DK0923568T5 - Hidtil ukendte benzofuran-4-carboxamider - Google Patents

Hidtil ukendte benzofuran-4-carboxamider

Info

Publication number
DK0923568T5
DK0923568T5 DK97942858T DK97942858T DK0923568T5 DK 0923568 T5 DK0923568 T5 DK 0923568T5 DK 97942858 T DK97942858 T DK 97942858T DK 97942858 T DK97942858 T DK 97942858T DK 0923568 T5 DK0923568 T5 DK 0923568T5
Authority
DK
Denmark
Prior art keywords
carboxamides
benzofuran
newly known
newly
substituted
Prior art date
Application number
DK97942858T
Other languages
Danish (da)
English (en)
Other versions
DK0923568T3 (da
Inventor
Hermann Amschler
Ulrich Thibaut
Dietrich Haefner
Dieter Flockerzi
Armin Hatzelmann
Christian Schudt
Rolf Beume
Hans-Peter Kley
Wolf-Ruediger Ulrich
Beate Schmidt
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK0923568T3 publication Critical patent/DK0923568T3/da
Publication of DK0923568T5 publication Critical patent/DK0923568T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Table Devices Or Equipment (AREA)
DK97942858T 1996-08-19 1997-08-13 Hidtil ukendte benzofuran-4-carboxamider DK0923568T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19633052 1996-08-19
PCT/EP1997/004398 WO1998007715A1 (en) 1996-08-19 1997-08-13 Novel benzofuran-4-carboxamides

Publications (2)

Publication Number Publication Date
DK0923568T3 DK0923568T3 (da) 2003-04-07
DK0923568T5 true DK0923568T5 (da) 2003-11-03

Family

ID=7802799

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97942858T DK0923568T5 (da) 1996-08-19 1997-08-13 Hidtil ukendte benzofuran-4-carboxamider

Country Status (11)

Country Link
US (1) US6211203B1 (enExample)
EP (1) EP0923568B9 (enExample)
JP (1) JP4309475B2 (enExample)
AT (1) ATE229516T1 (enExample)
AU (1) AU4454597A (enExample)
CY (1) CY2458B1 (enExample)
DE (1) DE69717827T2 (enExample)
DK (1) DK0923568T5 (enExample)
ES (1) ES2188983T4 (enExample)
PT (1) PT923568E (enExample)
WO (1) WO1998007715A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE239004T1 (de) * 1996-05-20 2003-05-15 Darwin Discovery Ltd Benzofuran carboxamide und ihre therapeutische anwendung
WO1999040085A1 (en) * 1998-02-09 1999-08-12 Darwin Discovery Limited Benzofuran-4-carboxamides and their therapeutic use
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
PT1086096E (pt) 1998-06-10 2003-12-31 Altana Pharma Ag Benzamidas com substituintes etra-hidrofuraniloxi como inibidores da fosfodiesterase 4
WO2000027802A1 (en) * 1998-11-12 2000-05-18 Ariad Pharmaceuticals, Inc. Bicyclic signal transduction inhibitors, compositions containing them & uses thereof
DE19924340A1 (de) 1999-05-27 2000-11-30 Basf Ag Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
CA2715683A1 (en) 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
US7153824B2 (en) 2003-04-01 2006-12-26 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP2275095A3 (en) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
EP2382975A3 (en) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
AU2009290474A1 (en) 2008-09-11 2010-03-18 Pfizer Inc. Heteroaryls amide derivatives and their use as glucokinase activators
AR074760A1 (es) * 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
EP2604604A1 (en) * 2009-03-11 2013-06-19 Pfizer Inc Benzofuranyl derivatives used as glucokinase inhibitors
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
ES2526124T3 (es) * 2010-06-16 2015-01-07 Cymabay Therapeutics, Inc. Agonistas del receptor GPR120 y sus usos
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
TWI717656B (zh) * 2017-11-10 2021-02-01 大陸商江蘇恒瑞醫藥股份有限公司 苯並呋喃衍生物的製備方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59410119D1 (de) * 1993-07-02 2002-06-20 Byk Gulden Lomberg Chem Fab Fluoralkoxy substituierte benzamide und ihre verwendung als zyklisch-nukleotid phosphodiesterase-inhibitoren
DK0772610T3 (da) * 1994-07-22 2001-01-29 Byk Gulden Lomberg Chem Fab Dihydrobenzofuraner
DK0771794T3 (da) * 1995-05-19 2006-09-11 Kyowa Hakko Kogyo Kk Oxygenholdige heterocykliske forbindelser
CZ292443B6 (cs) * 1995-12-05 2003-09-17 Darwin Discovery Limited Benzofuransulfonamid, farmaceutický prostředek jej obsahující a jeho použití
ATE239004T1 (de) * 1996-05-20 2003-05-15 Darwin Discovery Ltd Benzofuran carboxamide und ihre therapeutische anwendung

