ATE229516T1 - Benzofuran-4-carboxamide - Google Patents

Benzofuran-4-carboxamide

Info

Publication number
ATE229516T1
ATE229516T1 AT97942858T AT97942858T ATE229516T1 AT E229516 T1 ATE229516 T1 AT E229516T1 AT 97942858 T AT97942858 T AT 97942858T AT 97942858 T AT97942858 T AT 97942858T AT E229516 T1 ATE229516 T1 AT E229516T1
Authority
AT
Austria
Prior art keywords
benzofuran
carboxamide
substituted
optionally
flourine
Prior art date
Application number
AT97942858T
Other languages
German (de)
English (en)
Inventor
Wolf-Ruediger Ulrich
Dieter Flockerzi
Beate Schmidt
Ulrich Thibaut
Armin Hatzelmann
Christian Schudt
Rolf Beume
Dietrich Haefner
Hans-Peter Kley
Hermann Amschler
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE229516T1 publication Critical patent/ATE229516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Table Devices Or Equipment (AREA)
AT97942858T 1996-08-19 1997-08-13 Benzofuran-4-carboxamide ATE229516T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19633052 1996-08-19
PCT/EP1997/004398 WO1998007715A1 (en) 1996-08-19 1997-08-13 Novel benzofuran-4-carboxamides

Publications (1)

Publication Number Publication Date
ATE229516T1 true ATE229516T1 (de) 2002-12-15

Family

ID=7802799

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97942858T ATE229516T1 (de) 1996-08-19 1997-08-13 Benzofuran-4-carboxamide

Country Status (11)

Country Link
US (1) US6211203B1 (enExample)
EP (1) EP0923568B9 (enExample)
JP (1) JP4309475B2 (enExample)
AT (1) ATE229516T1 (enExample)
AU (1) AU4454597A (enExample)
CY (1) CY2458B1 (enExample)
DE (1) DE69717827T2 (enExample)
DK (1) DK0923568T5 (enExample)
ES (1) ES2188983T4 (enExample)
PT (1) PT923568E (enExample)
WO (1) WO1998007715A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972936A (en) * 1996-05-20 1999-10-26 Darwin Discover Limited Benzofuran carboxamides and their therapeutic use
AU2529799A (en) * 1998-02-09 1999-08-23 Darwin Discovery Limited Benzofuran-4-carboxamides and their therapeutic use
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
WO1999064414A1 (de) * 1998-06-10 1999-12-16 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzamide mit tetrahydrofuranyloxy-substituenten als inhibitoren der phosphodiesterase 4
WO2000027802A1 (en) * 1998-11-12 2000-05-18 Ariad Pharmaceuticals, Inc. Bicyclic signal transduction inhibitors, compositions containing them & uses thereof
DE19924340A1 (de) 1999-05-27 2000-11-30 Basf Ag Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
EP1671651B1 (en) 1999-08-21 2009-11-11 Nycomed GmbH Synergistic combination of pumafentrine and salmeterol
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
CA2625153A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
EP2382975A3 (en) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
JP2010502722A (ja) 2006-09-08 2010-01-28 ブレインセルス，インコーポレイティド ４−アシルアミノピリジン誘導体を含む組み合わせ
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
NZ591366A (en) 2008-09-11 2012-05-25 Pfizer Heteroaryls amide derivatives and their use as glucokinase activators
AR074760A1 (es) * 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2010103437A1 (en) * 2009-03-11 2010-09-16 Pfizer Inc. Benzofuranyl derivatives used as glucokinase inhibitors
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
CA2801182A1 (en) * 2010-06-16 2011-12-22 Metabolex, Inc. Gpr120 receptor agonists and uses thereof
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
MX395591B (es) * 2017-11-10 2025-03-25 Jiangsu Hengrui Medicine Co Metodo para preparar derivado de benzofurano

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ290266B6 (cs) * 1993-07-02 2002-06-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituované benzamidy, způsob jejich výroby a farmaceutické prostředky s jejich obsahem
ES2152414T3 (es) * 1994-07-22 2001-02-01 Byk Gulden Lomberg Chem Fab Dihidrobenzofuranos.
WO1996036624A1 (en) * 1995-05-19 1996-11-21 Kyowa Hakko Kogyo Co., Ltd. Oxygen-containing heterocyclic compounds
JP2000501411A (ja) * 1995-12-05 2000-02-08 ダーウィン・ディスカバリー・リミテッド ベンゾフランカルボキサミドおよびスルホンアミド
US5972936A (en) * 1996-05-20 1999-10-26 Darwin Discover Limited Benzofuran carboxamides and their therapeutic use

Also Published As

Publication number Publication date
DE69717827T2 (de) 2003-09-04
PT923568E (pt) 2003-04-30
JP2000516932A (ja) 2000-12-19
ES2188983T3 (es) 2003-07-01
EP0923568B1 (en) 2002-12-11
ES2188983T4 (es) 2004-06-01
AU4454597A (en) 1998-03-06
WO1998007715A1 (en) 1998-02-26
EP0923568A1 (en) 1999-06-23
CY2458B1 (en) 2005-06-03
DE69717827D1 (de) 2003-01-23
US6211203B1 (en) 2001-04-03
JP4309475B2 (ja) 2009-08-05
EP0923568B9 (en) 2003-08-13
DK0923568T5 (da) 2003-11-03
DK0923568T3 (da) 2003-04-07
WO1998007715A9 (en) 1999-04-29

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