DK0684951T3 - Silylerede acetylcholinesterase-inhibitorer - Google Patents
Silylerede acetylcholinesterase-inhibitorerInfo
- Publication number
- DK0684951T3 DK0684951T3 DK94908615.1T DK94908615T DK0684951T3 DK 0684951 T3 DK0684951 T3 DK 0684951T3 DK 94908615 T DK94908615 T DK 94908615T DK 0684951 T3 DK0684951 T3 DK 0684951T3
- Authority
- DK
- Denmark
- Prior art keywords
- silylated
- acetylcholinesterase inhibitors
- compounds
- methods
- acetylcholinesterase
- Prior art date
Links
- 239000000544 cholinesterase inhibitor Substances 0.000 title abstract 2
- 206010012289 Dementia Diseases 0.000 abstract 1
- 150000001491 aromatic compounds Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93400385A EP0611769A1 (de) | 1993-02-16 | 1993-02-16 | Silytierte acetylcholinesterase Inhibitoren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0684951T3 true DK0684951T3 (da) | 1997-05-26 |
Family
ID=8214682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94908615.1T DK0684951T3 (da) | 1993-02-16 | 1994-01-25 | Silylerede acetylcholinesterase-inhibitorer |
Country Status (19)
| Country | Link |
|---|---|
| EP (2) | EP0611769A1 (de) |
| JP (1) | JP3516955B2 (de) |
| KR (1) | KR100336547B1 (de) |
| CN (1) | CN1043575C (de) |
| AT (1) | ATE152725T1 (de) |
| AU (1) | AU672885B2 (de) |
| CA (1) | CA2154870C (de) |
| DE (1) | DE69403068T2 (de) |
| DK (1) | DK0684951T3 (de) |
| ES (1) | ES2104358T3 (de) |
| FI (1) | FI111461B (de) |
| GR (1) | GR3024151T3 (de) |
| HU (1) | HUT72736A (de) |
| IL (1) | IL108623A0 (de) |
| MX (1) | MX9401175A (de) |
| NO (1) | NO305517B1 (de) |
| NZ (1) | NZ262247A (de) |
| WO (1) | WO1994019356A1 (de) |
| ZA (1) | ZA94925B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0627400A1 (de) * | 1993-06-04 | 1994-12-07 | Merrell Dow Pharmaceuticals Inc. | Aromatische Inhibitoren von Acetylcholinesterase |
| CN100431539C (zh) * | 2004-01-12 | 2008-11-12 | 和泓生物技术（上海）有限公司 | 乙酰胆碱酯酶抑制剂在制备治疗帕金森病药物中的应用 |
| JP5379692B2 (ja) | 2006-11-09 | 2013-12-25 | プロビオドルグ エージー | 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての３−ヒドロキシ−１，５−ジヒドロ−ピロール−２−オン誘導体 |
| US9126987B2 (en) | 2006-11-30 | 2015-09-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| CN101668525A (zh) | 2007-03-01 | 2010-03-10 | 前体生物药物股份公司 | 谷氨酰胺酰环化酶抑制剂的新用途 |
| US9656991B2 (en) | 2007-04-18 | 2017-05-23 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| AU2010294214B2 (en) | 2009-09-11 | 2015-05-07 | Vivoryon Therapeutics N.V. | Heterocylcic derivatives as inhibitors of glutaminyl cyclase |
| CN102905532A (zh) | 2010-02-09 | 2013-01-30 | 约翰斯.霍普金斯大学 | 用于改善认知功能的方法和组合物 |
| ES2586231T3 (es) | 2010-03-03 | 2016-10-13 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
| DK2545047T3 (da) | 2010-03-10 | 2014-07-28 | Probiodrug Ag | Heterocycliske inhibitorer af glutaminylcyclase (QC, EC 2.3.2.5) |
| WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| EP2686313B1 (de) | 2011-03-16 | 2016-02-03 | Probiodrug AG | Benzimidazolderivate als glutaminylcyclase-hemmer |
| EP3610890A1 (de) | 2012-11-14 | 2020-02-19 | The Johns Hopkins University | Verfahren und zusammensetzungen zur behandlung von schizophrenie |
| EP2968237A4 (de) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | Verfahren und zusammensetzungen zur verbesserung der kognitiven funktion |
| JP6433482B2 (ja) | 2013-03-15 | 2018-12-05 | エージンバイオ， インコーポレイテッド | 認知機能を改善するための方法および組成物 |
| US10159648B2 (en) | 2015-05-22 | 2018-12-25 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| PL3461819T3 (pl) | 2017-09-29 | 2020-11-30 | Probiodrug Ag | Inhibitory cyklazy glutaminylowej |
| CN112047973B (zh) * | 2019-06-06 | 2022-11-18 | 上海科技大学 | 一种大麻素类化合物，其制备方法、组合物和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0403713A1 (de) * | 1989-06-22 | 1990-12-27 | Merrell Dow Pharmaceuticals Inc. | Acetylcholinesterase-Inhibitoren |
-
1993
- 1993-02-16 EP EP93400385A patent/EP0611769A1/de not_active Withdrawn
-
1994
- 1994-01-25 CN CN94191196A patent/CN1043575C/zh not_active Expired - Fee Related
- 1994-01-25 ES ES94908615T patent/ES2104358T3/es not_active Expired - Lifetime
- 1994-01-25 DK DK94908615.1T patent/DK0684951T3/da active
- 1994-01-25 CA CA002154870A patent/CA2154870C/en not_active Expired - Fee Related
- 1994-01-25 NZ NZ262247A patent/NZ262247A/en unknown
- 1994-01-25 HU HU9502406A patent/HUT72736A/hu unknown
- 1994-01-25 WO PCT/US1994/000720 patent/WO1994019356A1/en active IP Right Grant
- 1994-01-25 EP EP94908615A patent/EP0684951B1/de not_active Expired - Lifetime
- 1994-01-25 KR KR1019950703485A patent/KR100336547B1/ko not_active IP Right Cessation
- 1994-01-25 JP JP51897494A patent/JP3516955B2/ja not_active Expired - Fee Related
- 1994-01-25 DE DE69403068T patent/DE69403068T2/de not_active Expired - Lifetime
- 1994-01-25 AT AT94908615T patent/ATE152725T1/de active
- 1994-01-25 AU AU61641/94A patent/AU672885B2/en not_active Ceased
- 1994-02-10 ZA ZA94925A patent/ZA94925B/xx unknown
- 1994-02-11 IL IL10862394A patent/IL108623A0/xx unknown
- 1994-02-15 MX MX9401175A patent/MX9401175A/es not_active Application Discontinuation
-
1995
- 1995-08-15 FI FI953851A patent/FI111461B/fi not_active IP Right Cessation
- 1995-08-15 NO NO953201A patent/NO305517B1/no unknown
-
1997
- 1997-07-16 GR GR970401801T patent/GR3024151T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO953201D0 (no) | 1995-08-15 |
| AU6164194A (en) | 1994-09-14 |
| ES2104358T3 (es) | 1997-10-01 |
| ZA94925B (en) | 1994-08-25 |
| KR960701068A (ko) | 1996-02-24 |
| WO1994019356A1 (en) | 1994-09-01 |
| FI953851A0 (fi) | 1995-08-15 |
| CN1043575C (zh) | 1999-06-09 |
| ATE152725T1 (de) | 1997-05-15 |
| DE69403068T2 (de) | 1997-12-11 |
| JP3516955B2 (ja) | 2004-04-05 |
| FI111461B (fi) | 2003-07-31 |
| NZ262247A (en) | 1996-01-26 |
| MX9401175A (es) | 1994-08-31 |
| EP0684951A1 (de) | 1995-12-06 |
| AU672885B2 (en) | 1996-10-17 |
| HUT72736A (en) | 1996-05-28 |
| FI953851A (fi) | 1995-08-15 |
| CN1117733A (zh) | 1996-02-28 |
| JPH08507059A (ja) | 1996-07-30 |
| IL108623A0 (en) | 1994-05-30 |
| EP0611769A1 (de) | 1994-08-24 |
| EP0684951B1 (de) | 1997-05-07 |
| CA2154870A1 (en) | 1994-09-01 |
| KR100336547B1 (ko) | 2002-11-02 |
| DE69403068D1 (en) | 1997-06-12 |
| NO305517B1 (no) | 1999-06-14 |
| GR3024151T3 (en) | 1997-10-31 |
| NO953201L (no) | 1995-08-15 |
| CA2154870C (en) | 1998-10-27 |
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