PT1064303E - Anticorpo monoclonal específico para o domínio extracelular do antigénio de membrana específico da prostata - Google Patents
Anticorpo monoclonal específico para o domínio extracelular do antigénio de membrana específico da prostata Download PDFInfo
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/044,668 US6150508A (en) | 1996-03-25 | 1998-03-18 | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1064303E true PT1064303E (pt) | 2007-08-21 |
Family
ID=21933651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99913932T PT1064303E (pt) | 1998-03-18 | 1999-03-18 | Anticorpo monoclonal específico para o domínio extracelular do antigénio de membrana específico da prostata |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6150508A (enExample) |
| EP (2) | EP1064303B1 (enExample) |
| JP (1) | JP4229591B2 (enExample) |
| AT (1) | ATE361935T1 (enExample) |
| AU (1) | AU768558B2 (enExample) |
| CA (1) | CA2323096C (enExample) |
| CY (1) | CY1106790T1 (enExample) |
| DE (1) | DE69936049T2 (enExample) |
| DK (1) | DK1064303T3 (enExample) |
| ES (1) | ES2288017T3 (enExample) |
| IL (2) | IL138497A0 (enExample) |
| PT (1) | PT1064303E (enExample) |
| WO (1) | WO1999047554A1 (enExample) |
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| US5965132A (en) | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| US6749853B1 (en) | 1992-03-05 | 2004-06-15 | Board Of Regents, The University Of Texas System | Combined methods and compositions for coagulation and tumor treatment |
| US7105159B1 (en) | 1992-11-05 | 2006-09-12 | Sloan-Kettering Institute For Cancer Research | Antibodies to prostate-specific membrane antigen |
| US6953668B1 (en) | 1992-11-05 | 2005-10-11 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
| US7070782B1 (en) * | 1992-11-05 | 2006-07-04 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
| US6569432B1 (en) * | 1995-02-24 | 2003-05-27 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
| US7037647B1 (en) | 1995-02-24 | 2006-05-02 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen and uses thereof |
| US20030180290A1 (en) * | 1995-06-07 | 2003-09-25 | Idec Pharmaceuticals Corporation | Anti-CD80 antibody having ADCC activity for ADCC mediated killing of B cell lymphoma cells alone or in combination with other therapies |
| US20040253246A1 (en) * | 1996-02-23 | 2004-12-16 | Israeli Ron S. | Prostate-specific membrane antigen and uses thereof |
| US6962981B1 (en) * | 1996-03-25 | 2005-11-08 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
| US7381407B1 (en) | 1996-03-25 | 2008-06-03 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
| US6136311A (en) * | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
| US6107090A (en) | 1996-05-06 | 2000-08-22 | Cornell Research Foundation, Inc. | Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains |
| EP1710256A1 (en) * | 1999-07-29 | 2006-10-11 | Medarex, Inc. | Human monoclonal antibodies to prostate specific membrane antigen |
| ATE342282T1 (de) * | 1999-07-29 | 2006-11-15 | Medarex Inc | Humane monoklonale antikörper gegen prostata spezifisches membranantigen |
| US6379550B1 (en) * | 2000-07-24 | 2002-04-30 | Health Research, Inc. | Method for detecting PSA and its molecular forms using thiophilic gel |
| US6892140B1 (en) * | 2000-11-27 | 2005-05-10 | Enteron, Inc. | Immunogenic cancer peptides and uses thereof |
| US20020132983A1 (en) * | 2000-11-30 | 2002-09-19 | Junghans Richard P. | Antibodies as chimeric effector cell receptors against tumor antigens |
| JP4463475B2 (ja) * | 2001-01-31 | 2010-05-19 | バイオジェン アイデック インコーポレイテッド | 腫瘍疾患の治療における免疫調節性抗体の使用 |
| US20030103971A1 (en) * | 2001-11-09 | 2003-06-05 | Kandasamy Hariharan | Immunoregulatory antibodies and uses thereof |
| WO2003008537A2 (en) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
| WO2002096460A1 (en) * | 2001-05-30 | 2002-12-05 | Cornell Research Foundation, Inc. | Endopeptidase/anti-psma antibody fusion proteins for treatment of cancer |
| US7666414B2 (en) * | 2001-06-01 | 2010-02-23 | Cornell Research Foundation, Inc. | Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen |
| US7514078B2 (en) * | 2001-06-01 | 2009-04-07 | Cornell Research Foundation, Inc. | Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies |
| JP4619651B2 (ja) * | 2001-06-01 | 2011-01-26 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 前立腺特異的膜抗原に対する修飾抗体およびその使用 |
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| AU2002305767B2 (en) * | 2001-09-20 | 2008-04-10 | Cornell Research Foundation, Inc. | Methods and compositions for treating and preventing skin disorders using binding agents specific for PSMA |
| WO2003028840A2 (en) * | 2001-09-27 | 2003-04-10 | Board Of Regents, The University Of Texas System | Combined compositions and methods for tumor vasculature coagulation and treatment |
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| US20070031438A1 (en) * | 2001-12-10 | 2007-02-08 | Junghans Richard P | Antibodies as chimeric effector cell receptors against tumor antigens |
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| KR20110025885A (ko) | 2002-07-15 | 2011-03-11 | 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 포스파티딜에탄올아민에 결합하는 펩타이드, 및 바이러스 감염을 치료하는데 있어서 이의 용도 |
| AU2002364501A1 (en) * | 2002-08-30 | 2004-03-19 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
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| DE60323677D1 (de) * | 2003-01-10 | 2008-10-30 | Millennium Pharm Inc | Verfahren zur bestimmung des wiederauftretens von prostata krebs |
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| WO2005100404A1 (en) * | 2004-04-19 | 2005-10-27 | Proscan Rx Pharma | Prostate cancer diagnosis and treatment |
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| US20090226367A1 (en) * | 2005-03-11 | 2009-09-10 | Euro-Celtique S.A. | Compositions comprising an anti-ca125 antibody and a cytotoxic compound and their use for the treatment of cancer |
| CN101141955A (zh) * | 2005-04-08 | 2008-03-12 | 内尔维阿诺医学科学有限公司 | 包含被取代的丙烯酰基偏端霉素衍生物以及抑制生长因子或其受体的抗体的抗肿瘤组合 |
| LT5414B (lt) * | 2005-04-13 | 2007-04-25 | Biotechnologijos Institutas | Monokloninių antikūnų gavimo būdas, hibridomos, gautos šiuo būdu ir rekombinantinės chimerinės į virusus panašios dalelės su įterptais kitų baltymų fragmentais kaip imunogenai hibridomų gavimui šiuo būdu |
| US7718775B2 (en) * | 2005-04-14 | 2010-05-18 | Scinopharm Taiwan, Ltd. | Monoclonal antibody with the capability of neutralizing enterovirus type 71 infection |
| EP1726650A1 (en) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
| WO2007109321A2 (en) | 2006-03-20 | 2007-09-27 | The Regents Of The University Of California | Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting |
| BE1017200A3 (nl) * | 2006-07-03 | 2008-04-01 | Tekni Plex Europ Nv | Filmstructuur met hoge zuurstofbarriere eigenschappen en werkwijze voor het vervaardigen van zulke filmstructuur. |
| EP2162152A2 (en) * | 2007-06-01 | 2010-03-17 | Biogen Idec MA, Inc. | Cripto binding molecules |
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| HUE045435T2 (hu) | 2012-10-12 | 2019-12-30 | Medimmune Ltd | Pirrolobenzodiazepinek és konjugátumaik |
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| SG10201908685QA (en) | 2015-06-22 | 2019-10-30 | Bayer Pharma AG | Antibody drug conjugates (adcs) and antibody prodrug conjugates (apdcs) with enzymatically cleavable groups |
| JOP20160154B1 (ar) * | 2015-07-31 | 2021-08-17 | Regeneron Pharma | أجسام ضادة مضاد لل psma، وجزيئات رابطة لمستضد ثنائي النوعية الذي يربط psma و cd3، واستخداماتها |
| ES3020458T3 (en) | 2015-08-07 | 2025-05-22 | Imaginab Inc | Antigen binding constructs to target molecules |
| WO2017053469A2 (en) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| WO2017060322A2 (en) | 2015-10-10 | 2017-04-13 | Bayer Pharma Aktiengesellschaft | Ptefb-inhibitor-adc |
| CN105524169A (zh) * | 2016-02-03 | 2016-04-27 | 南昌大学 | 一种能特异结合前列腺特异性膜抗原的单域重链抗体 |
| CN105524170A (zh) * | 2016-02-03 | 2016-04-27 | 南昌大学 | 能特异结合前列腺特异性膜抗原的纳米抗体 |
| CN105542007A (zh) * | 2016-02-03 | 2016-05-04 | 南昌大学 | 一种能特异结合前列腺特异性膜抗原胞外区的单域重链抗体 |
