DK0943326T3 - Pulveragtigt præparat til nasal administration - Google Patents

Pulveragtigt præparat til nasal administration

Info

Publication number
DK0943326T3
DK0943326T3 DK97905398T DK97905398T DK0943326T3 DK 0943326 T3 DK0943326 T3 DK 0943326T3 DK 97905398 T DK97905398 T DK 97905398T DK 97905398 T DK97905398 T DK 97905398T DK 0943326 T3 DK0943326 T3 DK 0943326T3
Authority
DK
Denmark
Prior art keywords
water
absorbing
base material
drug
gel
Prior art date
Application number
DK97905398T
Other languages
English (en)
Other versions
DK0943326T4 (da
Inventor
Masahiko Dohi
Yoshihisa Nishibe
Yuji Makino
Takao Fujii
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26378964&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0943326(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of DK0943326T3 publication Critical patent/DK0943326T3/da
Application granted granted Critical
Publication of DK0943326T4 publication Critical patent/DK0943326T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK97905398T 1996-02-27 1997-02-26 Pulveragtigt præparat til nasal administration DK0943326T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3955396 1996-02-27
JP4107996 1996-02-28
PCT/JP1997/000541 WO1997031626A1 (fr) 1996-02-27 1997-02-26 Composition pulverulente destinee a une adminstration nasale

Publications (2)

Publication Number Publication Date
DK0943326T3 true DK0943326T3 (da) 2003-12-08
DK0943326T4 DK0943326T4 (da) 2007-01-22

Family

ID=26378964

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97905398T DK0943326T4 (da) 1996-02-27 1997-02-26 Pulveragtigt præparat til nasal administration

Country Status (13)

Country Link
US (3) US6881423B2 (da)
EP (1) EP0943326B2 (da)
JP (1) JP3634380B2 (da)
KR (1) KR100568436B1 (da)
CN (1) CN1155368C (da)
AT (1) ATE247456T1 (da)
AU (1) AU722319B2 (da)
CA (1) CA2247191C (da)
DE (1) DE69724272T3 (da)
DK (1) DK0943326T4 (da)
ES (1) ES2205177T5 (da)
PT (1) PT943326E (da)
WO (1) WO1997031626A1 (da)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3634380B2 (ja) * 1996-02-27 2005-03-30 帝人株式会社 粉末状経鼻投与組成物
TWI243687B (en) 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
DE69932144T8 (de) 1998-08-26 2007-10-04 Teijin Ltd. Pulverförmige pernasale mittel
JP2002531489A (ja) * 1998-12-09 2002-09-24 カイロン コーポレイション 中枢神経系への神経栄養剤の投与
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AR026073A1 (es) 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
KR100587237B1 (ko) * 2000-11-29 2006-06-07 이토햄 가부시키가이샤 분말제제 및 그의 제조방법
GB2378383A (en) * 2001-06-06 2003-02-12 Gursharan Moonga Nasal delivery of pharmaceutical compositions in powder form
CN100341567C (zh) * 2001-07-05 2007-10-10 产业化研究株式会社 胰岛素的经鼻给药用组合物
KR20040058324A (ko) * 2001-11-26 2004-07-03 다이이찌 산토리 파마 가부시키가이샤 경비흡수용 의약 조성물
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US20080260838A1 (en) * 2003-08-01 2008-10-23 Mannkind Corporation Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
WO2004024187A2 (en) * 2002-09-13 2004-03-25 Zicam, Llc. Compositions to reduce congestion and methods for application thereof to the nasal membrane
US7638138B2 (en) 2003-02-21 2009-12-29 Translational Research, Ltd. Compositions for nasal administration of pharmaceuticals
WO2004084859A2 (en) * 2003-03-21 2004-10-07 Nastech Pharmaceutical Company Inc. Nasal calcitonin formulations containing chlorobutanol
AU2003220808B2 (en) 2003-03-27 2008-08-21 Bioactis Limited Powder medicine applicator for nasal cavity
GB0315632D0 (en) 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations
JP4922762B2 (ja) * 2004-08-10 2012-04-25 株式会社新日本科学 速効性でかつ高い吸収性を可能とする経鼻投与用組成物
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
US7115561B2 (en) * 2004-09-22 2006-10-03 Patterson James A Medicament composition and method of administration
ES2399053T3 (es) 2004-10-11 2013-03-25 Nasaleze Patents Limited Composiciones para administración intranasal
GB2420707A (en) * 2004-10-11 2006-06-07 Nasaleze Patents Ltd Compositions for intranasal administration
WO2006040596A2 (en) * 2004-10-11 2006-04-20 Nasaleze Ppm Limited Compositions for intranasal administration
JP2009504767A (ja) * 2005-08-17 2009-02-05 フレミング・アンド・カンパニー・ファーマシューティカルズ ビタミンｂ１２鼻用スプレーおよび使用方法
US20090317377A1 (en) 2005-08-26 2009-12-24 Yeomans David C Therapy procedure for drug delivery for trigeminal pain
DK1937219T3 (da) 2005-09-14 2016-02-15 Mannkind Corp Fremgangsmåde til lægemiddelformulering baseret på at øge affiniteten af krystallinske mikropartikeloverflader til aktive stoffer
IN2015DN00888A (da) 2006-02-22 2015-07-10 Mannkind Corp
CN101668544B (zh) 2006-12-26 2013-04-24 株式会社新日本科学 经鼻投用制剂
EP2954893A1 (en) * 2007-10-24 2015-12-16 MannKind Corporation An inhalable dry powder formulation comprising glp-1 for use in the treatment of hyperglycemia and diabetes
KR101933816B1 (ko) 2008-06-13 2019-03-29 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
EP2429495A4 (en) * 2009-05-15 2014-01-22 Shin Nippon Biomedical Lab Ltd INTRANASAL PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PHARMACOKINETICS
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011013003A2 (en) * 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
PT2474559E (pt) 2009-09-02 2015-04-13 Nippon Soda Co Partículas de hidroxipropilcelulose
EP2298286B8 (en) * 2009-09-18 2017-08-09 SiTec PharmaBio SL Process for dewatering of product powders
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
CN102905717B (zh) 2010-03-19 2016-09-07 第一三共株式会社 经鼻投与用组合物及其制造方法
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
SE536091C2 (sv) 2011-04-14 2013-04-30 Pep Tonic Medical Ab Farmaceutisk komposition innehållande oxytocin eller fragment eller varianter därav och åtminstone en icke-jonisk cellulosaeter
US9757388B2 (en) 2011-05-13 2017-09-12 Acerus Pharmaceuticals Srl Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels
US20130045958A1 (en) 2011-05-13 2013-02-21 Trimel Pharmaceuticals Corporation Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
AR086400A1 (es) 2011-05-13 2013-12-11 Trimel Pharmaceuticals Corp Formulaciones en gel intranasal de testosterona en dosis de menor potencia y uso de las mismas para el tratamiento de la anorgasmia o el trastorno de deseo sexual hipoactivo
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
JP5717658B2 (ja) * 2012-01-13 2015-05-13 シスメックス株式会社 副腎皮質刺激ホルモンの検出方法および吸着剤
US9789071B2 (en) 2012-06-27 2017-10-17 G2B Pharma, Inc. Intranasal formulation of epinephrine for the treatment of anaphylaxis
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
ES2804702T3 (es) * 2013-03-04 2021-02-09 Besins Healthcare Lu Sarl Composiciones farmacéuticas secas que comprenden nanopartículas de agente activo unidas a partículas de portador
US11744838B2 (en) 2013-03-15 2023-09-05 Acerus Biopharma Inc. Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US20160220489A1 (en) * 2013-09-03 2016-08-04 G2B Pharma Inc. Intranasal Formulation for the Treatment of Cardiopulmonary Resuscitation (CPR), Cardiac Life Support (CLS), Anaphylaxis and/or Anaphylactoid Reactions
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP4331670A3 (en) 2015-01-07 2024-05-29 Tonix Pharma Limited Magnesium-containing oxytocin formulations and methods of use
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
JP7321096B2 (ja) * 2017-11-27 2023-08-04 あすか製薬株式会社 粉末経鼻投与製剤
CN108158978A (zh) * 2018-03-26 2018-06-15 厦门传福堂药业有限公司 一种高分子水性凝胶及其制备方法和用途
CA3138846A1 (en) * 2019-05-16 2020-11-19 Shin Nippon Biomedical Laboratories, Ltd. Powder formulation for intranasal administration, and manufacturing method thereof
WO2022132018A1 (en) * 2020-12-16 2022-06-23 Liw Innovation Ab A new powder composition

