DE69929240T2 - Impfstoffe mit erhöhter wirkung basierend auf chimären immunoglobulin e peptiden - Google Patents

Impfstoffe mit erhöhter wirkung basierend auf chimären immunoglobulin e peptiden Download PDF

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Publication number
DE69929240T2
DE69929240T2 DE69929240T DE69929240T DE69929240T2 DE 69929240 T2 DE69929240 T2 DE 69929240T2 DE 69929240 T DE69929240 T DE 69929240T DE 69929240 T DE69929240 T DE 69929240T DE 69929240 T2 DE69929240 T2 DE 69929240T2
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DE
Germany
Prior art keywords
ige
mammal
nucleic acid
domain
immunogenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69929240T
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German (de)
English (en)
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DE69929240D1 (de
Inventor
T. Lars HELLMAN
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Resistentia Pharmaceuticals AB
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Resistentia Pharmaceuticals AB
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Publication of DE69929240D1 publication Critical patent/DE69929240D1/de
Application granted granted Critical
Publication of DE69929240T2 publication Critical patent/DE69929240T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69929240T 1998-11-02 1999-10-21 Impfstoffe mit erhöhter wirkung basierend auf chimären immunoglobulin e peptiden Expired - Lifetime DE69929240T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10665298P 1998-11-02 1998-11-02
US106652P 1998-11-02
US401636 1999-09-22
US09/401,636 US6913749B2 (en) 1998-11-02 1999-09-22 Immunogenic polypeptides for inducing anti-self IgE responses
PCT/SE1999/001896 WO2000025722A2 (en) 1998-11-02 1999-10-21 ENHANCED VACCINES COMPRISING SELF AND NON-SELF IgE PORTIONS OR DIMERIC ANTIGENS

Publications (2)

Publication Number Publication Date
DE69929240D1 DE69929240D1 (de) 2006-02-02
DE69929240T2 true DE69929240T2 (de) 2006-08-31

Family

ID=26803871

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69929240T Expired - Lifetime DE69929240T2 (de) 1998-11-02 1999-10-21 Impfstoffe mit erhöhter wirkung basierend auf chimären immunoglobulin e peptiden

Country Status (17)

Country Link
US (3) US6913749B2 (enExample)
EP (1) EP1135158B1 (enExample)
JP (2) JP4205861B2 (enExample)
KR (1) KR100559918B1 (enExample)
AT (1) ATE314087T1 (enExample)
AU (1) AU771889B2 (enExample)
CA (1) CA2348756A1 (enExample)
DE (1) DE69929240T2 (enExample)
DK (1) DK1135158T3 (enExample)
ES (1) ES2255325T3 (enExample)
HU (1) HUP0105392A3 (enExample)
IL (1) IL142582A0 (enExample)
NO (1) NO20012135L (enExample)
NZ (1) NZ511079A (enExample)
PL (1) PL348611A1 (enExample)
PT (1) PT1135158E (enExample)
WO (1) WO2000025722A2 (enExample)

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CA2698079C (en) 2001-02-20 2015-01-13 Ortho-Mcneil Pharmaceutical, Inc. A cell therapy method for the treatment of tumors
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ES2329453T3 (es) * 2001-05-15 2009-11-26 Ortho Mcneil Janssen Pharm Cebado ex-vivo para generar linfocitos t citotoxicos especificos del ligando cd40 para tratar enfermedades autoinmunitarias y alergicas.
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CA2486464A1 (en) * 2002-05-21 2003-11-27 Resistentia Pharmaceuticals Ab Chimeric ige polypeptides and host cells
CA2497660A1 (en) * 2002-09-05 2004-03-18 Resistentia Pharmaceuticals Ab Allergy vaccines
US20080118524A1 (en) * 2006-10-20 2008-05-22 Stefan Persson Anti-IgE Vaccines
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WO2009142772A2 (en) * 2008-05-23 2009-11-26 Mastcell Pharmaceuticals, Inc. Methods and treatment for allergies and inflammation associated with gastrointestinal diseases
WO2010067286A2 (en) 2008-12-09 2010-06-17 Pfizer Vaccines Llc IgE CH3 PEPTIDE VACCINE
EP2942061A3 (en) 2010-06-07 2016-01-13 Pfizer Vaccines LLC Ige ch3 peptide vaccine
US9187553B2 (en) * 2012-01-25 2015-11-17 Swey-Shen Chen Displaying native human IgE neutralizing FcepsilonRIa-contacting IgE B-cell epitopes by constraining super beta(b)-strands and cystine knots on thermostable protein scaffold
WO2013156054A1 (en) 2012-04-16 2013-10-24 Universität Stuttgart The igm and ige heavy chain domain 2 as covalently linked homodimerization modules for the generation of fusion proteins with dual specificity
EP2862873B1 (en) 2012-06-18 2020-04-29 Nippon Zenyaku Kogyo Co., Ltd. IgE PEPTIDE VACCINE
SG11201806427WA (en) 2016-02-16 2018-08-30 Regeneron Pharma Non-human animals having a mutant kynureninase gene
EP4582442A3 (en) 2019-06-24 2025-10-29 Universität Stuttgart Tnfr2 agonists with improved stability

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Also Published As

Publication number Publication date
JP2002531064A (ja) 2002-09-24
JP4188353B2 (ja) 2008-11-26
ATE314087T1 (de) 2006-01-15
US7459158B2 (en) 2008-12-02
JP4205861B2 (ja) 2009-01-07
IL142582A0 (en) 2002-03-10
HUP0105392A2 (hu) 2002-04-29
DE69929240D1 (de) 2006-02-02
KR100559918B1 (ko) 2006-03-13
HUP0105392A3 (en) 2008-04-28
PL348611A1 (en) 2002-06-03
AU2008100A (en) 2000-05-22
KR20010089364A (ko) 2001-10-06
NZ511079A (en) 2003-08-29
WO2000025722A2 (en) 2000-05-11
US20030031663A1 (en) 2003-02-13
EP1135158B1 (en) 2005-12-28
HK1042844A1 (en) 2002-08-30
ES2255325T3 (es) 2006-06-16
WO2000025722A3 (en) 2000-10-12
NO20012135D0 (no) 2001-04-30
US6913749B2 (en) 2005-07-05
CA2348756A1 (en) 2000-05-11
PT1135158E (pt) 2006-05-31
DK1135158T3 (da) 2006-05-15
EP1135158A2 (en) 2001-09-26
NO20012135L (no) 2001-06-25
US20010038843A1 (en) 2001-11-08
AU771889B2 (en) 2004-04-08
US20040076625A1 (en) 2004-04-22
JP2006068015A (ja) 2006-03-16

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Representative=s name: MEISSNER, BOLTE & PARTNER GBR, 80538 MUENCHEN