AR053477A1 - Cartamo con acido gamma - linolenico elevado - Google Patents
Cartamo con acido gamma - linolenico elevadoInfo
- Publication number
- AR053477A1 AR053477A1 ARP060102090A ARP060102090A AR053477A1 AR 053477 A1 AR053477 A1 AR 053477A1 AR P060102090 A ARP060102090 A AR P060102090A AR P060102090 A ARP060102090 A AR P060102090A AR 053477 A1 AR053477 A1 AR 053477A1
- Authority
- AR
- Argentina
- Prior art keywords
- seeds
- safflower
- gla
- sequences
- linolenic
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
Abstract
La presente se refiere a composiciones y métodos para preparar ácido gamma-linoleico (GLA) en plantas de cártamo, particularmente de semillas de cártamo. Las secuencias de ácidos nucleicos y construcciones que codifican una o más secuencias de desaturasas de ácidos grasos se utilizan para generar plantas de cártamo transgénicas que contienen y expresan una o más de estas secuencias y producen altos niveles de GLA en semillas de cártamo. Se proporcionan plantas de cártamo transgénicas y semillas que producen altos niveles de GLA. Se proporcionan además aceites producidos de semillas de la presente. La presente también se refiere a métodos de tratamiento de una variedad de enfermedades incluyendo trastornos del sistema nervioso, afecciones inflamatorias, cáncer y trastornos cardiovasculares utilizando los aceites de la presente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68413405P | 2005-05-23 | 2005-05-23 | |
US73598405P | 2005-11-10 | 2005-11-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR053477A1 true AR053477A1 (es) | 2007-05-09 |
Family
ID=37452775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060102090A AR053477A1 (es) | 2005-05-23 | 2006-05-22 | Cartamo con acido gamma - linolenico elevado |
Country Status (13)
Country | Link |
---|---|
US (2) | US7893321B2 (es) |
EP (1) | EP1885862B1 (es) |
JP (1) | JP5033122B2 (es) |
CN (1) | CN101321872B (es) |
AR (1) | AR053477A1 (es) |
AU (1) | AU2006249983B2 (es) |
BR (1) | BRPI0611480B1 (es) |
CA (1) | CA2609367C (es) |
CL (1) | CL2007003413A1 (es) |
ES (1) | ES2550623T3 (es) |
HK (1) | HK1120823A1 (es) |
NZ (1) | NZ563676A (es) |
WO (1) | WO2006127789A2 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0519724A2 (pt) * | 2004-12-20 | 2009-01-20 | Basf Plant Science Gmbh | polipeptÍdeo isolado, seqÜÊncia de Ácido nucleico isolada, Ácido nucleico isolado, vetor de expressço, mÉtodos de produzir uma planta transgÊnica e de modular o nÍvel de uma porcentagem em peso de composto de armazenagem de semente em uma planta, planta transgÊncia, e, semente |
CN101516181B (zh) | 2006-07-14 | 2015-09-30 | 联邦科学技术研究组织 | 改变水稻的脂肪酸组成 |
EP2271223A2 (de) * | 2008-04-25 | 2011-01-12 | BASF Plant Science GmbH | Pflanzensamenöl |
US8148121B2 (en) * | 2008-08-01 | 2012-04-03 | E.I. Du Pont De Nemours And Company | Δ6 desaturases and their use in making polyunsaturated fatty acids |
NZ631696A (en) * | 2012-04-25 | 2017-02-24 | Grains Res & Dev Corp | High oleic acid oils |
PL2861059T3 (pl) | 2012-06-15 | 2017-10-31 | Commw Scient Ind Res Org | Wytwarzanie długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach roślinnych |
CA2932654A1 (en) | 2013-12-10 | 2015-06-18 | The University Of York | Desaturase nucleic acids and polypeptides |
NZ721036A (en) | 2013-12-18 | 2023-07-28 | Grains Res & Dev Corp | Lipid comprising long chain polyunsaturated fatty acids |
SG11201610596PA (en) | 2014-06-27 | 2017-01-27 | Commw Scient Ind Res Org | Lipid comprising docosapentaenoic acid |
Family Cites Families (44)
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US5034322A (en) | 1983-01-17 | 1991-07-23 | Monsanto Company | Chimeric genes suitable for expression in plant cells |
US4743548A (en) | 1984-09-25 | 1988-05-10 | Calgene, Inc. | Plant cell microinjection technique |
US5420034A (en) | 1986-07-31 | 1995-05-30 | Calgene, Inc. | Seed-specific transcriptional regulation |
US4943674A (en) | 1987-05-26 | 1990-07-24 | Calgene, Inc. | Fruit specific transcriptional factors |
US5068193A (en) | 1985-11-06 | 1991-11-26 | Calgene, Inc. | Novel method and compositions for introducing alien DNA in vivo |
US4795855A (en) | 1985-11-14 | 1989-01-03 | Joanne Fillatti | Transformation and foreign gene expression with woody species |
US5188958A (en) | 1986-05-29 | 1993-02-23 | Calgene, Inc. | Transformation and foreign gene expression in brassica species |
US5565347A (en) | 1986-06-10 | 1996-10-15 | Calgene, Inc. | Transformation and foreign gene expression with plant species |
DE3856589D1 (de) | 1987-10-20 | 2006-04-06 | Bayer Bioscience Nv | 5'-flankierende Region eines Genes von Arabidopsis, das für einen 2S Albumin-Prekursor kodiert |
US5614395A (en) | 1988-03-08 | 1997-03-25 | Ciba-Geigy Corporation | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof |
US5565346A (en) | 1988-07-27 | 1996-10-15 | Calgene, Inc. | Transformation and regeneration system for legumes |
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US5175095A (en) | 1989-07-19 | 1992-12-29 | Calgene, Inc. | Ovary-tissue transcriptional factors |
ES2033193B1 (es) | 1990-10-30 | 1994-01-16 | Ganadera Union Ind Agro | Mezcla grasa para nutricion infantil y de adultos. |
US6355861B1 (en) | 1991-10-10 | 2002-03-12 | Rhone-Poulenc Agrochimie | Production of gamma linolenic acid by a Δ6-desaturase |
US5614393A (en) | 1991-10-10 | 1997-03-25 | Rhone-Poulenc Agrochimie | Production of γ-linolenic acid by a Δ6-desaturase |
PH31293A (en) | 1991-10-10 | 1998-07-06 | Rhone Poulenc Agrochimie | Production of y-linolenic acid by a delta6-desaturage. |
ES2187505T3 (es) | 1992-04-02 | 2003-06-16 | Sembiosys Genetics Inc | Elementos cis de proteinas de cuerpo oleoso como señales reguladoras. |
US5539092A (en) | 1992-10-02 | 1996-07-23 | Arch Development Corporation | Cyanobacterial and plant acetyl-CoA carboxylase |
JPH08509860A (ja) | 1993-02-26 | 1996-10-22 | カルジーン インコーポレイティド | ジェミニウィルスを基礎とする遺伝子発現系 |
US6432684B1 (en) | 1997-04-11 | 2002-08-13 | Abbott Laboratories | Human desaturase gene and uses thereof |
IL132148A0 (en) | 1997-04-11 | 2001-03-19 | Calgene Llc | Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants |
US6051754A (en) | 1997-04-11 | 2000-04-18 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
US6075183A (en) | 1997-04-11 | 2000-06-13 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
US5968809A (en) | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
US5972664A (en) | 1997-04-11 | 1999-10-26 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
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EP1019517B2 (en) | 1997-09-30 | 2014-05-21 | The Regents of The University of California | Production of proteins in plant seeds |
US6653530B1 (en) * | 1998-02-13 | 2003-11-25 | Calgene Llc | Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds |
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KR20020073580A (ko) * | 2000-02-09 | 2002-09-27 | 바스프 악티엔게젤샤프트 | 신규 연장효소 유전자 및 다가불포화 지방산의 제조 방법 |
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BR0205508A (pt) | 2001-01-25 | 2005-05-03 | Abbott Lab | Genes para dessaturase e usos dos mesmos |
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PT1440151E (pt) * | 2001-09-05 | 2008-03-17 | Monsanto Technology Llc | Promotor 7s alfa específico da semente para expressar genes em plantas |
BRPI0411479A (pt) | 2003-06-17 | 2006-07-25 | Sembiosys Genetics Inc | métodos para a produção de insulina em plantas |
JP5031366B2 (ja) * | 2003-08-01 | 2012-09-19 | ビーエーエスエフ プラント サイエンス ゲーエムベーハー | トランスジェニック生物における多不飽和脂肪酸の製造方法 |
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2006
- 2006-05-22 CN CN2006800243596A patent/CN101321872B/zh active Active
- 2006-05-22 NZ NZ563676A patent/NZ563676A/en unknown
- 2006-05-22 CA CA2609367A patent/CA2609367C/en active Active
- 2006-05-22 WO PCT/US2006/020047 patent/WO2006127789A2/en active Application Filing
- 2006-05-22 EP EP06771043.4A patent/EP1885862B1/en active Active
- 2006-05-22 AR ARP060102090A patent/AR053477A1/es active IP Right Grant
- 2006-05-22 US US11/438,951 patent/US7893321B2/en active Active
- 2006-05-22 AU AU2006249983A patent/AU2006249983B2/en active Active
- 2006-05-22 JP JP2008513656A patent/JP5033122B2/ja active Active
- 2006-05-22 ES ES06771043.4T patent/ES2550623T3/es active Active
- 2006-05-22 BR BRPI0611480A patent/BRPI0611480B1/pt active IP Right Grant
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2007
- 2007-11-28 CL CL200703413A patent/CL2007003413A1/es unknown
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2008
- 2008-08-13 HK HK08108949.7A patent/HK1120823A1/xx unknown
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2011
- 2011-02-11 US US13/025,345 patent/US8192964B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2006127789A3 (en) | 2007-11-29 |
CA2609367A1 (en) | 2006-11-30 |
WO2006127789A2 (en) | 2006-11-30 |
CL2007003413A1 (es) | 2008-07-25 |
EP1885862A4 (en) | 2009-02-25 |
EP1885862B1 (en) | 2015-07-29 |
US8192964B2 (en) | 2012-06-05 |
AU2006249983A1 (en) | 2006-11-30 |
CN101321872B (zh) | 2012-09-05 |
BRPI0611480B1 (pt) | 2016-06-07 |
ES2550623T3 (es) | 2015-11-11 |
WO2006127789A9 (en) | 2012-03-01 |
CN101321872A (zh) | 2008-12-10 |
US20110129428A1 (en) | 2011-06-02 |
HK1120823A1 (en) | 2009-04-09 |
JP2008545411A (ja) | 2008-12-18 |
JP5033122B2 (ja) | 2012-09-26 |
EP1885862A2 (en) | 2008-02-13 |
NZ563676A (en) | 2011-01-28 |
US20070067870A1 (en) | 2007-03-22 |
US7893321B2 (en) | 2011-02-22 |
BRPI0611480A2 (pt) | 2010-09-14 |
AU2006249983B2 (en) | 2011-03-17 |
CA2609367C (en) | 2014-08-19 |
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