DK0585398T3 - HCV genomiske sekvenser til diagnostiske og terapeutiske midler - Google Patents

HCV genomiske sekvenser til diagnostiske og terapeutiske midler

Info

Publication number
DK0585398T3
DK0585398T3 DK92913881T DK92913881T DK0585398T3 DK 0585398 T3 DK0585398 T3 DK 0585398T3 DK 92913881 T DK92913881 T DK 92913881T DK 92913881 T DK92913881 T DK 92913881T DK 0585398 T3 DK0585398 T3 DK 0585398T3
Authority
DK
Denmark
Prior art keywords
hcv
diagnostic
therapeutic agents
genomic sequences
nucleotide sequence
Prior art date
Application number
DK92913881T
Other languages
Danish (da)
English (en)
Inventor
Tai-An Cha
Eileen Beall
Bruce Irvine
Janice Kolberg
Michael S Urdea
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24800701&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0585398(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of DK0585398T3 publication Critical patent/DK0585398T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DK92913881T 1991-05-08 1992-05-08 HCV genomiske sekvenser til diagnostiske og terapeutiske midler DK0585398T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69732691A 1991-05-08 1991-05-08
PCT/US1992/004036 WO1992019743A2 (en) 1991-05-08 1992-05-08 Hcv genomic sequences for diagnostics and therapeutics

Publications (1)

Publication Number Publication Date
DK0585398T3 true DK0585398T3 (da) 2004-02-02

Family

ID=24800701

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92913881T DK0585398T3 (da) 1991-05-08 1992-05-08 HCV genomiske sekvenser til diagnostiske og terapeutiske midler

Country Status (20)

Country Link
EP (2) EP1394256A3 (enExample)
JP (7) JPH06508026A (enExample)
KR (1) KR100193801B1 (enExample)
AT (1) ATE252154T1 (enExample)
BG (3) BG64627B1 (enExample)
CA (1) CA2108466C (enExample)
CZ (2) CZ288722B6 (enExample)
DE (1) DE69233234T2 (enExample)
DK (1) DK0585398T3 (enExample)
ES (1) ES2207633T3 (enExample)
FI (1) FI115725B (enExample)
HU (1) HU227548B1 (enExample)
IE (1) IE921482A1 (enExample)
NO (1) NO309532B1 (enExample)
PL (2) PL169880B1 (enExample)
PT (1) PT100472B (enExample)
RO (1) RO117267B1 (enExample)
RU (1) RU2155228C2 (enExample)
SK (1) SK284205B6 (enExample)
WO (1) WO1992019743A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0532167A3 (en) * 1991-08-09 1993-03-31 Immuno Japan Inc. Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
US5428145A (en) * 1991-08-09 1995-06-27 Immuno Japan, Inc. Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
EP0532258A2 (en) * 1991-09-09 1993-03-17 Immuno Japan Inc. Oligonucleotides and determination system of HCV genotypes
ATE231557T1 (de) * 1991-11-21 2003-02-15 Common Services Agency Detektion des hepatis-c virus.
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
EP0642592A4 (en) * 1992-05-29 1997-01-02 Abbott Lab LIGASE CHAIN REACTION STARTING WITH RNA SEQUENCES.
US6423489B1 (en) * 1992-09-10 2002-07-23 Isis Pharmaceuticals, Inc. Compositions and methods for treatment of Hepatitis C virus-associated diseases
ATE202383T1 (de) * 1992-09-10 2001-07-15 Isis Pharmaceuticals Inc Zusammensetzungen und verfahren für die behandlung von mit hepatitis c viren assoziierten krankheiten
JPH06153961A (ja) * 1992-11-27 1994-06-03 Imuno Japan:Kk C型肝炎ウイルス部分遺伝子、ならびにc型肝炎ウイルス遺 伝子の高感度検出法
US7258977B1 (en) 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
DE69334357D1 (de) 1992-11-27 2011-06-09 Innogenetics Nv Nachweis und Typisierung das Hepatitis C Virus (HCV) mittels 5'UTR und NS5 Nukleinsäuresequenzen
US7255997B1 (en) 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
US6762024B2 (en) 1993-04-27 2004-07-13 Innogenetics, S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
JPH0775585A (ja) * 1993-06-14 1995-03-20 Immuno Japan:Kk C型肝炎ウイルス関連オリゴヌクレオチドならびにc型肝炎 ウイルス遺伝子型判定方法
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
WO1995011918A1 (en) * 1993-10-29 1995-05-04 Srl, Inc. Antigen peptide compound and immunoassay method
JPH10503364A (ja) * 1994-05-10 1998-03-31 ザ ジェネラル ホスピタル コーポレーション C型肝炎ウイルスのアンチセンス阻害
DE69526973T3 (de) 1994-10-21 2010-01-07 Innogenetics N.V. Sequenzen von hepatitis-c-virus genotype 7, und deren verwendung als vorbeugende, therapeutische und diagnostische mittel
US5851759A (en) * 1996-04-19 1998-12-22 Chiron Corporation Heteroduplex tracking assay (HTA) for genotyping HCV
IT1284847B1 (it) * 1996-06-07 1998-05-22 Sorin Biomedica Diagnostics Sp Procedimento per la rivelazione di acidi nucleici specifici di hcv
CA2308762A1 (en) * 1997-11-04 1999-05-14 Roche Diagnostics Gmbh Specific and sensitive nucleic acid detection method
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
CN100400101C (zh) 2000-08-17 2008-07-09 特里帕普股份公司 包含病毒唑的疫苗及其使用方法
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6586584B2 (en) 2001-01-29 2003-07-01 Becton, Dickinson And Company Sequences and methods for detection of Hepatitis C virus
US7196183B2 (en) 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
US8124747B2 (en) 2003-08-29 2012-02-28 Innogenetics HCV clade and prototype sequences thereof
JP5138230B2 (ja) 2004-01-07 2013-02-06 サード・ウェーブ・テクノロジーズ・インク C型肝炎ウイルスの遺伝子型の決定方法
KR100733186B1 (ko) * 2005-05-31 2007-06-27 재단법인 목암생명공학연구소 Hcv 유전자에 특이적인 작은 간섭 rna 및 그를유효성분으로 포함하는 c형 간염 치료제
WO2009022236A2 (en) 2007-08-16 2009-02-19 Tripep Ab Immunogen platform

