HUT71550A - Pharmaceutical agents containing quinuclidine, piperidine or azanorbornane derivatives for treatment of emesis - Google Patents
Pharmaceutical agents containing quinuclidine, piperidine or azanorbornane derivatives for treatment of emesisInfo
- Publication number
- HUT71550A HUT71550A HU9401676A HU9401676A HUT71550A HU T71550 A HUT71550 A HU T71550A HU 9401676 A HU9401676 A HU 9401676A HU 9401676 A HU9401676 A HU 9401676A HU T71550 A HUT71550 A HU T71550A
- Authority
- HU
- Hungary
- Prior art keywords
- piperidine
- emesis
- treatment
- pharmaceutical agents
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
The present invention relates to compounds useful for treating or preventing emesis in mammals, including humans, using certain quinuclidine derivatives, piperidine derivatives, azanorbornane derivatives and related compounds.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/072,629 US5393762A (en) | 1993-06-04 | 1993-06-04 | Pharmaceutical agents for treatment of emesis |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9401676D0 HU9401676D0 (en) | 1994-09-28 |
HUT71550A true HUT71550A (en) | 1995-12-28 |
HU222243B1 HU222243B1 (en) | 2003-05-28 |
Family
ID=22108825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9401676A HU222243B1 (en) | 1993-06-04 | 1994-06-03 | Process for the preparation of pharmaceutical compositions containing piperidine or azabicyclooctane derivatives for treatment of emesis |
Country Status (19)
Country | Link |
---|---|
US (1) | US5393762A (en) |
EP (1) | EP0627221B1 (en) |
JP (1) | JP2671972B2 (en) |
KR (1) | KR100190729B1 (en) |
CN (1) | CN1100535C (en) |
AT (1) | ATE209490T1 (en) |
AU (1) | AU666077B2 (en) |
CA (1) | CA2124990C (en) |
DE (1) | DE69429208T2 (en) |
DK (1) | DK0627221T3 (en) |
ES (1) | ES2164088T3 (en) |
HU (1) | HU222243B1 (en) |
IL (1) | IL109802A (en) |
MY (1) | MY115310A (en) |
NZ (1) | NZ260674A (en) |
PT (1) | PT627221E (en) |
RU (1) | RU2135179C1 (en) |
TW (1) | TW318791B (en) |
ZA (1) | ZA943896B (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0587723T3 (en) * | 1991-05-31 | 1996-04-01 | Pfizer | quinuclidine derivatives |
UA39168C2 (en) * | 1991-06-20 | 2001-06-15 | Пфайзер, Інк. | Fluoroalkoxyphenyl derivatives of pyperidine or quinuclidine AS antagonists of P substance and pharmaceutical composition based thereon |
EP0916346A3 (en) | 1991-09-20 | 2000-12-06 | Glaxo Group Limited | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis |
US6048859A (en) | 1992-06-29 | 2000-04-11 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
DE69318854T2 (en) * | 1993-03-04 | 1998-10-08 | Pfizer | SPIROAZACYCLIC DERIVATIVES AS SUBSTANCE P ANTAGONISTS |
GB9305718D0 (en) * | 1993-03-19 | 1993-05-05 | Glaxo Group Ltd | Medicaments |
US5576317A (en) * | 1994-12-09 | 1996-11-19 | Pfizer Inc. | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis |
WO1996030367A1 (en) * | 1995-03-27 | 1996-10-03 | Hisamitsu Pharmaceutical Co., Inc. | Piperidine derivatives |
TW340842B (en) * | 1995-08-24 | 1998-09-21 | Pfizer | Substituted benzylaminopiperidine compounds |
TW458774B (en) * | 1995-10-20 | 2001-10-11 | Pfizer | Antiemetic pharmaceutical compositions |
US6329396B1 (en) | 1996-06-10 | 2001-12-11 | Pfizer Inc. | Substituted benzylaminopiperidine compounds |
GB9708484D0 (en) | 1997-04-25 | 1997-06-18 | Merck Sharp & Dohme | Therapeutic agents |
CA2291734A1 (en) * | 1997-06-27 | 1999-01-07 | Merck Sharp & Dohme Limited | Substituted 3-(benzylamino)piperidine derivatives and their use as therapeutic agents |
