DE904095T1 - Chimäre isoprenoidsynthasen und deren verwendungen - Google Patents

Chimäre isoprenoidsynthasen und deren verwendungen

Info

Publication number
DE904095T1
DE904095T1 DE0904095T DE97921142T DE904095T1 DE 904095 T1 DE904095 T1 DE 904095T1 DE 0904095 T DE0904095 T DE 0904095T DE 97921142 T DE97921142 T DE 97921142T DE 904095 T1 DE904095 T1 DE 904095T1
Authority
DE
Germany
Prior art keywords
isoprenoid synthase
chimeric
synthase
chimeric isoprenoid
isoprenoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0904095T
Other languages
German (de)
English (en)
Inventor
Kyoungwhan Back
Joseph Chappell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Kentucky
Original Assignee
University of Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Kentucky filed Critical University of Kentucky
Publication of DE904095T1 publication Critical patent/DE904095T1/de
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE0904095T 1996-04-12 1997-04-11 Chimäre isoprenoidsynthasen und deren verwendungen Pending DE904095T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/631,341 US5824774A (en) 1996-04-12 1996-04-12 Chimeric isoprenoid synthases and uses thereof
PCT/US1997/005986 WO1997038703A1 (en) 1996-04-12 1997-04-11 Chimeric isoprenoid synthases and uses thereof

Publications (1)

Publication Number Publication Date
DE904095T1 true DE904095T1 (de) 1999-10-07

Family

ID=24530791

Family Applications (2)

Application Number Title Priority Date Filing Date
DE0904095T Pending DE904095T1 (de) 1996-04-12 1997-04-11 Chimäre isoprenoidsynthasen und deren verwendungen
DE69715192T Expired - Fee Related DE69715192T2 (de) 1996-04-12 1997-04-11 Chimäre isoprenoidsynthasen und deren verwendungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69715192T Expired - Fee Related DE69715192T2 (de) 1996-04-12 1997-04-11 Chimäre isoprenoidsynthasen und deren verwendungen

Country Status (25)

Country Link
US (2) US5824774A (cg-RX-API-DMAC10.html)
EP (2) EP1229122A3 (cg-RX-API-DMAC10.html)
JP (4) JP2000508899A (cg-RX-API-DMAC10.html)
KR (1) KR20000005385A (cg-RX-API-DMAC10.html)
AP (1) AP808A (cg-RX-API-DMAC10.html)
AR (1) AR006638A1 (cg-RX-API-DMAC10.html)
AT (1) ATE223225T1 (cg-RX-API-DMAC10.html)
AU (1) AU2726497A (cg-RX-API-DMAC10.html)
BR (1) BR9708650A (cg-RX-API-DMAC10.html)
CA (1) CA2250712C (cg-RX-API-DMAC10.html)
CZ (1) CZ294613B6 (cg-RX-API-DMAC10.html)
DE (2) DE904095T1 (cg-RX-API-DMAC10.html)
EA (1) EA001622B1 (cg-RX-API-DMAC10.html)
ES (1) ES2132046T3 (cg-RX-API-DMAC10.html)
GR (1) GR990300025T1 (cg-RX-API-DMAC10.html)
ID (1) ID19769A (cg-RX-API-DMAC10.html)
IL (2) IL126486A0 (cg-RX-API-DMAC10.html)
IN (1) IN186316B (cg-RX-API-DMAC10.html)
OA (1) OA10895A (cg-RX-API-DMAC10.html)
PL (1) PL329404A1 (cg-RX-API-DMAC10.html)
PT (1) PT904095E (cg-RX-API-DMAC10.html)
TR (1) TR199802043T2 (cg-RX-API-DMAC10.html)
TW (1) TW509724B (cg-RX-API-DMAC10.html)
WO (1) WO1997038703A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA973108B (cg-RX-API-DMAC10.html)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8106260B2 (en) * 1996-04-12 2012-01-31 The Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US5824774A (en) * 1996-04-12 1998-10-20 Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US7186891B1 (en) * 1996-04-12 2007-03-06 University Of Kentucky, Research Foundation Plant cells and plants expressing chimeric isoprenoid synthases
US5945726A (en) * 1996-12-16 1999-08-31 Micron Technology, Inc. Lateral bipolar transistor
AR022383A1 (es) 1998-09-18 2002-09-04 Univ Kentucky Res Found Sintasas
DE60042730D1 (de) * 1999-01-05 2009-09-24 Univ Boston Verbessertes klonierungsverfahren
US6358712B1 (en) 1999-01-05 2002-03-19 Trustee Of Boston University Ordered gene assembly
US20040005673A1 (en) * 2001-06-29 2004-01-08 Kevin Jarrell System for manipulating nucleic acids
EP2281890A1 (en) 2000-07-31 2011-02-09 Danisco US Inc. Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms
JP2004532014A (ja) 2001-03-09 2004-10-21 ユニバーシティ・オブ・ケンタッキー・リサーチ・ファウンデーション チトクロームp450類及びその使用
AU2012202780B2 (en) * 2001-03-09 2014-07-03 University Of Kentucky Research Foundation Cytochrome P450s and Uses Thereof
AU2013204829B2 (en) * 2001-03-09 2013-07-04 University Of Kentucky Research Foundation Cytochrome P450s and uses thereof
US7172886B2 (en) * 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
US7192751B2 (en) * 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
US7442785B2 (en) 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
US8124811B2 (en) * 2007-03-20 2012-02-28 Allylix, Inc. Fragrance and methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one
KR20130020842A (ko) 2007-06-01 2013-02-28 더 스크립스 리서치 인스티튜트 유전적으로 변형된 광합성 생물들의 고처리량 스크리닝
US9695372B2 (en) 2007-09-11 2017-07-04 Sapphire Energy, Inc. Methods of producing organic products with photosynthetic organisms
EP2188376A4 (en) * 2007-09-11 2013-07-10 Sapphire Energy Inc MOLECULAR PRODUCTION BY PHOTOSYNTHETIC ORGANISMS
SG191671A1 (en) * 2007-12-13 2013-07-31 Danisco Us Inc Cultured cells that produce isoprene and methods for producing isoprene
US8034992B2 (en) * 2008-06-16 2011-10-11 Academia Sinica Gibberellin 2-oxidase genes and uses thereof
EP2326707B1 (en) 2008-08-12 2016-11-23 Evolva, Inc. Method for production of isoprenoids
AU2011320127B2 (en) 2010-10-29 2015-10-01 Evolva, Inc. Modified valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
WO2013110191A1 (en) 2012-01-23 2013-08-01 The University Of British Columbia Abc trepenoid transporters and methods of using the same
JP5950253B2 (ja) * 2012-02-13 2016-07-13 住友ゴム工業株式会社 イソプレノイドの製造方法、及びイソプレノイド
EP2880159A1 (en) 2012-07-30 2015-06-10 Allylix, Inc. Sclareol and labdenediol diphosphate synthase polypeptides encoding nucleic acid molecules and uses thereof
JP2015533285A (ja) 2012-11-01 2015-11-24 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア シトクロムp450およびシトクロムp450レダクターゼポリペプチド、コードする核酸分子、ならびにそれらの用途
DK2970934T3 (da) 2013-03-14 2017-11-13 Evolva Inc Valencensynthasepolypeptider, nukleinsyremolekyler, der koder derfor, og anvendelser deraf
CN111621508B (zh) * 2020-06-11 2022-07-01 云南中烟工业有限责任公司 烟草萜类合成酶NtTPS7基因及其载体与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69420957T2 (de) * 1993-04-02 2000-01-13 Pioneer Hi-Bred International, Inc. Bekämpfung von diabrotica undecimpunctata mittels limonen
CA2118071C (en) * 1993-10-28 2004-09-14 Rodney B. Croteau Dna encoding limonene synthase from mentha spicata
US5824774A (en) * 1996-04-12 1998-10-20 Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof

Also Published As

Publication number Publication date
GR990300025T1 (en) 1999-07-30
BR9708650A (pt) 1999-08-03
IL126486A (en) 2006-04-10
AR006638A1 (es) 1999-09-08
CA2250712A1 (en) 1997-10-23
ID19769A (id) 1998-07-30
KR20000005385A (ko) 2000-01-25
CZ317998A3 (cs) 1999-02-17
CZ294613B6 (cs) 2005-02-16
EP1229122A2 (en) 2002-08-07
US6072045A (en) 2000-06-06
AP9700971A0 (en) 1997-07-31
ZA973108B (en) 1997-11-04
DE69715192D1 (de) 2002-10-10
ES2132046T1 (es) 1999-08-16
PT904095E (pt) 2002-12-31
US5824774A (en) 1998-10-20
AU2726497A (en) 1997-11-07
DE69715192T2 (de) 2003-04-30
EP0904095B1 (en) 2002-09-04
WO1997038703A1 (en) 1997-10-23
PL329404A1 (en) 1999-03-29
JP2015171387A (ja) 2015-10-01
JP2015057074A (ja) 2015-03-26
EA001622B1 (ru) 2001-06-25
IN186316B (cg-RX-API-DMAC10.html) 2001-08-04
CA2250712C (en) 2008-07-08
JP2012005499A (ja) 2012-01-12
EP0904095A4 (en) 1999-07-07
TR199802043T2 (xx) 1999-01-18
HK1017275A1 (en) 1999-11-19
IL126486A0 (en) 1999-08-17
JP2000508899A (ja) 2000-07-18
ES2132046T3 (es) 2003-03-16
TW509724B (en) 2002-11-11
ATE223225T1 (de) 2002-09-15
AP808A (en) 2000-02-29
EP1229122A3 (en) 2002-10-09
OA10895A (en) 2001-10-11
EA199800917A1 (ru) 1999-04-29
EP0904095A1 (en) 1999-03-31

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