ATE229516T1 - Benzofuran-4-carboxamide - Google Patents

Benzofuran-4-carboxamide

Info

Publication number
ATE229516T1
ATE229516T1 AT97942858T AT97942858T ATE229516T1 AT E229516 T1 ATE229516 T1 AT E229516T1 AT 97942858 T AT97942858 T AT 97942858T AT 97942858 T AT97942858 T AT 97942858T AT E229516 T1 ATE229516 T1 AT E229516T1
Authority
AT
Austria
Prior art keywords
benzofuran
carboxamide
substituted
optionally
flourine
Prior art date
Application number
AT97942858T
Other languages
German (de)
English (en)
Inventor
Wolf-Ruediger Ulrich
Dieter Flockerzi
Beate Schmidt
Ulrich Thibaut
Armin Hatzelmann
Christian Schudt
Rolf Beume
Dietrich Haefner
Hans-Peter Kley
Hermann Amschler
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE229516T1 publication Critical patent/ATE229516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Table Devices Or Equipment (AREA)
AT97942858T 1996-08-19 1997-08-13 Benzofuran-4-carboxamide ATE229516T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19633052 1996-08-19
PCT/EP1997/004398 WO1998007715A1 (en) 1996-08-19 1997-08-13 Novel benzofuran-4-carboxamides

Publications (1)

Publication Number Publication Date
ATE229516T1 true ATE229516T1 (de) 2002-12-15

Family

ID=7802799

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97942858T ATE229516T1 (de) 1996-08-19 1997-08-13 Benzofuran-4-carboxamide

Country Status (11)

Country Link
US (1) US6211203B1 (enExample)
EP (1) EP0923568B9 (enExample)
JP (1) JP4309475B2 (enExample)
AT (1) ATE229516T1 (enExample)
AU (1) AU4454597A (enExample)
CY (1) CY2458B1 (enExample)
DE (1) DE69717827T2 (enExample)
DK (1) DK0923568T5 (enExample)
ES (1) ES2188983T4 (enExample)
PT (1) PT923568E (enExample)
WO (1) WO1998007715A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0100042A3 (en) * 1996-05-20 2003-01-28 Darwin Discovery Ltd Cambridge Benzofuran carboxamides medicaments containing the same and their therapeutic use
AU2529799A (en) * 1998-02-09 1999-08-23 Darwin Discovery Limited Benzofuran-4-carboxamides and their therapeutic use
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
EP1086096B1 (de) * 1998-06-10 2003-07-23 ALTANA Pharma AG Benzamide mit tetrahydrofuranyloxy-substituenten als inhibitoren der phosphodiesterase 4
CA2345459A1 (en) * 1998-11-12 2000-05-18 Regine Bohacek Bicyclic signal transduction inhibitors, compositions containing them & uses thereof
DE19924340A1 (de) 1999-05-27 2000-11-30 Basf Ag Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
SI1212089T1 (sl) 1999-08-21 2006-08-31 Altana Pharma Ag Sinergisticna kombinacija roflumilasta in salmeterola
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
EP1942879A1 (en) 2005-10-31 2008-07-16 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
KR101258331B1 (ko) 2008-09-11 2013-04-26 화이자 인코포레이티드 헤테로아릴 아미드 유도체 및 글루코키나제 활성화제로서의 그의 용도
AR074760A1 (es) * 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
UA99882C2 (uk) 2009-03-11 2012-10-10 Пфайзер Інк. Похідні бензофуранілу, фармацевтична композиція та спосіб лікування захворювань (варіанти)
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
CA2801182A1 (en) * 2010-06-16 2011-12-22 Metabolex, Inc. Gpr120 receptor agonists and uses thereof
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
JP7295105B6 (ja) * 2017-11-10 2023-07-24 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 ベンゾフラン誘導体の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI0706513T1 (en) * 1993-07-02 2002-10-31 Altana Pharma Ag Fluoroalkoxy-substituted benzamides and their use as cyclic nucleotide phosphodiesterase inhibitors
MX9700557A (es) * 1994-07-22 1997-12-31 Byk Gulden Lomberg Chem Fab Dihidrobenzofuranos.
DE69636086T2 (de) * 1995-05-19 2006-11-30 Kyowa Hakko Kogyo Co., Ltd. Sauerstoff enthaltende heterocyclische verbindungen
CN1100773C (zh) * 1995-12-05 2003-02-05 达尔文发现有限公司 苯并呋喃羧酸胺和磺酰胺
HUP0100042A3 (en) * 1996-05-20 2003-01-28 Darwin Discovery Ltd Cambridge Benzofuran carboxamides medicaments containing the same and their therapeutic use

Also Published As

Publication number Publication date
ES2188983T4 (es) 2004-06-01
WO1998007715A9 (en) 1999-04-29
WO1998007715A1 (en) 1998-02-26
JP2000516932A (ja) 2000-12-19
EP0923568A1 (en) 1999-06-23
CY2458B1 (en) 2005-06-03
DE69717827T2 (de) 2003-09-04
PT923568E (pt) 2003-04-30
US6211203B1 (en) 2001-04-03
EP0923568B1 (en) 2002-12-11
DE69717827D1 (de) 2003-01-23
ES2188983T3 (es) 2003-07-01
AU4454597A (en) 1998-03-06
JP4309475B2 (ja) 2009-08-05
DK0923568T5 (da) 2003-11-03
EP0923568B9 (en) 2003-08-13
DK0923568T3 (da) 2003-04-07

Similar Documents

Publication Publication Date Title
DE69717827D1 (de) Benzofuran-4-carboxamide
EA199700061A1 (ru) Способ получения силденафила
ATE211139T1 (de) Tetrahydroimidazopyridoindoldione als cgmp spezifische pde hemmer
MX9700557A (es) Dihidrobenzofuranos.
ATE260103T1 (de) Ortho-anthranilamide derivate als antikoagulantien
PT841929E (pt) Quinolonas e sua utilizacao terapeutica
ATE215371T1 (de) Naphthyl substituierte benzimidazolderivate als antikoagulantien
MX9205678A (es) Heteroarilaminas como nuevos inhibidores de la acetilcolinesterasa.
IT8919316A0 (it) Benzoderivati di composti eterociclici contenenti azoto.
DE59100597D1 (de) Verwendung von N-Alkyl-lactamen als Kristallisationsinhibitoren.
DE69722656D1 (de) Bicyclische arylcarboxamide und ihre therapeutische verwendung
EP0932606A4 (en) Inhibitors of prenyl transferases
DE69719358D1 (de) Substituierte dihydrobenzofurane als pde-hemmstoffe
DK0696278T3 (da) Herbicidtvirkende substituerede 1-phenyl- eller 1-pyridinylbenzotriazoler
EA200200381A1 (ru) Тетрагидротиопиранфталазиноновые производные в качестве ингибиторов pde4
DE69632936D1 (de) Verwendung von Pyrrolverbindungen als Antifouling-Wirkstoff
ES2179254T3 (es) 1-poliarilpirazoles plaguicidas.
NZ333854A (en) Intermediates for the preparation of 2-imidazoline-5-ones
ES2173634T3 (es) Compuestos heterociclicos que presentan actividad inhibidora de mmp y tnf.
DE59711147D1 (de) Neue Imidazo- und Oxazolopyridine als Phosphodiesterase Inhibitoren.
DE69025817D1 (de) 3-Keto-HMG-CoA Reduktase-Inhibitoren
EA199800597A1 (ru) Производные морфина с анальгетической активностью
SU1746666A1 (ru) Замещенные 3-аминометиленпирролидин-2,4-дионы, обладающие противосудорожной активностью
SU1786802A1 (ru) 2,4-ДИМЕТИЛ-9-ОКСИПИРИДО[1,2-a]ПИРИМИДИНИЙХЛОРИД, ОБЛАДАЮЩИЙ АНТИДЕПРЕССИВНОЙ АКТИВНОСТЬЮ
UY24326A1 (es) Nuevas piperidinas.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0923568

Country of ref document: EP

REN Ceased due to non-payment of the annual fee