DK0409549T3 - Forbedret saccharose-6-esterchlorering - Google Patents

Forbedret saccharose-6-esterchlorering

Info

Publication number
DK0409549T3
DK0409549T3 DK90307784.0T DK90307784T DK0409549T3 DK 0409549 T3 DK0409549 T3 DK 0409549T3 DK 90307784 T DK90307784 T DK 90307784T DK 0409549 T3 DK0409549 T3 DK 0409549T3
Authority
DK
Denmark
Prior art keywords
improved sucrose
ester chlorination
chlorination
ester
sucrose
Prior art date
Application number
DK90307784.0T
Other languages
Danish (da)
English (en)
Inventor
Robert E Walkup
Juan L Navia
Nicholas M Vernon
Original Assignee
Noramco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23507711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0409549(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Noramco Inc filed Critical Noramco Inc
Application granted granted Critical
Publication of DK0409549T3 publication Critical patent/DK0409549T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK90307784.0T 1989-07-18 1990-07-17 Forbedret saccharose-6-esterchlorering DK0409549T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/382,147 US4980463A (en) 1989-07-18 1989-07-18 Sucrose-6-ester chlorination

Publications (1)

Publication Number Publication Date
DK0409549T3 true DK0409549T3 (da) 1996-02-12

Family

ID=23507711

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90307784.0T DK0409549T3 (da) 1989-07-18 1990-07-17 Forbedret saccharose-6-esterchlorering

Country Status (26)

Country Link
US (1) US4980463A (fi)
EP (1) EP0409549B1 (fi)
JP (1) JP3183506B2 (fi)
KR (1) KR0144344B1 (fi)
AR (1) AR247401A1 (fi)
AT (1) ATE133175T1 (fi)
AU (1) AU625908B2 (fi)
CA (1) CA2021632C (fi)
DE (1) DE69024868T2 (fi)
DK (1) DK0409549T3 (fi)
ES (1) ES2088973T3 (fi)
FI (1) FI95802C (fi)
GR (1) GR1002037B (fi)
IE (1) IE69961B1 (fi)
IL (1) IL94994A (fi)
MX (1) MX164442B (fi)
NO (1) NO175532C (fi)
NZ (1) NZ234468A (fi)
PE (1) PE21591A1 (fi)
PH (1) PH26799A (fi)
PT (1) PT94719B (fi)
RU (1) RU1836377C (fi)
TR (1) TR28705A (fi)
TW (1) TW219939B (fi)
YU (1) YU47948B (fi)
ZA (1) ZA905615B (fi)

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US5470969A (en) * 1990-08-27 1995-11-28 Mcneil-Ppc, Inc. Catalyzed sucrose-6-ester process
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IL114551A0 (en) 1994-07-11 1995-11-27 Us Agriculture Chemically synthesized sugar esters for the control of soft bodied arthropods
US6608039B1 (en) 1994-07-11 2003-08-19 The United States Of America As Represented By The Secretary Of Agriculture Chemically synthesized sugar esters for the control of soft-bodied arthropods
US5498709A (en) 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
KR100405203B1 (ko) * 1996-05-23 2004-02-14 비앤티엔지니어링(주) 암거배수로관
US5977349A (en) * 1997-02-13 1999-11-02 Mcneil-Ppc, Inc. Chromatographic purification of chlorinated sucrose
WO1999060006A1 (en) * 1998-05-15 1999-11-25 Zhbankov Rostislav G Method of preparation 4,1´,6´-trichloro-4,1´,6´-trideoxygalactosucrose
DE19924770A1 (de) * 1999-05-29 2000-12-21 Buna Sow Leuna Olefinverb Gmbh Verfahren zur Herstellung von Polyetherpolyolen aus Polysacchariden und deren Verwendung für die Herstellung von PUR-Schäumen
US6500973B2 (en) 2000-06-02 2002-12-31 Eastman Chemical Company Extractive solution crystallization of chemical compounds
ATE387457T1 (de) * 2000-08-25 2008-03-15 Eastman Chem Co Verfahren zur herstellung von disaccharid und trisaccharid c6-c12 fettsäure-estern mit hohem alpha gehalt und materialien davon
US6667397B2 (en) * 2000-08-25 2003-12-23 Eastman Chemical Company Methods of preparing disaccharide and trisaccharide C6-C12 fatty acid esters with high alpha content and materials therefrom
AU2691802A (en) 2000-11-17 2002-05-27 Mcneil Ppc Inc Improved sucralose composition and process for its preparation
US7049435B2 (en) 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose
US6998480B2 (en) 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US6890581B2 (en) * 2002-04-05 2005-05-10 Tate & Lyle Public Limited Company Methods for buffer stabilized aqueous deacylation
US20040170735A2 (en) * 2002-04-05 2004-09-02 Mcneil-Ppc, Inc. Methods and compositions for altering the sweetness delivery profile of sucralose
US20040086605A1 (en) * 2002-10-30 2004-05-06 Sox Thomas E. Composition for delivering a high intensity sweetener
US6943248B2 (en) * 2003-04-30 2005-09-13 Tate & Lyle Public Limited Company Crystalline form of sucralose, and method for producing it
CN1176094C (zh) * 2003-05-23 2004-11-17 广东省食品工业研究所 一种三氯蔗糖的合成方法
WO2005087020A1 (en) * 2004-03-05 2005-09-22 Richmond Chemical Corporation High-intensity sweetener-polyol compositions
JP2007529505A (ja) * 2004-03-19 2007-10-25 ファームド メディケア プライベート リミティッド 塩素化スクロース製造の改良された方法
US20050214425A1 (en) * 2004-03-23 2005-09-29 Roma Vazirani Sugar substitute prepared with nutritive and high-intensity sweeteners
CN101098972A (zh) * 2004-12-10 2008-01-02 法马德医疗保险私人有限公司 硅烷化硅胶色谱纯化6-乙酰基-4,1',6'三氯半乳蔗糖和4,1',6'三氯半乳蔗糖的改良方法
CN101098970B (zh) * 2004-12-10 2010-05-12 V.B.医疗保险私人有限公司 通过在6-乙酰基-4,1',6'三氯半乳蔗糖和4,1',6'三氯半乳蔗糖的有机溶剂提取物的浓缩过程中直接加入碳酸盐和碳酸氢盐来调节pH的方法
WO2006061855A2 (en) * 2004-12-10 2006-06-15 Pharmed Medicare Private Limited Salts assisted selective extraction of 6-acetyl-4.1', 6' trichlorogalactosucrose and 4, 1 ', 6' trichlorogalactosucrose from aqueous reaction mixture
KR20070113194A (ko) * 2005-01-03 2007-11-28 팜드 메디케어 프리베이트 리미티드 염소화 시약의 동시 첨가에 의한 수크로스-6-에스테르염소화
US20060188629A1 (en) * 2005-01-21 2006-08-24 Greg Liesen Method for the purification of sucralose
CN101166748A (zh) * 2005-02-22 2008-04-23 法马德医疗保险私人有限公司 在生产氯化蔗糖、其前体和衍生物过程的不同步骤中的分子分离方法
US20060205936A1 (en) * 2005-03-14 2006-09-14 Sl Laboratories, Llc Chlorination of Sucrose-6-esters
US20060247180A1 (en) * 2005-04-29 2006-11-02 Bergey James L Purgative composition and uses thereof
WO2007017891A2 (en) * 2005-05-04 2007-02-15 Pharmed Medicare Private Limited Generation of phosphorus oxychloride as by-product from phosphorus pentachloride and dmf and its use for chlorination reaction by converting into vilsmeier-haack reagent.
US20090030193A1 (en) * 2005-05-04 2009-01-29 Pharmed Medicare Private Limited Synthesis of Vilsmeier Haack Reagent from Di(Trichlo-Romethyl) Carbonate for Chlorination Reaction
US20060276639A1 (en) * 2005-06-01 2006-12-07 Healthy Brands, Llc Conversion of sucralose-6-ester to sucralose
WO2007017899A2 (en) * 2005-06-01 2007-02-15 Pharmed Medicare Private Limited Method for purification of chlorinated sucrose derivatives by solvent extraction
CN101268091A (zh) * 2005-09-22 2008-09-17 法马德医疗保险私人有限公司 从无水氯化反应物料制备6-o-酰基氯化蔗糖的新型方法
US20070100139A1 (en) * 2005-10-31 2007-05-03 Healthy Brands, Llc Methods for chlorinating sucrose-6-ester
US7741477B2 (en) * 2006-01-10 2010-06-22 Alembic Limited Process for purification of sucralose
CN101395167A (zh) * 2006-02-28 2009-03-25 V.B.医疗保险私人有限公司 用于使用氯化亚砜氯化糖的新型氯化试剂以及新方法
CN100418976C (zh) * 2006-04-03 2008-09-17 广州科宏食品添加物有限公司 一种三氯蔗糖的制备方法
CN100402541C (zh) * 2006-06-15 2008-07-16 浙江工业大学 一种三氯蔗糖-6-乙酯的合成方法
CN101092438A (zh) * 2006-06-22 2007-12-26 南京莱因医药科技有限公司 6－o－苯甲酰三氯半乳型蔗糖四乙酯的制备方法
WO2008004246A1 (en) * 2006-07-06 2008-01-10 Alembic Limited An improved process for the preparation of sucralose of high purity
CN100420697C (zh) * 2006-08-30 2008-09-24 河北苏科瑞科技有限公司 一种制备蔗糖-6-有机酸酯的方法
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US20080103295A1 (en) * 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
US20080227971A1 (en) * 2007-01-19 2008-09-18 Leinhos Duane A Deacylation of sucralose-6-acylates
GB0702857D0 (en) * 2007-01-19 2007-03-28 Tate & Lyle Plc Improved sucralose production method
CN101260127B (zh) * 2007-03-06 2011-04-20 盐城捷康三氯蔗糖制造有限公司 由三氯蔗糖-6-乙酯脱乙酰基合成三氯蔗糖的方法
US20080300392A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
US20080300401A1 (en) * 2007-06-04 2008-12-04 Polymed Therapeutics, Inc. Novel chlorination process for preparing sucralose
AR070082A1 (es) * 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
US7932380B2 (en) * 2008-03-06 2011-04-26 Wanhe International (Group) Co. Ltd. Process for the preparation of sucralose
US8557976B2 (en) * 2008-03-13 2013-10-15 Tate & Lyle Technology Limited Microbial consortia and methods for their use
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US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
US20090299055A1 (en) * 2008-04-03 2009-12-03 Tate & Lyle Technology Limited Purification of Sucralose Containing Feed Streams for Sucralose Crystallization
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US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
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GB2469157B (en) 2009-03-30 2011-07-06 John Kerr Process for removing dimethylamine during sucralose production
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GB2471348B (en) * 2009-06-22 2011-12-14 Tate & Lyle Technology Ltd A method for producing sucralose-6-acylate
GB2474311B (en) * 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
WO2012025937A1 (en) * 2010-08-25 2012-03-01 Ramamohan Rao Davuluri Improved process for preparation of sugammadex
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GB201110520D0 (en) 2011-05-10 2011-08-03 Tate & Lyle Technology Ltd Extraction of carboxylic acids with tin compounds
JP5679447B2 (ja) * 2011-06-20 2015-03-04 第一工業製薬株式会社 ショ糖ベンゾエート組成物の製造方法
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CN102964396B (zh) * 2012-10-26 2015-11-18 溧阳维信生物科技有限公司 一种三氯蔗糖-6-乙酯重结晶的方法
JP6109531B2 (ja) * 2012-11-02 2017-04-05 第一工業製薬株式会社 溶媒の除去方法
CN103145772A (zh) * 2013-03-26 2013-06-12 山东金城柯瑞化学有限公司 三氯蔗糖的制备方法
US10227367B2 (en) 2013-12-16 2019-03-12 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
WO2016020635A1 (en) 2014-08-08 2016-02-11 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
CN104387427A (zh) * 2014-10-30 2015-03-04 安徽金禾实业股份有限公司 一种三氯蔗糖的生产方法
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
CN105131050B (zh) * 2015-07-22 2018-07-31 青岛科技大学 一种氯化剂的制备方法及其制备三氯蔗糖的方法
CN105859802B (zh) * 2016-05-14 2019-02-12 广西科技大学 一种三氯蔗糖的结晶和纯化方法
GB2551591B (en) 2016-06-23 2019-08-07 Tate & Lyle Tech Ltd Liquid-liquid extraction of DMF
MX2023003704A (es) 2020-09-30 2023-05-09 Anhui Jinhe Ind Co Ltd Método de purificación de sucralosa.
CN113699196A (zh) * 2021-08-17 2021-11-26 安徽金禾实业股份有限公司 一种蔗糖-6-乙酸酯的无水酶法催化合成方法

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US4435440A (en) * 1976-01-08 1984-03-06 Tate & Lyle Limited Sweeteners
DE2962239D1 (en) * 1978-10-18 1982-04-01 Tate & Lyle Patent Holdings A method for the preparation of 2-chloro-2-deoxy saccharides and some 2-chloro-2-deoxy saccharides
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EP0043649B1 (en) * 1980-07-08 1984-09-12 TATE & LYLE PUBLIC LIMITED COMPANY Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs)
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GB8622345D0 (en) * 1986-09-17 1986-10-22 Tate & Lyle Plc Sucrose derivatives

Also Published As

Publication number Publication date
EP0409549B1 (en) 1996-01-17
DE69024868T2 (de) 1996-07-11
IE69961B1 (en) 1996-10-16
NO175532B (no) 1994-07-18
KR0144344B1 (ko) 1998-07-01
PH26799A (en) 1992-10-13
IL94994A0 (en) 1991-06-10
JPH03218388A (ja) 1991-09-25
YU141190A (sh) 1992-07-20
IL94994A (en) 1994-06-24
DE69024868D1 (de) 1996-02-29
ATE133175T1 (de) 1996-02-15
AU625908B2 (en) 1992-07-16
KR910002885A (ko) 1991-02-26
EP0409549A2 (en) 1991-01-23
FI903603A0 (fi) 1990-07-17
FI95802B (fi) 1995-12-15
TW219939B (fi) 1994-02-01
MX164442B (es) 1992-08-13
FI95802C (fi) 1996-03-25
NO903190L (no) 1991-01-21
JP3183506B2 (ja) 2001-07-09
TR28705A (tr) 1997-01-27
NO903190D0 (no) 1990-07-17
PE21591A1 (es) 1991-07-22
NO175532C (no) 1994-10-26
NZ234468A (en) 1992-01-29
AR247401A1 (es) 1994-12-29
EP0409549A3 (en) 1992-08-26
IE902603A1 (en) 1991-02-27
US4980463A (en) 1990-12-25
AU5906990A (en) 1991-01-24
ZA905615B (en) 1992-03-25
RU1836377C (ru) 1993-08-23
GR900100537A (el) 1991-12-10
ES2088973T3 (es) 1996-10-01
GR1002037B (en) 1995-10-31
PT94719A (pt) 1991-03-20
CA2021632C (en) 2000-09-12
YU47948B (sh) 1996-07-24
PT94719B (pt) 1997-04-30
CA2021632A1 (en) 1991-01-19

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