MX9401175A - Inhibidores de la acetilcolinesterasa sililada. - Google Patents
Inhibidores de la acetilcolinesterasa sililada.Info
- Publication number
- MX9401175A MX9401175A MX9401175A MX9401175A MX9401175A MX 9401175 A MX9401175 A MX 9401175A MX 9401175 A MX9401175 A MX 9401175A MX 9401175 A MX9401175 A MX 9401175A MX 9401175 A MX9401175 A MX 9401175A
- Authority
- MX
- Mexico
- Prior art keywords
- sililed
- acethylcholinesterase
- inhibitors
- compounds
- methods
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 206010012289 Dementia Diseases 0.000 abstract 1
- 150000001491 aromatic compounds Chemical class 0.000 abstract 1
- 239000000544 cholinesterase inhibitor Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
La presente invención se refiere a los compuestos aromáticos sililados fluorados que poseen actividad anticolinesterasa y los métodos de tratamiento para las Demencias Degenerativas usando estos compuestos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93400385A EP0611769A1 (en) | 1993-02-16 | 1993-02-16 | Silylated acetylcholinesterase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9401175A true MX9401175A (es) | 1994-08-31 |
Family
ID=8214682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9401175A MX9401175A (es) | 1993-02-16 | 1994-02-15 | Inhibidores de la acetilcolinesterasa sililada. |
Country Status (19)
| Country | Link |
|---|---|
| EP (2) | EP0611769A1 (es) |
| JP (1) | JP3516955B2 (es) |
| KR (1) | KR100336547B1 (es) |
| CN (1) | CN1043575C (es) |
| AT (1) | ATE152725T1 (es) |
| AU (1) | AU672885B2 (es) |
| CA (1) | CA2154870C (es) |
| DE (1) | DE69403068T2 (es) |
| DK (1) | DK0684951T3 (es) |
| ES (1) | ES2104358T3 (es) |
| FI (1) | FI111461B (es) |
| GR (1) | GR3024151T3 (es) |
| HU (1) | HUT72736A (es) |
| IL (1) | IL108623A0 (es) |
| MX (1) | MX9401175A (es) |
| NO (1) | NO305517B1 (es) |
| NZ (1) | NZ262247A (es) |
| WO (1) | WO1994019356A1 (es) |
| ZA (1) | ZA94925B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0627400A1 (en) * | 1993-06-04 | 1994-12-07 | Merrell Dow Pharmaceuticals Inc. | Aromatic acetylcholinesterase inhibitors |
| CN100431539C (zh) * | 2004-01-12 | 2008-11-12 | 和泓生物技术（上海）有限公司 | 乙酰胆碱酯酶抑制剂在制备治疗帕金森病药物中的应用 |
| US8278345B2 (en) | 2006-11-09 | 2012-10-02 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| WO2008065141A1 (en) | 2006-11-30 | 2008-06-05 | Probiodrug Ag | Novel inhibitors of glutaminyl cyclase |
| KR20090115951A (ko) | 2007-03-01 | 2009-11-10 | 프로비오드룩 아게 | 글루타미닐 사이클라제 저해제의 신규 용도 |
| US9656991B2 (en) | 2007-04-18 | 2017-05-23 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| JP5934645B2 (ja) | 2009-09-11 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体 |
| BR112012019923A2 (pt) | 2010-02-09 | 2016-08-09 | Univ Johns Hopkins | métodos e composições para melhorar a função cognitiva |
| JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
| EP2545047B9 (en) | 2010-03-10 | 2015-06-10 | Probiodrug AG | Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5) |
| EP2560953B1 (en) | 2010-04-21 | 2016-01-06 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
| US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
| WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| DK2968220T3 (da) | 2013-03-15 | 2021-06-14 | Agenebio Inc | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
| CA2986598C (en) | 2015-05-22 | 2023-09-26 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| DK3461819T3 (da) | 2017-09-29 | 2020-08-10 | Probiodrug Ag | Inhibitorer af glutaminylcyklase |
| CN112047973B (zh) * | 2019-06-06 | 2022-11-18 | 上海科技大学 | 一种大麻素类化合物，其制备方法、组合物和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0403713A1 (en) * | 1989-06-22 | 1990-12-27 | Merrell Dow Pharmaceuticals Inc. | Novel acetylcholinesterase inhibitors |
-
1993
- 1993-02-16 EP EP93400385A patent/EP0611769A1/en not_active Withdrawn
-
1994
- 1994-01-25 JP JP51897494A patent/JP3516955B2/ja not_active Expired - Fee Related
- 1994-01-25 NZ NZ262247A patent/NZ262247A/en unknown
- 1994-01-25 KR KR1019950703485A patent/KR100336547B1/ko not_active IP Right Cessation
- 1994-01-25 AT AT94908615T patent/ATE152725T1/de active
- 1994-01-25 CA CA002154870A patent/CA2154870C/en not_active Expired - Fee Related
- 1994-01-25 CN CN94191196A patent/CN1043575C/zh not_active Expired - Fee Related
- 1994-01-25 DE DE69403068T patent/DE69403068T2/de not_active Expired - Lifetime
- 1994-01-25 ES ES94908615T patent/ES2104358T3/es not_active Expired - Lifetime
- 1994-01-25 AU AU61641/94A patent/AU672885B2/en not_active Ceased
- 1994-01-25 EP EP94908615A patent/EP0684951B1/en not_active Expired - Lifetime
- 1994-01-25 DK DK94908615.1T patent/DK0684951T3/da active
- 1994-01-25 HU HU9502406A patent/HUT72736A/hu unknown
- 1994-01-25 WO PCT/US1994/000720 patent/WO1994019356A1/en active IP Right Grant
- 1994-02-10 ZA ZA94925A patent/ZA94925B/xx unknown
- 1994-02-11 IL IL10862394A patent/IL108623A0/xx unknown
- 1994-02-15 MX MX9401175A patent/MX9401175A/es not_active Application Discontinuation
-
1995
- 1995-08-15 NO NO953201A patent/NO305517B1/no unknown
- 1995-08-15 FI FI953851A patent/FI111461B/fi not_active IP Right Cessation
-
1997
- 1997-07-16 GR GR970401801T patent/GR3024151T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0684951B1 (en) | 1997-05-07 |
| DE69403068D1 (en) | 1997-06-12 |
| KR960701068A (ko) | 1996-02-24 |
| WO1994019356A1 (en) | 1994-09-01 |
| EP0684951A1 (en) | 1995-12-06 |
| NO953201D0 (no) | 1995-08-15 |
| FI953851A (fi) | 1995-08-15 |
| FI111461B (fi) | 2003-07-31 |
| NZ262247A (en) | 1996-01-26 |
| JP3516955B2 (ja) | 2004-04-05 |
| CN1117733A (zh) | 1996-02-28 |
| IL108623A0 (en) | 1994-05-30 |
| HUT72736A (en) | 1996-05-28 |
| FI953851A0 (fi) | 1995-08-15 |
| CA2154870C (en) | 1998-10-27 |
| NO953201L (no) | 1995-08-15 |
| CA2154870A1 (en) | 1994-09-01 |
| GR3024151T3 (en) | 1997-10-31 |
| JPH08507059A (ja) | 1996-07-30 |
| EP0611769A1 (en) | 1994-08-24 |
| AU6164194A (en) | 1994-09-14 |
| DE69403068T2 (de) | 1997-12-11 |
| KR100336547B1 (ko) | 2002-11-02 |
| AU672885B2 (en) | 1996-10-17 |
| CN1043575C (zh) | 1999-06-09 |
| ES2104358T3 (es) | 1997-10-01 |
| ZA94925B (en) | 1994-08-25 |
| DK0684951T3 (da) | 1997-05-26 |
| ATE152725T1 (de) | 1997-05-15 |
| NO305517B1 (no) | 1999-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |