DK0535034T3 - Farmaceutisk aktive benzoquinazolinforbindelser - Google Patents

Farmaceutisk aktive benzoquinazolinforbindelser

Info

Publication number
DK0535034T3
DK0535034T3 DK91910823T DK91910823T DK0535034T3 DK 0535034 T3 DK0535034 T3 DK 0535034T3 DK 91910823 T DK91910823 T DK 91910823T DK 91910823 T DK91910823 T DK 91910823T DK 0535034 T3 DK0535034 T3 DK 0535034T3
Authority
DK
Denmark
Prior art keywords
pharmaceutically active
benzoquinazoline
compounds
benzoquinazoline compounds
pharmaceutically
Prior art date
Application number
DK91910823T
Other languages
Danish (da)
English (en)
Inventor
William Pendergast
Scott Howard Dickerson
Julius Vass Johnson
Robert Ferone
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of DK0535034T3 publication Critical patent/DK0535034T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK91910823T 1990-06-19 1991-06-18 Farmaceutisk aktive benzoquinazolinforbindelser DK0535034T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909013615A GB9013615D0 (en) 1990-06-19 1990-06-19 Pharmaceutical compounds
PCT/GB1991/000977 WO1991019700A1 (en) 1990-06-19 1991-06-18 Pharmaceutically active benzoquinazoline compounds

Publications (1)

Publication Number Publication Date
DK0535034T3 true DK0535034T3 (da) 2002-12-09

Family

ID=10677828

Family Applications (2)

Application Number Title Priority Date Filing Date
DK91910823T DK0535034T3 (da) 1990-06-19 1991-06-18 Farmaceutisk aktive benzoquinazolinforbindelser
DK02075192T DK1199307T3 (da) 1990-06-19 1991-06-18 Farmaceutisk aktive benzoquinazolinforbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK02075192T DK1199307T3 (da) 1990-06-19 1991-06-18 Farmaceutisk aktive benzoquinazolinforbindelser

Country Status (26)

Country Link
US (4) US6090941A (ko)
EP (2) EP1199307B1 (ko)
JP (1) JP2966929B2 (ko)
KR (1) KR0183042B1 (ko)
CN (1) CN1049215C (ko)
AP (1) AP218A (ko)
AT (2) ATE222243T1 (ko)
AU (1) AU639815B2 (ko)
CA (1) CA2085589C (ko)
CS (1) CS186391A3 (ko)
DE (2) DE69133088T2 (ko)
DK (2) DK0535034T3 (ko)
ES (2) ES2178632T3 (ko)
FI (1) FI925778A0 (ko)
GB (1) GB9013615D0 (ko)
HU (2) HUT62273A (ko)
IE (1) IE912073A1 (ko)
IL (1) IL98542A (ko)
MC (1) MC2290A1 (ko)
MY (1) MY107001A (ko)
NO (1) NO924929D0 (ko)
NZ (1) NZ238582A (ko)
PL (1) PL169927B1 (ko)
PT (1) PT98021B (ko)
WO (1) WO1991019700A1 (ko)
ZA (1) ZA914676B (ko)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9013615D0 (en) 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
US6762188B1 (en) 1990-06-19 2004-07-13 Smithkline Beecham Corporation Pharmaceutically active benzoquinazoline compounds
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
GB9226842D0 (en) * 1992-12-23 1993-02-17 Wellcome Found Pharmaceutical compounds
GB9408936D0 (en) * 1994-05-05 1994-06-22 Cancer Res Inst Anti-cancer compounds
US6420344B1 (en) 1999-03-16 2002-07-16 The Regents Of The University Of California Glycosylated polyamines
US6531454B1 (en) 1999-03-16 2003-03-11 The Regents Of The University Of California Glycosylated polyamines and methods of use therefor
KR100851957B1 (ko) 2000-06-09 2008-08-12 오에스아이 파마슈티컬스, 인코포레이티드 벤조퀴나졸린 티미딜레이트 신타제 억제제의 리포솜 제형
RU2004112771A (ru) * 2001-09-26 2005-10-10 Байер Фармасьютикалс Корпорейшн (US) Производные 1, 8-нафтиридина как противодиабетические средства
CN100434425C (zh) * 2005-03-09 2008-11-19 首都师范大学 4-喹唑啉酮衍生物及其在抗肿瘤药物中的应用
EP1754484A1 (en) 2005-08-17 2007-02-21 Dan Stoicescu Condensed pyrimidine derivatives as inhibitors of foic acid-dependent enzymes
KR20080074207A (ko) 2005-12-05 2008-08-12 닛토덴코 가부시키가이샤 폴리글루타메이트-아미노산 콘쥬게이트 및 이의 제조 방법
GB0525069D0 (en) * 2005-12-08 2006-01-18 Novartis Ag Organic compounds
WO2008041118A2 (en) 2006-10-04 2008-04-10 Pfizer Products Inc. Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists
EP1958632A1 (en) 2007-02-14 2008-08-20 Dan Stoicescu Use of condensed pyrimidine derivatives for the treatment of autoimmune and inflammatory diseases
CN101730549B (zh) * 2007-05-09 2015-12-09 日东电工株式会社 与铂类药物结合的聚合物
EP2155253A2 (en) * 2007-05-09 2010-02-24 Nitto Denko Corporation Polyglutamate conjugates and polyglutamate-amino acid conjugates having a plurality of drugs
US8197828B2 (en) * 2007-05-09 2012-06-12 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
US8146622B2 (en) 2007-08-20 2012-04-03 Ford Global Technologies, Llc Switch and hose-valve connection arrangement for vehicle temporary mobility kit
US8517760B2 (en) 2007-08-20 2013-08-27 Ford Global Technologies, Llc Cord wrap and power plug receptacle arrangement for inflator
WO2010138955A2 (en) 2009-05-29 2010-12-02 University Of Florida Research Foundation, Inc. Methods and compositions for treating neoplasia
CN101580501B (zh) * 2009-06-01 2011-03-09 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮的合成方法及其中间体
WO2011078226A1 (ja) * 2009-12-22 2011-06-30 協和発酵キリン株式会社 三環系化合物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UST862021I4 (en) * 1969-01-27 1969-05-27 Defensive publication
ZA72442B (en) * 1971-02-05 1972-10-25 Apaw Sa Automatic ice-cream machine
DE3069468D1 (en) * 1979-12-19 1984-11-22 Nat Res Dev Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
US4814335A (en) * 1982-12-30 1989-03-21 Biomeasure, Incorporated Antiviral compounds
GB8513754D0 (en) * 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives
US4603186A (en) 1985-10-21 1986-07-29 The Standard Oil Company Tetrapolymers containing indene
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
US4902624A (en) * 1987-11-23 1990-02-20 Eastman Kodak Company Temperature cycling cuvette
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
GB9013615D0 (en) * 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
US5405851A (en) * 1990-06-19 1995-04-11 Burroughs Wellcome Co. Pharmaceutical compounds