EP1145714A4 (en) * | 1998-11-27 | 2004-12-15 | Takeda Chemical Industries Ltd | Drugs |
NZ501211A (en) * | 1999-01-29 | 2001-10-26 | Pfizer Prod Inc | Pharmaceutical composition comprising macrolide antibiotic like erythromycin and a Substance P antagonist, and method for treating cancer, bacterial and protozoal infection in non-humans |
US6255320B1 (en) * | 1999-06-01 | 2001-07-03 | Pfizer Inc. | Polymorphs of a crystalline azo-bicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions |
US6387925B1 (en) * | 1999-06-01 | 2002-05-14 | Pfizer Inc. | Polymorphs of a crystalline azo-bicyclo (2.2.2) oct-3-yl amine citrate and their pharmaceutical compositions |
US6262067B1 (en) * | 1999-06-22 | 2001-07-17 | Pfizer Inc. | Polymorphs of a crystalline azo-bicyclo 2,2,2 OCT-3-yl amine dihydrochloride and their pharmaceutical compositions |
IL142810A0 (en) * | 2000-05-03 | 2002-03-10 | Pfizer Prod Inc | Pharmaceutical uses for fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles |
HUP0401154A2 (en) * | 2001-07-20 | 2004-10-28 | Pfizer Products Inc. | Use of nk-1 receptor antagonists to modify unwanted behavior in dogs, cats and horses |
JP5021318B2 (en) * | 2004-01-30 | 2012-09-05 | ファイザー・プロダクツ・インク | Antibacterial preservatives for achieving multi-dose formulations using β-cyclodextrin in liquid dosage forms |
AU2005216706B2 (en) | 2004-01-30 | 2007-11-29 | Pfizer Products Inc. | NK-1 receptor antagonists anesthesia recovery |
SI1713801T1 (en) * | 2004-02-02 | 2008-04-30 | Pfizer Prod Inc | Process for preparation of 1-(2s,3s)-2-benzhydr yl-n-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine |
WO2014197137A1 (en) * | 2013-04-29 | 2014-12-11 | Howard Brooks-Korn | Diversion-resistant formulation |
US11040947B2 (en) | 2017-03-22 | 2021-06-22 | The Research Foundation For The State University Of New York | Substituted quinazolines as matrix metalloproteinase-9 hemopexin domain inhibitors |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8527052D0 (en) * | 1985-11-02 | 1985-12-04 | Beecham Group Plc | Compounds |
WO1990005525A1 (en) * | 1988-11-23 | 1990-05-31 | Pfizer Inc. | Quinuclidine derivatives as substance p antagonists |
US5232929A (en) * | 1990-11-28 | 1993-08-03 | Pfizer Inc. | 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use |
HUT62891A (en) * | 1990-06-01 | 1993-06-28 | Pfizer | Process for producing 3-amino-2-arylquinuclidine compounds and pharmaceuticql composition comprising such compounds |
CA2086434C (en) * | 1990-07-23 | 1998-09-22 | John A. Lowe, Iii | Quinuclidine derivatives |
HUT68667A (en) * | 1990-09-28 | 1995-07-28 | Pfizer | Fused ring analogs of nitrogen containing nonaromatic heterocycles |
AU652407B2 (en) * | 1991-01-10 | 1994-08-25 | Pfizer Inc. | N-alkyl quinuclidinium salts as substance P antagonists |
DE69200921T2 (en) * | 1991-03-01 | 1995-05-04 | Pfizer | 1-AZABICYCLO [3.2.2] NONAN-3-AMINE DERIVATIVES. |
BR9205807A (en) * | 1991-03-26 | 1994-06-28 | Pfizer | Stereo-selective preparation of substituted piperidines |
DE69232334T2 (en) * | 1991-05-22 | 2002-11-14 | Pfizer Inc., New York | SUBSTITUTED 3-AMINOCHINUCLIDINE |
DK0587723T3 (en) * | 1991-05-31 | 1996-04-01 | Pfizer | quinuclidine derivatives |
UA39168C2 (en) * | 1991-06-20 | 2001-06-15 | Пфайзер, Інк. | Fluoroalkoxyphenyl derivatives of pyperidine or quinuclidine AS antagonists of P substance and pharmaceutical composition based thereon |
TW202432B (en) * | 1991-06-21 | 1993-03-21 | Pfizer | |
EP0916346A3 (en) * | 1991-09-20 | 2000-12-06 | Glaxo Group Limited | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis |
BR9206500A (en) * | 1991-09-26 | 1995-10-03 | Pfizer | Heterocycles containing condensed tricyclic nitrogen as antagonists of the P receptor substance |
ATE161821T1 (en) * | 1991-11-12 | 1998-01-15 | Pfizer | AZYCLIC ETHYLENEDIAMINE DERIVATIVES AS 'SUBSTANCE P RECEPTOR' ANTAGONISTS |
JP2656702B2 (en) * | 1992-03-23 | 1997-09-24 | ファイザー製薬株式会社 | Peptide quinuclidine |
CA2134964C (en) * | 1992-05-18 | 1997-12-30 | Manoj C. Desai | Bridged aza-bicyclic derivatives as substance p antagonists |
DE69328975T2 (en) * | 1992-12-10 | 2000-11-09 | Pfizer Inc., New York | AMINOMETHYLENE SUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS ALSO SUBSTANCE P ANTAGONISTS |
DE69318854T2 (en) * | 1993-03-04 | 1998-10-08 | Pfizer | SPIROAZACYCLIC DERIVATIVES AS SUBSTANCE P ANTAGONISTS |
GB9305718D0 (en) * | 1993-03-19 | 1993-05-05 | Glaxo Group Ltd | Medicaments |
EP1105789A1 (en) * | 1998-08-14 | 2001-06-13 | ViA, Inc. | Mobile robotic snake |
-
1993
- 1993-06-04 US US08/072,629 patent/US5393762A/en not_active Expired - Lifetime
-
1994
- 1994-04-12 TW TW083103232A patent/TW318791B/zh active
- 1994-05-16 PT PT94303467T patent/PT627221E/en unknown
- 1994-05-16 ES ES94303467T patent/ES2164088T3/en not_active Expired - Lifetime
- 1994-05-16 DK DK94303467T patent/DK0627221T3/en active
- 1994-05-16 DE DE69429208T patent/DE69429208T2/en not_active Expired - Fee Related
- 1994-05-16 EP EP94303467A patent/EP0627221B1/en not_active Expired - Lifetime
- 1994-05-16 AT AT94303467T patent/ATE209490T1/en not_active IP Right Cessation
- 1994-05-26 IL IL10980294A patent/IL109802A/en not_active IP Right Cessation
- 1994-06-02 MY MYPI94001422A patent/MY115310A/en unknown
- 1994-06-02 JP JP6121042A patent/JP2671972B2/en not_active Expired - Fee Related
- 1994-06-02 CA CA002124990A patent/CA2124990C/en not_active Expired - Fee Related
- 1994-06-03 CN CN94106917A patent/CN1100535C/en not_active Expired - Fee Related
- 1994-06-03 KR KR1019940012527A patent/KR100190729B1/en not_active IP Right Cessation
- 1994-06-03 ZA ZA943896A patent/ZA943896B/en unknown
- 1994-06-03 NZ NZ260674A patent/NZ260674A/en not_active IP Right Cessation
- 1994-06-03 HU HU9401676A patent/HU222243B1/en not_active IP Right Cessation
- 1994-06-03 AU AU64521/94A patent/AU666077B2/en not_active Ceased
- 1994-06-03 RU RU94020410A patent/RU2135179C1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TW318791B (en) | 1997-11-01 |
ZA943896B (en) | 1995-12-04 |
HU222243B1 (en) | 2003-05-28 |
CN1121806A (en) | 1996-05-08 |
KR950000144A (en) | 1995-01-03 |
IL109802A0 (en) | 1994-08-26 |
JP2671972B2 (en) | 1997-11-05 |
EP0627221A2 (en) | 1994-12-07 |
EP0627221B1 (en) | 2001-11-28 |
NZ260674A (en) | 2000-07-28 |
US5393762A (en) | 1995-02-28 |
DK0627221T3 (en) | 2002-02-11 |
KR100190729B1 (en) | 1999-06-01 |
DE69429208D1 (en) | 2002-01-10 |
CA2124990C (en) | 1999-04-20 |
JPH0753362A (en) | 1995-02-28 |
HU9401676D0 (en) | 1994-09-28 |
AU666077B2 (en) | 1996-01-25 |
RU94020410A (en) | 1996-05-10 |
MY115310A (en) | 2003-05-31 |
ES2164088T3 (en) | 2002-02-16 |
AU6452194A (en) | 1994-12-15 |
CN1100535C (en) | 2003-02-05 |
IL109802A (en) | 2002-04-21 |
ATE209490T1 (en) | 2001-12-15 |
PT627221E (en) | 2002-04-29 |
EP0627221A3 (en) | 1995-08-02 |
RU2135179C1 (en) | 1999-08-27 |
DE69429208T2 (en) | 2002-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20030325 |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |