DK0947584T3 - Loxoprofen-indeholdende præparat til udvortes brug - Google Patents
Loxoprofen-indeholdende præparat til udvortes brugInfo
- Publication number
- DK0947584T3 DK0947584T3 DK97935867.8T DK97935867T DK0947584T3 DK 0947584 T3 DK0947584 T3 DK 0947584T3 DK 97935867 T DK97935867 T DK 97935867T DK 0947584 T3 DK0947584 T3 DK 0947584T3
- Authority
- DK
- Denmark
- Prior art keywords
- loxoprofen
- topical use
- containing preparation
- antiphlogistic
- acceptable salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/52—Propionic acid; Butyric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22352496 | 1996-08-26 | ||
PCT/JP1997/002936 WO1998008966A1 (fr) | 1996-08-26 | 1997-08-25 | Loxoprofen-containing preparation for external use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0947584T3 true DK0947584T3 (da) | 2011-07-18 |
Family
ID=16799501
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97935867.8T DK0947584T3 (da) | 1996-08-26 | 1997-08-25 | Loxoprofen-indeholdende præparat til udvortes brug |
Country Status (12)
Country | Link |
---|---|
US (1) | US6248350B1 (da) |
EP (1) | EP0947584B1 (da) |
JP (3) | JPH10120560A (da) |
KR (2) | KR100456668B1 (da) |
CN (2) | CN1231700A (da) |
AT (1) | ATE510531T1 (da) |
AU (1) | AU728797B2 (da) |
BR (1) | BR9711368A (da) |
CA (1) | CA2264960C (da) |
DK (1) | DK0947584T3 (da) |
ES (1) | ES2365203T3 (da) |
WO (1) | WO1998008966A1 (da) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8039026B1 (en) | 1997-07-28 | 2011-10-18 | Johnson & Johnson Consumer Companies, Inc | Methods for treating skin pigmentation |
US8093293B2 (en) | 1998-07-06 | 2012-01-10 | Johnson & Johnson Consumer Companies, Inc. | Methods for treating skin conditions |
US8106094B2 (en) | 1998-07-06 | 2012-01-31 | Johnson & Johnson Consumer Companies, Inc. | Compositions and methods for treating skin conditions |
US20080113025A1 (en) * | 1998-11-02 | 2008-05-15 | Elan Pharma International Limited | Compositions comprising nanoparticulate naproxen and controlled release hydrocodone |
US20090297602A1 (en) * | 1998-11-02 | 2009-12-03 | Devane John G | Modified Release Loxoprofen Compositions |
US7985404B1 (en) | 1999-07-27 | 2011-07-26 | Johnson & Johnson Consumer Companies, Inc. | Reducing hair growth, hair follicle and hair shaft size and hair pigmentation |
US7309688B2 (en) * | 2000-10-27 | 2007-12-18 | Johnson & Johnson Consumer Companies | Topical anti-cancer compositions and methods of use thereof |
US8431550B2 (en) | 2000-10-27 | 2013-04-30 | Johnson & Johnson Consumer Companies, Inc. | Topical anti-cancer compositions and methods of use thereof |
JP2002154989A (ja) * | 2000-11-14 | 2002-05-28 | Lion Corp | 眼科用組成物、及び生体粘膜への薬物の滞留性向上組成物 |
KR100405161B1 (ko) * | 2000-12-14 | 2003-11-12 | 신풍제약주식회사 | 록소프로펜 함유 근육주사제 조성물 |
US7192615B2 (en) | 2001-02-28 | 2007-03-20 | J&J Consumer Companies, Inc. | Compositions containing legume products |
KR20030000198A (ko) * | 2001-06-22 | 2003-01-06 | 해양전자장비 주식회사 | 어초 탐지 시스템 |
BR0314084A (pt) * | 2002-09-07 | 2005-07-05 | Johnson & Johnson Consumer Fr | Composições que compreendem produtos de soja e sais orgânicos de determinados metais |
EP1559426B1 (en) * | 2002-11-05 | 2011-02-09 | Lead Chemical Co. Ltd. | Percutaneous absorption preparations containing 3-methyl-1-phenyl-2-pyrazolin-5-one |
JP4468669B2 (ja) * | 2003-09-22 | 2010-05-26 | 久光製薬株式会社 | 低刺激性貼付剤 |
EP1685837A4 (en) * | 2003-11-12 | 2009-03-25 | Lead Chem Co Ltd | BRAIN PROTECTIVE AGENT OF THE TYPE ADMINISTERED BY PERCUTANEOUS ABSORPTION |
EP1815852B1 (en) * | 2004-11-05 | 2017-01-25 | Lead Chemical Co. Ltd. | Nonaqueous preparation for percutaneous absorption containing nonsteroidal antiflammatory analgesic |
US20060213815A1 (en) * | 2005-01-28 | 2006-09-28 | Wille John J | Hydrocarbon fume suppression by higher vapor pressure temperature oils |
CN101553213A (zh) * | 2006-12-06 | 2009-10-07 | 尼普洛外用药品株式会社 | 外用药物组合物及贴剂 |
EP2228063B1 (en) * | 2007-12-12 | 2012-02-01 | Teikoku Seiyaku Co., Ltd. | Loxoprofen-containing aqueous plaster |
JP2011037903A (ja) * | 2010-11-26 | 2011-02-24 | Daiichi Sankyo Co Ltd | 外用消炎鎮痛剤組成物 |
KR20140035879A (ko) * | 2011-01-24 | 2014-03-24 | 니프로 패치 가부시키가이샤 | 함수계 첩부제 |
JP5280472B2 (ja) * | 2011-03-02 | 2013-09-04 | 第一三共株式会社 | 外用消炎鎮痛剤組成物 |
JP6144944B2 (ja) * | 2012-03-29 | 2017-06-07 | 興和株式会社 | ロキソプロフェンを含有する医薬組成物 |
KR20140100422A (ko) * | 2013-02-05 | 2014-08-14 | 닛토덴코 가부시키가이샤 | 백신 조성물 |
JP6060742B2 (ja) * | 2013-03-08 | 2017-01-18 | ライオン株式会社 | 外用液体組成物 |
EP2982369A4 (en) * | 2013-04-01 | 2016-11-02 | Daiichi Sankyo Co Ltd | PREPARATION FOR TREATMENT OF INFLICTION IN HORSES |
JP6189668B2 (ja) * | 2013-07-31 | 2017-08-30 | 興和株式会社 | ロキソプロフェン含有外用塗布剤 |
JP2015083563A (ja) * | 2013-09-18 | 2015-04-30 | 第一三共ヘルスケア株式会社 | ロキソプロフェン配合皮膚外用液剤 |
EP2926810A1 (en) | 2014-03-31 | 2015-10-07 | Sanovel Ilac Sanayi ve Ticaret A.S. | Oral liquid pharmaceutical formulations of loxoprofen |
EP2926832A1 (en) * | 2014-03-31 | 2015-10-07 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical formulations of loxoprofen for topical use |
EP2939666A1 (en) | 2014-04-29 | 2015-11-04 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical formulations of loxoprofen |
EA201692424A1 (ru) | 2014-06-30 | 2017-04-28 | Сановель Илач Санайи Ве Тиджарет А.Ш. | Комбинации локсопрофена и агониста рецепторов гамма-аминомасляной кислоты |
WO2016046189A1 (en) | 2014-09-24 | 2016-03-31 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Loxoprofen and antispastic drug combinations |
WO2017111167A1 (ja) | 2015-12-25 | 2017-06-29 | 興和株式会社 | ロキソプロフェンを含有する医薬製剤 |
CN108210929A (zh) * | 2016-12-21 | 2018-06-29 | 北京泰德制药股份有限公司 | 一种含有依托考昔的药物组合物及其制备方法 |
CN107951866A (zh) * | 2017-12-06 | 2018-04-24 | 北京茗泽中和药物研究有限公司 | 洛索洛芬钠贴剂 |
CN109776300B (zh) * | 2019-02-28 | 2020-08-07 | 浙江大学 | 洛索洛芬钠的合成方法 |
CN111635309B (zh) * | 2019-03-01 | 2024-03-12 | 华创合成制药股份有限公司 | 一种新型解热镇痛药物及其制备方法和用途 |
CN111635315B (zh) * | 2019-03-01 | 2024-03-12 | 华创合成制药股份有限公司 | 一种解热镇痛药物及其制备方法和用途 |
CN110746290A (zh) * | 2019-11-11 | 2020-02-04 | 威海厚普生物科技有限公司 | 一种高纯度洛索洛芬钠的新成盐方法 |
CN113121331B (zh) * | 2019-12-31 | 2024-01-05 | 华创合成制药股份有限公司 | 具有环丙基的苯氧芳酸类化合物及其药学上可接受的盐,以及它们的制备方法和应用 |
JP2022096991A (ja) * | 2020-12-18 | 2022-06-30 | 小林製薬株式会社 | 外用医薬組成物 |
CN113069437A (zh) * | 2020-12-29 | 2021-07-06 | 北京湃驰泰克医药科技有限公司 | 一种含有洛索洛芬及其药用盐的外用凝胶贴膏剂及其制备方法 |
CN115444837B (zh) * | 2022-10-13 | 2023-08-22 | 湖南九典制药股份有限公司 | 一种洛索洛芬经皮给药系统及其制备方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS574919A (en) | 1980-06-09 | 1982-01-11 | Sankyo Co Ltd | Anti-inflammatory for external use |
JPH0747535B2 (ja) * | 1985-11-26 | 1995-05-24 | 日東電工株式会社 | 消炎鎮痛用貼付剤 |
JPS62181226A (ja) * | 1986-02-05 | 1987-08-08 | Ikeda Mohandou:Kk | 消炎鎮痛外用剤 |
JPH0794394B2 (ja) * | 1986-12-24 | 1995-10-11 | 前田薬品工業株式会社 | 消炎鎮痛外用貼付剤 |
US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
JPH07112984B2 (ja) * | 1989-04-28 | 1995-12-06 | 久光製薬株式会社 | 泡状エアゾール製剤 |
CA2042583C (en) * | 1989-07-28 | 1995-06-20 | Akira Nakagawa | Foamable aerosol preparation |
WO1991001716A1 (en) * | 1989-08-03 | 1991-02-21 | Hisamitsu Pharmaceutical Co., Inc. | Skin cream preparation for external use |
JP2839164B2 (ja) * | 1989-12-25 | 1998-12-16 | 帝國製薬株式会社 | 消炎鎮痛貼付剤 |
JP3243564B2 (ja) | 1990-08-20 | 2002-01-07 | リードケミカル株式会社 | 外用貼付剤 |
JP3207212B2 (ja) | 1991-03-01 | 2001-09-10 | 久光製薬株式会社 | 吸収促進剤およびこれを含有する外用剤 |
JP3541849B2 (ja) * | 1991-04-19 | 2004-07-14 | 久光製薬株式会社 | 消炎鎮痛貼付剤 |
EP0607434B1 (en) * | 1991-08-30 | 1999-01-27 | Hisamitsu Pharmaceutical Co., Inc. | Anti-inflammatory analgesic plaster |
JP2887549B2 (ja) * | 1992-11-06 | 1999-04-26 | 前田薬品工業株式会社 | 使用性の改善された消炎鎮痛用皮膚外用貼付剤 |
JPH06199701A (ja) * | 1992-12-29 | 1994-07-19 | Lion Corp | 外用消炎鎮痛剤 |
JP3466305B2 (ja) | 1994-12-12 | 2003-11-10 | 久光製薬株式会社 | 溶解剤および該溶解剤を含有する外用製剤 |
JPH08295624A (ja) * | 1995-04-26 | 1996-11-12 | Read Chem Kk | プラスター基剤、その製造方法、該基剤を使用した外用貼 付剤 |
-
1997
- 1997-08-22 JP JP9226020A patent/JPH10120560A/ja active Pending
- 1997-08-25 KR KR10-1999-7001529A patent/KR100456668B1/ko not_active IP Right Cessation
- 1997-08-25 BR BR9711368A patent/BR9711368A/pt not_active Application Discontinuation
- 1997-08-25 WO PCT/JP1997/002936 patent/WO1998008966A1/ja active IP Right Grant
- 1997-08-25 EP EP97935867A patent/EP0947584B1/en not_active Expired - Lifetime
- 1997-08-25 ES ES97935867T patent/ES2365203T3/es not_active Expired - Lifetime
- 1997-08-25 CN CN97198272A patent/CN1231700A/zh active Pending
- 1997-08-25 US US09/242,555 patent/US6248350B1/en not_active Expired - Lifetime
- 1997-08-25 DK DK97935867.8T patent/DK0947584T3/da active
- 1997-08-25 CN CN200910009743A patent/CN101658486A/zh active Pending
- 1997-08-25 AT AT97935867T patent/ATE510531T1/de active
- 1997-08-25 KR KR10-2003-7008523A patent/KR100403486B1/ko not_active IP Right Cessation
- 1997-08-25 AU AU38686/97A patent/AU728797B2/en not_active Expired
- 1997-08-25 CA CA002264960A patent/CA2264960C/en not_active Expired - Lifetime
-
2007
- 2007-05-29 JP JP2007141490A patent/JP2007291118A/ja active Pending
- 2007-12-11 JP JP2007320033A patent/JP5137548B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP5137548B2 (ja) | 2013-02-06 |
KR100403486B1 (ko) | 2003-11-01 |
ATE510531T1 (de) | 2011-06-15 |
CN101658486A (zh) | 2010-03-03 |
EP0947584B1 (en) | 2011-05-25 |
JP2007291118A (ja) | 2007-11-08 |
WO1998008966A1 (fr) | 1998-03-05 |
AU728797B2 (en) | 2001-01-18 |
US6248350B1 (en) | 2001-06-19 |
KR100456668B1 (ko) | 2004-11-10 |
EP0947584A1 (en) | 1999-10-06 |
CN1231700A (zh) | 1999-10-13 |
WO1998008966A8 (fr) | 1999-08-19 |
BR9711368A (pt) | 1999-08-17 |
CA2264960A1 (en) | 1998-03-05 |
EP0947584A4 (en) | 2002-10-23 |
CA2264960C (en) | 2003-04-22 |
JP2008074873A (ja) | 2008-04-03 |
KR20000030025A (ko) | 2000-05-25 |
JPH10120560A (ja) | 1998-05-12 |
AU3868697A (en) | 1998-03-19 |
ES2365203T3 (es) | 2011-09-26 |
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