| AU2017236431A1 (en) | 2016-03-24 | 2018-09-27 | Bayer Pharma Aktiengesellschaft | Prodrugs of cytotoxic active agents having enzymatically cleavable groups |
| CA3027445A1 (en) | 2016-06-15 | 2017-12-21 | Bayer Pharma Aktiengesellschaft | Specific antibody-drug-conjugates (adcs) with ksp inhibitors and anti-cd123-antibodies |
| JP2019534882A (ja) | 2016-10-11 | 2019-12-05 | メドイミューン・リミテッドMedImmune Limited | 免疫介在性療法薬を有する抗体−薬物コンジュゲート |
| WO2018114804A1 (de) | 2016-12-21 | 2018-06-28 | Bayer Pharma Aktiengesellschaft | Spezifische antikörper-wirkstoff-konjugate (adcs) mit ksp-inhibitoren |
| MX2019007641A (es) | 2016-12-21 | 2019-09-09 | Bayer Pharma AG | Conjugados de ligando-farmaco (adcs) con grupos escindibles enzimaticamente. |
| EP3558386A1 (de) | 2016-12-21 | 2019-10-30 | Bayer Aktiengesellschaft | Prodrugs von cytotoxischen wirkstoffen mit enzymatisch spaltbaren gruppen |
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| WO2022079211A1 (en) | 2020-10-16 | 2022-04-21 | Adc Therapeutics Sa | Glycoconjugates |
| GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
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Family Cites Families (6)
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|---|---|---|---|---|
| US5162504A (en) * | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
| US5489525A (en) * | 1992-10-08 | 1996-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibodies to prostate cells |
| EP1757694A3 (en) * | 1992-11-05 | 2008-02-27 | Sloan Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
| US5773292A (en) * | 1995-06-05 | 1998-06-30 | Cornell University | Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood |
| IL126314A (en) * | 1996-03-25 | 2003-07-31 | Northwest Biotherapeutics Inc | Monoclonal antibodies having an antigen binding region specific for the extracellular domain of prostate specific membrane antigen (psma) |
| US6107090A (en) * | 1996-05-06 | 2000-08-22 | Cornell Research Foundation, Inc. | Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains |
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1998
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1999
- 1999-03-18 PT PT99913932T patent/PT1064303E/pt unknown
- 1999-03-18 AT AT99913932T patent/ATE361935T1/de active
- 1999-03-18 EP EP99913932A patent/EP1064303B1/en not_active Expired - Lifetime
- 1999-03-18 IL IL13849799A patent/IL138497A0/xx active IP Right Grant
- 1999-03-18 JP JP2000536745A patent/JP4229591B2/ja not_active Expired - Lifetime
- 1999-03-18 DE DE69936049T patent/DE69936049T2/de not_active Expired - Lifetime
- 1999-03-18 ES ES99913932T patent/ES2288017T3/es not_active Expired - Lifetime
- 1999-03-18 EP EP07009216A patent/EP1854808A3/en not_active Withdrawn
- 1999-03-18 AU AU31896/99A patent/AU768558B2/en not_active Expired
- 1999-03-18 DK DK99913932T patent/DK1064303T3/da active
- 1999-03-18 WO PCT/US1999/005864 patent/WO1999047554A1/en not_active Ceased
- 1999-03-18 CA CA002323096A patent/CA2323096C/en not_active Expired - Lifetime
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2000
- 2000-09-15 IL IL138497A patent/IL138497A/en not_active IP Right Cessation
-
2007
- 2007-08-06 CY CY20071101042T patent/CY1106790T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL138497A0 (en) | 2001-10-31 |
| DE69936049T2 (de) | 2008-01-10 |
| WO1999047554A1 (en) | 1999-09-23 |
| ES2288017T3 (es) | 2007-12-16 |
| CA2323096A1 (en) | 1999-09-23 |
| EP1854808A2 (en) | 2007-11-14 |
| AU3189699A (en) | 1999-10-11 |
| IL138497A (en) | 2007-07-04 |
| JP4229591B2 (ja) | 2009-02-25 |
| EP1064303B1 (en) | 2007-05-09 |
| JP2002506629A (ja) | 2002-03-05 |
| CA2323096C (en) | 2004-10-19 |
| DE69936049D1 (de) | 2007-06-21 |
| EP1064303A1 (en) | 2001-01-03 |
| AU768558B2 (en) | 2003-12-18 |
| ATE361935T1 (de) | 2007-06-15 |
| EP1064303A4 (en) | 2005-03-02 |
| EP1854808A3 (en) | 2008-02-27 |
| CY1106790T1 (el) | 2012-05-23 |
| DK1064303T3 (da) | 2007-09-17 |
| US6150508A (en) | 2000-11-21 |
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