DK0999826T3 - Selv-emulgerende formulering til lipofile forbindelser - Google Patents
Selv-emulgerende formulering til lipofile forbindelserInfo
- Publication number
- DK0999826T3 DK0999826T3 DK98936889T DK98936889T DK0999826T3 DK 0999826 T3 DK0999826 T3 DK 0999826T3 DK 98936889 T DK98936889 T DK 98936889T DK 98936889 T DK98936889 T DK 98936889T DK 0999826 T3 DK0999826 T3 DK 0999826T3
- Authority
- DK
- Denmark
- Prior art keywords
- diglyceride
- monoglyceride
- self
- emulsifying formulation
- lipophilic compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5407897P | 1997-07-29 | 1997-07-29 | |
US5401297P | 1997-07-29 | 1997-07-29 | |
PCT/US1998/014818 WO1999006024A1 (en) | 1997-07-29 | 1998-07-27 | Self-emulsifying formulation for lipophilic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0999826T3 true DK0999826T3 (da) | 2004-07-26 |
Family
ID=26732506
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98936889T DK0999826T3 (da) | 1997-07-29 | 1998-07-27 | Selv-emulgerende formulering til lipofile forbindelser |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0999826B1 (ja) |
JP (2) | JP2002511099A (ja) |
KR (1) | KR100509776B1 (ja) |
CN (1) | CN1208047C (ja) |
AT (1) | ATE265847T1 (ja) |
AU (1) | AU728698B2 (ja) |
BR (1) | BR9811058A (ja) |
CA (1) | CA2294031E (ja) |
CZ (1) | CZ297206B6 (ja) |
DE (1) | DE69823663T2 (ja) |
DK (1) | DK0999826T3 (ja) |
ES (1) | ES2219895T3 (ja) |
FI (1) | FI20000170A (ja) |
HK (1) | HK1028883A1 (ja) |
HU (1) | HU226114B1 (ja) |
NO (1) | NO328591B1 (ja) |
NZ (1) | NZ502569A (ja) |
PL (1) | PL191780B1 (ja) |
PT (1) | PT999826E (ja) |
RU (1) | RU2211021C2 (ja) |
SI (1) | SI0999826T1 (ja) |
SK (1) | SK284511B6 (ja) |
WO (1) | WO1999006024A1 (ja) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6964946B1 (en) * | 1995-10-26 | 2005-11-15 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
RU2203648C2 (ru) * | 1997-07-29 | 2003-05-10 | Фармация Энд Апджон Компани | Самоэмульгирующаяся композиция для липофильных соединений |
US5922754A (en) * | 1998-10-02 | 1999-07-13 | Abbott Laboratories | Pharmaceutical compositions containing paclitaxel |
US6040330A (en) * | 1999-01-08 | 2000-03-21 | Bionumerik Pharmaceuticals, Inc. | Pharmaceutical formulations of taxanes |
GB9903547D0 (en) | 1999-02-16 | 1999-04-07 | Novartis Ag | Organic compounds |
US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
DE19912436A1 (de) * | 1999-03-19 | 2000-09-21 | Merckle Gmbh | Ibuprofen-Lösung |
US6652880B1 (en) | 1999-04-01 | 2003-11-25 | R.P. Scherer Technologies, Inc. | Oral pharmaceutical compositions containing long-chain triglycerides and liphophilic surfactants |
EP1479382A1 (en) * | 1999-06-18 | 2004-11-24 | IVAX Research, Inc. | Oral pharmaceutical compositions containing taxanes and methods for treatment employing the same |
GB2355656B (en) * | 1999-08-17 | 2004-04-07 | Galena As | Pharmaceutical compositions for oral and topical administration |
GB0001928D0 (en) * | 2000-01-27 | 2000-03-22 | Novartis Ag | Organic compounds |
KR20010100194A (ko) * | 2000-03-13 | 2001-11-14 | 박호군 | 여러 가지 물질의 가용화용 조성물과 제형 및 그들의제조방법 |
US6610272B1 (en) * | 2000-05-01 | 2003-08-26 | Aeropharm Technology Incorporated | Medicinal aerosol formulation |
US7115565B2 (en) | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
KR100425755B1 (ko) * | 2001-08-27 | 2004-04-03 | 주식회사 원진신약 | 이트라코나졸을 함유하는 조성물 및 그 제조방법 |
ES2283756T3 (es) * | 2002-03-01 | 2007-11-01 | Novagali Pharma Sa | Sistemas autoemulsionantes de administracion de farmaco para taxoides. |
EP1340497A1 (en) * | 2002-03-01 | 2003-09-03 | Novagali Sas | Self emulsifying drug delivery systems for poorly soluble drugs |
KR100573289B1 (ko) * | 2002-07-20 | 2006-04-24 | 대화제약 주식회사 | 방광내 투여를 통한 방광암치료용 파클리탁셀 조성물 및그의 제조 방법 |
KR100533458B1 (ko) | 2002-07-20 | 2005-12-07 | 대화제약 주식회사 | 파클리탁셀의 가용화용 조성물 및 그의 제조 방법 |
US20040185068A1 (en) * | 2003-03-18 | 2004-09-23 | Zhi-Jian Yu | Self-emulsifying compositions, methods of use and preparation |
JP2006521366A (ja) * | 2003-03-28 | 2006-09-21 | シグモイド・バイオテクノロジーズ・リミテッド | シームレスマイクロカプセルを含む固形経口剤形 |
GT200500310A (es) | 2004-11-19 | 2006-06-19 | Compuestos organicos | |
ITRM20050418A1 (it) * | 2005-08-04 | 2007-02-05 | Sigma Tau Ind Farmaceuti | Sistemi terapeutici a rilascio immediato per il migliorato assorbimento orale di 7-[(e)-t-butilossimminometil] camptotecina. |
JP2010523555A (ja) | 2007-04-04 | 2010-07-15 | シグモイド・ファーマ・リミテッド | 「経口医薬組成物」 |
EP2061587A1 (en) | 2007-04-26 | 2009-05-27 | Sigmoid Pharma Limited | Manufacture of multiple minicapsules |
SI2868315T1 (sl) | 2007-12-04 | 2017-10-30 | Biogen Chesapeake Llc | Izboljšane formulacije in metode za liofilizacijo in liofilizate zagotovljene z le-to |
US20110034560A1 (en) * | 2008-01-29 | 2011-02-10 | Sven Jacobson | Liquid formulations of compounds active at sulfonylurea receptors |
EP2307003A2 (en) * | 2008-05-16 | 2011-04-13 | Pharma Mar S.A. | Combination therapy with pm00104 and another antitumor agent |
EP2204167A1 (en) * | 2009-01-05 | 2010-07-07 | Azad Pharma AG | Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules |
SG176145A1 (en) | 2009-05-18 | 2011-12-29 | Sigmoid Pharma Ltd | Composition comprising oil drops |
DK2451438T3 (da) * | 2009-07-07 | 2014-03-10 | Boehringer Ingelheim Int | Farmaceutisk sammensætning til en hepatitis C-virus-roteaseinhibitor |
JP5911799B2 (ja) | 2009-08-12 | 2016-04-27 | シグモイド・ファーマ・リミテッドSigmoid Pharma Limited | ポリマーマトリックスおよび油相を含んで成る免疫調節組成物 |
US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
US9119772B2 (en) * | 2011-01-26 | 2015-09-01 | Allergan, Inc. | Androgen composition for treating an opthalmic condition |
GB2488788B (en) | 2011-03-07 | 2013-07-10 | Natco Pharma Ltd | Oral formulation of phenylaminopyrymidine compound with enhanced bioavailability and pharmacological response |
AU2012229997B2 (en) | 2011-03-15 | 2016-04-14 | Lawrence Livermore National Security, Llc | Tricyclic gyrase inhibitors |
GB201212010D0 (en) * | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
MX2015009045A (es) * | 2013-01-14 | 2015-12-17 | Infirst Healthcare Ltd | Composiciones y metodos para tratar el dolor severo. |
EP3858335A1 (en) * | 2013-01-14 | 2021-08-04 | InFirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
CA2898017A1 (en) * | 2013-02-04 | 2014-08-07 | Infirst Healthcare Limited | Compositions and methods for treating chronic inflammation and inflammatory diseases |
TWI729969B (zh) * | 2013-08-29 | 2021-06-11 | 美商亞培公司 | 具有改良溶解度及生物可利用性之含有親脂性化合物之營養組合物 |
GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
CN104706591B (zh) * | 2013-12-16 | 2018-09-04 | 天津迈迪瑞康生物医药科技有限公司 | 一种前列地尔药物组合物、其制备方法及用途 |
KR102537085B1 (ko) * | 2014-01-17 | 2023-05-25 | 옹코랄 파르마 에이피에스 | 암의 치료를 위한 이리노테칸의 고형 경구 투여형 |
KR20170020779A (ko) | 2014-06-17 | 2017-02-24 | 머크 샤프 앤 도메 비.브이. | 테스토스테론 운데카노에이트의 안정한 제제 |
CN104274532A (zh) * | 2014-10-21 | 2015-01-14 | 河南牧翔动物药业有限公司 | 复方灰黄霉素抗菌药物 |
AU2015341695B2 (en) | 2014-11-07 | 2021-07-08 | Sublimity Therapeutics Limited | Compositions comprising cyclosporin |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
KR101587385B1 (ko) * | 2015-07-29 | 2016-01-21 | 국제약품공업주식회사 | 사이클로스포린 함유 무자극성의 안약조성물 및 편리한 제조방법 |
CN108024914A (zh) | 2015-09-17 | 2018-05-11 | Jrx生物技术有限公司 | 改善皮肤的水合作用或润湿作用的方法 |
JP2019513709A (ja) | 2016-04-01 | 2019-05-30 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | ステロイドホルモン薬学的組成物 |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
Family Cites Families (15)
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GB981926A (en) * | 1963-01-22 | 1965-01-27 | Wm Stewart & Arnold Ltd | Method of preparing liquid and dried egg |
DE2556592C2 (de) * | 1975-12-16 | 1986-10-09 | A. Nattermann & Cie GmbH, 5000 Köln | Arzneimittelzubereitungen auf Basis öliger Lösungen von Phospholipiden |
US4338307A (en) * | 1980-11-10 | 1982-07-06 | Abbott Laboratories | 2'-N-Des-β-lysyl antibiotic AX-127B-1 and 4-N-acyl and alkyl derivatives thereof |
DE3629386A1 (de) * | 1986-08-29 | 1988-03-03 | Scherer Gmbh R P | Gelatinekapseln und verfahren zu ihrer herstellung |
DE3779999T2 (de) * | 1986-11-14 | 1992-12-10 | Theratech Inc | Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems. |
CA2038744C (en) * | 1990-03-23 | 2002-01-08 | Yoshitomi Pharmaceutical Industries Ltd. | Pharmaceutical composition containing slightly water-soluble drug |
GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
JPH0734724B2 (ja) * | 1992-02-03 | 1995-04-19 | 日清製油株式会社 | 抱水性クリーム状組成物 |
GB9208712D0 (en) * | 1992-04-22 | 1992-06-10 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporin derivates |
EP0589843B1 (en) * | 1992-09-25 | 2001-11-28 | Novartis AG | Pharmaceutical compositions containing cyclosporins |
IL129871A (en) * | 1994-05-06 | 2003-11-23 | Pharmacia & Upjohn Inc | Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections |
WO1996036316A1 (en) * | 1995-05-19 | 1996-11-21 | Abbott Laboratories | Self-emulsifying formulations of lipophilic drugs |
DE19537012A1 (de) * | 1995-10-04 | 1997-04-10 | Dietl Hans | Cyclosporin(e) enhaltende pharmazeutische Zubereitung zur oralen Applikation und Verfahren zu ihrer Herstellung |
ZA9710071B (en) * | 1996-11-21 | 1998-05-25 | Abbott Lab | Pharmaceutical composition. |
RU2203648C2 (ru) * | 1997-07-29 | 2003-05-10 | Фармация Энд Апджон Компани | Самоэмульгирующаяся композиция для липофильных соединений |
-
1998
- 1998-07-27 CZ CZ20000157A patent/CZ297206B6/cs not_active IP Right Cessation
- 1998-07-27 CA CA2294031A patent/CA2294031E/en not_active Expired - Fee Related
- 1998-07-27 EP EP98936889A patent/EP0999826B1/en not_active Expired - Lifetime
- 1998-07-27 DK DK98936889T patent/DK0999826T3/da active
- 1998-07-27 JP JP51097499A patent/JP2002511099A/ja not_active Withdrawn
- 1998-07-27 PT PT98936889T patent/PT999826E/pt unknown
- 1998-07-27 NZ NZ502569A patent/NZ502569A/en not_active IP Right Cessation
- 1998-07-27 DE DE69823663T patent/DE69823663T2/de not_active Expired - Lifetime
- 1998-07-27 SI SI9830666T patent/SI0999826T1/xx unknown
- 1998-07-27 KR KR10-2000-7000944A patent/KR100509776B1/ko not_active IP Right Cessation
- 1998-07-27 AT AT98936889T patent/ATE265847T1/de active
- 1998-07-27 RU RU2000104856/14A patent/RU2211021C2/ru not_active IP Right Cessation
- 1998-07-27 BR BR9811058-6A patent/BR9811058A/pt not_active Application Discontinuation
- 1998-07-27 WO PCT/US1998/014818 patent/WO1999006024A1/en active IP Right Grant
- 1998-07-27 HU HU0002486A patent/HU226114B1/hu not_active IP Right Cessation
- 1998-07-27 AU AU85739/98A patent/AU728698B2/en not_active Ceased
- 1998-07-27 CN CNB988067706A patent/CN1208047C/zh not_active Expired - Fee Related
- 1998-07-27 SK SK17-2000A patent/SK284511B6/sk not_active IP Right Cessation
- 1998-07-27 PL PL338509A patent/PL191780B1/pl unknown
- 1998-07-27 ES ES98936889T patent/ES2219895T3/es not_active Expired - Lifetime
-
2000
- 2000-01-28 NO NO20000467A patent/NO328591B1/no not_active IP Right Cessation
- 2000-01-28 FI FI20000170A patent/FI20000170A/fi not_active IP Right Cessation
- 2000-12-21 HK HK00108299A patent/HK1028883A1/xx not_active IP Right Cessation
-
2009
- 2009-12-24 JP JP2009291821A patent/JP5227301B2/ja not_active Expired - Fee Related
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