DK0859596T3 - Vækstfaktorholdige gelformuleringer - Google Patents

Vækstfaktorholdige gelformuleringer

Info

Publication number
DK0859596T3
DK0859596T3 DK96935936T DK96935936T DK0859596T3 DK 0859596 T3 DK0859596 T3 DK 0859596T3 DK 96935936 T DK96935936 T DK 96935936T DK 96935936 T DK96935936 T DK 96935936T DK 0859596 T3 DK0859596 T3 DK 0859596T3
Authority
DK
Denmark
Prior art keywords
gel formulations
growth factor
gel
containing gel
topical
Prior art date
Application number
DK96935936T
Other languages
Danish (da)
English (en)
Inventor
John Cini
Amy Finkenur
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Application granted granted Critical
Publication of DK0859596T3 publication Critical patent/DK0859596T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1808Epidermal growth factor [EGF] urogastrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
DK96935936T 1995-10-06 1996-09-24 Vækstfaktorholdige gelformuleringer DK0859596T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/539,898 US5705485A (en) 1987-09-18 1995-10-06 Gel formulations containing growth factors
PCT/US1996/015288 WO1997012601A2 (fr) 1995-10-06 1996-09-24 Formulations de gel contenant des facteurs de croissance

Publications (1)

Publication Number Publication Date
DK0859596T3 true DK0859596T3 (da) 2002-03-04

Family

ID=24153118

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96935936T DK0859596T3 (da) 1995-10-06 1996-09-24 Vækstfaktorholdige gelformuleringer

Country Status (19)