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6034925B2 (ja) * 1979-07-31 1985-08-12 帝人株式会社 持続性鼻腔用製剤およびその製造法
JPS607965B2 (ja) * 1980-08-07 1985-02-28 帝人株式会社 鼻腔粘膜投与用粉剤の製造法
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
EP0187433B1 (en) 1983-08-01 1990-12-27 Teijin Limited Powdery pharmaceutical composition suitable for application to mucosa of oral or nasal cavity
JPS6032714A (ja) * 1983-08-01 1985-02-19 Teijin Ltd 鼻腔粘膜に適用するための安定化された粉末状薬学的組成物
JPS6034925A (ja) 1983-08-04 1985-02-22 Mitsubishi Chem Ind Ltd ２−ヒドロキシイソフタルアルデヒド類の製造法
JPS60224616A (ja) * 1984-04-24 1985-11-09 Teijin Ltd 経鼻投与用組成物
JPS6242888A (ja) 1985-08-21 1987-02-24 カシオ計算機株式会社 太陽電池を備えたｉｃカ−ド
GB2193891B (en) 1986-08-18 1990-07-25 Sandoz Ltd Nasal pharmaceutical composition containing a somatostatin anologue.
JP3068924B2 (ja) 1990-11-29 2000-07-24 旭硝子株式会社 熱線遮断膜
DE69222295T2 (de) 1992-05-26 1998-04-09 The Procter & Gamble Co., Cincinnati, Ohio Pulverförmige pharmazeutische Zusammensetzung
AU660824B2 (en) * 1992-06-12 1995-07-06 Teijin Limited Pharmaceutical preparation for intra-airway administration
DE69430295T2 (de) * 1993-07-30 2002-10-31 Teijin Ltd., Osaka Pulver zur nasalen Verabreichung peptidischer oder proteinischer Arzneistoffe
JPH07242550A (ja) 1994-03-02 1995-09-19 Teijin Ltd 二次性副甲状腺機能亢進症治療剤
JP3634380B2 (ja) * 1996-02-27 2005-03-30 帝人株式会社 粉末状経鼻投与組成物

Also Published As

Publication number Publication date
DE69724272T3 (de) 2007-05-10
ES2205177T3 (es) 2004-05-01
JP3634380B2 (ja) 2005-03-30
US6881423B2 (en) 2005-04-19
US20020012688A1 (en) 2002-01-31
EP0943326A4 (en) 2000-12-20
KR100568436B1 (ko) 2007-04-25
PT943326E (pt) 2003-12-31
DE69724272D1 (de) 2003-09-25
WO1997031626A1 (fr) 1997-09-04
CN1216464A (zh) 1999-05-12
CN1155368C (zh) 2004-06-30
EP0943326B2 (en) 2006-12-20
EP0943326B1 (en) 2003-08-20
US8206748B2 (en) 2012-06-26
US7731990B2 (en) 2010-06-08
AU722319B2 (en) 2000-07-27
DE69724272T2 (de) 2004-06-09
ATE247456T1 (de) 2003-09-15
CA2247191C (en) 2005-01-04
DK0943326T4 (da) 2007-01-22
EP0943326A1 (en) 1999-09-22
KR19990087261A (ko) 1999-12-15
CA2247191A1 (en) 1997-09-04
ES2205177T5 (es) 2007-08-01
US20040219108A1 (en) 2004-11-04
US20100047206A1 (en) 2010-02-25
AU2230297A (en) 1997-09-16

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