ES2132046T1 - Isoprenoide sintasas quimericas y usos de las mismas. - Google Patents
Isoprenoide sintasas quimericas y usos de las mismas.Info
- Publication number
- ES2132046T1 ES2132046T1 ES97921142T ES97921142T ES2132046T1 ES 2132046 T1 ES2132046 T1 ES 2132046T1 ES 97921142 T ES97921142 T ES 97921142T ES 97921142 T ES97921142 T ES 97921142T ES 2132046 T1 ES2132046 T1 ES 2132046T1
- Authority
- ES
- Spain
- Prior art keywords
- isoprenoid
- chemical
- domain
- synthetase
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
EN LA PRESENTE INVENCION SE DESCRIBE UN POLIPEPTIDO DE SINTETASA ISOPRENOIDE QUIMERICA QUE INCLUYE UN PRIMER DOMINIO PROCEDENTE DE UNA PRIMERA SINTETASA ISOPRENOIDE QUE SE UNE A UN SEGUNDO DOMINIO PROCEDENTE DE UNA SINTETASA ISOPRENOIDE HETEROLOGA, EN DONDE, LA SINTETASA ISOPRENOIDE QUIMERICA ES CAPAZ DE CATALIZAR LA OBTENCION DE PRODUCTOS DE REACCION ISOPRENOIDES QUE NO SE PRODUCEN EN AUSENCIA DEL SEGUNDO DOMINIO DE DICHA SINTETASA ISOPRENOIDE HETEROLOGA. TAMBIEN SE DESCRIBE UN POLIPEPTIDO DE SINTETASA ISOPRENOIDE QUIMERICA QUE INCLUYE UN DOMINIO HOMOLOGO COLOCADO ASIMETRICAMENTE, EN DONDE, DICHA SINTETASA ES CAPAZ DE CATALIZAR LA OBTENCION DE PRODUCTOS DE REACCION ISOPRENOIDES, QUE NO SE PRODUCEN CUANDO DICHO DOMINIO SE COLOCA EN LA POSICION EN QUE SE ENCUENTRA EN LA NATURALEZA EN DICHO POLIPEPTIDO DE SINTETASA ISOPRENOIDE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/631,341 US5824774A (en) | 1996-04-12 | 1996-04-12 | Chimeric isoprenoid synthases and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2132046T1 true ES2132046T1 (es) | 1999-08-16 |
ES2132046T3 ES2132046T3 (es) | 2003-03-16 |
Family
ID=24530791
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97921142T Expired - Lifetime ES2132046T3 (es) | 1996-04-12 | 1997-04-11 | Sintasas isoprenoides quimericas y usos de las mismas. |
Country Status (26)
Country | Link |
---|---|
US (2) | US5824774A (es) |
EP (2) | EP0904095B1 (es) |
JP (4) | JP2000508899A (es) |
KR (1) | KR20000005385A (es) |
AP (1) | AP808A (es) |
AR (1) | AR006638A1 (es) |
AT (1) | ATE223225T1 (es) |
AU (1) | AU2726497A (es) |
BR (1) | BR9708650A (es) |
CA (1) | CA2250712C (es) |
CZ (1) | CZ294613B6 (es) |
DE (2) | DE904095T1 (es) |
EA (1) | EA001622B1 (es) |
ES (1) | ES2132046T3 (es) |
GR (1) | GR990300025T1 (es) |
HK (1) | HK1017275A1 (es) |
ID (1) | ID19769A (es) |
IL (2) | IL126486A0 (es) |
IN (1) | IN186316B (es) |
OA (1) | OA10895A (es) |
PL (1) | PL329404A1 (es) |
PT (1) | PT904095E (es) |
TR (1) | TR199802043T2 (es) |
TW (1) | TW509724B (es) |
WO (1) | WO1997038703A1 (es) |
ZA (1) | ZA973108B (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5824774A (en) * | 1996-04-12 | 1998-10-20 | Board Of Trustees Of The University Of Kentucky | Chimeric isoprenoid synthases and uses thereof |
US7186891B1 (en) * | 1996-04-12 | 2007-03-06 | University Of Kentucky, Research Foundation | Plant cells and plants expressing chimeric isoprenoid synthases |
