DE69617723T2 - Wachsumsfaktoren enthaltende gelformulierungen - Google Patents

Wachsumsfaktoren enthaltende gelformulierungen

Info

Publication number
DE69617723T2
DE69617723T2 DE69617723T DE69617723T DE69617723T2 DE 69617723 T2 DE69617723 T2 DE 69617723T2 DE 69617723 T DE69617723 T DE 69617723T DE 69617723 T DE69617723 T DE 69617723T DE 69617723 T2 DE69617723 T2 DE 69617723T2
Authority
DE
Germany
Prior art keywords
gel formulations
gel
growth factors
containing growth
formulas containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69617723T
Other languages
English (en)
Other versions
DE69617723D1 (de
Inventor
John Cini
Amy Finkenur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of DE69617723D1 publication Critical patent/DE69617723D1/de
Application granted granted Critical
Publication of DE69617723T2 publication Critical patent/DE69617723T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1808—Epidermal growth factor [EGF] urogastrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Colloid Chemistry (AREA)
DE69617723T 1995-10-06 1996-09-24 Wachsumsfaktoren enthaltende gelformulierungen Expired - Lifetime DE69617723T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/539,898 US5705485A (en) 1987-09-18 1995-10-06 Gel formulations containing growth factors
PCT/US1996/015288 WO1997012601A2 (en) 1995-10-06 1996-09-24 Gel formulations containing growth factors

Publications (2)

Publication Number Publication Date
DE69617723D1 DE69617723D1 (de) 2002-01-17
DE69617723T2 true DE69617723T2 (de) 2002-05-08

Family

ID=24153118

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69617723T Expired - Lifetime DE69617723T2 (de) 1995-10-06 1996-09-24 Wachsumsfaktoren enthaltende gelformulierungen

Country Status (19)