Country Link
US (1) US5705485A (fr)
EP (1) EP0859596B1 (fr)
JP (1) JP4001382B2 (fr)
KR (1) KR100444417B1 (fr)
CN (1) CN1142791C (fr)
AT (1) ATE209900T1 (fr)
AU (1) AU706806B2 (fr)
BR (1) BR9610790A (fr)
CA (1) CA2234235C (fr)
CZ (1) CZ294676B6 (fr)
DE (1) DE69617723T2 (fr)
DK (1) DK0859596T3 (fr)
ES (1) ES2167611T3 (fr)
HU (1) HU223880B1 (fr)
NO (1) NO981539L (fr)
PL (1) PL187174B1 (fr)
PT (1) PT859596E (fr)
WO (1) WO1997012601A2 (fr)
ZA (1) ZA968398B (fr)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9815708B1 (pt) * 1998-03-07 2010-10-19 composição tópica para tratar lesões cutáneas.
US20030147860A1 (en) * 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
ATE363292T1 (de) * 1998-09-04 2007-06-15 Scios Inc Hydrogelzusammensetzungen mit kontrollierter freigabe von wachstumsfaktoren
US6057280A (en) 1998-11-19 2000-05-02 Huish Detergents, Inc. Compositions containing α-sulfofatty acid esters and methods of making and using the same
DE19925519A1 (de) * 1999-06-04 2000-12-07 Lohmann Therapie Syst Lts Wundauflage zur gesteuerten Abgabe von Wirkstoff an Wunden und Verfahren zu ihrer Herstellung
AU5624500A (en) * 1999-06-18 2001-01-09 Collaborative Group, Ltd., The Hyaluronic acid microspheres for sustained gene transfer
US8188043B2 (en) * 1999-07-28 2012-05-29 The Board Of Trustees Of The Leland Stanford Jr. University Nicotine in therapeutic angiogenesis and vasculogenesis
WO2001034214A1 (fr) 1999-11-09 2001-05-17 Denki Kagaku Kogyo Kabushiki Kaisha Utilisation de derives de cellulose solubles rendus difficilement solubles dans l'eau et methode de preparation de ces derives
DE10048260A1 (de) * 2000-09-29 2002-04-11 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Aminoguanidin und/oder dessen Derivaten und Strukturanaloga zur Hautaufhellung von Altersflecken und/oder zur Verhinderung der Hautbräunung, insbesondere der durch UV-Strahlung hervorgerufenen Hautbräunung
US6703039B2 (en) * 2000-12-06 2004-03-09 Bausch & Lomb Incorporated Reversible gelling system for ocular drug delivery
CA2436076A1 (fr) * 2001-01-26 2002-08-01 Genetix Pharmaceuticals, Inc. Methodes et compositions permettant de stimuler l'angiogenese
DE10140623A1 (de) * 2001-08-18 2003-03-06 Nawa Heilmittel Gmbh Pharmazeutisches Präparat zur Behandlung von Wunden
US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US7037504B2 (en) * 2001-10-23 2006-05-02 Waratah Pharmaceuticals, Inc. Epidermal growth factor protein and gene, and methods of use therefor
DE60323943D1 (de) 2002-02-21 2008-11-20 Encelle Inc Immobilisierte bioaktive hydrogel matrizen für oberflächenbeschichtungen
US20080086792A1 (en) 2006-10-13 2008-04-17 Thomas Charles Kuracina Method and apparatus for diverting sweat, liquid, moisture or the like from an eye
US20030220632A1 (en) * 2002-05-23 2003-11-27 Wolfgang Strasser Method of using gel sheets for laser treatment
ES2358645T3 (es) * 2002-09-16 2011-05-12 Agennix Incorporated Composiciones de lactoferrina y métodos de tratamiento de la úlcera diabética.
BRPI0413381A (pt) * 2003-08-07 2006-10-17 Allergan Inc composições para liberação de compostos terapêuticos nos olhos e processos para fabricação e uso das mesmas
US8062661B2 (en) 2003-12-11 2011-11-22 Teikoku Pharma Usa, Inc. Methods and compositions for treating skin wounds
CN100411615C (zh) * 2003-12-12 2008-08-20 上海第二医科大学附属瑞金医院 氨基胍对难愈创面的防治作用
WO2005077402A1 (fr) * 2004-02-11 2005-08-25 Virchow Biotech Private Limited Formulations de gel a base de miel
WO2006015302A1 (fr) * 2004-07-29 2006-02-09 X-Sten, Corp. Dispositifs de modification de ligament vertebral
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
EP1811935B1 (fr) 2004-09-28 2016-03-30 Atrium Medical Corporation Gel thermodurcissable et son procede de fabrication
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
BRPI0613284A2 (pt) * 2005-06-17 2010-12-28 Genentech Inc métodos de aceleração de cicatrização de ferida
WO2007013100A1 (fr) * 2005-07-26 2007-02-01 Virchow Biotech Private Limited Formulation de gel comprenant le facteur de croissance dérivé des plaquettes
EP3228265A3 (fr) 2005-07-29 2018-05-23 Vertos Medical, Inc. Dispositifs d'excision percutanée de tissus
US20070055263A1 (en) * 2005-07-29 2007-03-08 X-Sten Corp. Tools for Percutaneous Spinal Ligament Decompression and Device for Supporting Same
FR2891149B1 (fr) 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
US9278161B2 (en) * 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
DE102005055275A1 (de) * 2005-11-17 2007-05-24 Ursapharm Arzneimittel Gmbh & Co. Kg Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung
KR100687281B1 (ko) * 2005-11-30 2007-02-27 한국과학기술연구원 생리 활성 물질이 결합된 조직 재생용 주입형 온도 감응성플루로닉 유도체 하이드로겔 및 이의 제조 방법
KR100742313B1 (ko) * 2006-03-21 2007-07-24 퓨리메드 주식회사 신규한 혈소판 유래 성장 인자(pdgf) b 폴리펩타이드및 이의 유전자
US7942830B2 (en) 2006-05-09 2011-05-17 Vertos Medical, Inc. Ipsilateral approach to minimally invasive ligament decompression procedure
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
CN101528239B (zh) * 2006-10-26 2013-03-13 千寿制药株式会社 眼科用水性液体药剂
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
EP2114268A4 (fr) * 2007-02-12 2010-03-03 Vertos Medical Inc Dispositifs et procédés d'excision tissulaire
US20090118709A1 (en) * 2007-11-06 2009-05-07 Vertos Medical, Inc. A Delaware Corporation Tissue Excision Tool, Kits and Methods of Using the Same
JP5582711B2 (ja) * 2008-09-25 2014-09-03 株式会社エー・アイ・システムプロダクト ローション状の塗薬
USD619252S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
USD621939S1 (en) 2008-10-23 2010-08-17 Vertos Medical, Inc. Tissue modification device
USD610259S1 (en) 2008-10-23 2010-02-16 Vertos Medical, Inc. Tissue modification device
USD611146S1 (en) 2008-10-23 2010-03-02 Vertos Medical, Inc. Tissue modification device
USD619253S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
PT2480204E (pt) * 2009-09-22 2014-01-22 Vlife Sciences Technologies Pvt Ltd Formulação tópica para úlceras do pé diabético
EP2593141B1 (fr) 2010-07-16 2018-07-04 Atrium Medical Corporation Composition et procédés destinés à modifier la vitesse d'hydrolyse de substances vulcanisées à base d'huile
EP2729219A4 (fr) * 2011-07-06 2015-04-01 Orf Líftaekni Hf Procédé d'utilisation d'un facteur de croissance d'origine non végétale stabilisé pour les soins de la peau
CA2854160A1 (fr) 2011-11-02 2013-05-10 Halscion, Inc. Methodes et compositions utilisees pour le traitement des plaies
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US9422497B2 (en) 2012-09-21 2016-08-23 Exxonmobil Research And Engineering Company Synthetic lubricant basestocks and methods of preparation thereof
US10376562B2 (en) 2013-03-15 2019-08-13 The Jackson Laboratory Methods for promoting wound healing and hair growth comprising GDNF administration
SG11201507429TA (en) 2013-03-15 2015-10-29 Genentech Inc Il-22 polypeptides and il-22 fc fusion proteins and methods of use
US9675537B2 (en) 2014-06-30 2017-06-13 Johnson & Johnson Consumer Inc. Hair growth composition and method
JP6871855B2 (ja) * 2014-10-14 2021-05-19 サムエル リンチ, 創傷を処置するための組成物
WO2017035280A1 (fr) * 2015-08-24 2017-03-02 Nugene, Inc. Pansements et aides à la cicatrisation de lésion cutanée
WO2017143438A1 (fr) * 2016-02-23 2017-08-31 Matripharm International Inc. Composition à double vitesse de libération et à forte charge médicamenteuse
US20220088274A1 (en) * 2017-05-18 2022-03-24 The Board Of Trustees Of The Leland Stanford Junior University Targeted in Situ Therapeutic Delivery of Secreted Factors from Stem Cells for Treatment of Damaged Tissue
CA3088763A1 (fr) 2018-01-26 2019-08-01 Genentech, Inc. Compositions et methodes d'utilisation
CR20200327A (es) 2018-01-26 2020-11-05 Genentech Inc Proteínas de fusión fc il-22 y métodos de uso
AU2019226085A1 (en) 2018-02-21 2020-09-17 Genentech, Inc. Dosing for treatment with IL-22 Fc fusion proteins
CN114601959A (zh) * 2020-11-23 2022-06-10 山东融元康医疗科技有限公司 一种医用皮肤护理敷料及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190361B (it) * 1985-05-30 1988-02-16 Zambon Spa Composizione farmaceutica in crema per uso dermale ed oftalmico
US4717717A (en) * 1986-11-05 1988-01-05 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
NZ222413A (en) * 1986-11-05 1991-06-25 Ethicon Inc Compositions containing a polypeptide growth factor and a water-soluble cellulose polymer stabiliser
US5124316A (en) * 1986-11-14 1992-06-23 President And Fellows Of Harvard College Method for periodontal regeneration
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
MX9203083A (es) * 1991-06-21 1994-08-31 Genetics Inst Formulaciones farmaceuticas de proteinas osteogenicas.
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
AU3062392A (en) * 1991-11-04 1993-06-07 Novo Nordisk A/S Pdgf gel formulation
JP3102655B2 (ja) * 1991-12-27 2000-10-23 住友製薬株式会社 超音波制御による薬物放出製剤

