DK0927024T3 - Indretning og fremgangsmåde til behandling af öjensygdomme - Google Patents

Indretning og fremgangsmåde til behandling af öjensygdomme

Info

Publication number
DK0927024T3
DK0927024T3 DK97916936T DK97916936T DK0927024T3 DK 0927024 T3 DK0927024 T3 DK 0927024T3 DK 97916936 T DK97916936 T DK 97916936T DK 97916936 T DK97916936 T DK 97916936T DK 0927024 T3 DK0927024 T3 DK 0927024T3
Authority
DK
Denmark
Prior art keywords
treatment
eye diseases
image
eye
periocularly
Prior art date
Application number
DK97916936T
Other languages
Danish (da)
English (en)
Inventor
Joseph P Hammang
Peter D Spear
E Edward Baetge
William G Tsiaras
Original Assignee
Neurotech Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurotech Sa filed Critical Neurotech Sa
Application granted granted Critical
Publication of DK0927024T3 publication Critical patent/DK0927024T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • A61K2035/128—Immunoprotecting barriers, e.g. jackets, diffusion chambers capsules, e.g. microcapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK97916936T 1996-03-22 1997-03-24 Indretning og fremgangsmåde til behandling af öjensygdomme DK0927024T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/620,982 US5904144A (en) 1996-03-22 1996-03-22 Method for treating ophthalmic diseases
PCT/US1997/004701 WO1997034586A2 (en) 1996-03-22 1997-03-24 Device and method for treating ophthalmic diseases

Publications (1)

Publication Number Publication Date
DK0927024T3 true DK0927024T3 (da) 2005-08-29

Family

ID=24488233

Family Applications (2)

Application Number Title Priority Date Filing Date
DK97916936T DK0927024T3 (da) 1996-03-22 1997-03-24 Indretning og fremgangsmåde til behandling af öjensygdomme
DK05010733.3T DK1574209T3 (da) 1996-03-22 1997-03-24 Fremgangsmåde til behandling af ophthalmiske sygdomme

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK05010733.3T DK1574209T3 (da) 1996-03-22 1997-03-24 Fremgangsmåde til behandling af ophthalmiske sygdomme

Country Status (10)

