DK0859596T3 - Vækstfaktorholdige gelformuleringer - Google Patents

Vækstfaktorholdige gelformuleringer

Info

Publication number
DK0859596T3
DK0859596T3 DK96935936T DK96935936T DK0859596T3 DK 0859596 T3 DK0859596 T3 DK 0859596T3 DK 96935936 T DK96935936 T DK 96935936T DK 96935936 T DK96935936 T DK 96935936T DK 0859596 T3 DK0859596 T3 DK 0859596T3
Authority
DK
Denmark
Prior art keywords
gel formulations
growth factor
gel
containing gel
topical
Prior art date
Application number
DK96935936T
Other languages
English (en)
Inventor
John Cini
Amy Finkenur
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Application granted granted Critical
Publication of DK0859596T3 publication Critical patent/DK0859596T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1808—Epidermal growth factor [EGF] urogastrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Colloid Chemistry (AREA)
  • Materials For Medical Uses (AREA)
DK96935936T 1995-10-06 1996-09-24 Vækstfaktorholdige gelformuleringer DK0859596T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/539,898 US5705485A (en) 1987-09-18 1995-10-06 Gel formulations containing growth factors
PCT/US1996/015288 WO1997012601A2 (en) 1995-10-06 1996-09-24 Gel formulations containing growth factors

Publications (1)

Publication Number Publication Date
DK0859596T3 true DK0859596T3 (da) 2002-03-04

Family

ID=24153118

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96935936T DK0859596T3 (da) 1995-10-06 1996-09-24 Vækstfaktorholdige gelformuleringer

Country Status (19)

Country Link
US (1) US5705485A (da)
EP (1) EP0859596B1 (da)
JP (1) JP4001382B2 (da)
KR (1) KR100444417B1 (da)
CN (1) CN1142791C (da)
AT (1) ATE209900T1 (da)
AU (1) AU706806B2 (da)
BR (1) BR9610790A (da)
CA (1) CA2234235C (da)
CZ (1) CZ294676B6 (da)
DE (1) DE69617723T2 (da)
DK (1) DK0859596T3 (da)
ES (1) ES2167611T3 (da)
HU (1) HU223880B1 (da)
NO (1) NO981539L (da)
PL (1) PL187174B1 (da)
PT (1) PT859596E (da)
WO (1) WO1997012601A2 (da)
ZA (1) ZA968398B (da)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE253374T1 (de) * 1998-03-07 2003-11-15 Dae Woong Pharma Topische zusammensetzung enthaltend menschlichen epidermalen wachstumsfaktor
US20030147860A1 (en) * 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
ES2288024T3 (es) 1998-09-04 2007-12-16 Scios Inc. Composiciones de hidrogel para la liberacion controlada en la administracion de factores de crecimiento.
US6057280A (en) 1998-11-19 2000-05-02 Huish Detergents, Inc. Compositions containing α-sulfofatty acid esters and methods of making and using the same
DE19925519A1 (de) 1999-06-04 2000-12-07 Lohmann Therapie Syst Lts Wundauflage zur gesteuerten Abgabe von Wirkstoff an Wunden und Verfahren zu ihrer Herstellung
AU5624400A (en) * 1999-06-18 2001-01-09 Collaborative Group, Ltd., The Hyaluronic acid film and matrix for sustained gene transfer
US8188043B2 (en) * 1999-07-28 2012-05-29 The Board Of Trustees Of The Leland Stanford Jr. University Nicotine in therapeutic angiogenesis and vasculogenesis
AU782519B2 (en) 1999-11-09 2005-08-04 Denki Kagaku Kogyo Kabushiki Kaisha Use of soluble cellulose derivative having been made hardly soluble in water and process for producing the same
DE10048260A1 (de) * 2000-09-29 2002-04-11 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Aminoguanidin und/oder dessen Derivaten und Strukturanaloga zur Hautaufhellung von Altersflecken und/oder zur Verhinderung der Hautbräunung, insbesondere der durch UV-Strahlung hervorgerufenen Hautbräunung
US6703039B2 (en) * 2000-12-06 2004-03-09 Bausch & Lomb Incorporated Reversible gelling system for ocular drug delivery
WO2002058718A2 (en) * 2001-01-26 2002-08-01 Genetix Pharmaceuticals, Inc. Use of compositions containing pdgf-bb for promoting angiogenesis
DE10140623A1 (de) * 2001-08-18 2003-03-06 Nawa Heilmittel Gmbh Pharmazeutisches Präparat zur Behandlung von Wunden
US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US7037504B2 (en) * 2001-10-23 2006-05-02 Waratah Pharmaceuticals, Inc. Epidermal growth factor protein and gene, and methods of use therefor
US20080086792A1 (en) 2006-10-13 2008-04-17 Thomas Charles Kuracina Method and apparatus for diverting sweat, liquid, moisture or the like from an eye
CA2476656C (en) 2002-02-21 2008-11-25 Encelle, Inc. Immobilized bioactive hydrogel matrices as surface coatings
US20030220632A1 (en) * 2002-05-23 2003-11-27 Wolfgang Strasser Method of using gel sheets for laser treatment
JP4516844B2 (ja) 2002-09-16 2010-08-04 エイジェニックス インコーポレイテッド 創傷の処置におけるラクトフェリン
ES2593113T3 (es) * 2003-08-07 2016-12-05 Allergan, Inc. Composiciones para el suministro de agentes terapéuticos en los ojos y métodos para obtener y usar los mismos
JP2007513693A (ja) 2003-12-11 2007-05-31 テイコク ファーマ ユーエスエー インコーポレーテッド 皮膚創傷の処置のための方法および組成物
CN100411615C (zh) * 2003-12-12 2008-08-20 上海第二医科大学附属瑞金医院 氨基胍对难愈创面的防治作用
WO2005077402A1 (en) * 2004-02-11 2005-08-25 Virchow Biotech Private Limited Honey based gel formulations
US20060036211A1 (en) * 2004-07-29 2006-02-16 X-Sten, Inc. Spinal ligament modification kit
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
EP1811933B1 (en) 2004-09-28 2016-03-23 Atrium Medical Corporation Barrier layer
KR20080017362A (ko) * 2005-06-17 2008-02-26 제넨테크, 인크. 창상 치유를 위한 ｖｅｇｆ의 용도
WO2007013100A1 (en) * 2005-07-26 2007-02-01 Virchow Biotech Private Limited Gel formulation comprising platelet derived growth factor
JP2009502365A (ja) * 2005-07-29 2009-01-29 ヴァートス メディカル インコーポレーテッド 経皮的組織切除装置および同方法
US20070055263A1 (en) * 2005-07-29 2007-03-08 X-Sten Corp. Tools for Percutaneous Spinal Ligament Decompression and Device for Supporting Same
FR2891149B1 (fr) 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
US9278161B2 (en) * 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
DE102005055275A1 (de) * 2005-11-17 2007-05-24 Ursapharm Arzneimittel Gmbh & Co. Kg Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung
KR100687281B1 (ko) * 2005-11-30 2007-02-27 한국과학기술연구원 생리 활성 물질이 결합된 조직 재생용 주입형 온도 감응성플루로닉 유도체 하이드로겔 및 이의 제조 방법
KR100742313B1 (ko) * 2006-03-21 2007-07-24 퓨리메드 주식회사 신규한 혈소판 유래 성장 인자(ｐｄｇｆ) ｂ 폴리펩타이드및 이의 유전자
US7942830B2 (en) 2006-05-09 2011-05-17 Vertos Medical, Inc. Ipsilateral approach to minimally invasive ligament decompression procedure
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
KR101437191B1 (ko) * 2006-10-26 2014-09-03 센주 세이야꾸 가부시키가이샤 안과용 수성 액제
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
EP2114268A4 (en) * 2007-02-12 2010-03-03 Vertos Medical Inc TISSUE EXTRACTION DEVICES AND METHODS
US20090118709A1 (en) * 2007-11-06 2009-05-07 Vertos Medical, Inc. A Delaware Corporation Tissue Excision Tool, Kits and Methods of Using the Same
JP5582711B2 (ja) * 2008-09-25 2014-09-03 株式会社エー・アイ・システムプロダクト ローション状の塗薬
USD611146S1 (en) 2008-10-23 2010-03-02 Vertos Medical, Inc. Tissue modification device
USD619253S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
USD621939S1 (en) 2008-10-23 2010-08-17 Vertos Medical, Inc. Tissue modification device
USD610259S1 (en) 2008-10-23 2010-02-16 Vertos Medical, Inc. Tissue modification device
USD619252S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
DK2480204T3 (da) * 2009-09-22 2014-02-03 Vlife Sciences Technologies Pvt Ltd Topikal formulering til diabetiske fodsår
EP2593141B1 (en) 2010-07-16 2018-07-04 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
EP2729219A4 (en) * 2011-07-06 2015-04-01 Orf Líftaekni Hf METHOD OF USING NON-VEGETABLE GROWTH FACTOR STABILIZED FOR SKIN CARE
JP2014532713A (ja) 2011-11-02 2014-12-08 ハルシオン，インコーポレイテッド 創傷処置の方法及び組成物
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US9422497B2 (en) 2012-09-21 2016-08-23 Exxonmobil Research And Engineering Company Synthetic lubricant basestocks and methods of preparation thereof
EP2970422B1 (en) 2013-03-15 2018-04-18 F.Hoffmann-La Roche Ag Il-22 polypeptides and il-22 fc fusion proteins and methods of use
EP2968462B1 (en) 2013-03-15 2020-12-23 The Jackson Laboratory Methods for promoting wound healing and hair growth
US9675537B2 (en) 2014-06-30 2017-06-13 Johnson & Johnson Consumer Inc. Hair growth composition and method
CA2962954A1 (en) * 2014-10-14 2016-04-21 Samuel Lynch Compositions for treating wounds
WO2017035280A1 (en) * 2015-08-24 2017-03-02 Nugene, Inc. Skin damage healing aids and dressings
US20190070299A1 (en) * 2016-02-23 2019-03-07 Matripharm International Inc. Dual-rate release formulation with high drug loading
EP4368128A3 (en) 2016-09-07 2024-07-17 Vertos Medical, Inc. Percutaneous lateral recess resection methods and instruments
US12558458B2 (en) 2017-05-18 2026-02-24 The Board Of Trustees Of The Leland Stanford Junior University Targeted in situ therapeutic delivery of secreted factors from stem cells for treatment of damaged tissue
JP7349995B2 (ja) 2018-01-26 2023-09-25 ジェネンテック， インコーポレイテッド ＩＬ－２２ Ｆｃ融合タンパク質及び使用方法
EP3743088B1 (en) 2018-01-26 2022-10-12 F. Hoffmann-La Roche AG Il-22 fc compositions and methods of use
KR20200123118A (ko) 2018-02-21 2020-10-28 제넨테크, 인크. IL-22 Fc 융합 단백질로 치료를 위한 투약
CN114601959A (zh) * 2020-11-23 2022-06-10 山东融元康医疗科技有限公司 一种医用皮肤护理敷料及其制备方法和应用
WO2023245144A1 (en) 2022-06-16 2023-12-21 Vertos Medical, Inc. Integrated instrument assembly

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190361B (it) * 1985-05-30 1988-02-16 Zambon Spa Composizione farmaceutica in crema per uso dermale ed oftalmico
US4717717A (en) * 1986-11-05 1988-01-05 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
NZ222413A (en) * 1986-11-05 1991-06-25 Ethicon Inc Compositions containing a polypeptide growth factor and a water-soluble cellulose polymer stabiliser
US5124316A (en) * 1986-11-14 1992-06-23 President And Fellows Of Harvard College Method for periodontal regeneration
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
KR0145278B1 (ko) * 1991-06-21 1998-07-15 브루스 엠. 에이센 골형성원 단백질 약제
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
AU3062392A (en) * 1991-11-04 1993-06-07 Novo Nordisk A/S Pdgf gel formulation
JP3102655B2 (ja) * 1991-12-27 2000-10-23 住友製薬株式会社 超音波制御による薬物放出製剤

Also Published As

Publication number Publication date
JP4001382B2 (ja) 2007-10-31
PL326064A1 (en) 1998-08-17
AU706806B2 (en) 1999-06-24
CN1142791C (zh) 2004-03-24
JPH11512740A (ja) 1999-11-02
US5705485A (en) 1998-01-06
PT859596E (pt) 2002-05-31
HU223880B1 (hu) 2005-02-28
DE69617723T2 (de) 2002-05-08
ES2167611T3 (es) 2002-05-16
DE69617723D1 (de) 2002-01-17
BR9610790A (pt) 1999-07-13
ZA968398B (en) 1998-04-06
CZ102498A3 (cs) 1999-08-11
CZ294676B6 (cs) 2005-02-16
EP0859596A2 (en) 1998-08-26
AU7370796A (en) 1997-04-28
PL187174B1 (pl) 2004-05-31
WO1997012601A3 (en) 1997-05-01
WO1997012601A2 (en) 1997-04-10
HUP9803002A2 (hu) 1999-04-28
CA2234235A1 (en) 1997-04-10
NO981539L (no) 1998-06-02
HUP9803002A3 (en) 2001-08-28
CA2234235C (en) 2002-05-14
EP0859596B1 (en) 2001-12-05
CN1211191A (zh) 1999-03-17
KR100444417B1 (ko) 2004-11-03
NO981539D0 (no) 1998-04-03
KR19990064041A (ko) 1999-07-26
ATE209900T1 (de) 2001-12-15

Similar Documents

Publication Publication Date Title
DK0859596T3 (da) Vækstfaktorholdige gelformuleringer
EP0383363A3 (en) Use of wound healing agents
DE68926051D1 (de) Polypeptid-polymer-konjugate mit wundheilender wirkung
EP1563844A3 (en) Wound healing formulations containing human plasma fibronectin
FI970747A0 (fi) Yhdistelmävalmiste käytettäväksi immunologisissa sairauksissa
DE69025943D1 (de) Verwendung von Spiperone-derivate zur Immunosuppression
FI886019A7 (fi) Laastari vaikuttavien aineiden valvotusti jakamiseksi iholle
PT941108E (pt) Cicatrizacao de feridas e tratamento da fibrose
ES2065696T3 (es) Composicion farmaceutica.
DK0951294T3 (da) Sårhelende formuleringer indeholdende humanplasmafibronectin