DK0421081T3 - Fremgangsmåde til fremstilling af 23-(C1-C6-alkyloxim)-LL-F28249-forbindelser - Google Patents

Fremgangsmåde til fremstilling af 23-(C1-C6-alkyloxim)-LL-F28249-forbindelser

Info

Publication number
DK0421081T3
DK0421081T3 DK90114919.5T DK90114919T DK0421081T3 DK 0421081 T3 DK0421081 T3 DK 0421081T3 DK 90114919 T DK90114919 T DK 90114919T DK 0421081 T3 DK0421081 T3 DK 0421081T3
Authority
DK
Denmark
Prior art keywords
compounds
preparation
alkyloxime
nitrobenzoyl
crystalline
Prior art date
Application number
DK90114919.5T
Other languages
Danish (da)
English (en)
Inventor
Donald Roy Maulding
Anil Kumar
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DK0421081T3 publication Critical patent/DK0421081T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Liquid Crystal Substances (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Lubricants (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK90114919.5T 1989-09-11 1990-08-03 Fremgangsmåde til fremstilling af 23-(C1-C6-alkyloxim)-LL-F28249-forbindelser DK0421081T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/405,793 US4988824A (en) 1989-09-11 1989-09-11 Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds

Publications (1)

Publication Number Publication Date
DK0421081T3 true DK0421081T3 (da) 1994-07-25

Family

ID=23605260

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90114919.5T DK0421081T3 (da) 1989-09-11 1990-08-03 Fremgangsmåde til fremstilling af 23-(C1-C6-alkyloxim)-LL-F28249-forbindelser

Country Status (28)

Country Link
US (1) US4988824A (ru)
EP (1) EP0421081B1 (ru)
JP (1) JP2939312B2 (ru)
KR (1) KR0160977B1 (ru)
CN (1) CN1028428C (ru)
AT (1) ATE107650T1 (ru)
AU (1) AU634579B2 (ru)
BG (1) BG60620B1 (ru)
BR (1) BR9004493A (ru)
CA (1) CA2024919C (ru)
DE (1) DE69010129T2 (ru)
DK (1) DK0421081T3 (ru)
ES (1) ES2057291T3 (ru)
GE (1) GEP19981003B (ru)
HK (1) HK1000095A1 (ru)
HU (1) HU206721B (ru)
IE (1) IE66030B1 (ru)
IL (1) IL95303A (ru)
LV (1) LV10503B (ru)
MD (1) MD425C2 (ru)
NZ (1) NZ235151A (ru)
PL (1) PL165332B1 (ru)
PT (1) PT95242B (ru)
RU (1) RU2030416C1 (ru)
SI (1) SI9011711A (ru)
UA (1) UA26907C2 (ru)
YU (1) YU47520B (ru)
ZA (1) ZA907186B (ru)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439924A (en) * 1991-12-23 1995-08-08 Virbac, Inc. Systemic control of parasites
AU660205B2 (en) 1991-12-23 1995-06-15 Virbac, Inc Systemic control of parasites
US5478951A (en) * 1994-06-22 1995-12-26 American Cyanamid Company Method for the purification of 23-E isomers of 23-imino derivatives of LL-F28249 compounds
ES2158292T3 (es) * 1995-02-24 2001-09-01 Novartis Ag Composicion para controlar parasitos.
DE69619894T2 (de) * 1995-06-30 2002-11-14 American Cyanamid Co., Madison Stabile Makrolide und Makrolide Imptstoff-Zusammensetzungen
US6495591B1 (en) 1997-10-02 2002-12-17 Essential Therapeutics, Inc. Fungal efflux pump inhibitors
US6762327B2 (en) 2002-04-29 2004-07-13 Wyeth Selective oxidation process with enhanced safety
US7348417B2 (en) * 2003-08-07 2008-03-25 Wyeth Method of purifying moxidectin through crystallization
AU2006203459B2 (en) * 2006-05-08 2010-02-25 Wyeth Intermediates and processes using them
AU2006203349B2 (en) * 2006-05-08 2008-01-31 Wyeth Process
AU2006203353B8 (en) * 2006-06-22 2007-12-13 Wyeth Improved oxidation process with enhanced safety and use thereof
ES2659159T3 (es) 2011-12-02 2018-03-14 Merial, Inc. Formulaciones de moxidectina inyectable de acción prolongada y nuevas formas cristalinas de moxidectina
CN104277050B (zh) * 2013-07-04 2016-05-04 北大方正集团有限公司 一种制备莫西克汀的方法
CN104017001B (zh) * 2014-06-18 2016-01-13 大连九信生物化工科技有限公司 一种化学合成莫西克汀的方法
CN104292239A (zh) * 2014-09-30 2015-01-21 大连九信生物化工科技有限公司 一种消除莫西克汀生产过程中副产物二甲基硫醚的方法
CN104628740B (zh) * 2015-02-13 2017-06-16 河北圣雪大成制药有限责任公司 一种化学合成及纯化莫西克汀的方法
CN104860961B (zh) * 2015-04-10 2017-08-04 新宇药业股份有限公司 一种制备5‑氧（对‑硝基苯甲酰）‑尼莫克汀的方法
CN106831811B (zh) * 2015-08-12 2018-10-26 内蒙古佳瑞米精细化工有限公司 一种制备高含量尼莫克汀的方法
CN114591347B (zh) * 2022-03-29 2023-03-24 河北美荷药业有限公司 莫西菌素中间体及制备方法、莫西菌素的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
AU596586B2 (en) * 1985-04-30 1990-05-10 American Cyanamid Company Chemical derivatives of antibiotics S541
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
EP0259779B1 (en) * 1986-09-12 1994-08-10 American Cyanamid Company 23-Oxo (Keto) and 23-imino Derivatives of LL-F28249 Compounds
US4855317A (en) * 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8721376D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
JP2629047B2 (ja) * 1988-05-10 1997-07-09 アメリカン・サイアナミツド・カンパニー マクロライド化合物
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
US4900758A (en) * 1989-05-11 1990-02-13 Ici Americas Inc. Novel insecticides
ES2081880T3 (es) * 1989-09-11 1996-03-16 American Cyanamid Co Derivados 13-alquil-23-imino- y 13-halo-23-imino de compuestos ll-f28249 y su uso como agentes endo- y ectoparasiticidas, insecticidas, acaricidas y nematocidas.

Also Published As

Publication number Publication date
CA2024919A1 (en) 1991-03-12
PL165332B1 (pl) 1994-12-30
HUT55019A (en) 1991-04-29
HU206721B (en) 1992-12-28
RU2030416C1 (ru) 1995-03-10
MD425C2 (ru) 1997-04-30
IL95303A (en) 1994-11-28
IE903273A1 (en) 1991-03-27
UA26907C2 (uk) 1999-12-29
JPH03141283A (ja) 1991-06-17
CN1028428C (zh) 1995-05-17
BR9004493A (pt) 1991-09-10
US4988824A (en) 1991-01-29
HK1000095A1 (en) 1997-11-21
CN1051043A (zh) 1991-05-01
AU634579B2 (en) 1993-02-25
AU6236290A (en) 1991-03-14
HU905842D0 (en) 1991-03-28
EP0421081A1 (en) 1991-04-10
IE66030B1 (en) 1995-11-29
ZA907186B (en) 1991-06-26
DE69010129T2 (de) 1995-01-26
ATE107650T1 (de) 1994-07-15
PT95242B (pt) 1997-06-30
ES2057291T3 (es) 1994-10-16
GEP19981003B (en) 1998-10-27
PT95242A (pt) 1991-05-22
IL95303A0 (en) 1991-06-30
CA2024919C (en) 2001-12-11
LV10503B (en) 1996-04-20
YU47520B (sh) 1995-10-03
DE69010129D1 (de) 1994-07-28
JP2939312B2 (ja) 1999-08-25
YU171190A (sh) 1992-07-20
BG92810A (bg) 1993-12-24
NZ235151A (en) 1992-11-25
EP0421081B1 (en) 1994-06-22
KR910006490A (ko) 1991-04-29
BG60620B1 (bg) 1995-10-31
KR0160977B1 (ko) 1998-12-01
PL286824A1 (en) 1991-08-12
LV10503A (lv) 1995-02-20
SI9011711A (sl) 1998-02-28

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