DK0586838T3 - Fremgangsmåde til fremstilling af et mikrosfærepræparat med forsinket frigivelse - Google Patents

Fremgangsmåde til fremstilling af et mikrosfærepræparat med forsinket frigivelse

Info

Publication number
DK0586838T3
DK0586838T3 DK93111455T DK93111455T DK0586838T3 DK 0586838 T3 DK0586838 T3 DK 0586838T3 DK 93111455 T DK93111455 T DK 93111455T DK 93111455 T DK93111455 T DK 93111455T DK 0586838 T3 DK0586838 T3 DK 0586838T3
Authority
DK
Denmark
Prior art keywords
water
microsphere preparation
release microsphere
give
active ingredient
Prior art date
Application number
DK93111455T
Other languages
English (en)
Inventor
Masao Kobayashi
Yukiko Nishioka
Takehiko Suzuki
Yasuhisa Matsukawa
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Application granted granted Critical
Publication of DK0586838T3 publication Critical patent/DK0586838T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93111455T 1992-07-16 1993-07-16 Fremgangsmåde til fremstilling af et mikrosfærepræparat med forsinket frigivelse DK0586838T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4189181A JP2651320B2 (ja) 1992-07-16 1992-07-16 徐放性マイクロスフェア製剤の製造方法

Publications (1)

Publication Number Publication Date
DK0586838T3 true DK0586838T3 (da) 1998-07-27

Family

ID=16236857

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93111455T DK0586838T3 (da) 1992-07-16 1993-07-16 Fremgangsmåde til fremstilling af et mikrosfærepræparat med forsinket frigivelse

Country Status (11)

Country Link
US (1) US5556642A (da)
EP (1) EP0586838B1 (da)
JP (1) JP2651320B2 (da)
KR (1) KR100211435B1 (da)
AT (1) ATE159854T1 (da)
CA (1) CA2099941C (da)
DE (1) DE69315026T2 (da)
DK (1) DK0586838T3 (da)
ES (1) ES2110544T3 (da)
GR (1) GR3025297T3 (da)
TW (1) TW227988B (da)

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Also Published As

Publication number Publication date
US5556642A (en) 1996-09-17
DE69315026T2 (de) 1998-03-26
EP0586838A1 (en) 1994-03-16
TW227988B (da) 1994-08-11
ATE159854T1 (de) 1997-11-15
KR100211435B1 (ko) 1999-08-02
KR940001882A (ko) 1994-02-16
CA2099941A1 (en) 1994-01-17
ES2110544T3 (es) 1998-02-16
JPH0632732A (ja) 1994-02-08
CA2099941C (en) 1999-12-28
JP2651320B2 (ja) 1997-09-10
EP0586838B1 (en) 1997-11-05
GR3025297T3 (en) 1998-02-27
DE69315026D1 (de) 1997-12-11

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