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989004669A1 (en) * 1987-11-18 1989-06-01 Chiron Corporation Nanbv diagnostics and vaccines
SU1645302A1 (ru) * 1989-01-05 1991-04-30 Московский Научно-Исследовательский Институт Педиатрии И Детской Хирургии Минздрава Рсфср Способ дифференциальной индикации вирусспецифических нуклеотидных последовательностей вируса герпеса простого типа 1 и 2.
HUT54896A (en) * 1989-03-17 1991-04-29 Chiron Corp Process for producing aquous diagnosticum and vaccine of nanbv
DE4040339C2 (de) * 1989-12-18 1999-07-08 Wellcome Found Virales Agens
WO1991014779A1 (fr) * 1990-03-28 1991-10-03 Mitsui Toatsu Chemicals, Incorporated Diagnostic du virus de l'hepatite
AU660925B2 (en) * 1990-04-06 1995-07-13 Genelabs Technologies, Inc. Hepatitis C virus epitopes
EP0933426A1 (en) * 1990-06-25 1999-08-04 The Research Foundation for Microbial Diseases of Osaka University Non-a, non-b hepatitis virus genomic cdna fragments and antigen polypeptides
FI913068A7 (fi) * 1990-06-25 1991-12-26 The Res Foundation For Microbial Ei-A-, ei-B-hepatiittiviruspartikkelit
EP0510952A1 (en) * 1991-04-26 1992-10-28 Immuno Japan Inc. Oligonucleotide primers and their application for high-fidelity detection of non-a, non-b hepatitis virus

