DK0416410T3 - Piperaziniocephalosporiner - Google Patents

Piperaziniocephalosporiner

Info

Publication number
DK0416410T3
DK0416410T3 DK90116330.3T DK90116330T DK0416410T3 DK 0416410 T3 DK0416410 T3 DK 0416410T3 DK 90116330 T DK90116330 T DK 90116330T DK 0416410 T3 DK0416410 T3 DK 0416410T3
Authority
DK
Denmark
Prior art keywords
alkyl
same
antibacterial
hydroxyarylpiperaziniocephalosporins
cephalosporins
Prior art date
Application number
DK90116330.3T
Other languages
Danish (da)
English (en)
Inventor
Hiroshi Onoue
Toshiro Konoike
Hiroyuki Ishitobi
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of DK0416410T3 publication Critical patent/DK0416410T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK90116330.3T 1989-09-07 1990-08-26 Piperaziniocephalosporiner DK0416410T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23263189 1989-09-07

Publications (1)

Publication Number Publication Date
DK0416410T3 true DK0416410T3 (da) 1995-05-15

Family

ID=16942341

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90116330.3T DK0416410T3 (da) 1989-09-07 1990-08-26 Piperaziniocephalosporiner

Country Status (7)

Country Link
US (1) US5143910A (ja)
EP (1) EP0416410B1 (ja)
JP (1) JP2969283B2 (ja)
KR (1) KR0158452B1 (ja)
AT (1) ATE114658T1 (ja)
DE (1) DE69014490T2 (ja)
DK (1) DK0416410T3 (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0492277A3 (en) * 1990-12-20 1992-10-14 F. Hoffmann-La Roche Ag Cephalosporin derivatives
EP0550775A1 (en) * 1992-01-07 1993-07-14 F. Hoffmann-La Roche Ag Cephalosporin derivatives
JP3081773B2 (ja) * 1995-03-31 2000-08-28 株式会社資生堂 Ｎ−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤
JP4189043B2 (ja) * 1996-09-30 2008-12-03 株式会社資生堂 Ｎ−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤
DE69836559T2 (de) * 1997-09-29 2007-09-13 Aventis Pharmaceuticals Inc. Aminoalkylphenol-derivate zur behandlung von depression und gedächtnis-funktionsstörung
US6479495B1 (en) 1997-09-29 2002-11-12 Aventis Pharmaceuticals Inc. Aminoalkylphenol derivatives and related compounds
AU2004264342A1 (en) * 2003-08-05 2005-02-24 Georgetown University Sigma-1 receptor ligand with acetylcholinesterase inhibition properties
US20060247248A1 (en) * 2003-08-05 2006-11-02 Vassilios Papadopoulos Sigma-1 receptor ligand with acetylcholinesterase
US20090053137A1 (en) * 2006-03-15 2009-02-26 Moore Dennis A Chelating Conjugates Having a Substituted Aromatic Moiety and Derivatives Thereof
CA2702257C (en) 2007-10-09 2016-07-12 Sopharmia, Inc. Broad spectrum beta-lactamase inhibitors
BRPI0921701B8 (pt) 2008-10-31 2022-06-07 Shionogi & Co Cefarosporina tendo um grupo catecol, seu uso e composição farmacêutica que a compreende
WO2011125966A1 (ja) * 2010-04-05 2011-10-13 塩野義製薬株式会社 擬似カテコール基を有するセフェム化合物
KR20130018845A (ko) * 2010-04-05 2013-02-25 시오노기세야쿠 가부시키가이샤 카테콜기를 갖는 세펨 화합물
WO2011136268A1 (ja) * 2010-04-28 2011-11-03 塩野義製薬株式会社 新規なセフェム誘導体
WO2012147773A1 (ja) 2011-04-28 2012-11-01 塩野義製薬株式会社 カテコールまたは擬似カテコール構造を有する新規セフェム化合物
JP2014513116A (ja) 2011-05-02 2014-05-29 ゾエティス・エルエルシー 抗菌剤として有用な新規セファロスポリン
CN103619853A (zh) 2011-06-27 2014-03-05 盐野义制药株式会社 具有吡啶鎓基的头孢烯化合物
CN103958527A (zh) 2011-10-04 2014-07-30 盐野义制药株式会社 具有儿茶酚基团的头孢烯衍生物
KR20150076223A (ko) 2012-10-29 2015-07-06 시오노기세야쿠 가부시키가이샤 2-알킬 세펨 화합물을 위한 중간체의 제조 방법
UY35103A (es) 2012-10-29 2014-05-30 Glaxo Group Ltd Compuestos de cefem 2-sustituidos
BR112022004107A2 (pt) 2019-09-06 2022-05-31 Nabriva Therapeutics GmbH Conjugados de cefalosporina de sideróforo e seus usos
US20230121689A1 (en) 2020-01-22 2023-04-20 Shanghai Senhui Medicine Co., Ltd. Cephalosporin antibacterial compound and pharmaceutical application thereof
JP2024503656A (ja) 2021-01-12 2024-01-26 上海森▲輝▼医▲葯▼有限公司 セファロスポリン系抗菌化合物及びその調製方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5285187A (en) * 1976-01-08 1977-07-15 Shionogi & Co Ltd Antibacterials against pseudomonas aeruginosa
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
JPS6117589A (ja) * 1984-07-03 1986-01-25 Meiji Seika Kaisha Ltd 新規セフアロスポリン誘導体及びその製造法
US4785090A (en) * 1984-02-23 1988-11-15 Meiji Seika Kaisha, Ltd. Cephalosporin derivatives
US4880795A (en) * 1984-05-22 1989-11-14 Bayer Aktiengesellschaft Cephalosporins
IL77458A (en) * 1985-01-14 1990-07-26 Eisai Co Ltd Cephem derivatives,their production and antibacterial compositions containing them and certain novel intermediates therefor
ZA86405B (en) * 1985-01-31 1986-09-24 Yamanouchi Pharma Co Ltd Cephalosporin compounds and slats thereof,and their production
DE3506159A1 (de) * 1985-02-22 1986-08-28 Bayer Ag, 5090 Leverkusen Neue cephalosporine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
JPS6230786A (ja) * 1985-04-11 1987-02-09 Eisai Co Ltd ３−（キヌクリジニオ）メチル−３−セフエム誘導体
JPS625961A (ja) * 1985-07-01 1987-01-12 Meiji Seika Kaisha Ltd 酸性基を有するピリドチオン類化合物および該化合物より誘導される新規なセフアロスポリン誘導体
DE3541095A1 (de) * 1985-11-21 1987-05-27 Bayer Ag Neue cephalosporine, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel
JPS62209082A (ja) * 1986-03-11 1987-09-14 Banyu Pharmaceut Co Ltd セフアロスポリン誘導体
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
US4782155A (en) * 1986-03-19 1988-11-01 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
CA1296012C (en) * 1986-03-19 1992-02-18 Susumu Nakagawa 6,7-dihydroxy-isoquinoline derivatives
EP0272827A3 (en) * 1986-12-23 1990-02-07 ZENECA Pharma S.A. 3-heterocyclicthiomethyl cephalosphorins
DE3711343A1 (de) * 1987-04-03 1988-10-20 Bayer Ag Cephalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
PH25965A (en) * 1988-06-06 1992-01-13 Fujisawa Pharmaceutical Co New cephem compounds which have antimicrobial activities

Also Published As

Publication number Publication date
JPH03173893A (ja) 1991-07-29
DE69014490D1 (de) 1995-01-12
KR0158452B1 (ko) 1998-12-01
KR910006303A (ko) 1991-04-29
ATE114658T1 (de) 1994-12-15
JP2969283B2 (ja) 1999-11-02
EP0416410A1 (en) 1991-03-13
EP0416410B1 (en) 1994-11-30
US5143910A (en) 1992-09-01
DE69014490T2 (de) 1995-04-20

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