Also Published As

Publication number Publication date
EP0923568B1 (en) 2002-12-11
JP4309475B2 (ja) 2009-08-05
DE69717827D1 (de) 2003-01-23
WO1998007715A1 (en) 1998-02-26
EP0923568B9 (en) 2003-08-13
CY2458B1 (en) 2005-06-03
WO1998007715A9 (en) 1999-04-29
AU4454597A (en) 1998-03-06
ES2188983T3 (es) 2003-07-01
ES2188983T4 (es) 2004-06-01
PT923568E (pt) 2003-04-30
JP2000516932A (ja) 2000-12-19
EP0923568A1 (en) 1999-06-23
DK0923568T3 (da) 2003-04-07
US6211203B1 (en) 2001-04-03
ATE229516T1 (de) 2002-12-15
DE69717827T2 (de) 2003-09-04

Similar Documents

Publication Publication Date Title
DK0923568T3 (da) Hidtil ukendte benzofuran-4-carboxamider
EA199700061A1 (ru) Способ получения силденафила
ATE260103T1 (de) Ortho-anthranilamide derivate als antikoagulantien
ES2193252T3 (es) Quinolonas y su uso terapeutico.
DE69618231D1 (de) TETRAHYDROIMIDAZOPYRIDOINDOLDIONE ALS cGMP SPEZIFISCHE PDE HEMMER
MX9700557A (es) Dihidrobenzofuranos.
DE69516866D1 (de) Stereochemische wortmanninderivate
ATE315560T1 (de) Polyhydroxylierte heterocyclische derivate als antikoagulanten
MX9205678A (es) Heteroarilaminas como nuevos inhibidores de la acetilcolinesterasa.
DE69709938D1 (de) N-benzylpiperidin- und tetrahydropyridin-derivate
DE69722656D1 (de) Bicyclische arylcarboxamide und ihre therapeutische verwendung
EP0932606A4 (en) Inhibitors of prenyl transferases
DE59100597D1 (de) Verwendung von N-Alkyl-lactamen als Kristallisationsinhibitoren.
ATE233252T1 (de) Substituierte dihydrobenzofurane als pde- hemmstoffe
ES2071325T3 (es) Derivados de 4-alquilimidazol.
ES2060818T3 (es) Derivados de indol, benzofurano y benzotiofeno sustituidos como inhibidores de la 5-lipooxigenasa.
WO2003018549A3 (en) Bicyclic compounds as inhibitors of chemokine binding to us28
DK0696278T3 (da) Herbicidtvirkende substituerede 1-phenyl- eller 1-pyridinylbenzotriazoler
ES2104174T3 (es) Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.
NZ333854A (en) Intermediates for the preparation of 2-imidazoline-5-ones
EA200100864A1 (ru) Способ получения 1,4,7,10-тетраазациклододекана
PT1104419E (pt) Derivados de azabicicloheptano substituidos no azoto sua preparacao e utilizacao
ES2173634T3 (es) Compuestos heterociclicos que presentan actividad inhibidora de mmp y tnf.
DE59711147D1 (de) Neue Imidazo- und Oxazolopyridine als Phosphodiesterase Inhibitoren.
ATE135352T1 (de) 3-keto-hmg-coa reduktase-inhibitoren