ATE361930T1 - Proteinreinigung mittels chromatographie und darauffolgende filtration auf beladener schicht - Google Patents

Proteinreinigung mittels chromatographie und darauffolgende filtration auf beladener schicht

Info

Publication number
ATE361930T1
ATE361930T1 AT98926586T AT98926586T ATE361930T1 AT E361930 T1 ATE361930 T1 AT E361930T1 AT 98926586 T AT98926586 T AT 98926586T AT 98926586 T AT98926586 T AT 98926586T AT E361930 T1 ATE361930 T1 AT E361930T1
Authority
AT
Austria
Prior art keywords
chromatography
protein purification
subsequent filtration
loaded layer
composition
Prior art date
Application number
AT98926586T
Other languages
English (en)
Inventor
Gregory Blank
Daljit Narindray
Gerardo Zapata
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21968517&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE361930(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE361930T1 publication Critical patent/ATE361930T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98926586T 1997-06-13 1998-06-12 Proteinreinigung mittels chromatographie und darauffolgende filtration auf beladener schicht ATE361930T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5095197P 1997-06-13 1997-06-13

Publications (1)

Publication Number Publication Date
ATE361930T1 true ATE361930T1 (de) 2007-06-15

Family

ID=21968517

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98926586T ATE361930T1 (de) 1997-06-13 1998-06-12 Proteinreinigung mittels chromatographie und darauffolgende filtration auf beladener schicht

Country Status (12)

Country Link
US (4) US6121428A (de)
EP (1) EP0998486B2 (de)
JP (1) JP2001510483A (de)
AT (1) ATE361930T1 (de)
AU (1) AU735883C (de)
CA (1) CA2289665C (de)
DE (1) DE69837760T3 (de)
DK (1) DK0998486T4 (de)
ES (1) ES2287976T3 (de)
IL (1) IL132838A (de)
PT (1) PT998486E (de)
WO (1) WO1998056808A1 (de)

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US7297777B2 (en) * 2000-02-22 2007-11-20 Laboratoires Serono Sa Process of purification of hCG and recombinant hCG purified by that method
ATE448306T1 (de) 2000-09-01 2009-11-15 Blood Res Center Veränderte, in gewünschter konformation stabilisierte polypeptide und verfahren zu deren herstellung
AU2002246621A1 (en) * 2000-12-15 2002-08-12 The Johns Hopkins University The separation, identification and quantitation of protein mixtures
US20040067599A1 (en) * 2001-12-14 2004-04-08 Katz Joseph L. Separation identification and quantitation of protein mixtures
MXPA04006053A (es) * 2001-12-21 2005-03-31 Immunex Corp Metodos para purificacion de proteina.
US20050271639A1 (en) * 2002-08-22 2005-12-08 Penn Marc S Genetically engineered cells for therapeutic applications
CA2497209C (en) * 2002-09-06 2015-04-28 Genentech, Inc. Process for protein extraction
AU2004230670B2 (en) * 2003-01-09 2010-11-25 Genentech, Inc. Purification of polypeptides
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
CN100526453C (zh) * 2005-05-20 2009-08-12 麦克奥迪实业集团有限公司 激光显微切割后细胞收集方法
EP1926751A1 (de) * 2005-09-20 2008-06-04 Amgen Inc. Verfahren zur erzeugung von f(ab')2-antikörperfragmenten
AU2006329963B2 (en) * 2005-12-06 2011-06-09 Amgen Inc. Polishing steps used in multi-step protein purification processes
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
US8163886B2 (en) 2006-12-21 2012-04-24 Emd Millipore Corporation Purification of proteins
AU2008232739B2 (en) 2007-03-30 2014-03-27 The Cleveland Clinic Foundation Method of treating ischemic disorders
RU2009148891A (ru) 2007-06-01 2011-07-20 Ф.Хоффманн-Ля Рош Аг (Ch) Очистка иммуноглобулина
AU2008338525B2 (en) 2007-12-14 2015-04-02 Juventas Therapeutics, Inc. Compositions and methods of promoting wound healing
CN102257122B (zh) 2008-12-16 2015-07-29 Emd密理博公司 搅拌槽反应器及方法
JP2012513425A (ja) 2008-12-22 2012-06-14 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリンの精製
CN102740894B (zh) 2009-08-28 2015-07-15 克利夫兰临床医学基金会 用于治疗缺血组织的sdf-1递送
BR112012005485A2 (pt) * 2009-09-10 2016-04-19 Lonza Biologics Plc método e sistema para a purificação de polipeptídeo
DK2571903T3 (da) 2010-05-17 2019-11-04 Emd Millipore Corp Polymerer, der reagerer på stimuli, til oprensning af biomolekyler
AU2012340766B2 (en) 2011-11-23 2018-05-10 Medimmune, Llc Binding molecules specific for HER3 and uses thereof
US11305012B2 (en) 2013-09-24 2022-04-19 Medimmune, Llc Binding molecules specific for HER3 and uses thereof
US10745490B2 (en) 2014-04-11 2020-08-18 Celldex Therapeutics, Inc. Anti-ErbB antibodies and methods of use thereof

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CA1148872A (en) * 1979-04-06 1983-06-28 Eugene A. Ostreicher Filter with inorganic cationic colloidal silica
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WO1993008829A1 (en) * 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
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PT998486E (pt) * 1997-06-13 2007-08-21 Genentech Inc ''recuperação de proteínas por cromatografia seguida de filtração numa camada carregada''

Also Published As

Publication number Publication date
US20040138426A1 (en) 2004-07-15
DE69837760T3 (de) 2012-06-21
DE69837760T2 (de) 2008-02-28
US6322997B1 (en) 2001-11-27
JP2001510483A (ja) 2001-07-31
CA2289665C (en) 2005-08-09
EP0998486B1 (de) 2007-05-09
PT998486E (pt) 2007-08-21
US6716598B2 (en) 2004-04-06
AU7838898A (en) 1998-12-30
IL132838A (en) 2004-08-31
DE69837760D1 (de) 2007-06-21
IL132838A0 (en) 2001-03-19
WO1998056808A1 (en) 1998-12-17
EP0998486A1 (de) 2000-05-10
ES2287976T3 (es) 2007-12-16
CA2289665A1 (en) 1998-12-17
EP0998486B2 (de) 2012-02-01
US20020058324A1 (en) 2002-05-16
DK0998486T4 (da) 2012-05-14
US6121428A (en) 2000-09-19
AU735883C (en) 2002-02-07
AU735883B2 (en) 2001-07-19
DK0998486T3 (da) 2007-09-10

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