Country Link
US (1) US5705485A (de)
EP (1) EP0859596B1 (de)
JP (1) JP4001382B2 (de)
KR (1) KR100444417B1 (de)
CN (1) CN1142791C (de)
AT (1) ATE209900T1 (de)
AU (1) AU706806B2 (de)
BR (1) BR9610790A (de)
CA (1) CA2234235C (de)
CZ (1) CZ294676B6 (de)
DE (1) DE69617723T2 (de)
DK (1) DK0859596T3 (de)
ES (1) ES2167611T3 (de)
HU (1) HU223880B1 (de)
NO (1) NO981539L (de)
PL (1) PL187174B1 (de)
PT (1) PT859596E (de)
WO (1) WO1997012601A2 (de)
ZA (1) ZA968398B (de)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6491904B1 (en) * 1998-03-07 2002-12-10 Daewoong Pharmaceutical Co., Ltd. Topical composition containing human epidermal growth factor
US20030147860A1 (en) * 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
DE69936212T2 (de) 1998-09-04 2008-01-24 Scios Inc., Sunnyvale Hydrogelzusammensetzungen mit kontrollierter Freigabe für die Verabreichung von Wachstumsfaktoren
US6057280A (en) 1998-11-19 2000-05-02 Huish Detergents, Inc. Compositions containing α-sulfofatty acid esters and methods of making and using the same
DE19925519A1 (de) 1999-06-04 2000-12-07 Lohmann Therapie Syst Lts Wundauflage zur gesteuerten Abgabe von Wirkstoff an Wunden und Verfahren zu ihrer Herstellung
AU5624500A (en) * 1999-06-18 2001-01-09 Collaborative Group, Ltd., The Hyaluronic acid microspheres for sustained gene transfer
US8188043B2 (en) * 1999-07-28 2012-05-29 The Board Of Trustees Of The Leland Stanford Jr. University Nicotine in therapeutic angiogenesis and vasculogenesis
EP1228771A4 (de) 1999-11-09 2003-01-29 Denki Kagaku Kogyo Kk Verwendung löslicher cellulosederivate, die schwer löslich in wasser gemacht wurden und das verfahren zu ihrer herstellung
DE10048260A1 (de) * 2000-09-29 2002-04-11 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Aminoguanidin und/oder dessen Derivaten und Strukturanaloga zur Hautaufhellung von Altersflecken und/oder zur Verhinderung der Hautbräunung, insbesondere der durch UV-Strahlung hervorgerufenen Hautbräunung
US6703039B2 (en) * 2000-12-06 2004-03-09 Bausch & Lomb Incorporated Reversible gelling system for ocular drug delivery
WO2002058718A2 (en) * 2001-01-26 2002-08-01 Genetix Pharmaceuticals, Inc. Use of compositions containing pdgf-bb for promoting angiogenesis
DE10140623A1 (de) * 2001-08-18 2003-03-06 Nawa Heilmittel Gmbh Pharmazeutisches Präparat zur Behandlung von Wunden
US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US7037504B2 (en) * 2001-10-23 2006-05-02 Waratah Pharmaceuticals, Inc. Epidermal growth factor protein and gene, and methods of use therefor
DE60323943D1 (de) 2002-02-21 2008-11-20 Encelle Inc Immobilisierte bioaktive hydrogel matrizen für oberflächenbeschichtungen
US20080086792A1 (en) 2006-10-13 2008-04-17 Thomas Charles Kuracina Method and apparatus for diverting sweat, liquid, moisture or the like from an eye
US20030220632A1 (en) * 2002-05-23 2003-11-27 Wolfgang Strasser Method of using gel sheets for laser treatment
AU2003270690B2 (en) * 2002-09-16 2009-07-30 Agennix Incorporated Lactoferrin compositions and methods of wound treatment
AU2004263149B2 (en) * 2003-08-07 2010-08-19 Allergan, Inc. Compositions for delivery of therapeutics into the eyes and methods for making and using same
DE602004031303D1 (de) 2003-12-11 2011-03-17 Teikoku Pharma Usa Inc Verfahren und zusammensetzungen für die behandlung von hautwunden
CN100411615C (zh) * 2003-12-12 2008-08-20 上海第二医科大学附属瑞金医院 氨基胍对难愈创面的防治作用
WO2005077402A1 (en) * 2004-02-11 2005-08-25 Virchow Biotech Private Limited Honey based gel formulations
US7896879B2 (en) * 2004-07-29 2011-03-01 Vertos Medical, Inc. Spinal ligament modification
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
WO2006036969A2 (en) 2004-09-28 2006-04-06 Atrium Medical Corporation Formation of barrier layer
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
EP1904094A2 (de) * 2005-06-17 2008-04-02 Genentech, Inc. Verwendung von vegf zur wundheilung
WO2007013100A1 (en) * 2005-07-26 2007-02-01 Virchow Biotech Private Limited Gel formulation comprising platelet derived growth factor
US20070027464A1 (en) * 2005-07-29 2007-02-01 X-Sten, Corp. Device for resecting spinal tissue
WO2007016684A2 (en) * 2005-07-29 2007-02-08 X-Sten, Corp. Tools for percutaneous spinal ligament decompression and device for supporting same
FR2891149B1 (fr) * 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US9278161B2 (en) * 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
DE102005055275A1 (de) * 2005-11-17 2007-05-24 Ursapharm Arzneimittel Gmbh & Co. Kg Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung
KR100687281B1 (ko) * 2005-11-30 2007-02-27 한국과학기술연구원 생리 활성 물질이 결합된 조직 재생용 주입형 온도 감응성플루로닉 유도체 하이드로겔 및 이의 제조 방법
KR100742313B1 (ko) * 2006-03-21 2007-07-24 퓨리메드 주식회사 신규한 혈소판 유래 성장 인자(ｐｄｇｆ) ｂ 폴리펩타이드및 이의 유전자
US7942830B2 (en) 2006-05-09 2011-05-17 Vertos Medical, Inc. Ipsilateral approach to minimally invasive ligament decompression procedure
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
CN101528239B (zh) * 2006-10-26 2013-03-13 千寿制药株式会社 眼科用水性液体药剂
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
US20080221383A1 (en) * 2007-02-12 2008-09-11 Vertos Medical, Inc. Tissue excision devices and methods
US20090118709A1 (en) * 2007-11-06 2009-05-07 Vertos Medical, Inc. A Delaware Corporation Tissue Excision Tool, Kits and Methods of Using the Same
JP5582711B2 (ja) * 2008-09-25 2014-09-03 株式会社エー・アイ・システムプロダクト ローション状の塗薬
USD619252S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
USD610259S1 (en) 2008-10-23 2010-02-16 Vertos Medical, Inc. Tissue modification device
USD619253S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
USD621939S1 (en) 2008-10-23 2010-08-17 Vertos Medical, Inc. Tissue modification device
USD611146S1 (en) 2008-10-23 2010-03-02 Vertos Medical, Inc. Tissue modification device
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
US8741953B2 (en) * 2009-09-22 2014-06-03 Vlife Sciences Technologies Pvt. Ltd. Topical formulation for diabetic foot ulcers
US10322213B2 (en) 2010-07-16 2019-06-18 Atrium Medical Corporation Compositions and methods for altering the rate of hydrolysis of cured oil-based materials
WO2013005235A1 (en) * 2011-07-06 2013-01-10 Orf Liftaekni Hf Method of use of stabilised non-plant-derived growth factor in skin care
CN104080468A (zh) 2011-11-02 2014-10-01 哈尔西恩股份有限公司 用于创伤治疗的方法和组合物
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US9422497B2 (en) 2012-09-21 2016-08-23 Exxonmobil Research And Engineering Company Synthetic lubricant basestocks and methods of preparation thereof
WO2014152511A1 (en) 2013-03-15 2014-09-25 The Jackson Laboratory Methods for promoting wound healing and hair growth
JP6456356B2 (ja) 2013-03-15 2019-01-23 ジェネンテック， インコーポレイテッド ＩＬ−２２ポリペプチド及びＩＬ−２２Ｆｃ融合タンパク質並びに使用方法
US9675537B2 (en) 2014-06-30 2017-06-13 Johnson & Johnson Consumer Inc. Hair growth composition and method
MX2017004520A (es) 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
WO2017035280A1 (en) * 2015-08-24 2017-03-02 Nugene, Inc. Skin damage healing aids and dressings
CA3015400A1 (en) * 2016-02-23 2017-08-31 Matripharm International Inc. Dual-rate release formulation with high drug loading
EP3624731A4 (de) * 2017-05-18 2021-02-24 The Board of Trustees of the Leland Stanford Junior University Gezielte therapeutische in-situ-verabreichung von sekretierten faktoren aus stammzellen zur behandlung von beschädigtem gewebe
CA3087339A1 (en) 2018-01-26 2019-08-01 Genentech, Inc. Il-22 fc fusion proteins and methods of use
PT3743088T (pt) 2018-01-26 2022-12-05 Hoffmann La Roche Composições il-22 fc e métodos de utilização
WO2019165140A1 (en) 2018-02-21 2019-08-29 Genentech, Inc. DOSING FOR TREATMENT WITH IL-22 Fc FUSION PROTEINS
CN114601959A (zh) * 2020-11-23 2022-06-10 山东融元康医疗科技有限公司 一种医用皮肤护理敷料及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190361B (it) * 1985-05-30 1988-02-16 Zambon Spa Composizione farmaceutica in crema per uso dermale ed oftalmico
US4717717A (en) * 1986-11-05 1988-01-05 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
NZ235556A (en) * 1986-11-05 1991-06-25 Ethicon Inc Breast milk substitute containing recombinant human egf
US5124316A (en) * 1986-11-14 1992-06-23 President And Fellows Of Harvard College Method for periodontal regeneration
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
AU663328B2 (en) * 1991-06-21 1995-10-05 Genetics Institute, Llc Pharmaceutical formulations of osteogenic proteins
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
WO1993008825A1 (en) * 1991-11-04 1993-05-13 Zymogenetics, Inc. Pdgf gel formulation
JP3102655B2 (ja) * 1991-12-27 2000-10-23 住友製薬株式会社 超音波制御による薬物放出製剤

Also Published As

Publication number Publication date
WO1997012601A3 (en) 1997-05-01
JPH11512740A (ja) 1999-11-02
NO981539L (no) 1998-06-02
NO981539D0 (no) 1998-04-03
CN1211191A (zh) 1999-03-17
HUP9803002A2 (hu) 1999-04-28
HUP9803002A3 (en) 2001-08-28
JP4001382B2 (ja) 2007-10-31
PL187174B1 (pl) 2004-05-31
KR19990064041A (ko) 1999-07-26
CN1142791C (zh) 2004-03-24
KR100444417B1 (ko) 2004-11-03
AU7370796A (en) 1997-04-28
DE69617723D1 (de) 2002-01-17
US5705485A (en) 1998-01-06
HU223880B1 (hu) 2005-02-28
EP0859596A2 (de) 1998-08-26
CA2234235C (en) 2002-05-14
EP0859596B1 (de) 2001-12-05
PL326064A1 (en) 1998-08-17
ATE209900T1 (de) 2001-12-15
CZ102498A3 (cs) 1999-08-11
WO1997012601A2 (en) 1997-04-10
CZ294676B6 (cs) 2005-02-16
AU706806B2 (en) 1999-06-24
PT859596E (pt) 2002-05-31
ZA968398B (en) 1998-04-06
BR9610790A (pt) 1999-07-13
ES2167611T3 (es) 2002-05-16
CA2234235A1 (en) 1997-04-10
DK0859596T3 (da) 2002-03-04

Similar Documents

Publication Publication Date Title
DE69617723D1 (de) Wachsumsfaktoren enthaltende gelformulierungen
EP0383363A3 (de) Verwendung von Wundheilungsagentien
FI970747A (fi) Yhdistelmävalmiste käytettäväksi immunologisissa sairauksissa
DE68926051T2 (de) Polypeptid-polymer-konjugate mit wundheilender wirkung
EP1563844A3 (de) Formulierung für die Wundheilung mit menslichem Plasma Fibronektin
ES2063250T3 (es) Uso de la trombospondina para facilitar la curacion de las heridas.
ES2176495T3 (es) Utilizacion de un antagonista de la bradiquinina, destinada a inducir y/o estimular el crecimiento de los cabellos y/o frenar su caida.
ES2065696T3 (es) Composicion farmaceutica.
DK0951294T3 (da) Sårhelende formuleringer indeholdende humanplasmafibronectin
UA23369A (uk) Антисептичний перев`язний матеріал
BG96495A (en) Aplication of - interferon for the treatment of wounds in autommune vasculitis

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN