있어서의이들의 용도
US7723574B2 (en) 2005-11-24 2010-05-25 Basf Plant Science Gmbh Process for the production of Δ5-unsaturated fatty acids in transgenic organisms
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
BRPI0708477B8 (pt) 2006-03-01 2022-12-06 Pioneer Hi Bred Int Método para identificar uma primeira planta de milho ou um primeiro germoplasma de milho compreendendo em seu genoma um gene de diaglicerol o-aciltransferase do tipo 1 (dgat), polinucleotídeo isolado, método para produzir uma planta ou parte de planta possuindo um fenótipo selecionado, método para identificar a presença de um lócus marcador
US8629195B2 (en) 2006-04-08 2014-01-14 Bayer Materialscience Ag Production of polyurethane foams
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
EP2027275A2 (en) 2006-05-16 2009-02-25 Monsanto Technology, LLC Use of non-agrobacterium bacterial species for plant transformation
US7695950B2 (en) * 2006-05-17 2010-04-13 E. I. Du Pont De Nemours And Company Δ5 desaturase and its use in making polyunsaturated fatty acids
US7678560B2 (en) * 2006-05-17 2010-03-16 E.I. Du Pont De Nemours And Company Δ 5 desaturase and its use in making polyunsaturated fatty acids
BRPI0714390B1 (pt) * 2006-07-19 2018-05-15 Monsanto Technology Llc Polinucleotídeo, construção de dna, célula hospedeira fúngica ou bacteriana, processo para produção de alimento ou de produto alimentício e composição para alimento ou produto alimentício
EP2061879A2 (en) 2006-08-24 2009-05-27 BASF Plant Science GmbH Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
AU2007291937B2 (en) 2006-08-29 2014-05-15 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
WO2008040787A2 (de) 2006-10-06 2008-04-10 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen
BRPI0716306A2 (pt) * 2006-10-23 2015-06-16 Du Pont "polinucleotídeo isolado, constructo de dna recombinante célula, yarrowia sp transformada, método para transformar uma célula, método para produzir uma planta transformada, método para produzir leveduras, sementes trangênicas, método para produzir ácidos graxos poli-insaturados de cadeia longa em ima célula, óleo ou subprodutos, método para produzir pelo menos um ácido graxo poli-insaturada em uma célula vegetal oleaginosa, plantas oleaginosas, sementes trangênicas, alimentos ou alimentações e plantas da progênie"
US8389808B2 (en) 2007-02-12 2013-03-05 E.I. Du Pont De Nemours And Company Production of arachidonic acid in oilseed plants
US7838729B2 (en) 2007-02-26 2010-11-23 Monsanto Technology Llc Chloroplast transit peptides for efficient targeting of DMO and uses thereof
BR122017015069B1 (pt) 2007-03-09 2018-07-10 Monsanto Technology Llc Aparelho para geração em alto volume de produção de tecido vegetal transformável
US8188338B2 (en) 2007-04-10 2012-05-29 E. I. Du Pont De Nemours And Company Delta-8 desaturases and their use in making polyunsaturated fatty acids
US7794701B2 (en) 2007-04-16 2010-09-14 E.I. Du Pont De Nemours And Company Δ-9 elongases and their use in making polyunsaturated fatty acids
US8957280B2 (en) * 2007-05-03 2015-02-17 E. I. Du Pont De Nemours And Company Delta-5 desaturases and their use in making polyunsaturated fatty acids
AU2008281760B2 (en) 2007-07-31 2014-07-17 Basf Plant Science Gmbh Elongases and methods for producing polyunsaturated fatty acids in transgenic organisms
WO2009077478A2 (en) 2007-12-14 2009-06-25 Basf Plant Science Gmbh Promoters from brassica napus for seed specific gene expression
CN103333894B (zh) 2008-04-07 2016-11-23 孟山都技术公司 植物调控元件及其应用
AU2009239949A1 (en) * 2008-04-25 2009-10-29 Basf Plant Science Gmbh Plant seed oil
