JP2000507854A - 眼疾患を処置するための装置および方法 - Google Patents

眼疾患を処置するための装置および方法

Info

Publication number
JP2000507854A
JP2000507854A JP9533777A JP53377797A JP2000507854A JP 2000507854 A JP2000507854 A JP 2000507854A JP 9533777 A JP9533777 A JP 9533777A JP 53377797 A JP53377797 A JP 53377797A JP 2000507854 A JP2000507854 A JP 2000507854A
Authority
JP
Japan
Prior art keywords
eye
capsule
biologically active
active molecule
factors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP9533777A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000507854A5 (enExample
Inventor
ディー． スペアー，ピーター
ピー． ハマング，ジョセフ
ビートグ，イー．エドワード
ジー． トシアラス，ウイリアム
Original Assignee
サイトセラピュウティックス，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by サイトセラピュウティックス，インコーポレイテッド filed Critical サイトセラピュウティックス，インコーポレイテッド
Publication of JP2000507854A publication Critical patent/JP2000507854A/ja
Publication of JP2000507854A5 publication Critical patent/JP2000507854A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • A61K2035/128—Immunoprotecting barriers, e.g. jackets, diffusion chambers capsules, e.g. microcapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP9533777A 1996-03-22 1997-03-24 眼疾患を処置するための装置および方法 Withdrawn JP2000507854A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/620,982 US5904144A (en) 1996-03-22 1996-03-22 Method for treating ophthalmic diseases
US08/620,982 1996-03-22
PCT/US1997/004701 WO1997034586A2 (en) 1996-03-22 1997-03-24 Device and method for treating ophthalmic diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006248673A Division JP4740077B2 (ja) 1996-03-22 2006-09-13 眼疾患を処置するための装置および方法

Publications (2)

Publication Number Publication Date
JP2000507854A true JP2000507854A (ja) 2000-06-27
JP2000507854A5 JP2000507854A5 (enExample) 2004-12-02

Family

ID=24488233

Family Applications (3)

Application Number Title Priority Date Filing Date
JP9533777A Withdrawn JP2000507854A (ja) 1996-03-22 1997-03-24 眼疾患を処置するための装置および方法
JP2006248673A Expired - Lifetime JP4740077B2 (ja) 1996-03-22 2006-09-13 眼疾患を処置するための装置および方法
JP2010184490A Withdrawn JP2010265314A (ja) 1996-03-22 2010-08-19 眼疾患を処置するための装置および方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2006248673A Expired - Lifetime JP4740077B2 (ja) 1996-03-22 2006-09-13 眼疾患を処置するための装置および方法
JP2010184490A Withdrawn JP2010265314A (ja) 1996-03-22 2010-08-19 眼疾患を処置するための装置および方法

Country Status (10)

Country Link
US (1) US5904144A (enExample)
EP (2) EP0927024B8 (enExample)
JP (3) JP2000507854A (enExample)
AT (2) ATE296087T1 (enExample)
AU (1) AU716400B2 (enExample)
CA (1) CA2264895C (enExample)
DE (2) DE69733357T2 (enExample)
DK (2) DK0927024T3 (enExample)
ES (2) ES2242223T3 (enExample)
WO (1) WO1997034586A2 (enExample)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003524621A (ja) * 1999-04-06 2003-08-19 ニューロテック ソシエテ アノニム カプセル化された細胞ベースの送達のためのプラットホーム細胞株としてのａｒｐｅ−１９
JP2004538056A (ja) * 2001-07-12 2004-12-24 ペー ローマン クリス ドライアイの治療のためのインサート
JP2007515488A (ja) * 2003-12-22 2007-06-14 ボーシュ アンド ローム インコーポレイティド 縫合環を有する薬物送達デバイス
JP2007517575A (ja) * 2004-01-12 2007-07-05 ニューレンズ・リミテッド 眼球壁碇留固定装置
JP2008515800A (ja) * 2004-10-04 2008-05-15 セルゲイト， インコーポレイテッド 眼科疾患の処置剤としてのポリアミン類似化合物
JP2008539996A (ja) * 2005-05-17 2008-11-20 エヌエスゲーネ・アクティーゼルスカブ 活性因子によって生物を治療する移植可能な療法システム
JP2008543382A (ja) * 2005-06-10 2008-12-04 シーリート エルエルシー 神経の維持・再生のための方法およびシステム
JP2009522269A (ja) * 2005-12-30 2009-06-11 ニューロテック ユーエスエー， インコーポレイテッド 生物活性分子の送達のための微粒子化デバイスおよびその使用方法
JP2010513542A (ja) * 2006-12-18 2010-04-30 アルコン リサーチ， リミテッド 眼用薬物送達のためのデバイスおよび方法
JP4881959B2 (ja) * 2006-01-17 2012-02-22 ニューレンズ・リミテッド 眼内薬物ディスペンサ
JP2022553849A (ja) * 2019-11-01 2022-12-26 ニューロテック ユーエスエー，インコーポレイティド 埋め込み可能な検体拡散の機器のためのシステム、装置、機器及び方法
US12629242B2 (en) 2020-11-02 2026-05-19 Neurotech Usa, Inc. System, apparatuses, devices, and methods for packaging an analyte diffusive implantable device

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299895B1 (en) * 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
KR100514277B1 (ko) 1996-09-13 2005-09-13 유겐가이샤 사이센딴이가꾸겡꾸쇼 신경 영양 인자의 안과용 조성물, 시신경 기능 장애 치료제 및 시신경 기능 장애 치료 방법
DE19718826A1 (de) * 1997-05-05 1998-11-12 Marion S Dr Eckmiller Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung
WO1999013868A1 (en) * 1997-09-17 1999-03-25 Alcon Laboratories, Inc. Methods for treating ocular diseases
US7282482B2 (en) * 1998-04-08 2007-10-16 The Regents Of The University Of California NGF for the prevention of demyelination in the nervous system
EP1154691A4 (en) * 1999-01-05 2004-07-07 Massachusetts Eye & Ear Infirm TARGETED ADMINISTRATION OF REGULATED RELEASE MEDICINE TO RETINA AND CHOROID THROUGH SCLEROTIC
US20070071734A1 (en) * 1999-04-06 2007-03-29 Weng Tao ARPE-19 as platform cell line for encapsulated cell-based delivery
CA2372699A1 (en) * 1999-05-07 2000-11-16 Steven K. Libutti Methods for treating tumors using antiangiogenic compounds
US6416777B1 (en) 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
ES2240180T3 (es) 1999-10-21 2005-10-16 Alcon Inc. Administracion sub-tenon de medicamentos.
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
ATE414494T1 (de) 1999-10-21 2008-12-15 Alcon Inc Medikamentenzuführeinrichtung
US6267954B1 (en) * 1999-11-24 2001-07-31 Universite De Paris V Rene-Descartes Intraocular transplantation of encapsulated cells
WO2001058494A2 (en) * 2000-02-11 2001-08-16 Genvec, Inc. Gene therapy for treating ocular-related disorders
ATE404140T1 (de) * 2000-08-30 2008-08-15 Univ Johns Hopkins Vorrichtung zur intraokularen wirkstoffverabreichung
US6697668B2 (en) * 2001-01-25 2004-02-24 Iomed, Inc. Ocular iontophoretic device and method for using the same
US6546284B2 (en) * 2001-01-25 2003-04-08 Iomed, Inc. Fluid retention assembly for an iontophoretic delivery device and associated method for preparing the same
US7181287B2 (en) * 2001-02-13 2007-02-20 Second Sight Medical Products, Inc. Implantable drug delivery device
US6875165B2 (en) * 2001-02-22 2005-04-05 Retinalabs, Inc. Method of radiation delivery to the eye
WO2002089767A1 (en) 2001-05-03 2002-11-14 Massachusetts Eye And Ear Infirmary Implantable drug delivery device and use thereof
JP4677538B2 (ja) 2001-06-12 2011-04-27 ジョンズ ホプキンズ ユニヴァーシティ スクール オヴ メディシン 眼内薬物送達のためのリザーバデバイス
US7031776B2 (en) 2001-06-29 2006-04-18 Optobionics Methods for improving damaged retinal cell function
US20050033202A1 (en) * 2001-06-29 2005-02-10 Chow Alan Y. Mechanically activated objects for treatment of degenerative retinal disease
EP1385452B1 (en) * 2001-07-23 2006-09-13 Alcon, Inc. Ophthalmic drug delivery device
DE60217679T2 (de) 2001-07-23 2007-10-25 Alcon Inc. Vorrichtung zur freisetzung eines ophthalmischen arzneimittels
ES2243744T3 (es) * 2001-08-01 2005-12-01 Merck Patent Gmbh Inhibidores de integrina para el tratamiento de enfermedades de los ojos.
WO2003092665A2 (en) * 2002-05-02 2003-11-13 Massachusetts Eye And Ear Infirmary Ocular drug delivery systems and use thereof
CA2689424A1 (en) * 2002-09-29 2004-04-08 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US20060167435A1 (en) * 2003-02-18 2006-07-27 Adamis Anthony P Transscleral drug delivery device and related methods
ATE476960T1 (de) 2003-05-02 2010-08-15 Surmodics Inc System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges
US8246974B2 (en) * 2003-05-02 2012-08-21 Surmodics, Inc. Medical devices and methods for producing the same
ATE423134T1 (de) 2003-06-10 2009-03-15 Nsgene As Verbesserte sezernierung von neublastin
KR20060082792A (ko) * 2003-07-10 2006-07-19 알콘, 인코퍼레이티드 안과용 약물 전달 장치
JP2007505932A (ja) * 2003-09-18 2007-03-15 マクサイト， インコーポレイテッド 経強膜送達
ES2342397T3 (es) 2003-10-20 2010-07-06 Nsgene A/S Vector virico para su uso en terapia genica in vivo de la enfermedad de parkinson.
US7744520B2 (en) * 2004-02-12 2010-06-29 Neovista, Inc. Method and apparatus for intraocular brachytherapy
US7563222B2 (en) * 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
CN1950397B (zh) 2004-03-30 2012-05-16 Ns基因公司 生长因子NsG33的治疗用途
WO2006002366A2 (en) * 2004-06-24 2006-01-05 Surmodics, Inc. Biodegradable ocular devices, methods and systems
US20060110428A1 (en) 2004-07-02 2006-05-25 Eugene Dejuan Methods and devices for the treatment of ocular conditions
US20090136552A1 (en) * 2004-07-30 2009-05-28 Mette Gronborg Growth factors nsg28, nsg30, and nsg32
US20060034891A1 (en) * 2004-08-12 2006-02-16 Laurie Lawin Biodegradable controlled release bioactive agent delivery device
US8246569B1 (en) 2004-08-17 2012-08-21 California Institute Of Technology Implantable intraocular pressure drain
US8663639B2 (en) * 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
WO2006086750A1 (en) * 2005-02-09 2006-08-17 Macusight, Inc. Liquid formulations for treatment of diseases or conditions
TW200640443A (en) * 2005-02-23 2006-12-01 Alcon Inc Methods for treating ocular angiogenesis, retinal edema, retinal ischemia, and diabetic retinopathy using selective RTK inhibitors
US20060233858A1 (en) * 2005-03-08 2006-10-19 Allergan, Inc. Systems and methods providing targeted intraocular drug delivery
US20070077270A1 (en) * 2005-03-28 2007-04-05 Clemson University Delivery devices and methods for long-term, targeted delivery of therapeutic agents to the eye and ear
CA2603391A1 (en) 2005-04-01 2006-10-05 Nsgene A/S A human immortalised neural precursor cell line
CN101180086A (zh) * 2005-04-08 2008-05-14 苏尔莫迪克斯公司 用于经视网膜下递送的持续释放植入物
US20060258994A1 (en) * 2005-05-12 2006-11-16 Avery Robert L Implantable delivery device for administering pharmacological agents to an internal portion of a body
CA2616537A1 (en) 2005-07-27 2007-02-01 University Of Florida Research Foundation, Inc. Small compounds that correct protein misfolding and uses thereof
CA2629648A1 (en) 2005-11-15 2007-05-24 Neovista Inc. Methods and apparatus for intraocular brachytherapy
PL1968594T3 (pl) 2005-11-29 2011-03-31 Glaxosmithkline Llc Leczenie zaburzeń neowaskularyzacyjnych oka, takich jak zwyrodnienie plamki żółtej, rozszerzenie naczyń siatkówki w zespole Hippla i Lindaua, zapalenie błony naczyniowej oka i obrzęk plamki
US8492400B2 (en) 2006-02-09 2013-07-23 Santen Pharmaceutical Co., Ltd. Stable formulations, and methods of their preparation and use
EP2319558B1 (en) * 2006-03-14 2014-05-21 University Of Southern California Mems device for delivery of therapeutic agents
CN101443004B (zh) * 2006-03-23 2013-03-06 参天制药株式会社 用于与血管通透性有关的疾病或病症的制剂
US20080265343A1 (en) * 2007-04-26 2008-10-30 International Business Machines Corporation Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
EP2666510B1 (en) 2007-12-20 2017-10-18 University Of Southern California Apparatus for controlled delivery of therapeutic agents
EP2727616B1 (en) 2008-01-03 2017-04-26 University Of Southern California Implantable drug-delivery devices, and apparatus and methods for refilling the devices
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
EP2323716B1 (en) 2008-05-08 2015-03-04 MiniPumps, LLC Drug-delivery pumps
CN102202719B (zh) * 2008-05-08 2014-11-26 迷你泵有限责任公司 可植入泵和用于可植入泵的插管
WO2009137777A2 (en) * 2008-05-08 2009-11-12 Replenish Pumps, Llc Implantable drug-delivery devices, and apparatus and methods for filling the devices
CA2724327A1 (en) 2008-06-04 2009-12-10 Neovista, Inc. Handheld radiation delivery system for advancing a radiation source wire
EP2389191A2 (en) 2009-01-23 2011-11-30 NsGene A/S Expression of neuropeptides in mammalian cells
EP2389435B1 (en) 2009-01-23 2015-11-04 NsGene A/S Improved cell lines and their use in encapsulated cell biodelivery
US8372036B2 (en) * 2009-05-06 2013-02-12 Alcon Research, Ltd. Multi-layer heat assembly for a drug delivery device
IN2012DN00352A (enExample) 2009-06-16 2015-08-21 Bikam Pharmaceuticals Inc
KR101697388B1 (ko) 2009-08-18 2017-01-17 미니펌프스, 엘엘씨 적응 제어기를 갖춘 전해 약품 운반 펌프
US20120232102A1 (en) 2009-09-30 2012-09-13 Chun-Fang Xu Methods Of Administration And Treatment
US8177747B2 (en) * 2009-12-22 2012-05-15 Alcon Research, Ltd. Method and apparatus for drug delivery
JP5852655B2 (ja) 2010-09-27 2016-02-03 エヌエスジーン・アクティーゼルスカブＮｓＧｅｎｅ Ａ／Ｓ 支持・放射状拡散スカフォールディングを備える埋込み型細胞デバイス
KR101886029B1 (ko) 2010-10-01 2018-08-07 호바 세라퓨틱스 에이피에스 무해자극통증, 통각과민증, 자발통증 및 헛통증의 치료를 위한 메테오린의 용도
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9133082B2 (en) 2011-06-14 2015-09-15 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
EP2753347B1 (en) 2011-09-05 2016-08-03 NsGene A/S Treatment of allodynia, hyperalgsia, spontaneous pain, and phantom pain
WO2013058809A1 (en) 2011-10-19 2013-04-25 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
WO2013082000A1 (en) 2011-11-30 2013-06-06 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
WO2013081642A1 (en) 2011-12-01 2013-06-06 Bikam Pharmaceuticals, Inc. Opsin-binding ligands, compositions and methods of use
RU2494711C1 (ru) * 2012-05-18 2013-10-10 Федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения и социального развития Российской Федерации Способ хирургического лечения прогрессирующей и осложненной миопии
US9827401B2 (en) 2012-06-01 2017-11-28 Surmodics, Inc. Apparatus and methods for coating medical devices
MX351261B (es) 2012-06-01 2017-10-06 Surmodics Inc Aparato y método para recubrir catéteres con globo.
US11090468B2 (en) 2012-10-25 2021-08-17 Surmodics, Inc. Apparatus and methods for coating medical devices
AU2014241163B2 (en) 2013-03-28 2018-09-27 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
AU2014318846A1 (en) * 2013-09-11 2016-03-10 Neurotech Usa, Inc. Encapsulated cell therapy cartridge
JP7037360B2 (ja) 2014-11-10 2022-03-16 フォーサイト・ビジョン フォー・インコーポレーテッド 拡張可能な薬物送達デバイス
BR112018070383A2 (pt) 2016-04-05 2019-02-05 Forsight Vision4 Inc dispositivos para aplicação de fármaco oculares implantáveis
WO2020112816A1 (en) 2018-11-29 2020-06-04 Surmodics, Inc. Apparatus and methods for coating medical devices
US11819590B2 (en) 2019-05-13 2023-11-21 Surmodics, Inc. Apparatus and methods for coating medical devices
AU2021225926A1 (en) 2020-02-26 2022-10-20 Case Western Reserve University Compositions and methods for treating misfolded protein ocular disorders
US12496612B2 (en) 2021-01-08 2025-12-16 Surmodics, Inc. Coating application system and methods for coating rotatable medical devices

