CO5140082A1 - Composicion farmaceutica mucoretentiva, liquida acuosa, oral peroral o intranasal que contiene particulas coloidales de dioxido de titanio y metodos para su aplicacion - Google Patents

Composicion farmaceutica mucoretentiva, liquida acuosa, oral peroral o intranasal que contiene particulas coloidales de dioxido de titanio y metodos para su aplicacion

Info

Publication number
CO5140082A1
CO5140082A1 CO99053437A CO99053437A CO5140082A1 CO 5140082 A1 CO5140082 A1 CO 5140082A1 CO 99053437 A CO99053437 A CO 99053437A CO 99053437 A CO99053437 A CO 99053437A CO 5140082 A1 CO5140082 A1 CO 5140082A1
Authority
CO
Colombia
Prior art keywords
agents
peroral
titanium dioxide
pharmaceutical composition
composition
Prior art date
Application number
CO99053437A
Other languages
English (en)
Inventor
Douglas Joseph Dobrozsi
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of CO5140082A1 publication Critical patent/CO5140082A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Photolithography (AREA)

Abstract

La presente invención se relaciona con una composición farmacéutica líquida acuosa mucoretentiva peroral u oral que comprende:(a) de 2% a 50%, aproximadamente, en peso de la composición de partículas coloidales de dióxido de titanio; y(b) una cantidad segura eficaz de un activo farmacéutico que se selecciona del grupo que consiste de agentes gastrointestinales, expectorantes, antitusivos, antihistaminas, broncodilatadores, anestésicos tópicos, agentes para el cuidado bucal, agentes respiratorios misceláneos, y mezclas de estos;en donde la composición tiene una relación de sedimentación a volumen superior a 0,90 aproximadamente cuando se mide después de 48 horas aproximadamente y una relación de viscosidad provocada de por lo menos 1,2 aproximadamente; en donde el agente gastrointestinal se selecciona del grupo que consiste de anticolinérgicos, antagonistas del receptor de H2, laxantes, gastroprotectores, agentes gastrocinéticos y procinéticos, inhibidores de la bomba de protones, antidiarréicos, agentes eficaces para el tratamiento de H.Pylori, agentes polianiónicos, extractos de plantas eficaces para el tratamiento de trastornos gastrointestinales, y mezclas de estos.<EMI FILE="99053437_1" ID="1" IMF=JPEG >
CO99053437A 1998-08-24 1999-08-24 Composicion farmaceutica mucoretentiva, liquida acuosa, oral peroral o intranasal que contiene particulas coloidales de dioxido de titanio y metodos para su aplicacion CO5140082A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9757898P 1998-08-24 1998-08-24

Publications (1)

Publication Number Publication Date
CO5140082A1 true CO5140082A1 (es) 2002-03-22

Family

ID=22264129

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99053437A CO5140082A1 (es) 1998-08-24 1999-08-24 Composicion farmaceutica mucoretentiva, liquida acuosa, oral peroral o intranasal que contiene particulas coloidales de dioxido de titanio y metodos para su aplicacion

Country Status (17)

Country Link
US (1) US6319513B1 (es)
EP (1) EP1107733B1 (es)
JP (1) JP2002523354A (es)
KR (1) KR100413877B1 (es)
CN (1) CN1195494C (es)
AT (1) ATE300282T1 (es)
AU (1) AU761968B2 (es)
BR (1) BR9913178B1 (es)
CA (1) CA2338704C (es)
CO (1) CO5140082A1 (es)
DE (1) DE69926377T2 (es)
HU (1) HUP0103388A3 (es)
ID (1) ID29576A (es)
NO (1) NO20010832L (es)
PE (1) PE20000862A1 (es)
TR (1) TR200100628T2 (es)
WO (1) WO2000010529A1 (es)

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CN1313756A (zh) 2001-09-19
HUP0103388A2 (hu) 2002-01-28
PE20000862A1 (es) 2000-09-13
ID29576A (id) 2001-09-06
CA2338704A1 (en) 2000-03-02
ATE300282T1 (de) 2005-08-15
AU5580999A (en) 2000-03-14
KR100413877B1 (ko) 2004-01-07
CA2338704C (en) 2004-11-02
EP1107733B1 (en) 2005-07-27
DE69926377T2 (de) 2006-06-01
JP2002523354A (ja) 2002-07-30
BR9913178A (pt) 2001-05-15
TR200100628T2 (tr) 2001-10-22
BR9913178B1 (pt) 2014-11-25
WO2000010529A1 (en) 2000-03-02
CN1195494C (zh) 2005-04-06
EP1107733A1 (en) 2001-06-20
US6319513B1 (en) 2001-11-20
AU761968B2 (en) 2003-06-12
KR20010072678A (ko) 2001-07-31
HUP0103388A3 (en) 2006-02-28
NO20010832D0 (no) 2001-02-19
NO20010832L (no) 2001-02-19

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