DK0416410T3 - Piperaziniocephalosporiner - Google Patents
PiperaziniocephalosporinerInfo
- Publication number
- DK0416410T3 DK0416410T3 DK90116330.3T DK90116330T DK0416410T3 DK 0416410 T3 DK0416410 T3 DK 0416410T3 DK 90116330 T DK90116330 T DK 90116330T DK 0416410 T3 DK0416410 T3 DK 0416410T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- same
- antibacterial
- hydroxyarylpiperaziniocephalosporins
- cephalosporins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23263189 | 1989-09-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0416410T3 true DK0416410T3 (da) | 1995-05-15 |
Family
ID=16942341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90116330.3T DK0416410T3 (da) | 1989-09-07 | 1990-08-26 | Piperaziniocephalosporiner |
Country Status (7)
Country | Link |
---|---|
US (1) | US5143910A (da) |
EP (1) | EP0416410B1 (da) |
JP (1) | JP2969283B2 (da) |
KR (1) | KR0158452B1 (da) |
AT (1) | ATE114658T1 (da) |
DE (1) | DE69014490T2 (da) |
DK (1) | DK0416410T3 (da) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0492277A3 (en) * | 1990-12-20 | 1992-10-14 | F. Hoffmann-La Roche Ag | Cephalosporin derivatives |
EP0550775A1 (en) * | 1992-01-07 | 1993-07-14 | F. Hoffmann-La Roche Ag | Cephalosporin derivatives |
JP3081773B2 (ja) * | 1995-03-31 | 2000-08-28 | 株式会社資生堂 | N−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤 |
JP4189043B2 (ja) * | 1996-09-30 | 2008-12-03 | 株式会社資生堂 | N−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤 |
US6479495B1 (en) | 1997-09-29 | 2002-11-12 | Aventis Pharmaceuticals Inc. | Aminoalkylphenol derivatives and related compounds |
EP1032559B1 (en) * | 1997-09-29 | 2006-11-29 | Aventis Pharmaceuticals Inc. | Aminoalkylphenol derivatives for treating depression and memory dysfunction |
US20060247248A1 (en) * | 2003-08-05 | 2006-11-02 | Vassilios Papadopoulos | Sigma-1 receptor ligand with acetylcholinesterase |
EP1651235A4 (en) * | 2003-08-05 | 2008-12-17 | Samaritan Pharmaceuticals Inc | SIGMA-1 RECEPTOR LIGAND WITH ACETYLCHOLINESTERASE-INHIBITORY PROPERTIES |
US20090053137A1 (en) * | 2006-03-15 | 2009-02-26 | Moore Dennis A | Chelating Conjugates Having a Substituted Aromatic Moiety and Derivatives Thereof |
CA2935651A1 (en) | 2007-10-09 | 2009-04-16 | Gladius Pharmaceuticals Corporation | Broad spectrum beta-lactamase inhibitors |
ME02666B (me) | 2008-10-31 | 2017-06-20 | Shionogi & Co | Cefalosporin sa kateholskom grupom |
JP5852559B2 (ja) * | 2010-04-05 | 2016-02-03 | 塩野義製薬株式会社 | 擬似カテコール基を有するセフェム化合物 |
AU2011236933A1 (en) * | 2010-04-05 | 2013-05-02 | Shionogi & Co., Ltd. | Cephem compound having catechol group |
JP5852562B2 (ja) * | 2010-04-28 | 2016-02-03 | 塩野義製薬株式会社 | 新規なセフェム誘導体 |
JP6006201B2 (ja) * | 2011-04-28 | 2016-10-12 | 塩野義製薬株式会社 | カテコールまたは擬似カテコール構造を有する新規セフェム化合物 |
JP2014513116A (ja) | 2011-05-02 | 2014-05-29 | ゾエティス・エルエルシー | 抗菌剤として有用な新規セファロスポリン |
CN103619853A (zh) | 2011-06-27 | 2014-03-05 | 盐野义制药株式会社 | 具有吡啶鎓基的头孢烯化合物 |
WO2013051597A1 (ja) | 2011-10-04 | 2013-04-11 | 塩野義製薬株式会社 | カテコール基を有するセフェム誘導体 |
KR20150076223A (ko) | 2012-10-29 | 2015-07-06 | 시오노기세야쿠 가부시키가이샤 | 2-알킬 세펨 화합물을 위한 중간체의 제조 방법 |
UY35103A (es) | 2012-10-29 | 2014-05-30 | Glaxo Group Ltd | Compuestos de cefem 2-sustituidos |
KR20220061163A (ko) | 2019-09-06 | 2022-05-12 | 나브리바 테라퓨틱스 게엠베하 | 사이드로포어 세팔로스포린 접합체 및 이의 용도 |
JP2023511188A (ja) | 2020-01-22 | 2023-03-16 | 上海森輝医薬有限公司 | セファロスポリン系抗菌化合物及びその医薬的応用 |
EP4279491A4 (en) | 2021-01-12 | 2024-07-24 | Shanghai Senhui Medicine Co Ltd | CEPHALOSPORIN ANTIBACTERIAL COMPOUND AND PREPARATION METHOD THEREFOR |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5285187A (en) * | 1976-01-08 | 1977-07-15 | Shionogi & Co Ltd | Antibacterials against pseudomonas aeruginosa |
US4525473A (en) * | 1983-03-30 | 1985-06-25 | Bristol-Myers Company | Cephalosporins |
JPS6117589A (ja) * | 1984-07-03 | 1986-01-25 | Meiji Seika Kaisha Ltd | 新規セフアロスポリン誘導体及びその製造法 |
KR920004820B1 (ko) * | 1984-02-23 | 1992-06-18 | 메이지제과 주식회사 | 새로운 세팔로스포린 유도체의 제조방법 |
US4880795A (en) * | 1984-05-22 | 1989-11-14 | Bayer Aktiengesellschaft | Cephalosporins |
IL77458A (en) * | 1985-01-14 | 1990-07-26 | Eisai Co Ltd | Cephem derivatives,their production and antibacterial compositions containing them and certain novel intermediates therefor |
ZA86405B (en) * | 1985-01-31 | 1986-09-24 | Yamanouchi Pharma Co Ltd | Cephalosporin compounds and slats thereof,and their production |
DE3506159A1 (de) * | 1985-02-22 | 1986-08-28 | Bayer Ag, 5090 Leverkusen | Neue cephalosporine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
JPS6230786A (ja) * | 1985-04-11 | 1987-02-09 | Eisai Co Ltd | 3−(キヌクリジニオ)メチル−3−セフエム誘導体 |
JPS625961A (ja) * | 1985-07-01 | 1987-01-12 | Meiji Seika Kaisha Ltd | 酸性基を有するピリドチオン類化合物および該化合物より誘導される新規なセフアロスポリン誘導体 |
DE3541095A1 (de) * | 1985-11-21 | 1987-05-27 | Bayer Ag | Neue cephalosporine, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel |
JPS62209082A (ja) * | 1986-03-11 | 1987-09-14 | Banyu Pharmaceut Co Ltd | セフアロスポリン誘導体 |
US4782155A (en) * | 1986-03-19 | 1988-11-01 | Banyu Pharmaceutical Co., Ltd. | Cephalosporin derivatives, processes for their preparation and antibacterial agents |
US4814328A (en) * | 1986-03-19 | 1989-03-21 | Banyu Pharmaceutical Co., Ltd. | Cephalosporin derivatives, and antibacterial agents |
DE3775798D1 (de) * | 1986-03-19 | 1992-02-20 | Banyu Pharma Co Ltd | Cephalosporinverbindungen, verfahren zu ihrer herstellung und antibakterielle mittel. |
EP0272827A3 (en) * | 1986-12-23 | 1990-02-07 | ZENECA Pharma S.A. | 3-heterocyclicthiomethyl cephalosphorins |
DE3711343A1 (de) * | 1987-04-03 | 1988-10-20 | Bayer Ag | Cephalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
PH25965A (en) * | 1988-06-06 | 1992-01-13 | Fujisawa Pharmaceutical Co | New cephem compounds which have antimicrobial activities |
-
1990
- 1990-08-23 US US07/571,411 patent/US5143910A/en not_active Expired - Fee Related
- 1990-08-26 AT AT90116330T patent/ATE114658T1/de not_active IP Right Cessation
- 1990-08-26 EP EP90116330A patent/EP0416410B1/en not_active Expired - Lifetime
- 1990-08-26 DE DE69014490T patent/DE69014490T2/de not_active Expired - Fee Related
- 1990-08-26 DK DK90116330.3T patent/DK0416410T3/da active
- 1990-09-06 JP JP2237983A patent/JP2969283B2/ja not_active Expired - Fee Related
- 1990-09-07 KR KR1019900014162A patent/KR0158452B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH03173893A (ja) | 1991-07-29 |
JP2969283B2 (ja) | 1999-11-02 |
EP0416410B1 (en) | 1994-11-30 |
KR0158452B1 (ko) | 1998-12-01 |
KR910006303A (ko) | 1991-04-29 |
EP0416410A1 (en) | 1991-03-13 |
US5143910A (en) | 1992-09-01 |
DE69014490T2 (de) | 1995-04-20 |
ATE114658T1 (de) | 1994-12-15 |
DE69014490D1 (de) | 1995-01-12 |
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