Also Published As

Publication number Publication date
US5705485A (en) 1998-01-06
DE69617723T2 (de) 2002-05-08
PL326064A1 (en) 1998-08-17
CA2234235C (fr) 2002-05-14
AU7370796A (en) 1997-04-28
WO1997012601A2 (fr) 1997-04-10
AU706806B2 (en) 1999-06-24
ATE209900T1 (de) 2001-12-15
HU223880B1 (hu) 2005-02-28
NO981539D0 (no) 1998-04-03
PL187174B1 (pl) 2004-05-31
KR100444417B1 (ko) 2004-11-03
JP4001382B2 (ja) 2007-10-31
WO1997012601A3 (fr) 1997-05-01
HUP9803002A2 (hu) 1999-04-28
BR9610790A (pt) 1999-07-13
CN1142791C (zh) 2004-03-24
CZ294676B6 (cs) 2005-02-16
CZ102498A3 (cs) 1999-08-11
EP0859596B1 (fr) 2001-12-05
CN1211191A (zh) 1999-03-17
PT859596E (pt) 2002-05-31
KR19990064041A (ko) 1999-07-26
ZA968398B (en) 1998-04-06
HUP9803002A3 (en) 2001-08-28
CA2234235A1 (fr) 1997-04-10
ES2167611T3 (es) 2002-05-16
NO981539L (no) 1998-06-02
DE69617723D1 (de) 2002-01-17
JPH11512740A (ja) 1999-11-02
EP0859596A2 (fr) 1998-08-26

Similar Documents

Publication Publication Date Title
DK0859596T3 (da) Vækstfaktorholdige gelformuleringer
EP0383363A3 (fr) Application d'agents pour la guérison de blessures
FI970747A (fi) Yhdistelmävalmiste käytettäväksi immunologisissa sairauksissa
DE68926051T2 (de) Polypeptid-polymer-konjugate mit wundheilender wirkung
EP1563844A3 (fr) Composition cicatrisante contenant la fibronectine du plasma humain
ATE135216T1 (de) Verwendung von spiperone-derivate zur immunosuppression
ES2176495T3 (es) Utilizacion de un antagonista de la bradiquinina, destinada a inducir y/o estimular el crecimiento de los cabellos y/o frenar su caida.
ES2065696T3 (es) Composicion farmaceutica.