ZA94925B - Silylated acetylcholinesterase inhibitors - Google Patents
Silylated acetylcholinesterase inhibitorsInfo
- Publication number
- ZA94925B ZA94925B ZA94925A ZA94925A ZA94925B ZA 94925 B ZA94925 B ZA 94925B ZA 94925 A ZA94925 A ZA 94925A ZA 94925 A ZA94925 A ZA 94925A ZA 94925 B ZA94925 B ZA 94925B
- Authority
- ZA
- South Africa
- Prior art keywords
- silylated
- acetylcholinesterase inhibitors
- compounds
- methods
- acetylcholinesterase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93400385A EP0611769A1 (en) | 1993-02-16 | 1993-02-16 | Silylated acetylcholinesterase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA94925B true ZA94925B (en) | 1994-08-25 |
Family
ID=8214682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA94925A ZA94925B (en) | 1993-02-16 | 1994-02-10 | Silylated acetylcholinesterase inhibitors |
Country Status (19)
| Country | Link |
|---|---|
| EP (2) | EP0611769A1 (xx) |
| JP (1) | JP3516955B2 (xx) |
| KR (1) | KR100336547B1 (xx) |
| CN (1) | CN1043575C (xx) |
| AT (1) | ATE152725T1 (xx) |
| AU (1) | AU672885B2 (xx) |
| CA (1) | CA2154870C (xx) |
| DE (1) | DE69403068T2 (xx) |
| DK (1) | DK0684951T3 (xx) |
| ES (1) | ES2104358T3 (xx) |
| FI (1) | FI111461B (xx) |
| GR (1) | GR3024151T3 (xx) |
| HU (1) | HUT72736A (xx) |
| IL (1) | IL108623A0 (xx) |
| MX (1) | MX9401175A (xx) |
| NO (1) | NO305517B1 (xx) |
| NZ (1) | NZ262247A (xx) |
| WO (1) | WO1994019356A1 (xx) |
| ZA (1) | ZA94925B (xx) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0627400A1 (en) * | 1993-06-04 | 1994-12-07 | Merrell Dow Pharmaceuticals Inc. | Aromatic acetylcholinesterase inhibitors |
| CN100431539C (zh) * | 2004-01-12 | 2008-11-12 | 和泓生物技术（上海）有限公司 | 乙酰胆碱酯酶抑制剂在制备治疗帕金森病药物中的应用 |
| WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
| WO2008065141A1 (en) | 2006-11-30 | 2008-06-05 | Probiodrug Ag | Novel inhibitors of glutaminyl cyclase |
| ZA200905537B (en) | 2007-03-01 | 2010-10-27 | Probiodrug Ag | New use of glutaminyl cyclase inhibitors |
| JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
| MX2012002993A (es) | 2009-09-11 | 2012-04-19 | Probiodrug Ag | Derivados heterociclicos como inhibidores de ciclasa glutaminilo. |
| CA2789014C (en) | 2010-02-09 | 2019-01-15 | Michela Gallagher | Methods and compositions for improving cognitive function |
| JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
| MX2012010470A (es) | 2010-03-10 | 2012-10-09 | Probiodrug Ag | Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5). |
| US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
| WO2012123563A1 (en) | 2011-03-16 | 2012-09-20 | Probiodrug Ag | Benz imidazole derivatives as inhibitors of glutaminyl cyclase |
| JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
| CA2904767C (en) | 2013-03-15 | 2022-06-21 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| EP3461819B1 (en) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
| CN112047973B (zh) * | 2019-06-06 | 2022-11-18 | 上海科技大学 | 一种大麻素类化合物，其制备方法、组合物和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0403713A1 (en) * | 1989-06-22 | 1990-12-27 | Merrell Dow Pharmaceuticals Inc. | Novel acetylcholinesterase inhibitors |
-
1993
- 1993-02-16 EP EP93400385A patent/EP0611769A1/en not_active Withdrawn
-
1994
- 1994-01-25 AT AT94908615T patent/ATE152725T1/de active
- 1994-01-25 NZ NZ262247A patent/NZ262247A/en unknown
- 1994-01-25 EP EP94908615A patent/EP0684951B1/en not_active Expired - Lifetime
- 1994-01-25 CN CN94191196A patent/CN1043575C/zh not_active Expired - Fee Related
- 1994-01-25 AU AU61641/94A patent/AU672885B2/en not_active Ceased
- 1994-01-25 DK DK94908615.1T patent/DK0684951T3/da active
- 1994-01-25 HU HU9502406A patent/HUT72736A/hu unknown
- 1994-01-25 KR KR1019950703485A patent/KR100336547B1/ko not_active IP Right Cessation
- 1994-01-25 CA CA002154870A patent/CA2154870C/en not_active Expired - Fee Related
- 1994-01-25 JP JP51897494A patent/JP3516955B2/ja not_active Expired - Fee Related
- 1994-01-25 DE DE69403068T patent/DE69403068T2/de not_active Expired - Lifetime
- 1994-01-25 ES ES94908615T patent/ES2104358T3/es not_active Expired - Lifetime
- 1994-01-25 WO PCT/US1994/000720 patent/WO1994019356A1/en active IP Right Grant
- 1994-02-10 ZA ZA94925A patent/ZA94925B/xx unknown
- 1994-02-11 IL IL10862394A patent/IL108623A0/xx unknown
- 1994-02-15 MX MX9401175A patent/MX9401175A/es not_active Application Discontinuation
-
1995
- 1995-08-15 FI FI953851A patent/FI111461B/fi not_active IP Right Cessation
- 1995-08-15 NO NO953201A patent/NO305517B1/no unknown
-
1997
- 1997-07-16 GR GR970401801T patent/GR3024151T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6164194A (en) | 1994-09-14 |
| MX9401175A (es) | 1994-08-31 |
| CN1117733A (zh) | 1996-02-28 |
| ATE152725T1 (de) | 1997-05-15 |
| IL108623A0 (en) | 1994-05-30 |
| NO953201D0 (no) | 1995-08-15 |
| CA2154870C (en) | 1998-10-27 |
| CA2154870A1 (en) | 1994-09-01 |
| HUT72736A (en) | 1996-05-28 |
| EP0684951B1 (en) | 1997-05-07 |
| NO953201L (no) | 1995-08-15 |
| ES2104358T3 (es) | 1997-10-01 |
| EP0611769A1 (en) | 1994-08-24 |
| WO1994019356A1 (en) | 1994-09-01 |
| JPH08507059A (ja) | 1996-07-30 |
| NZ262247A (en) | 1996-01-26 |
| GR3024151T3 (en) | 1997-10-31 |
| JP3516955B2 (ja) | 2004-04-05 |
| NO305517B1 (no) | 1999-06-14 |
| DK0684951T3 (da) | 1997-05-26 |
| DE69403068D1 (en) | 1997-06-12 |
| KR100336547B1 (ko) | 2002-11-02 |
| KR960701068A (ko) | 1996-02-24 |
| FI953851A0 (fi) | 1995-08-15 |
| AU672885B2 (en) | 1996-10-17 |
| FI953851A (fi) | 1995-08-15 |
| FI111461B (fi) | 2003-07-31 |
| DE69403068T2 (de) | 1997-12-11 |
| EP0684951A1 (en) | 1995-12-06 |
| CN1043575C (zh) | 1999-06-09 |
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