DE69926377D1 - Orale flüssige mucoadhäsive zusammensetzungen - Google Patents

Orale flüssige mucoadhäsive zusammensetzungen

Info

Publication number
DE69926377D1
DE69926377D1 DE69926377T DE69926377T DE69926377D1 DE 69926377 D1 DE69926377 D1 DE 69926377D1 DE 69926377 T DE69926377 T DE 69926377T DE 69926377 T DE69926377 T DE 69926377T DE 69926377 D1 DE69926377 D1 DE 69926377D1
Authority
DE
Germany
Prior art keywords
composition
safe
mixtures
effective amount
respiratory tract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69926377T
Other languages
English (en)
Other versions
DE69926377T2 (de
Inventor
Joseph Dobrozsi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of DE69926377D1 publication Critical patent/DE69926377D1/de
Application granted granted Critical
Publication of DE69926377T2 publication Critical patent/DE69926377T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69926377T 1998-08-24 1999-08-24 Orale flüssige mucoadhäsive zusammensetzungen Expired - Lifetime DE69926377T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9757898P 1998-08-24 1998-08-24
US97578P 1998-08-24
PCT/US1999/019202 WO2000010529A1 (en) 1998-08-24 1999-08-24 Oral liquid mucoadhesive compositions

Publications (2)

Publication Number Publication Date
DE69926377D1 true DE69926377D1 (de) 2005-09-01
DE69926377T2 DE69926377T2 (de) 2006-06-01

Family

ID=22264129

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69926377T Expired - Lifetime DE69926377T2 (de) 1998-08-24 1999-08-24 Orale flüssige mucoadhäsive zusammensetzungen

Country Status (17)

Country Link
US (1) US6319513B1 (de)
EP (1) EP1107733B1 (de)
JP (1) JP2002523354A (de)
KR (1) KR100413877B1 (de)
CN (1) CN1195494C (de)
AT (1) ATE300282T1 (de)
AU (1) AU761968B2 (de)
BR (1) BR9913178B1 (de)
CA (1) CA2338704C (de)
CO (1) CO5140082A1 (de)
DE (1) DE69926377T2 (de)
HU (1) HUP0103388A3 (de)
ID (1) ID29576A (de)
NO (1) NO20010832D0 (de)
PE (1) PE20000862A1 (de)
TR (1) TR200100628T2 (de)
WO (1) WO2000010529A1 (de)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223416B2 (en) * 1999-06-28 2007-05-29 Minu, L.L.C. Topical composition
US6843981B1 (en) * 1999-07-02 2005-01-18 Mitsubishi Gas Chemical Company, Inc. Tooth bleaching compositions and methods of bleaching discolored tooth
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
DE60117043T2 (de) * 2000-11-22 2006-07-13 Rxkinetix, Inc., Louisville Behandlung von mukositis
US7927600B2 (en) * 2001-03-30 2011-04-19 Emile Loria Anti-allergic pharmaceutical composition containing at least one allergen and at least one antihistamine compound
FR2822709B1 (fr) * 2001-03-30 2007-01-19 Antialis Composition pharmaceutique anti-allergique comprenant au moins un allergene et au moins un compose antihistaminique
US7179476B2 (en) * 2001-08-09 2007-02-20 Sekisui Chemical Co., Ltd. Medical composition for external use for dermatosis
CN1764432A (zh) * 2001-08-24 2006-04-26 明太古公司 用于治疗或预防细菌感染和真茵感染的漱口剂
US20080182841A1 (en) * 2001-10-29 2008-07-31 Levine Howard L Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US8425892B2 (en) * 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
PL211494B1 (pl) * 2001-12-21 2012-05-31 Alcon Zastosowanie syntetycznych, nieorganicznych nanocząstek jako nośników dla leków i kompozycja farmaceutyczna do oczu lub uszu
US20050038039A1 (en) * 2002-01-15 2005-02-17 Domenico Fanara Formulations
BG65734B1 (bg) * 2002-02-22 2009-09-30 Био Терапютикс - Еоод Течен мукоадхезивен фармацевтичен състав
US20030166732A1 (en) * 2002-02-27 2003-09-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity
CA2480403A1 (en) * 2002-04-08 2003-10-23 Lavipharm Laboratories Inc. Drug-complex microparticles and methods of making/using same
ES2314227T7 (es) * 2002-04-09 2012-11-19 Flamel Technologies Formulacion farmaceutica oral en forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de amoxilicina.
US6919348B2 (en) * 2002-05-02 2005-07-19 Edward T. Wei Therapeutic 1,2,3,6-tetrahydropyrimidine-2-one compositions and methods therewith
WO2003094968A2 (en) * 2002-05-07 2003-11-20 Altana Pharma Ag Combination of a proton pump inhibitor and a respiratory agent for the treatment of respiratory diseases
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
CN100341498C (zh) 2003-01-21 2007-10-10 千寿制药株式会社 含有2－氨基－3－(4－溴苯甲酰基)苯乙酸的水成液制剂
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US7459146B2 (en) * 2003-05-30 2008-12-02 3M Innovative Properties Company Stabilized aerosol dispersions
US20040242729A1 (en) * 2003-05-30 2004-12-02 3M Innovative Properties Company Stabilized particle dispersions containing surface-modified inorganic nanoparticles
US7109247B2 (en) * 2003-05-30 2006-09-19 3M Innovative Properties Company Stabilized particle dispersions containing nanoparticles
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20050031700A1 (en) * 2003-07-18 2005-02-10 Sanatarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US20050154343A1 (en) * 2004-01-14 2005-07-14 Mohinder Singh Soft tip applicator for relieving mouth pain
US20050266031A1 (en) * 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US7482378B2 (en) * 2004-05-28 2009-01-27 Millenium Specialty Chemicals, Inc. Physiological cooling compositions
WO2006020190A1 (en) * 2004-07-16 2006-02-23 Richard Plymale Dentifrice composition
US20060046998A1 (en) * 2004-08-25 2006-03-02 Fairfield Clinical Trials, Llc Method of treatment of gastroesophageal reflux disease and laryngopharyngeal reflux disease
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
EP2486942B1 (de) 2004-11-24 2018-10-10 Meda Pharmaceuticals Inc. Zusammensetzungen mit azelastin und anwendungsverfahren
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US20060210482A1 (en) * 2005-03-18 2006-09-21 John Cassara Chemical composition and method for cold and sinus relief
US7985743B1 (en) * 2005-07-22 2011-07-26 Gene A. Tabish Topical pain reliever and method of making the same
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
PT1965787E (pt) * 2005-11-30 2013-07-05 Endo Pharmaceuticals Inc Tratamento de xerostomia com um antioxidante que contém enxofre
DOP2006000274A (es) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc Formulación de suspensión de fexofenadina
EP2037916A4 (de) * 2006-04-07 2011-09-14 Mike Nicolaou Reine tritoqualin-isomere
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
WO2008100539A1 (en) * 2007-02-12 2008-08-21 Michalis Nicolaou Treatment of copd, gastro-esophageal reflux disease (gerd), food allergies and other gastrointestinal conditions and disorders ameliorated by proper histamine management using a combination of histidine decarboxylase inhibitors, lra drugs, anti-h1 and/or anti-h2 drugs
WO2008109018A1 (en) * 2007-03-02 2008-09-12 Meda Pharmaceuticals Inc. Compositions comprising carisoprodol and methods of use thereof
EP2002733B1 (de) * 2007-06-08 2016-11-02 The Procter and Gamble Company Natürliche honighaltige Zusammensetzungen und Herstellungsverfahren dafür
AU2014201068B2 (en) * 2007-06-08 2016-07-07 The Procter & Gamble Company Natural honey-containing compositions and method of preparation
ITMI20071623A1 (it) * 2007-08-03 2009-02-04 Vetagro S R L Composizione sinergica comprendente sostanze aromatizzanti ed acidi organici, e relativo uso
WO2009064458A2 (en) 2007-11-13 2009-05-22 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
RU2499592C2 (ru) 2008-04-21 2013-11-27 Отономи, Инк. Фармацевтическая композиция для лечения ушных заболеваний
GB0807621D0 (en) * 2008-04-25 2008-06-04 Ineos Healthcare Ltd Use
JP5421366B2 (ja) 2008-07-21 2014-02-19 オトノミ―，インク． 制御放出性の耳の構造体調節および生来の免疫システム調節化合物および耳の障害の処置のための方法
US8784870B2 (en) * 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
US7914828B2 (en) * 2008-10-17 2011-03-29 Levine Brian M Combination herbal product to benefit respiratory tract
GB2477590A (en) * 2010-02-05 2011-08-10 Biocopea Ltd A non-steroidal anti-inflammatory drug (NSAID) formulation comprising a lipid carrier
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US8895537B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating cardiovascular diseases
US9737500B2 (en) 2010-10-29 2017-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US8361519B2 (en) 2010-11-18 2013-01-29 Aadvantics Pharmaceuticals, Inc. Combination herbal product to benefit respiratory tract in people exposed to smoke
US20140213644A1 (en) * 2010-12-30 2014-07-31 Ziv Harish Formulations and Methods for Prevention and Treatment of Oral Allergy Syndrome
WO2014087419A1 (en) * 2012-12-06 2014-06-12 Colgate-Palmolive Company Oral gel for sensitivity and tooth pain
EP3061501A1 (de) 2015-02-27 2016-08-31 Rottapharm Ltd. Zusammensetzung zur behandlung von akne
EP3117825A1 (de) 2015-07-16 2017-01-18 Rottapharm S.p.A. Orale formulierung mit berberin und morus-alba-extrakt
JP7023461B2 (ja) 2015-07-28 2022-02-22 オトノミ―，インク． 耳の疾病の処置のためのｔｒｋｂ又はｔｒｋｃアゴニスト組成物及び方法
CA3009072A1 (en) 2015-12-30 2017-07-06 Colgate-Palmolive Company Mucin coated silica for bacterial aggregation
KR20190024983A (ko) 2016-06-29 2019-03-08 오토노미, 인코포레이티드 트리글리세라이드 귀 제제 및 이의 용도
US10583081B1 (en) * 2017-11-27 2020-03-10 Richard A. Myers Apparatus and formulation for treating mouth ulcers
WO2019154895A1 (en) 2018-02-08 2019-08-15 Strekin Ag Gel formulation for preventing or treating hearing loss
WO2020009812A1 (en) * 2018-07-02 2020-01-09 Bayer Healthcare Llc Stable pharmaceutical formulations of oxymetazoline
HRP20211996T1 (hr) 2018-09-11 2022-04-01 Lead Biotherapeutics Ltd. Sustav mukoadhezivne disperzijske nanočestice i metoda proizvodnje istog
WO2020168289A1 (en) * 2019-02-15 2020-08-20 Ferrer Medical Innovations, LLC Nasal spray compositions and related treatment methods

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3352752A (en) 1963-07-25 1967-11-14 Tintex Corp Intestinal adsorbent compositions
JPS589083B2 (ja) 1975-05-30 1983-02-18 武田薬品工業株式会社 シヨウリユウザイノセイゾウホウ
FR2346017A1 (fr) 1975-10-23 1977-10-28 Rech Applic Scient Composition therapeutique pour le traitement des affections du tractus gastro-intestinal
FR2502956A1 (fr) * 1981-04-01 1982-10-08 Human Pharm Sa Laboratoires Composition therapeutique utile comme topique digestif
US4427681A (en) 1982-09-16 1984-01-24 Richardson-Vicks, Inc. Thixotropic compositions easily convertible to pourable liquids
JPS61106509A (ja) * 1984-10-29 1986-05-24 Fujisawa Pharmaceut Co Ltd 鼻腔用医薬組成物
AU594765B2 (en) 1986-05-16 1990-03-15 Chugai Seiyaku Kabushiki Kaisha Sucralfate preparations for applications on esophagus mucosa
US5464828A (en) 1988-03-02 1995-11-07 Chugai Pharmaceutical Co., Ltd. Aqueous suspension of sucralfate
US5719197A (en) 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5047244A (en) 1988-06-03 1991-09-10 Watson Laboratories, Inc. Mucoadhesive carrier for delivery of therapeutical agent
EP0452334A4 (en) 1989-10-31 1991-12-11 Watson Laboratoires, Inc. Mucoadhesive carrier for delivery of therapeutical agent
JPH0639368B2 (ja) 1990-02-28 1994-05-25 株式会社萩原技研 シリカゲルを母体とした抗菌性組生物
GB9025710D0 (en) 1990-11-27 1991-01-09 Beecham Group Plc Novel treatment
US5352681A (en) 1991-06-07 1994-10-04 Byk Nederland Bv Pharmaceutical enema preparation
IT1251153B (it) 1991-08-06 1995-05-04 Vectorpharma Int Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica
JPH0725769A (ja) * 1992-10-20 1995-01-27 Fuji Chem Ind Co Ltd アロプリノール医薬用液剤ならびにその製造法
FR2710265B1 (fr) 1993-09-22 1995-10-20 Adir Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs.
US5458879A (en) 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
US5554379A (en) 1994-06-20 1996-09-10 Kv Pharmaceutical Company Long acting GI and esophageal protectant
US5670163A (en) 1994-06-20 1997-09-23 Kv Pharmaceuticals Company Long acting GI and esophageal protectant
US5554380A (en) 1994-08-04 1996-09-10 Kv Pharmaceutical Company Bioadhesive pharmaceutical delivery system
US5466440A (en) 1994-12-30 1995-11-14 Eastman Kodak Company Formulations of oral gastrointestinal diagnostic X-ray contrast agents in combination with pharmaceutically acceptable clays
US5585108A (en) 1994-12-30 1996-12-17 Nanosystems L.L.C. Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
JP3927253B2 (ja) * 1995-02-02 2007-06-06 中外製薬株式会社 スクラルファート製剤
US5580579A (en) 1995-02-15 1996-12-03 Nano Systems L.L.C. Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers
IT1275955B1 (it) * 1995-03-22 1997-10-24 Dompe Spa Formulazioni farmaceutiche in forma di gel tissotropico
FR2739558B1 (fr) 1995-10-05 1997-11-28 Innothera Lab Sa Forme galenique unitaire pour hormonotherapie locale de la secheresse vaginale

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CO5140082A1 (es) 2002-03-22
ATE300282T1 (de) 2005-08-15
KR20010072678A (ko) 2001-07-31
BR9913178B1 (pt) 2014-11-25
BR9913178A (pt) 2001-05-15
US6319513B1 (en) 2001-11-20
AU761968B2 (en) 2003-06-12
ID29576A (id) 2001-09-06
CA2338704A1 (en) 2000-03-02
AU5580999A (en) 2000-03-14
PE20000862A1 (es) 2000-09-13
CN1195494C (zh) 2005-04-06
EP1107733B1 (de) 2005-07-27
NO20010832L (no) 2001-02-19
TR200100628T2 (tr) 2001-10-22
CN1313756A (zh) 2001-09-19
CA2338704C (en) 2004-11-02
HUP0103388A3 (en) 2006-02-28
EP1107733A1 (de) 2001-06-20
JP2002523354A (ja) 2002-07-30
DE69926377T2 (de) 2006-06-01
NO20010832D0 (no) 2001-02-19
KR100413877B1 (ko) 2004-01-07
WO2000010529A1 (en) 2000-03-02
HUP0103388A2 (hu) 2002-01-28

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