DK0928294T3 - Fremgangsmåde og apparat til fremstilling af en acellulær rød blodlegeme-erstatning - Google Patents

Fremgangsmåde og apparat til fremstilling af en acellulær rød blodlegeme-erstatning

Info

Publication number
DK0928294T3
DK0928294T3 DK97919943T DK97919943T DK0928294T3 DK 0928294 T3 DK0928294 T3 DK 0928294T3 DK 97919943 T DK97919943 T DK 97919943T DK 97919943 T DK97919943 T DK 97919943T DK 0928294 T3 DK0928294 T3 DK 0928294T3
Authority
DK
Denmark
Prior art keywords
producing
red blood
blood cell
cell replacement
acellular red
Prior art date
Application number
DK97919943T
Other languages
Danish (da)
English (en)
Inventor
Richard E Dewoskin
Marc D Doubleday
Original Assignee
Northfield Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northfield Lab filed Critical Northfield Lab
Application granted granted Critical
Publication of DK0928294T3 publication Critical patent/DK0928294T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08HDERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00Macromolecular products derived from proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/829Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97919943T 1996-03-28 1997-03-27 Fremgangsmåde og apparat til fremstilling af en acellulær rød blodlegeme-erstatning DK0928294T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1438996P 1996-03-28 1996-03-28
PCT/US1997/005088 WO1997035883A1 (en) 1996-03-28 1997-03-27 Method and apparatus for preparing an acellular red blood cell substitute

Publications (1)

Publication Number Publication Date
DK0928294T3 true DK0928294T3 (da) 2003-09-22

Family

ID=21765191

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97919943T DK0928294T3 (da) 1996-03-28 1997-03-27 Fremgangsmåde og apparat til fremstilling af en acellulær rød blodlegeme-erstatning

Country Status (26)

Country Link
US (5) US6498141B2 (bg)
EP (1) EP0928294B1 (bg)
JP (1) JP2000507947A (bg)
CN (1) CN1129608C (bg)
AP (1) AP1028A (bg)
AT (1) ATE241646T1 (bg)
AU (1) AU740210B2 (bg)
BG (1) BG63919B1 (bg)
BR (1) BR9708388A (bg)
CA (1) CA2250274C (bg)
CZ (1) CZ299357B6 (bg)
DE (1) DE69722422T2 (bg)
DK (1) DK0928294T3 (bg)
ES (1) ES2200177T3 (bg)
IL (1) IL126376A (bg)
IS (1) IS4854A (bg)
NO (1) NO324121B1 (bg)
NZ (2) NZ332067A (bg)
OA (1) OA10884A (bg)
PL (1) PL187923B1 (bg)
PT (1) PT928294E (bg)
RO (1) RO121089B1 (bg)
RU (1) RU2203087C2 (bg)
SK (1) SK134398A3 (bg)
UA (1) UA64710C2 (bg)
WO (1) WO1997035883A1 (bg)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2200177T3 (es) * 1996-03-28 2004-03-01 Northfield Laboratories, Inc. Procedimiento y aparato para preparar un sustituto acecular de globlulo rojo.
JP2004538264A (ja) 2001-04-18 2004-12-24 ノースフィールド ラボラトリーズ 安定化ヘモグロビン溶液の保管のための可撓性容器システム
DE10220992A1 (de) * 2002-05-11 2003-12-04 Sanguibiotech Ag Verwendung eines oder mehrerer Sauerstoffträger, ausgewählt aus Hämoglobin, Myoglobin und Derivaten hiervon zur Behandlung einer Organfunktionsstörung infolge eines akuten Versorgungsmangels und zur Behandlung/Vermeidung einer Gewebeschädigung infolge einer solchen Störung
EP1553968A4 (en) * 2002-10-03 2009-06-24 Northfield Lab METHOD FOR TREATING PATIENTS WITH MASSIVE BLOOD LOSS
US7135553B2 (en) * 2003-01-29 2006-11-14 Northfield Laboratories, Inc. Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing
SE528214C2 (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
WO2007087570A2 (en) * 2006-01-24 2007-08-02 Northfield Laboratories, Inc. Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
RU2340354C1 (ru) * 2007-06-05 2008-12-10 Общество с ограниченной ответственностью "Геленпол" Кровезаменитель с функцией переноса кислорода
RU2361608C1 (ru) * 2008-03-18 2009-07-20 Общество С Ограниченной Ответственностью "Научно-Производственная Компания "Медбиофарм" Кровезаменитель с функцией переноса кислорода, фармацевтическая композиция (варианты)
JP7387597B2 (ja) 2017-07-18 2023-11-28 ヴァーテック・バイオ・インコーポレイテッド ヘモグロビンを含む代用血液及び作製方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194590A (en) * 1986-06-20 1993-03-16 Northfield Laboratories, Inc. Acellular red blood cell substitute
US4826811A (en) * 1986-06-20 1989-05-02 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5464814A (en) * 1986-06-20 1995-11-07 Northfield Laboratories, Inc. Acellular red blood cell substitute
IL87708A (en) * 1988-09-08 1994-04-12 Technion Inst For Research And Hemoglobin-based blood substitute possessing a colloid oncotic pressure substantially similar to human blood and method for the preparation thereof
SE9001378D0 (sv) * 1990-04-18 1990-04-18 Kabivitrum Ab A method for the preparation of pyridoxylated hemoglobin
TW381022B (en) * 1993-08-16 2000-02-01 Hsia Jen Chang Compositions and methods utilizing nitroxides to avoid oxygen toxicity, particularly in stabilized, polymerized, conjugated, or encapsulated hemoglobin used as a red cell substitute
ES2200177T3 (es) * 1996-03-28 2004-03-01 Northfield Laboratories, Inc. Procedimiento y aparato para preparar un sustituto acecular de globlulo rojo.
US5998361A (en) * 1996-10-18 1999-12-07 University Of Maryland At Baltimore Polymerized hemoglobin

Also Published As

Publication number Publication date
EP0928294A1 (en) 1999-07-14
US20020025343A1 (en) 2002-02-28
IS4854A (is) 1998-09-28
NO324121B1 (no) 2007-08-27
CN1219939A (zh) 1999-06-16
NZ538045A (en) 2006-11-30
CA2250274A1 (en) 1997-10-02
BG102810A (bg) 1999-09-30
DE69722422D1 (de) 2003-07-03
OA10884A (en) 2001-10-11
EP0928294B1 (en) 2003-05-28
ES2200177T3 (es) 2004-03-01
US20030191050A1 (en) 2003-10-09
AU740210B2 (en) 2001-11-01
US20100197566A1 (en) 2010-08-05
CN1129608C (zh) 2003-12-03
JP2000507947A (ja) 2000-06-27
BR9708388A (pt) 2000-01-04
WO1997035883A1 (en) 1997-10-02
IL126376A0 (en) 1999-05-09
AU2425397A (en) 1997-10-17
UA64710C2 (en) 2004-03-15
CZ310098A3 (cs) 1999-09-15
CZ299357B6 (cs) 2008-07-02
NO984473D0 (no) 1998-09-25
CA2250274C (en) 2003-09-16
AP1028A (en) 2001-11-30
IL126376A (en) 2009-09-22
NO984473L (no) 1998-11-25
PT928294E (pt) 2003-10-31
RU2203087C2 (ru) 2003-04-27
AP9801353A0 (en) 1998-09-30
ATE241646T1 (de) 2003-06-15
PL187923B1 (pl) 2004-11-30
BG63919B1 (bg) 2003-06-30
PL329108A1 (en) 1999-03-15
US6498141B2 (en) 2002-12-24
US7521417B2 (en) 2009-04-21
DE69722422T2 (de) 2004-05-06
US20050065067A1 (en) 2005-03-24
US20080108555A1 (en) 2008-05-08
RO121089B1 (ro) 2006-12-29
NZ332067A (en) 2001-03-30
SK134398A3 (en) 2001-01-18

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