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116798A (ja) * 1974-08-01 1976-02-10 Mihairoichi Kurasunofu Mihairu Jinkosuishotai
US5266562A (en) * 1987-11-19 1993-11-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Anti-inflammatory agents
US5521215A (en) * 1989-11-07 1996-05-28 Ramot University Authority For Applied Research And Industrial Development Ltd. NMDA-blocking pharmaceuticals
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5382514A (en) * 1992-03-31 1995-01-17 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services In vivo angiogenesis assay
US5178635A (en) * 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
US5279298A (en) * 1992-11-20 1994-01-18 The Johns Hopkins University Method and apparatus to identify and treat neovascular membranes in the eye
US5443505A (en) * 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5550050A (en) * 1994-04-15 1996-08-27 Cytotherapeutics, Inc. Method for implanting encapsulated cells in a host
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5472436A (en) * 1994-07-26 1995-12-05 Fremstad; Daria A. Ocular appliance for delivering medication

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003524621A (ja) * 1999-04-06 2003-08-19 ニューロテック ソシエテ アノニム カプセル化された細胞ベースの送達のためのプラットホーム細胞株としてのａｒｐｅ−１９
JP2004538056A (ja) * 2001-07-12 2004-12-24 ペー ローマン クリス ドライアイの治療のためのインサート
JP2007515488A (ja) * 2003-12-22 2007-06-14 ボーシュ アンド ローム インコーポレイティド 縫合環を有する薬物送達デバイス
JP2007517575A (ja) * 2004-01-12 2007-07-05 ニューレンズ・リミテッド 眼球壁碇留固定装置
JP2008515800A (ja) * 2004-10-04 2008-05-15 セルゲイト， インコーポレイテッド 眼科疾患の処置剤としてのポリアミン類似化合物
US9364427B2 (en) 2005-05-17 2016-06-14 Nsgene A/S Implantable therapy system for treating a living being with an active factor
JP2008539996A (ja) * 2005-05-17 2008-11-20 エヌエスゲーネ・アクティーゼルスカブ 活性因子によって生物を治療する移植可能な療法システム
JP2008543382A (ja) * 2005-06-10 2008-12-04 シーリート エルエルシー 神経の維持・再生のための方法およびシステム
KR101326611B1 (ko) 2005-06-10 2013-11-08 디 인벤션 사이언스 펀드 원, 엘엘씨 신경의 유지 및 재생을 위한 방법 및 시스템
JP2009522269A (ja) * 2005-12-30 2009-06-11 ニューロテック ユーエスエー， インコーポレイテッド 生物活性分子の送達のための微粒子化デバイスおよびその使用方法
JP4881959B2 (ja) * 2006-01-17 2012-02-22 ニューレンズ・リミテッド 眼内薬物ディスペンサ
JP2010513542A (ja) * 2006-12-18 2010-04-30 アルコン リサーチ， リミテッド 眼用薬物送達のためのデバイスおよび方法
JP2022553849A (ja) * 2019-11-01 2022-12-26 ニューロテック ユーエスエー，インコーポレイティド 埋め込み可能な検体拡散の機器のためのシステム、装置、機器及び方法
JP7783807B2 (ja) 2019-11-01 2025-12-10 ニューロテック ユーエスエー，インコーポレイティド 埋め込み可能な検体拡散の機器のためのシステム、装置、機器及び方法
US12629242B2 (en) 2020-11-02 2026-05-19 Neurotech Usa, Inc. System, apparatuses, devices, and methods for packaging an analyte diffusive implantable device

Also Published As

Publication number Publication date
ES2342075T3 (es) 2010-07-01
EP0927024B8 (en) 2005-08-31
DE69739792D1 (de) 2010-04-15
DE69733357T2 (de) 2006-02-02
CA2264895C (en) 2008-05-27
EP0927024A2 (en) 1999-07-07
WO1997034586A2 (en) 1997-09-25
JP2010265314A (ja) 2010-11-25
ATE296087T1 (de) 2005-06-15
EP1574209A1 (en) 2005-09-14
EP1574209B1 (en) 2010-03-03
DE69733357D1 (de) 2005-06-30
JP2006342185A (ja) 2006-12-21
EP0927024B1 (en) 2005-05-25
ES2242223T3 (es) 2005-11-01
JP4740077B2 (ja) 2011-08-03
AU716400B2 (en) 2000-02-24
CA2264895A1 (en) 1997-09-25
WO1997034586A3 (en) 1997-10-23
DK0927024T3 (da) 2005-08-29
US5904144A (en) 1999-05-18
ATE459335T1 (de) 2010-03-15
DK1574209T3 (da) 2010-05-31
AU2541997A (en) 1997-10-10

Similar Documents

Publication Publication Date Title
JP4740077B2 (ja) 眼疾患を処置するための装置および方法
US6299895B1 (en) Device and method for treating ophthalmic diseases
JP4954374B2 (ja) カプセル化された細胞ベースの送達のためのプラットホーム細胞株としてのａｒｐｅ−１９
JP4524230B2 (ja) 遺伝的に改変された細胞を含む生体適合性免疫隔離カプセル
US9265814B2 (en) Micronized device for the delivery of biologically active molecules and methods of use thereof
US20160120695A1 (en) Use of pedf in an encapsulated cell-based delivery system
US6500449B2 (en) Intraocular transplantation of encapsulated cells
US20240335562A1 (en) Sustainable ocular cell-mediated intraocular delivery of cellular therapeutics for treatment of ocular diseases or disorders
WO1994001124A1 (en) METHOD OF TREATING OPHTHALMIC DISORDERS USING TGF-$g(b)
AU708536B2 (en) System and method for delivery of cytokines using encapsulated cytokine-secreting cells
CN101351230A (zh) 用于投递gdnf的可植入式生物相容性免疫绝缘性媒介物

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20040305

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20040305

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20060314

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20060607

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20060724

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20060913

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20060911

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20070206

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070531

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20070614

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20070802

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20080423

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090708

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090716

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091225

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20100826