ATE510531T1 - Loxoprofen-enthaltendes präparat zur äusserlichen anwendung - Google Patents

Loxoprofen-enthaltendes präparat zur äusserlichen anwendung

Info

Publication number
ATE510531T1
ATE510531T1 AT97935867T AT97935867T ATE510531T1 AT E510531 T1 ATE510531 T1 AT E510531T1 AT 97935867 T AT97935867 T AT 97935867T AT 97935867 T AT97935867 T AT 97935867T AT E510531 T1 ATE510531 T1 AT E510531T1
Authority
AT
Austria
Prior art keywords
external use
containing loxoprofen
preparation containing
loxoprofen
antiphlogistic
Prior art date
Application number
AT97935867T
Other languages
English (en)
Inventor
Masao Mori
Hidetsune Tamaoki
Tamaki Horiuchi
Original Assignee
Lead Chem Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lead Chem Co Ltd filed Critical Lead Chem Co Ltd
Application granted granted Critical
Publication of ATE510531T1 publication Critical patent/ATE510531T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/52—Propionic acid; Butyric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97935867T 1996-08-26 1997-08-25 Loxoprofen-enthaltendes präparat zur äusserlichen anwendung ATE510531T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22352496 1996-08-26
PCT/JP1997/002936 WO1998008966A1 (fr) 1996-08-26 1997-08-25 Loxoprofen-containing preparation for external use

Publications (1)

Publication Number Publication Date
ATE510531T1 true ATE510531T1 (de) 2011-06-15

Family

ID=16799501

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97935867T ATE510531T1 (de) 1996-08-26 1997-08-25 Loxoprofen-enthaltendes präparat zur äusserlichen anwendung

Country Status (12)

Country Link
US (1) US6248350B1 (de)
EP (1) EP0947584B1 (de)
JP (3) JPH10120560A (de)
KR (2) KR100456668B1 (de)
CN (2) CN101658486A (de)
AT (1) ATE510531T1 (de)
AU (1) AU728797B2 (de)
BR (1) BR9711368A (de)
CA (1) CA2264960C (de)
DK (1) DK0947584T3 (de)
ES (1) ES2365203T3 (de)
WO (1) WO1998008966A1 (de)

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JP6144944B2 (ja) * 2012-03-29 2017-06-07 興和株式会社 ロキソプロフェンを含有する医薬組成物
RU2014102945A (ru) * 2013-02-05 2015-08-10 Нитто Денко Корпорейшн Вакцинная композиция
JP6060742B2 (ja) * 2013-03-08 2017-01-18 ライオン株式会社 外用液体組成物
EP2982369A4 (de) * 2013-04-01 2016-11-02 Daiichi Sankyo Co Ltd Präparat zur behandlung von entzündungen bei pferden
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JP2015083563A (ja) * 2013-09-18 2015-04-30 第一三共ヘルスケア株式会社 ロキソプロフェン配合皮膚外用液剤
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JPWO2017111167A1 (ja) 2015-12-25 2018-11-29 興和株式会社 ロキソプロフェンを含有する医薬製剤
CN108210929A (zh) * 2016-12-21 2018-06-29 北京泰德制药股份有限公司 一种含有依托考昔的药物组合物及其制备方法
CN107951866A (zh) * 2017-12-06 2018-04-24 北京茗泽中和药物研究有限公司 洛索洛芬钠贴剂
CN109776300B (zh) * 2019-02-28 2020-08-07 浙江大学 洛索洛芬钠的合成方法
CN111635309B (zh) * 2019-03-01 2024-03-12 华创合成制药股份有限公司 一种新型解热镇痛药物及其制备方法和用途
CN111635315B (zh) * 2019-03-01 2024-03-12 华创合成制药股份有限公司 一种解热镇痛药物及其制备方法和用途
CN110746290A (zh) * 2019-11-11 2020-02-04 威海厚普生物科技有限公司 一种高纯度洛索洛芬钠的新成盐方法
CN113121331B (zh) * 2019-12-31 2024-01-05 华创合成制药股份有限公司 具有环丙基的苯氧芳酸类化合物及其药学上可接受的盐，以及它们的制备方法和应用
JP2022096991A (ja) * 2020-12-18 2022-06-30 小林製薬株式会社 外用医薬組成物
CN113069437A (zh) * 2020-12-29 2021-07-06 北京湃驰泰克医药科技有限公司 一种含有洛索洛芬及其药用盐的外用凝胶贴膏剂及其制备方法
CN115444837B (zh) * 2022-10-13 2023-08-22 湖南九典制药股份有限公司 一种洛索洛芬经皮给药系统及其制备方法

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Also Published As

Publication number Publication date
US6248350B1 (en) 2001-06-19
ES2365203T3 (es) 2011-09-26
JP2008074873A (ja) 2008-04-03
EP0947584A4 (de) 2002-10-23
CA2264960A1 (en) 1998-03-05
CA2264960C (en) 2003-04-22
WO1998008966A1 (fr) 1998-03-05
AU728797B2 (en) 2001-01-18
AU3868697A (en) 1998-03-19
JP5137548B2 (ja) 2013-02-06
EP0947584B1 (de) 2011-05-25
DK0947584T3 (da) 2011-07-18
EP0947584A1 (de) 1999-10-06
JP2007291118A (ja) 2007-11-08
JPH10120560A (ja) 1998-05-12
KR100456668B1 (ko) 2004-11-10
CN1231700A (zh) 1999-10-13
KR20000030025A (ko) 2000-05-25
BR9711368A (pt) 1999-08-17
WO1998008966A8 (fr) 1999-08-19
KR100403486B1 (ko) 2003-11-01
CN101658486A (zh) 2010-03-03

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