Also Published As

Publication number Publication date
KR0183042B1 (ko) 1999-05-01
CS186391A3 (en) 1992-04-15
CA2085589C (en) 2001-12-18
ES2178632T3 (es) 2003-01-01
CN1049215C (zh) 2000-02-09
JPH05507704A (ja) 1993-11-04
CA2085589A1 (en) 1991-12-20
PT98021A (pt) 1992-04-30
GB9013615D0 (en) 1990-08-08
HUT62273A (en) 1993-04-28
EP1199307B1 (en) 2004-02-25
CN1058208A (zh) 1992-01-29
AU639815B2 (en) 1993-08-05
MY107001A (en) 1995-08-30
DE69133088D1 (de) 2002-09-19
AU8094391A (en) 1992-01-07
NO924929L (no) 1992-12-18
HU9204011D0 (en) 1993-03-29
US5663337A (en) 1997-09-02
AP9100283A0 (en) 1991-07-31
ATE260262T1 (de) 2004-03-15
DE69133371T2 (de) 2005-01-27
AP218A (en) 1992-09-27
FI925778A (fi) 1992-12-18
IL98542A (en) 1995-05-26
ES2211851T3 (es) 2004-07-16
DE69133088T2 (de) 2003-03-20
IE912073A1 (en) 1992-01-01
PT98021B (pt) 1998-11-30
NO924929D0 (no) 1992-12-18
MC2290A1 (fr) 1993-07-14
FI925778A0 (fi) 1992-12-18
EP0535034B1 (en) 2002-08-14
WO1991019700A1 (en) 1991-12-26
EP0535034A1 (en) 1993-04-07
ATE222243T1 (de) 2002-08-15
IL98542A0 (en) 1992-07-15
PL169927B1 (pl) 1996-09-30
NZ238582A (en) 1993-12-23
DK1199307T3 (da) 2004-06-14
JP2966929B2 (ja) 1999-10-25
US6306865B1 (en) 2001-10-23
DE69133371D1 (de) 2004-04-01
EP1199307A1 (en) 2002-04-24
US5661155A (en) 1997-08-26
KR930701415A (ko) 1993-06-11
ZA914676B (en) 1993-02-24
HU211265A9 (en) 1995-11-28
US6090941A (en) 2000-07-18

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