Country Link
US (1) US5904144A (enExample)
EP (2) EP1574209B1 (enExample)
JP (3) JP2000507854A (enExample)
AT (2) ATE459335T1 (enExample)
AU (1) AU716400B2 (enExample)
CA (1) CA2264895C (enExample)
DE (2) DE69733357T2 (enExample)
DK (2) DK0927024T3 (enExample)
ES (2) ES2242223T3 (enExample)
WO (1) WO1997034586A2 (enExample)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299895B1 (en) * 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
IL128941A (en) * 1996-09-13 2007-05-15 Advanced Medicine Res Inst An eye preparation that contains a neurotrophic factor for the treatment of a functional disease of the optic nerve
DE19718826A1 (de) * 1997-05-05 1998-11-12 Marion S Dr Eckmiller Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung
AU9198898A (en) * 1997-09-17 1999-04-05 Alcon Laboratories, Inc. Methods for treating ocular diseases
US7282482B2 (en) * 1998-04-08 2007-10-16 The Regents Of The University Of California NGF for the prevention of demyelination in the nervous system
WO2000040089A1 (en) * 1999-01-05 2000-07-13 Massachusetts Eye And Ear Infirmary Targeted transscleral controlled release drug delivery to the retina and choroid
US6361771B1 (en) * 1999-04-06 2002-03-26 Neurotech S.A. ARPE-19 as a platform cell line for encapsulated cell-based delivery
US20070071734A1 (en) * 1999-04-06 2007-03-29 Weng Tao ARPE-19 as platform cell line for encapsulated cell-based delivery
CA2372699A1 (en) * 1999-05-07 2000-11-16 Steven K. Libutti Methods for treating tumors using antiangiogenic compounds
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
US6416777B1 (en) 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
DE60040876D1 (de) 1999-10-21 2009-01-02 Alcon Inc Medikamentenzuführeinrichtung
MXPA02002376A (es) 1999-10-21 2002-08-28 Alcon Universal Ltd Entrega de droga al sub-tenon-.
US6267954B1 (en) * 1999-11-24 2001-07-31 Universite De Paris V Rene-Descartes Intraocular transplantation of encapsulated cells
AU780634C (en) * 2000-02-11 2006-02-23 Genvec, Inc. Gene Therapy for treating ocular-related disorders
ATE404140T1 (de) * 2000-08-30 2008-08-15 Univ Johns Hopkins Vorrichtung zur intraokularen wirkstoffverabreichung
US6697668B2 (en) * 2001-01-25 2004-02-24 Iomed, Inc. Ocular iontophoretic device and method for using the same
US6546284B2 (en) * 2001-01-25 2003-04-08 Iomed, Inc. Fluid retention assembly for an iontophoretic delivery device and associated method for preparing the same
US7181287B2 (en) * 2001-02-13 2007-02-20 Second Sight Medical Products, Inc. Implantable drug delivery device
US6875165B2 (en) * 2001-02-22 2005-04-05 Retinalabs, Inc. Method of radiation delivery to the eye
WO2002089767A1 (en) 2001-05-03 2002-11-14 Massachusetts Eye And Ear Infirmary Implantable drug delivery device and use thereof
DE60239868D1 (de) 2001-06-12 2011-06-09 Univ Johns Hopkins Med Reservoirvorrichtung für die intraokulare arzneimittelabgabe
US7031776B2 (en) * 2001-06-29 2006-04-18 Optobionics Methods for improving damaged retinal cell function
US20050033202A1 (en) * 2001-06-29 2005-02-10 Chow Alan Y. Mechanically activated objects for treatment of degenerative retinal disease
DE10133870A1 (de) * 2001-07-12 2003-02-06 Chris P Lohmann Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge
ES2271301T3 (es) * 2001-07-23 2007-04-16 Alcon, Inc. Dispositivo de suministro de farmaco oftalmico.
CN1203814C (zh) 2001-07-23 2005-06-01 爱尔康公司 眼部药物输送装置
CN1536998A (zh) 2001-08-01 2004-10-13 Ĭ��ר�����޹�˾ 用于治疗眼病的整联蛋白抑制剂
WO2003092665A2 (en) * 2002-05-02 2003-11-13 Massachusetts Eye And Ear Infirmary Ocular drug delivery systems and use thereof
AU2003279055A1 (en) * 2002-09-29 2004-04-19 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US20060167435A1 (en) * 2003-02-18 2006-07-27 Adamis Anthony P Transscleral drug delivery device and related methods
AU2004237774B2 (en) * 2003-05-02 2009-09-10 Surmodics, Inc. Implantable controlled release bioactive agent delivery device
US8246974B2 (en) * 2003-05-02 2012-08-21 Surmodics, Inc. Medical devices and methods for producing the same
KR20060031618A (ko) 2003-06-10 2006-04-12 엔에스진 에이/에스 뉴블라스틴 분비 증진 방법
JP2007526019A (ja) * 2003-07-10 2007-09-13 アルコン，インコーポレイティド 眼科用薬物送達デバイス
AU2004274026A1 (en) * 2003-09-18 2005-03-31 Macusight, Inc. Transscleral delivery
CA2543189A1 (en) 2003-10-20 2005-05-06 Nsgene A/S In vivo gene therapy of parkinson's disease
US20050136095A1 (en) * 2003-12-22 2005-06-23 Brian Levy Drug delivery device with suture ring
IL159818A0 (en) * 2004-01-12 2004-06-20 Nulens Ltd Intraocular structure
US7803103B2 (en) * 2005-02-11 2010-09-28 Neovista Inc. Methods and apparatus for intraocular brachytherapy
US7563222B2 (en) * 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
US7744520B2 (en) * 2004-02-12 2010-06-29 Neovista, Inc. Method and apparatus for intraocular brachytherapy
JP5010464B2 (ja) 2004-03-30 2012-08-29 エヌエスジーン・アクティーゼルスカブ 成長因子、ＮｓＧ３３の治療上の使用
WO2006002366A2 (en) * 2004-06-24 2006-01-05 Surmodics, Inc. Biodegradable ocular devices, methods and systems
US20060110428A1 (en) * 2004-07-02 2006-05-25 Eugene Dejuan Methods and devices for the treatment of ocular conditions
WO2006013462A2 (en) * 2004-07-30 2006-02-09 Nsgene A/S Growth factors nsg28, nsg30, and nsg32
WO2006023130A2 (en) * 2004-08-12 2006-03-02 Surmodics, Inc. Biodegradable controlled release bioactive agent delivery device
US8246569B1 (en) 2004-08-17 2012-08-21 California Institute Of Technology Implantable intraocular pressure drain
MX2007004030A (es) * 2004-10-04 2008-01-14 Cellgate Inc Analogos de poliamina como agentes terapeuticos para enfermedades oculares.
CA2597590A1 (en) * 2005-02-09 2006-08-17 Macusight, Inc. Formulations for ocular treatment
US8663639B2 (en) * 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
