DK0630365T3 - Fremgangsmåde til fremstilling af beta-phenylisoserin og analoge deraf - Google Patents

Fremgangsmåde til fremstilling af beta-phenylisoserin og analoge deraf

Info

Publication number
DK0630365T3
DK0630365T3 DK93918746.4T DK93918746T DK0630365T3 DK 0630365 T3 DK0630365 T3 DK 0630365T3 DK 93918746 T DK93918746 T DK 93918746T DK 0630365 T3 DK0630365 T3 DK 0630365T3
Authority
DK
Denmark
Prior art keywords
pct
general formula
phenylisoserine
beta
date sep
Prior art date
Application number
DK93918746.4T
Other languages
Danish (da)
English (en)
Inventor
Alain Commercon
Jean-Dominique Bourzat
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0630365T3 publication Critical patent/DK0630365T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK93918746.4T 1992-03-10 1993-03-08 Fremgangsmåde til fremstilling af beta-phenylisoserin og analoge deraf DK0630365T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9202821A FR2688499B1 (fr) 1992-03-10 1992-03-10 Procede de preparation de la beta-phenylisoserine et de ses analogues.

Publications (1)

Publication Number Publication Date
DK0630365T3 true DK0630365T3 (da) 1998-03-02

Family

ID=9427518

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93918746.4T DK0630365T3 (da) 1992-03-10 1993-03-08 Fremgangsmåde til fremstilling af beta-phenylisoserin og analoge deraf

Country Status (25)

Country Link
US (2) US5608102A (enExample)
EP (1) EP0630365B1 (enExample)
JP (1) JP3278768B2 (enExample)
KR (1) KR100272650B1 (enExample)
AT (1) ATE159512T1 (enExample)
AU (1) AU667886B2 (enExample)
CA (1) CA2130333C (enExample)
CZ (1) CZ283613B6 (enExample)
DE (1) DE69314779T2 (enExample)
DK (1) DK0630365T3 (enExample)
ES (1) ES2109509T3 (enExample)
FI (1) FI113640B (enExample)
FR (1) FR2688499B1 (enExample)
GE (1) GEP19981430B (enExample)
GR (1) GR3025117T3 (enExample)
HU (1) HU213621B (enExample)
MX (1) MX9301268A (enExample)
NO (1) NO304515B1 (enExample)
NZ (1) NZ249899A (enExample)
PL (1) PL171551B1 (enExample)
RU (1) RU2103258C1 (enExample)
SK (1) SK281297B6 (enExample)
TW (1) TW252971B (enExample)
WO (1) WO1993017997A1 (enExample)
ZA (1) ZA931677B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO116549B1 (ro) * 1994-07-26 2001-03-30 Indena Spa Derivati de taxan, procedeu pentru prepararea acestora, intermediar pentru prepararea acestora si compozitie farmaceutica care ii contine
US6765015B2 (en) * 1995-12-13 2004-07-20 Xechem International, Inc. Halogenated paclitaxel derivatives
KR100225535B1 (ko) 1996-08-27 1999-10-15 정지석 파클리탁셀의 제조방법
NZ503206A (en) 1997-08-21 2002-05-31 Univ Florida State Method of taxane synthesis by treating with a base (potassium hydride or potassium hexamethyldisilazide) and a silylating agent (trialkylsilyl halide)
WO1999025334A1 (en) * 1997-11-19 1999-05-27 Xechem International, Inc. Halogenated paclitaxel derivatives
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
JP4776843B2 (ja) 1999-10-01 2011-09-21 イムノゲン インコーポレーティッド 免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法
JP2002080435A (ja) * 2000-06-26 2002-03-19 Kanegafuchi Chem Ind Co Ltd ３−アミノ−２−ヒドロキシプロピオン酸誘導体の製造法
KR100851515B1 (ko) 2001-03-07 2008-08-11 다이이찌 세이야꾸 가부시기가이샤 2-아제티디논 유도체의 제조방법
DE602007003312D1 (de) * 2007-02-22 2009-12-31 Indena Spa Verfahren zur Herstellung von (2r,3s)-3-Phenylisoserin-Methylester-Acetatsalz
DK2080764T3 (da) 2008-01-18 2012-09-24 Indena Spa Faste former af ortataxel
CN102408356A (zh) * 2011-09-28 2012-04-11 北京东方协和医药生物技术有限公司 一种多西他赛手性侧链中间体的制备方法
ES2896882T3 (es) * 2014-02-03 2022-02-28 Quadriga Biosciences Inc Beta-aminoácidos beta sustituidos y análogos como agentes quimioterapéuticos
CN111100026A (zh) * 2019-12-30 2020-05-05 重庆市碚圣医药科技股份有限公司 一种紫杉醇恶唑环侧链中间体的制备方法
CN112574134A (zh) * 2020-12-30 2021-03-30 重庆市碚圣医药科技股份有限公司 一种多西紫杉醇侧链的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5304670A (en) * 1989-08-23 1994-04-19 Centre National De La Recherche Scientifique Process for the enantioselective preparation of phenylisoserine derivatives
FR2658510B1 (fr) * 1990-02-21 1992-04-30 Rhone Poulenc Sante Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
US5294737A (en) * 1992-02-27 1994-03-15 The Research Foundation State University Of New York Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom

Also Published As

Publication number Publication date
DE69314779D1 (de) 1997-11-27
GR3025117T3 (en) 1998-01-30
FI944169A0 (fi) 1994-09-09
NO943280L (no) 1994-09-05
US5608102A (en) 1997-03-04
NO304515B1 (no) 1999-01-04
GEP19981430B (en) 1998-10-30
FI113640B (fi) 2004-05-31
FI944169L (fi) 1994-09-09
ATE159512T1 (de) 1997-11-15
HUT68540A (en) 1995-06-28
AU667886B2 (en) 1996-04-18
NO943280D0 (no) 1994-09-05
KR950700234A (ko) 1995-01-16
PL171551B1 (pl) 1997-05-30
FR2688499B1 (fr) 1994-05-06
EP0630365A1 (fr) 1994-12-28
CA2130333C (fr) 2002-11-26
HU9402590D0 (en) 1994-11-28
TW252971B (enExample) 1995-08-01
EP0630365B1 (fr) 1997-10-22
CZ218594A3 (en) 1995-11-15
AU3755793A (en) 1993-10-05
JPH07504425A (ja) 1995-05-18
SK108594A3 (en) 1995-02-08
JP3278768B2 (ja) 2002-04-30
FR2688499A1 (fr) 1993-09-17
KR100272650B1 (ko) 2000-11-15
NZ249899A (en) 1996-01-26
RU94045799A (ru) 1996-07-20
DE69314779T2 (de) 1998-02-26
HU213621B (en) 1997-08-28
WO1993017997A1 (fr) 1993-09-16
CA2130333A1 (fr) 1993-09-16
CZ283613B6 (cs) 1998-05-13
MX9301268A (es) 1993-09-01
ZA931677B (en) 1993-10-06
SK281297B6 (sk) 2001-02-12
ES2109509T3 (es) 1998-01-16
US5763628A (en) 1998-06-09
RU2103258C1 (ru) 1998-01-27

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