DE69936049T2 - Monoklonale antikörper spezifisch für die extrazelluläre domäne des prostata-spezifischen membranantigens - Google Patents

Monoklonale antikörper spezifisch für die extrazelluläre domäne des prostata-spezifischen membranantigens Download PDF

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Publication number
DE69936049T2
DE69936049T2 DE69936049T DE69936049T DE69936049T2 DE 69936049 T2 DE69936049 T2 DE 69936049T2 DE 69936049 T DE69936049 T DE 69936049T DE 69936049 T DE69936049 T DE 69936049T DE 69936049 T2 DE69936049 T2 DE 69936049T2
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Germany
Prior art keywords
psma
antibody
cells
antibodies
protein
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE69936049T
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German (de)
English (en)
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DE69936049D1 (de
Inventor
Gerald P. Seattle MURPHY
Alton L. Redmond BOYNTON
Eric H. Bothell HOLMES
William Thomas Redmond TINO
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ER Squibb and Sons LLC
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Medarex LLC
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69936049T 1998-03-18 1999-03-18 Monoklonale antikörper spezifisch für die extrazelluläre domäne des prostata-spezifischen membranantigens Expired - Lifetime DE69936049T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/044,668 US6150508A (en) 1996-03-25 1998-03-18 Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
US44668 1998-03-18
PCT/US1999/005864 WO1999047554A1 (en) 1998-03-18 1999-03-18 Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen

Publications (2)

Publication Number Publication Date
DE69936049D1 DE69936049D1 (de) 2007-06-21
DE69936049T2 true DE69936049T2 (de) 2008-01-10

Family

ID=21933651

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69936049T Expired - Lifetime DE69936049T2 (de) 1998-03-18 1999-03-18 Monoklonale antikörper spezifisch für die extrazelluläre domäne des prostata-spezifischen membranantigens

Country Status (13)

Country Link
US (1) US6150508A (enExample)
EP (2) EP1854808A3 (enExample)
JP (1) JP4229591B2 (enExample)
AT (1) ATE361935T1 (enExample)
AU (1) AU768558B2 (enExample)
CA (1) CA2323096C (enExample)
CY (1) CY1106790T1 (enExample)
DE (1) DE69936049T2 (enExample)
DK (1) DK1064303T3 (enExample)
ES (1) ES2288017T3 (enExample)
IL (2) IL138497A0 (enExample)
PT (1) PT1064303E (enExample)
WO (1) WO1999047554A1 (enExample)

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US6953668B1 (en) 1992-11-05 2005-10-11 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen
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US20030180290A1 (en) * 1995-06-07 2003-09-25 Idec Pharmaceuticals Corporation Anti-CD80 antibody having ADCC activity for ADCC mediated killing of B cell lymphoma cells alone or in combination with other therapies
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Also Published As

Publication number Publication date
EP1064303A4 (en) 2005-03-02
DE69936049D1 (de) 2007-06-21
JP2002506629A (ja) 2002-03-05
ATE361935T1 (de) 2007-06-15
AU768558B2 (en) 2003-12-18
IL138497A (en) 2007-07-04
ES2288017T3 (es) 2007-12-16
CA2323096A1 (en) 1999-09-23
AU3189699A (en) 1999-10-11
EP1854808A2 (en) 2007-11-14
EP1854808A3 (en) 2008-02-27
US6150508A (en) 2000-11-21
IL138497A0 (en) 2001-10-31
JP4229591B2 (ja) 2009-02-25
CA2323096C (en) 2004-10-19
WO1999047554A1 (en) 1999-09-23
DK1064303T3 (da) 2007-09-17
CY1106790T1 (el) 2012-05-23
EP1064303A1 (en) 2001-01-03
PT1064303E (pt) 2007-08-21
EP1064303B1 (en) 2007-05-09

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