TW200640443A (en) * 2005-02-23 2006-12-01 Alcon Inc Methods for treating ocular angiogenesis, retinal edema, retinal ischemia, and diabetic retinopathy using selective RTK inhibitors
US20060233858A1 (en) * 2005-03-08 2006-10-19 Allergan, Inc. Systems and methods providing targeted intraocular drug delivery
US20070077270A1 (en) * 2005-03-28 2007-04-05 Clemson University Delivery devices and methods for long-term, targeted delivery of therapeutic agents to the eye and ear
JP2008533995A (ja) 2005-04-01 2008-08-28 エヌエスジーン・アクティーゼルスカブ ヒト不死化神経前駆細胞系
CA2601864A1 (en) * 2005-04-08 2006-10-19 Surmodics, Inc. Sustained release implants and methods for subretinal delivery of bioactive agents to treat or prevent retinal disease
US20060258994A1 (en) * 2005-05-12 2006-11-16 Avery Robert L Implantable delivery device for administering pharmacological agents to an internal portion of a body
EP1883446B8 (en) * 2005-05-17 2017-11-15 Gloria Therapeutics Sarl An implantable therapy system for treating a living being with an active factor
US8309057B2 (en) * 2005-06-10 2012-11-13 The Invention Science Fund I, Llc Methods for elevating neurotrophic agents
AU2006272497B2 (en) 2005-07-27 2012-07-19 University Of Florida Research Foundation, Inc. Small compounds that correct protein misfolding and uses thereof
MX2008006379A (es) 2005-11-29 2009-03-03 Smithkline Beecham Corp Metodo de tratamiento.
EP1971288B1 (en) 2005-12-30 2013-02-13 Neurotech USA, Inc. Micronized device for the delivery of biologically active molecules and methods of use thereof
CN101389295B (zh) * 2006-01-17 2010-11-10 纽镜有限公司 眼球内药物分配器
WO2007092620A2 (en) 2006-02-09 2007-08-16 Macusight, Inc. Stable formulations, and methods of their preparation and use
DE602007012417D1 (de) * 2006-03-14 2011-03-24 Univ Southern California Mems-Vorrichtung zur Wirkstofffreisetzung
US8222271B2 (en) * 2006-03-23 2012-07-17 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions
EP2091481A2 (en) * 2006-12-18 2009-08-26 Alcon Research, Ltd. Devices and methods for ophthalmic drug delivery
US20080265343A1 (en) * 2007-04-26 2008-10-30 International Business Machines Corporation Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
ES2425769T5 (es) 2007-12-20 2017-07-28 University Of Southern California Aparato para la administración de agentes terapéuticos
DK2240220T3 (en) 2008-01-03 2016-08-01 Univ Southern California Implantable devices for drug AND APPARATUS FOR refilling DEVICES
US9849238B2 (en) 2008-05-08 2017-12-26 Minipumps, Llc Drug-delivery pump with intelligent control
WO2009137780A2 (en) * 2008-05-08 2009-11-12 Replenish Pumps, Llc Implantable pumps and cannulas therefor
CA2723723C (en) 2008-05-08 2019-06-25 Replenish Pumps, Llc Implantable drug-delivery devices, and apparatus and methods for filling the devices
CN102202708B (zh) 2008-05-08 2015-01-21 迷你泵有限责任公司 药物输送泵及其制造方法
BRPI0913380A2 (pt) 2008-06-04 2015-11-24 Neovista Inc sistema portátil de liberação de radiação para o avanço de um fio de fonte de radiação
EP2389435B1 (en) 2009-01-23 2015-11-04 NsGene A/S Improved cell lines and their use in encapsulated cell biodelivery
EP2389191A2 (en) 2009-01-23 2011-11-30 NsGene A/S Expression of neuropeptides in mammalian cells
US8632511B2 (en) * 2009-05-06 2014-01-21 Alcon Research, Ltd. Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device
IN2012DN00352A (enExample) 2009-06-16 2015-08-21 Bikam Pharmaceuticals Inc
JP5758388B2 (ja) 2009-08-18 2015-08-05 ミニパンプス， エルエルシー 適応制御を有する電解質薬物送達ポンプ
WO2011039648A1 (en) 2009-09-30 2011-04-07 Glaxo Wellcome Manufacturing Pte Ltd. Methods of administration and treatment
US8177747B2 (en) * 2009-12-22 2012-05-15 Alcon Research, Ltd. Method and apparatus for drug delivery
EP2621403B1 (en) 2010-09-27 2015-03-18 NsGene A/S Implantable cell device with supportive and radial diffusive scaffolding
AU2011307488B2 (en) 2010-10-01 2015-08-20 Hoba Therapeutics Aps Use of meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
CN106431988A (zh) 2011-06-14 2017-02-22 比卡姆药品公司 视蛋白结合配体、组合物及使用方法
CN104105501B (zh) 2011-09-05 2017-10-20 霍巴治疗公司 异常性疼痛、痛觉过敏、自发性疼痛、和幻痛的治疗
CA2856703A1 (en) 2011-10-19 2013-04-25 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
JP6126118B2 (ja) 2011-11-30 2017-05-10 ビカム ファーマスーティカルス，インコーポレイテッド オプシン結合性リガンド、組成物、及び使用方法
EP2785178B1 (en) 2011-12-01 2019-05-01 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
RU2494711C1 (ru) * 2012-05-18 2013-10-10 Федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения и социального развития Российской Федерации Способ хирургического лечения прогрессирующей и осложненной миопии
JP6549482B2 (ja) 2012-06-01 2019-07-24 サーモディクス，インコーポレイテッド バルーンカテーテルをコーティングするための装置および方法
US9827401B2 (en) 2012-06-01 2017-11-28 Surmodics, Inc. Apparatus and methods for coating medical devices
US11090468B2 (en) 2012-10-25 2021-08-17 Surmodics, Inc. Apparatus and methods for coating medical devices
WO2014160884A1 (en) 2013-03-28 2014-10-02 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
US9925219B2 (en) 2013-09-11 2018-03-27 Neurotech Usa, Inc. Encapsulated cell therapy cartridge
SG11201703726XA (en) 2014-11-10 2017-06-29 Forsight Vision4 Inc Expandable drug delivery devices and method of use
CN109195556B (zh) 2016-04-05 2021-03-26 弗赛特影像4股份有限公司 可植入眼睛药物递送装置
WO2020112816A1 (en) 2018-11-29 2020-06-04 Surmodics, Inc. Apparatus and methods for coating medical devices
US11819590B2 (en) 2019-05-13 2023-11-21 Surmodics, Inc. Apparatus and methods for coating medical devices
EP4051192B1 (en) * 2019-11-01 2025-07-30 Neurotech USA, Inc. Analyte diffusive implantable device
AU2021225926A1 (en) 2020-02-26 2022-10-20 Case Western Reserve University Compositions and methods for treating misfolded protein ocular disorders
US12496612B2 (en) 2021-01-08 2025-12-16 Surmodics, Inc. Coating application system and methods for coating rotatable medical devices

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116798A (ja) * 1974-08-01 1976-02-10 Mihairoichi Kurasunofu Mihairu Jinkosuishotai
US5266562A (en) * 1987-11-19 1993-11-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Anti-inflammatory agents
US5521215A (en) * 1989-11-07 1996-05-28 Ramot University Authority For Applied Research And Industrial Development Ltd. NMDA-blocking pharmaceuticals
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5382514A (en) * 1992-03-31 1995-01-17 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services In vivo angiogenesis assay
US5178635A (en) * 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
US5279298A (en) * 1992-11-20 1994-01-18 The Johns Hopkins University Method and apparatus to identify and treat neovascular membranes in the eye
US5443505A (en) * 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5550050A (en) * 1994-04-15 1996-08-27 Cytotherapeutics, Inc. Method for implanting encapsulated cells in a host
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5472436A (en) * 1994-07-26 1995-12-05 Fremstad; Daria A. Ocular appliance for delivering medication

Also Published As

Publication number Publication date
DE69733357D1 (de) 2005-06-30
JP2010265314A (ja) 2010-11-25
AU2541997A (en) 1997-10-10
WO1997034586A2 (en) 1997-09-25
US5904144A (en) 1999-05-18
EP0927024B1 (en) 2005-05-25
JP4740077B2 (ja) 2011-08-03
ES2242223T3 (es) 2005-11-01
EP0927024B8 (en) 2005-08-31
EP1574209B1 (en) 2010-03-03
DE69733357T2 (de) 2006-02-02
EP1574209A1 (en) 2005-09-14
JP2000507854A (ja) 2000-06-27
CA2264895A1 (en) 1997-09-25
WO1997034586A3 (en) 1997-10-23
AU716400B2 (en) 2000-02-24
DK1574209T3 (da) 2010-05-31
DE69739792D1 (de) 2010-04-15
ATE296087T1 (de) 2005-06-15
ATE459335T1 (de) 2010-03-15
JP2006342185A (ja) 2006-12-21
EP0927024A2 (en) 1999-07-07
CA2264895C (en) 2008-05-27
ES2342075T3 (es) 2010-07-01

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