DE69618231D1 - TETRAHYDROIMIDAZOPYRIDOINDOLDIONE ALS cGMP SPEZIFISCHE PDE HEMMER - Google Patents

TETRAHYDROIMIDAZOPYRIDOINDOLDIONE ALS cGMP SPEZIFISCHE PDE HEMMER

Info

Publication number
DE69618231D1
DE69618231D1 DE69618231T DE69618231T DE69618231D1 DE 69618231 D1 DE69618231 D1 DE 69618231D1 DE 69618231 T DE69618231 T DE 69618231T DE 69618231 T DE69618231 T DE 69618231T DE 69618231 D1 DE69618231 D1 DE 69618231D1
Authority
DE
Germany
Prior art keywords
tetrahydroimidazopyridoindoldione
pde inhibitors
specific pde
cgmp specific
cgmp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69618231T
Other languages
English (en)
Other versions
DE69618231T2 (de
Inventor
Claude-Marie Daugan
Frederic Labaudiniere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Icos Corp
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Publication of DE69618231D1 publication Critical patent/DE69618231D1/de
Application granted granted Critical
Publication of DE69618231T2 publication Critical patent/DE69618231T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DE69618231T 1995-07-14 1996-07-11 TETRAHYDROIMIDAZOPYRIDOINDOLDIONE ALS cGMP SPEZIFISCHE PDE HEMMER Expired - Fee Related DE69618231T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514473.9A GB9514473D0 (en) 1995-07-14 1995-07-14 Chemical compounds
PCT/EP1996/003023 WO1996032003A2 (en) 1995-07-14 1996-07-11 Tetrahydroimidazopyridoindolediones and their use as medicaments

Publications (2)

Publication Number Publication Date
DE69618231D1 true DE69618231D1 (de) 2002-01-31
DE69618231T2 DE69618231T2 (de) 2002-08-22

Family

ID=10777704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69618231T Expired - Fee Related DE69618231T2 (de) 1995-07-14 1996-07-11 TETRAHYDROIMIDAZOPYRIDOINDOLDIONE ALS cGMP SPEZIFISCHE PDE HEMMER

Country Status (13)

Country Link
US (3) US6001847A (de)
EP (1) EP0859778B1 (de)
JP (1) JP4012246B2 (de)
CN (1) CN1095841C (de)
AT (1) ATE211139T1 (de)
AU (1) AU702548B2 (de)
BR (1) BR9609503A (de)
CA (1) CA2226759A1 (de)
DE (1) DE69618231T2 (de)
ES (1) ES2170252T3 (de)
GB (1) GB9514473D0 (de)
MX (1) MX9800415A (de)
WO (1) WO1996032003A2 (de)

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US20110027226A1 (en) * 2007-08-22 2011-02-03 4Sc Ag Indolopyridines as inhibitors of the kinesin spindle protein (eg5)
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Also Published As

Publication number Publication date
EP0859778B1 (de) 2001-12-19
CN1195350A (zh) 1998-10-07
EP0859778A2 (de) 1998-08-26
ES2170252T3 (es) 2002-08-01
WO1996032003A2 (en) 1996-10-17
US6001847A (en) 1999-12-14
DE69618231T2 (de) 2002-08-22
JP4012246B2 (ja) 2007-11-21
MX9800415A (es) 1998-04-30
BR9609503A (pt) 2000-03-08
US6143757A (en) 2000-11-07
WO1996032003A3 (en) 1997-01-03
CN1095841C (zh) 2002-12-11
ATE211139T1 (de) 2002-01-15
JPH11509517A (ja) 1999-08-24
US6218400B1 (en) 2001-04-17
CA2226759A1 (en) 1996-10-17
AU6613896A (en) 1996-10-30
GB9514473D0 (en) 1995-09-13
AU702548B2 (en) 1999-02-25

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee