DK0998486T4 - Proteinoprensning ved kromatografi efterfulgt af filtrering på en ladet fase - Google Patents

Proteinoprensning ved kromatografi efterfulgt af filtrering på en ladet fase

Info

Publication number
DK0998486T4
DK0998486T4 DK98926586.3T DK98926586T DK0998486T4 DK 0998486 T4 DK0998486 T4 DK 0998486T4 DK 98926586 T DK98926586 T DK 98926586T DK 0998486 T4 DK0998486 T4 DK 0998486T4
Authority
DK
Denmark
Prior art keywords
filtration
protein purification
chromatography followed
composition
reagent
Prior art date
Application number
DK98926586.3T
Other languages
English (en)
Other versions
DK0998486T3 (da
Inventor
Gerardo A Zapata
Gregory S Blank
Daljit S Narindray
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21968517&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0998486(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DK0998486T3 publication Critical patent/DK0998486T3/da
Application granted granted Critical
Publication of DK0998486T4 publication Critical patent/DK0998486T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK98926586.3T 1997-06-13 1998-06-12 Proteinoprensning ved kromatografi efterfulgt af filtrering på en ladet fase DK0998486T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5095197P 1997-06-13 1997-06-13
PCT/US1998/012334 WO1998056808A1 (en) 1997-06-13 1998-06-12 Protein recovery by chromatography followed by filtration upon a charged layer

Publications (2)

Publication Number Publication Date
DK0998486T3 DK0998486T3 (da) 2007-09-10
DK0998486T4 true DK0998486T4 (da) 2012-05-14

Family

ID=21968517

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98926586.3T DK0998486T4 (da) 1997-06-13 1998-06-12 Proteinoprensning ved kromatografi efterfulgt af filtrering på en ladet fase

Country Status (12)

Country Link
US (4) US6121428A (da)
EP (1) EP0998486B2 (da)
JP (1) JP2001510483A (da)
AT (1) ATE361930T1 (da)
AU (1) AU735883C (da)
CA (1) CA2289665C (da)
DE (1) DE69837760T3 (da)
DK (1) DK0998486T4 (da)
ES (1) ES2287976T3 (da)
IL (1) IL132838A (da)
PT (1) PT998486E (da)
WO (1) WO1998056808A1 (da)

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JP2001510483A (ja) * 1997-06-13 2001-07-31 ジェネンテク，インコーポレイテッド タンパク質の回収
ES2307585T3 (es) * 2000-02-22 2008-12-01 Laboratoires Serono Sa Procedimiento para purificar hcg recombinante que tiene una bioactividad especifica.
US7160541B2 (en) 2000-09-01 2007-01-09 The Center For Blood Research, Inc. Modified polypeptides stabilized in a desired conformation and methods for producing same
WO2002060377A2 (en) * 2000-12-15 2002-08-08 The Johns Hopkins University The separation, identification and quantitation of protein mixtures
US20040067599A1 (en) * 2001-12-14 2004-04-08 Katz Joseph L. Separation identification and quantitation of protein mixtures
MXPA04006053A (es) * 2001-12-21 2005-03-31 Immunex Corp Metodos para purificacion de proteina.
WO2008121719A1 (en) * 2007-03-30 2008-10-09 The Cleveland Clinic Foundation Method of treating ischemic disorders
US20050271639A1 (en) * 2002-08-22 2005-12-08 Penn Marc S Genetically engineered cells for therapeutic applications
HUE027196T2 (hu) 2002-09-06 2016-10-28 Genentech Inc Eljárás fehérjeextrakcióra
DK1581644T3 (da) 2003-01-09 2007-10-08 Genentech Inc Oprensning af polypeptider
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
CN100526453C (zh) * 2005-05-20 2009-08-12 麦克奥迪实业集团有限公司 激光显微切割后细胞收集方法
US7794970B2 (en) 2005-09-20 2010-09-14 Amgen Inc. Method for generating F(ab′)2 antibody fragments
EP1963367A4 (en) * 2005-12-06 2009-05-13 Amgen Inc POLISHING STEPS IN MULTI-STAGE PROTEIN PURIFICATION TREATMENTS
US8163886B2 (en) 2006-12-21 2012-04-24 Emd Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
JP5064558B2 (ja) 2007-06-01 2012-10-31 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリン精製
AU2008338525B2 (en) 2007-12-14 2015-04-02 Juventas Therapeutics, Inc. Compositions and methods of promoting wound healing
EP2370561B1 (en) 2008-12-16 2019-08-07 EMD Millipore Corporation Stirred tank reactor and method
JP2012513425A (ja) 2008-12-22 2012-06-14 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリンの精製
AU2010286511B2 (en) 2009-08-28 2016-05-26 Juventas Therapeutics, Inc. SDF-1 delivery for treating ischemic tissue
ES2526876T3 (es) * 2009-09-10 2015-01-16 Lonza Biologics Plc. Método y sistema para purificación de polipéptidos
US8691918B2 (en) 2010-05-17 2014-04-08 Emd Millipore Corporation Stimulus responsive polymers for the purification of biomolecules
BR112014012539B1 (pt) 2011-11-23 2022-12-20 Medimmune, Llc Anticorpo que se liga especificamente a her3, composição compreendendo o mesmo, e usos do anticorpo
US11305012B2 (en) 2013-09-24 2022-04-19 Medimmune, Llc Binding molecules specific for HER3 and uses thereof
WO2015157634A1 (en) 2014-04-11 2015-10-15 Kolltan Pharmaceuticals, Inc. Anti-erbb antibodies and methods of use thereof

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JP2001510483A (ja) * 1997-06-13 2001-07-31 ジェネンテク，インコーポレイテッド タンパク質の回収

Also Published As

Publication number Publication date
IL132838A0 (en) 2001-03-19
EP0998486A1 (en) 2000-05-10
WO1998056808A1 (en) 1998-12-17
DE69837760T3 (de) 2012-06-21
DK0998486T3 (da) 2007-09-10
AU735883B2 (en) 2001-07-19
US20020058324A1 (en) 2002-05-16
JP2001510483A (ja) 2001-07-31
ES2287976T3 (es) 2007-12-16
PT998486E (pt) 2007-08-21
US6716598B2 (en) 2004-04-06
DE69837760D1 (de) 2007-06-21
CA2289665C (en) 2005-08-09
DE69837760T2 (de) 2008-02-28
US6121428A (en) 2000-09-19
US20040138426A1 (en) 2004-07-15
EP0998486B2 (en) 2012-02-01
IL132838A (en) 2004-08-31
US6322997B1 (en) 2001-11-27
EP0998486B1 (en) 2007-05-09
AU7838898A (en) 1998-12-30
CA2289665A1 (en) 1998-12-17
ATE361930T1 (de) 2007-06-15
AU735883C (en) 2002-02-07

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