Also Published As

Publication number Publication date
NO309532B1 (no) 2001-02-12
DE69233234D1 (de) 2003-12-04
PT100472B (pt) 1999-08-31
BG64627B1 (bg) 2005-09-30
JP2003024090A (ja) 2003-01-28
NO934019D0 (no) 1993-11-05
PL170151B1 (pl) 1996-10-31
JP2008178416A (ja) 2008-08-07
JP2003009893A (ja) 2003-01-14
JP2004290204A (ja) 2004-10-21
ATE252154T1 (de) 2003-11-15
SK284205B6 (sk) 2004-10-05
HU9303166D0 (en) 1994-03-28
KR100193801B1 (ko) 1999-06-15
EP0585398A1 (en) 1994-03-09
JP2003009892A (ja) 2003-01-14
JPH06508026A (ja) 1994-09-14
WO1992019743A3 (en) 1993-11-25
BG98200A (bg) 1995-01-31
HUT69609A (en) 1995-09-28
SK123293A3 (en) 1994-06-08
PL169880B1 (pl) 1996-09-30
CZ237793A3 (en) 1994-04-13
BG62142B1 (bg) 1999-03-31
DE69233234T2 (de) 2004-08-05
WO1992019743A2 (en) 1992-11-12
JP2003009891A (ja) 2003-01-14
HU227548B1 (en) 2011-08-29
FI934937A0 (fi) 1993-11-08
BG101876A (en) 1998-11-30
EP0585398B1 (en) 2003-10-15
RU2155228C2 (ru) 2000-08-27
CA2108466A1 (en) 1992-11-09
CZ288722B6 (cs) 2001-08-15
PT100472A (pt) 1993-08-31
ES2207633T3 (es) 2004-06-01
IE921482A1 (en) 1992-11-18
CZ288720B6 (cs) 2001-08-15
FI934937L (fi) 1994-01-05
FI115725B (fi) 2005-06-30
RO117267B1 (ro) 2001-12-28
EP1394256A3 (en) 2008-03-12
AU2155892A (en) 1992-12-21
CA2108466C (en) 2007-07-10
EP1394256A2 (en) 2004-03-03
CZ121096A3 (en) 1996-08-14
NO934019L (no) 1993-11-05
AU668355B2 (en) 1996-05-02

Similar Documents

Publication Publication Date Title
NO934019L (no) Genomiske HCV sekvenser for diagnostiske og terapeutiske formaal
WO1994025601A3 (en) New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents
Brown et al. Secondary structure of the 5′ nontranslated regions of hepatitis C virus and pestivirus genomic RNAs
RU93058449A (ru) Hcv геномные последовательности для диагностических и терапевтических целей
DK0662157T3 (da) Præparater og fremgangsmåde til behandling af Hepatitis C-virus-associerede sygdomme
MX9801715A (es) Secuencia novedosa en el extremo 3' del genoma del virus de la hepatitis c, y su uso en diagnostico y en la preparacion de composiciones terapeuticas.
NO904712D0 (no) Nanbh diagnostiske midler og vaksiner.
DE3888425D1 (de) Virale Expressionsinhibitoren.
ATE258227T1 (de) Methode zur in vitro reproduktion der rna- abhängigen rna polymerase- und terminalen nukleotidyltransferase-aktivität des hepatitis c virus (hcv)
EP0223452A3 (en) Protection of plants against viral infection
EP0331939A3 (en) Method and compositions for conferring resistance to retroviral infection
FI955224A0 (fi) Hepatiitti-C-virustyypit 4,5 ja 6
YU37502A (sh) Infektivni klonovi
ATE309367T1 (de) Nukleotid- und aminosäuresequenzen der gene des hüllproteins 1 und des kernproteins von hepatitis c virus
IL108779A (en) Polyribozyme capable of conferring viral resistance to plants, and resistant plants producing said riboyzme
Delisse et al. Sequence analysis of the putative structural genes of hepatitis C virus from Japanese and European origin
WO1999055366A8 (en) Chimeras of hepatitis c virus and bovine viral diarrhea virus
Wong et al. Molecular cloning and nucleotide sequence of 3′-terminal region of classical swine fever virus LPC vaccine strain
ATE389726T1 (de) Infektiöse vektoren und pflanzenklone, die sich von turnip mosaikvirus herleiten
ATE135404T1 (de) Nukleinsäurefragmente und vom hhv6/sie virusgenom abgeleitete diagnosemittel sowie verfahren zur diagnose von hhv6 infektionen
RU97121351A (ru) Способ репродуцирования in vitro рнк-зависимых рнк полимеразной и терминальной нуклеотидилтрансферазной активностей, кодируемых вирусом гепатита с (hcv)
DE3877212D1 (de) Antivirale anwendung von alpha-oligonucleotiden.
RU92016478A (ru) Способ диагностики гепатита, способ лечения гепатита