CA2723072C (en) 2008-04-30 2017-01-10 Rothamsted Research Ltd. Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms
US8168858B2 (en) * 2008-06-20 2012-05-01 E. I. Du Pont De Nemours And Company Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids
ES2475973T3 (es) 2008-06-27 2014-07-11 Sapphire Energy, Inc. Inducción de la floculaci�n en organismos fotosint�ticos
WO2010000708A2 (en) 2008-07-01 2010-01-07 Basf Plant Science Gmbh Promoters from brassica napus for seed specific gene expression
WO2010023202A2 (en) 2008-08-26 2010-03-04 Basf Plant Science Gmbh Nucleic acids encoding desaturases and modified plant oil
DK2324119T3 (da) * 2008-09-19 2016-07-18 Du Pont Mutante delta5-desaturaser og anvendelse heraf til fremstilling af polyumættede fedtsyrer
CA3015426C (en) 2008-11-18 2020-01-14 Commonwealth Scientific And Industrial Research Organisation Recombinant cells comprising exogenous .delta.5 and .delta.6 desaturases, .delta.5 and .delta.6 elongases, and .delta.4 desaturases
ES2653727T3 (es) 2008-12-12 2018-02-08 Basf Plant Science Gmbh Desaturasas y proceso para la producción de ácidos grasos poliinsaturados en organismos transgénicos
US8060617B2 (en) * 2008-12-19 2011-11-15 Cisco Technology, Inc. Reserving network resources during scheduling of meeting event
US20120277117A1 (en) 2009-02-27 2012-11-01 Adel Zayed Hydroponic apparatus and methods of use
EP2821492A3 (en) 2009-05-13 2015-04-08 BASF Plant Science Company GmbH Acyltransferases and uses thereof in fatty acid production
WO2011050271A1 (en) 2009-10-23 2011-04-28 Monsanto Technology Llc Methods and compositions for expression of transgenes in plants
CA2786697C (en) 2010-01-14 2018-10-30 Stanislaw Flasinski Plant regulatory elements and uses thereof
US9388437B2 (en) 2010-06-25 2016-07-12 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
CA2807834C (en) 2010-08-26 2019-06-25 E. I. Du Pont De Nemours And Company Recombinant microbial host cells for high eicosapentaenoic acid production
AU2011293189B2 (en) 2010-08-26 2017-02-16 E. I. Du Pont De Nemours And Company Mutant HPGG motif and HDASH motif delta-5 desaturases and their use in making polyunsaturated fatty acids
AR082784A1 (es) 2010-08-30 2013-01-09 Agrigenetics Inc Potenciador viral baciliforme de caña de azucar (scbv) y su uso en la genomica funcional de plantas
BR112013015247B1 (pt) 2010-12-17 2021-11-23 Monsanto Technology Llc Método para melhorar a competência de células de milho para transformação mediada por bactérias
PH12013501978A1 (en) 2011-03-25 2013-11-25 Monsanto Technology Llc Plant regulatory elements and uses thereof
CA2997731C (en) 2011-05-13 2020-05-26 Monsanto Technology Llc Plant regulatory elements and uses thereof
AR090204A1 (es) 2012-02-29 2014-10-29 Dow Agrosciences Llc Potenciador viral baciliforme de caña de azucar (scbv) y su uso en la genomica funcional de plantas
EP2836599B1 (en) 2012-04-12 2019-11-06 Rothamsted Research Limited Production of omega-3 long chain polyunsaturated fatty acids
US9663793B2 (en) 2012-04-20 2017-05-30 Monsanto Technology, Llc Plant regulatory elements and uses thereof
NZ631702A (en) 2012-06-15 2017-01-27 Grains Res & Dev Corp Production of long chain polyunsaturated fatty acids in plant cells
GB201217524D0 (en) 2012-10-01 2012-11-14 Rothamsted Res Ltd Recombinant organisms
KR102281540B1 (ko) 2012-12-19 2021-07-26 몬산토 테크놀로지 엘엘씨 식물 조절 요소 및 그의 용도
MX370800B (es) 2013-03-14 2020-01-07 Monsanto Technology Llc Elementos reguladores de plantas y sus usos.
MX369970B (es) 2013-03-14 2019-11-27 Monsanto Technology Llc Elementos reguladores de plantas y sus usos.
SG10201803827UA (en) 2013-12-04 2018-06-28 Nippon Suisan Kaisha Ltd Microbial oil, production method for microbial oil, concentrated microbial oil, and production method for concentrated microbial oil
EP3082405A4 (en) 2013-12-18 2017-12-13 Commonwealth Scientific and Industrial Research Organisation Lipid comprising long chain polyunsaturated fatty acids
PH12016502586B1 (en) 2014-06-27 2023-07-19 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
ES2885851T5 (en) * 2014-09-30 2025-01-23 Nestle Sa Nutritional composition for use in promoting liver maturation
EP3274462A4 (en) 2015-03-26 2018-12-26 The Texas A&M University System Conversion of lignin into bioplastics and lipid fuels
CA2992488A1 (en) 2015-08-28 2017-03-09 Pioneer Hi-Bred International, Inc. Ochrobactrum-mediated transformation of plants
CN108513583A (zh) 2015-10-02 2018-09-07 孟山都技术公司 重组玉米b染色体序列及其用途
KR20220116067A (ko) 2016-03-11 2022-08-19 몬산토 테크놀로지 엘엘씨 식물 조절 요소 및 이의 용도
CR20180607A (es) 2016-05-24 2019-03-26 Monsanto Technology Llc Elementos reguladores de plantas y sus usos
CA3029271A1 (en) 2016-06-28 2018-01-04 Cellectis Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
WO2018005491A1 (en) 2016-06-28 2018-01-04 Monsanto Technology Llc Methods and compositions for use in genome modification in plants
EP3571305B1 (en) 2017-01-19 2024-05-22 Monsanto Technology LLC Plant regulatory elements and uses thereof
US20200332311A1 (en) 2018-01-12 2020-10-22 The Texas A&M University System Increasing plant bioproduct yield
WO2020243368A1 (en) 2019-05-29 2020-12-03 Monsanto Technology Llc Methods and compositions for generating dominant alleles using genome editing
TW202300650A (zh) 2021-03-26 2023-01-01 美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 真核系統中環狀多核糖核苷酸的產生
EP4314289A1 (en) 2021-03-26 2024-02-07 Flagship Pioneering Innovations VII, LLC Production of circular polyribonucleotides in a prokaryotic system
AR125217A1 (es) 2021-03-26 2023-06-28 Flagship Pioneering Innovations Vii Llc Producción de polirribonucleótidos circulares en un sistema procariota
AU2022375817A1 (en) 2021-11-01 2024-05-09 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
WO2023141540A2 (en) 2022-01-20 2023-07-27 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
CN120265780A (zh) 2022-09-09 2025-07-04 埃朗根-纽伦堡弗里德里希-亚历山大大学 植物调控元件及其用途
WO2024091091A1 (ko) * 2022-10-28 2024-05-02 올케어플러스 주식회사 동물용 영양식 조성물 및 이의 제조 방법
WO2024229359A2 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial tymovirales satellite rnas
WO2024229398A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial amalgavirus satellite rnas
WO2024229385A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial ghabrivirales satellite rnas
WO2024229356A2 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial solemoviridae satellite rnas
AR132591A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de secoviridae artificiales
AR132587A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de martellivirales artificiales
AR132590A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Sistemas de amplificación de arn satélite partitivirales para plantas
AR133211A1 (es) 2023-05-03 2025-09-10 Flagship Pioneering Innovations Vii Llc Arn satélite artificiales de tombusviridae
AR132585A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Sistemas de amplificación de arn satélite endornavirales para plantas
US20250075226A1 (en) 2023-08-29 2025-03-06 University Of Freiburg Proteins for regulation of symbiotic infection and associated regulatory elements

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3649295A (en) * 1970-06-01 1972-03-14 American Home Prod Humanized fat compositions and infant formulas thereof
US4058594A (en) * 1974-04-25 1977-11-15 John Williams Immuno-suppressive agents
ATE24266T1 (de) * 1982-04-16 1987-01-15 Nestle Sa Lipidhaltige zusammensetzung fuer die orale, enterale oder parenterale ernaehrung.
US4670285A (en) * 1982-08-06 1987-06-02 The University Of Toronto Innovations Foundation Infant formula
GB8317248D0 (en) * 1983-06-24 1983-07-27 Wyeth John & Brother Ltd Fat compositions
US4526902A (en) * 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
US4920098A (en) * 1986-09-17 1990-04-24 Baxter International Inc. Nutritional support or therapy for individuals at risk or under treatment for atherosclerotic vascular, cardiovascular, and/or thrombotic diseases
US4843095A (en) * 1987-08-07 1989-06-27 Century Laboratories, Inc. Free fatty acids for treatment or propyhlaxis of rheumatoid arthritis arthritis
US5057419A (en) * 1988-09-22 1991-10-15 Rutgers University Genetically engineered plasmid and organisms for the production of specialized oils
US5407957A (en) * 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US5512482A (en) * 1990-04-26 1996-04-30 Calgene, Inc. Plant thioesterases
DK0537178T4 (da) * 1990-05-25 2007-07-16 Du Pont Nukleotidsekvens af sojabönne-stearoyl-ACP-desaturase-gen
SG49307A1 (en) * 1991-01-24 1998-05-18 Martek Corp Microbial oil mixtures and use thereof
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
JPH0591886A (ja) * 1991-09-30 1993-04-16 Suntory Ltd ８，１１−エイコサジエン酸及びこれを含有する脂質の製造方法
PH31293A (en) * 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US5614393A (en) * 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
ES2201054T3 (es) * 1992-03-13 2004-03-16 Agrigenetics, Inc. Modificacion de aceites vegetales usando desaturasa.
CA2149223C (en) 1992-11-17 2007-04-24 Jonathan Edward Lightner Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
CA2150133A1 (en) * 1993-02-05 1994-08-18 Vincent Jean-Marie Armel Arondel Altered linolenic and linoleic acid content in plants
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US5654402A (en) * 1994-10-26 1997-08-05 Michigan State University Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase

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