US8106260B2 (en) * | 1996-04-12 | 2012-01-31 | The Board Of Trustees Of The University Of Kentucky | Chimeric isoprenoid synthases and uses thereof |
US5945726A (en) * | 1996-12-16 | 1999-08-31 | Micron Technology, Inc. | Lateral bipolar transistor |
AR022383A1 (es) | 1998-09-18 | 2002-09-04 | Univ Kentucky Res Found | Sintasas |
US6358712B1 (en) | 1999-01-05 | 2002-03-19 | Trustee Of Boston University | Ordered gene assembly |
US20040005673A1 (en) * | 2001-06-29 | 2004-01-08 | Kevin Jarrell | System for manipulating nucleic acids |
CA2360011A1 (en) * | 1999-01-05 | 2000-07-13 | Trustees Of Boston University | Ordered gene assembly |
AU2001278098A1 (en) | 2000-07-31 | 2002-02-13 | Frederick M. Hahn | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
AU2012202780B2 (en) * | 2001-03-09 | 2014-07-03 | University Of Kentucky Research Foundation | Cytochrome P450s and Uses Thereof |
CA2954889A1 (en) | 2001-03-09 | 2002-09-19 | University Of Kentucky Research Foundation | Cytochrome p450s and uses thereof |
AU2013204829B2 (en) * | 2001-03-09 | 2013-07-04 | University Of Kentucky Research Foundation | Cytochrome P450s and uses thereof |
US7172886B2 (en) * | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
US7192751B2 (en) * | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
US7442785B2 (en) | 2003-07-24 | 2008-10-28 | The University Of Kentucky Research Foundation | Sesquiterpene synthase gene and protein |
US8124811B2 (en) * | 2007-03-20 | 2012-02-28 | Allylix, Inc. | Fragrance and methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one |
DK2162537T3 (da) | 2007-06-01 | 2012-04-23 | Sapphire Energy Inc | Anvendelse af genetisk modificerede organismer til at frembringe biomasse-nedbrydende enzymer. |
CA2698289A1 (en) | 2007-09-11 | 2009-03-19 | Sapphire Energy, Inc. | Methods of producing organic products with photosynthetic organisms and products and compositions thereof |
KR20100082837A (ko) * | 2007-09-11 | 2010-07-20 | 사파이어 에너지, 인크. | 광합성 생물들에 의한 분자 생산 |
MX2010006576A (es) * | 2007-12-13 | 2010-10-15 | Danisco Us Inc | Composiciones y metodos para producir isopreno. |
US8034992B2 (en) * | 2008-06-16 | 2011-10-11 | Academia Sinica | Gibberellin 2-oxidase genes and uses thereof |
WO2010019696A2 (en) | 2008-08-12 | 2010-02-18 | Allylix, Inc. | Method for production of isoprenoids |
JP2013544084A (ja) | 2010-10-29 | 2013-12-12 | アリリクス・インコーポレイテッド | 改変されたバレンセンシンターゼポリペプチド、コーディング核酸分子およびその使用 |
US9550815B2 (en) | 2012-01-23 | 2017-01-24 | University Of British Columbia | ABC terpenoid transporters and methods of using the same |
JP5950253B2 (ja) * | 2012-02-13 | 2016-07-13 | 住友ゴム工業株式会社 | イソプレノイドの製造方法、及びイソプレノイド |
US9353385B2 (en) | 2012-07-30 | 2016-05-31 | Evolva, Inc. | Sclareol and labdenediol diphosphate synthase polypeptides, encoding nucleic acid molecules and uses thereof |
CN105121647A (zh) | 2012-11-01 | 2015-12-02 | 不列颠哥伦比亚大学 | 细胞色素p450和细胞色素p450还原酶多肽、编码核酸分子及其用途 |
EP2970934B1 (en) | 2013-03-14 | 2017-08-16 | Evolva, Inc. | Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof |
CN111621508B (zh) * | 2020-06-11 | 2022-07-01 | 云南中烟工业有限责任公司 | 烟草萜类合成酶NtTPS7基因及其载体与应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE185042T1 (de) * | 1993-04-02 | 1999-10-15 | Pioneer Hi Bred Int | Bekämpfung von diabrotica undecimpunctata mittels limonen |
CA2118071C (en) * | 1993-10-28 | 2004-09-14 | Rodney B. Croteau | Dna encoding limonene synthase from mentha spicata |
US5824774A (en) * | 1996-04-12 | 1998-10-20 | Board Of Trustees Of The University Of Kentucky | Chimeric isoprenoid synthases and uses thereof |
-
1996
- 1996-04-12 US US08/631,341 patent/US5824774A/en not_active Expired - Lifetime
-
1997
- 1997-04-11 AU AU27264/97A patent/AU2726497A/en not_active Abandoned
- 1997-04-11 BR BR9708650A patent/BR9708650A/pt not_active Application Discontinuation
- 1997-04-11 CZ CZ19983179A patent/CZ294613B6/cs not_active IP Right Cessation
- 1997-04-11 EA EA199800917A patent/EA001622B1/ru not_active IP Right Cessation
- 1997-04-11 IL IL12648697A patent/IL126486A0/xx active IP Right Grant
- 1997-04-11 ES ES97921142T patent/ES2132046T3/es not_active Expired - Lifetime
- 1997-04-11 AT AT97921142T patent/ATE223225T1/de not_active IP Right Cessation
- 1997-04-11 WO PCT/US1997/005986 patent/WO1997038703A1/en active IP Right Grant
- 1997-04-11 JP JP9537218A patent/JP2000508899A/ja not_active Withdrawn
- 1997-04-11 PT PT97921142T patent/PT904095E/pt unknown
- 1997-04-11 DE DE0904095T patent/DE904095T1/de active Pending
- 1997-04-11 AP APAP/P/1997/000971A patent/AP808A/en active
- 1997-04-11 TW TW086104693A patent/TW509724B/zh not_active IP Right Cessation
- 1997-04-11 TR TR1998/02043T patent/TR199802043T2/xx unknown
- 1997-04-11 EP EP97921142A patent/EP0904095B1/en not_active Expired - Lifetime
- 1997-04-11 ZA ZA9703108A patent/ZA973108B/xx unknown
- 1997-04-11 PL PL97329404A patent/PL329404A1/xx unknown
- 1997-04-11 IN IN947DE1997 patent/IN186316B/en unknown
- 1997-04-11 CA CA002250712A patent/CA2250712C/en not_active Expired - Lifetime
- 1997-04-11 EP EP02009895A patent/EP1229122A3/en not_active Withdrawn
- 1997-04-11 KR KR1019980708111A patent/KR20000005385A/ko not_active Application Discontinuation
- 1997-04-11 DE DE69715192T patent/DE69715192T2/de not_active Expired - Fee Related
- 1997-04-14 AR ARP970101486A patent/AR006638A1/es not_active Application Discontinuation
- 1997-04-14 ID IDP971219A patent/ID19769A/id unknown
-
1998
- 1998-08-14 US US09/134,699 patent/US6072045A/en not_active Expired - Lifetime
- 1998-10-08 IL IL126486A patent/IL126486A/en not_active IP Right Cessation
- 1998-10-09 OA OA9800191A patent/OA10895A/en unknown
-
1999
- 1999-01-01 GR GR990300025T patent/GR990300025T1/el unknown
- 1999-06-22 HK HK99102647A patent/HK1017275A1/xx not_active IP Right Cessation
-
2011
- 2011-08-30 JP JP2011186897A patent/JP2012005499A/ja active Pending
-
2014
- 2014-12-24 JP JP2014259849A patent/JP2015057074A/ja active Pending
-
2015
- 2015-07-03 JP JP2015134197A patent/JP2015171387A/ja active Pending
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