PT923568E - Novas benzofuran-4-carboxamidas - Google Patents

Novas benzofuran-4-carboxamidas

Info

Publication number
PT923568E
PT923568E PT97942858T PT97942858T PT923568E PT 923568 E PT923568 E PT 923568E PT 97942858 T PT97942858 T PT 97942858T PT 97942858 T PT97942858 T PT 97942858T PT 923568 E PT923568 E PT 923568E
Authority
PT
Portugal
Prior art keywords
carboxamides
new benzofuran
benzofuran
new
substituted
Prior art date
Application number
PT97942858T
Other languages
English (en)
Portuguese (pt)
Inventor
Hans-Peter Kley
Christian Schudt
Rolf Beume
Dietrich Hafner
Ulrich Thibaut
Wolf-Rudiger Ulrich
Dieter Flockerzi
Beate Schmidt
Armin Hatzelmann
Hermann Amschler
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PT923568E publication Critical patent/PT923568E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Table Devices Or Equipment (AREA)
PT97942858T 1996-08-19 1997-08-13 Novas benzofuran-4-carboxamidas PT923568E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19633052 1996-08-19

Publications (1)

Publication Number Publication Date
PT923568E true PT923568E (pt) 2003-04-30

Family

ID=7802799

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97942858T PT923568E (pt) 1996-08-19 1997-08-13 Novas benzofuran-4-carboxamidas

Country Status (11)

Country Link
US (1) US6211203B1 (enExample)
EP (1) EP0923568B9 (enExample)
JP (1) JP4309475B2 (enExample)
AT (1) ATE229516T1 (enExample)
AU (1) AU4454597A (enExample)
CY (1) CY2458B1 (enExample)
DE (1) DE69717827T2 (enExample)
DK (1) DK0923568T5 (enExample)
ES (1) ES2188983T4 (enExample)
PT (1) PT923568E (enExample)
WO (1) WO1998007715A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199802386T2 (xx) * 1996-05-20 1999-02-22 Darwin Discovery Limited Benzofuran karboksamidler ve bunlar�n terap�tik kullan�m�.
CA2317478A1 (en) * 1998-02-09 1999-08-12 Darwin Discovery Limited Benzofuran-4-carboxamides and their therapeutic use
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
US6303789B1 (en) * 1998-06-10 2001-10-16 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzamides with tetrahydrofuranyloxy substitutents as phosphodiesterase 4 inhibitors
WO2000027802A1 (en) * 1998-11-12 2000-05-18 Ariad Pharmaceuticals, Inc. Bicyclic signal transduction inhibitors, compositions containing them & uses thereof
DE19924340A1 (de) 1999-05-27 2000-11-30 Basf Ag Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
CA2715683A1 (en) 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
EA200501548A1 (ru) 2003-04-01 2006-02-24 Апплайд Резеч Системз Арс Холдинг Н.В. Ингибиторы фосфодиэстераз при бесплодии
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
PE20110303A1 (es) 2008-09-11 2011-05-21 Pfizer Derivados de heteroaril acetamidas como activadores de glucoquinasa
AR074760A1 (es) * 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
ES2427279T3 (es) 2009-03-11 2013-10-29 Pfizer Inc. Derivados de benzofuranilo usados como inhibidores de glucocinasa
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
CA2801182A1 (en) * 2010-06-16 2011-12-22 Metabolex, Inc. Gpr120 receptor agonists and uses thereof
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
WO2019091450A1 (zh) 2017-11-10 2019-05-16 江苏恒瑞医药股份有限公司 一种苯并呋喃衍生物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59410119D1 (de) * 1993-07-02 2002-06-20 Byk Gulden Lomberg Chem Fab Fluoralkoxy substituierte benzamide und ihre verwendung als zyklisch-nukleotid phosphodiesterase-inhibitoren
NZ290420A (en) * 1994-07-22 1999-01-28 Byk Gulden Lomberg Chem Fab Phenyl or pyridyl-amide substituted dihydro benzofurans; medicaments
AU705690B2 (en) * 1995-05-19 1999-05-27 Kyowa Hakko Kogyo Co. Ltd. Oxygen-containing heterocyclic compounds
CN1100773C (zh) * 1995-12-05 2003-02-05 达尔文发现有限公司 苯并呋喃羧酸胺和磺酰胺
TR199802386T2 (xx) * 1996-05-20 1999-02-22 Darwin Discovery Limited Benzofuran karboksamidler ve bunlar�n terap�tik kullan�m�.

Also Published As

Publication number Publication date
EP0923568A1 (en) 1999-06-23
EP0923568B9 (en) 2003-08-13
AU4454597A (en) 1998-03-06
CY2458B1 (en) 2005-06-03
ATE229516T1 (de) 2002-12-15
ES2188983T4 (es) 2004-06-01
US6211203B1 (en) 2001-04-03
ES2188983T3 (es) 2003-07-01
WO1998007715A1 (en) 1998-02-26
DK0923568T5 (da) 2003-11-03
DE69717827T2 (de) 2003-09-04
DE69717827D1 (de) 2003-01-23
DK0923568T3 (da) 2003-04-07
JP2000516932A (ja) 2000-12-19
JP4309475B2 (ja) 2009-08-05
WO1998007715A9 (en) 1999-04-29
EP0923568B1 (en) 2002-12-11

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