ATE300282T1 - Orale flüssige mucoadhäsive zusammensetzungen - Google Patents

Orale flüssige mucoadhäsive zusammensetzungen

Info

Publication number
ATE300282T1
ATE300282T1 AT99942429T AT99942429T ATE300282T1 AT E300282 T1 ATE300282 T1 AT E300282T1 AT 99942429 T AT99942429 T AT 99942429T AT 99942429 T AT99942429 T AT 99942429T AT E300282 T1 ATE300282 T1 AT E300282T1
Authority
AT
Austria
Prior art keywords
composition
safe
mixtures
effective amount
respiratory tract
Prior art date
Application number
AT99942429T
Other languages
English (en)
Inventor
Douglas Joseph Dobrozsi
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of ATE300282T1 publication Critical patent/ATE300282T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT99942429T 1998-08-24 1999-08-24 Orale flüssige mucoadhäsive zusammensetzungen ATE300282T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9757898P 1998-08-24 1998-08-24
PCT/US1999/019202 WO2000010529A1 (en) 1998-08-24 1999-08-24 Oral liquid mucoadhesive compositions

Publications (1)

Publication Number Publication Date
ATE300282T1 true ATE300282T1 (de) 2005-08-15

Family

ID=22264129

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99942429T ATE300282T1 (de) 1998-08-24 1999-08-24 Orale flüssige mucoadhäsive zusammensetzungen

Country Status (17)

Country Link
US (1) US6319513B1 (de)
EP (1) EP1107733B1 (de)
JP (1) JP2002523354A (de)
KR (1) KR100413877B1 (de)
CN (1) CN1195494C (de)
AT (1) ATE300282T1 (de)
AU (1) AU761968B2 (de)
BR (1) BR9913178B1 (de)
CA (1) CA2338704C (de)
CO (1) CO5140082A1 (de)
DE (1) DE69926377T2 (de)
HU (1) HUP0103388A3 (de)
ID (1) ID29576A (de)
NO (1) NO20010832D0 (de)
PE (1) PE20000862A1 (de)
TR (1) TR200100628T2 (de)
WO (1) WO2000010529A1 (de)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223416B2 (en) * 1999-06-28 2007-05-29 Minu, L.L.C. Topical composition
WO2001001943A1 (fr) * 1999-07-02 2001-01-11 Mitsubishi Gas Chemical Company, Inc. Compositions pour le blanchiment des dents et methode de blanchiment de dents decolorees
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
MXPA03004546A (es) * 2000-11-22 2003-09-10 Rxkinetix Inc Tratamiento de mucositis.
US7927600B2 (en) * 2001-03-30 2011-04-19 Emile Loria Anti-allergic pharmaceutical composition containing at least one allergen and at least one antihistamine compound
FR2822709B1 (fr) * 2001-03-30 2007-01-19 Antialis Composition pharmaceutique anti-allergique comprenant au moins un allergene et au moins un compose antihistaminique
WO2003013548A1 (en) * 2001-08-09 2003-02-20 Sekisui Chemical Co., Ltd. Medical composition for external use for dermatosis
CN1764432A (zh) * 2001-08-24 2006-04-26 明太古公司 用于治疗或预防细菌感染和真茵感染的漱口剂
US8425892B2 (en) * 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
US20080182841A1 (en) * 2001-10-29 2008-07-31 Levine Howard L Vaginally administered anti-dysrhythmic agents for treating pelvic pain
BR0215238A (pt) 2001-12-21 2005-05-31 Alcon Inc Uso de nanopartìculas inor ânicas sintéticas como veìculos para drogas oftálmicas e óticas
PL212123B1 (pl) * 2002-01-15 2012-08-31 Ucb Farchim Sa Doustna kompozycja farmaceutyczna
BG65734B1 (bg) * 2002-02-22 2009-09-30 Био Терапютикс - Еоод Течен мукоадхезивен фармацевтичен състав
US20030166732A1 (en) * 2002-02-27 2003-09-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity
CA2480403A1 (en) * 2002-04-08 2003-10-23 Lavipharm Laboratories Inc. Drug-complex microparticles and methods of making/using same
KR20050005437A (ko) * 2002-04-09 2005-01-13 플라멜 테크놀로지스 아목시실린의 변형 방출을 위한 마이크로캡슐 수성 현탁액형태의 경구 제약학적 제제
US6919348B2 (en) * 2002-05-02 2005-07-19 Edward T. Wei Therapeutic 1,2,3,6-tetrahydropyrimidine-2-one compositions and methods therewith
RS95204A (sr) * 2002-05-07 2006-12-15 Altana Pharma Ag. Kombinacija za tretman oboljenja disajnih puteva
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
PT1586316E (pt) * 2003-01-21 2008-05-28 Senju Pharma Co Preparação líquida aquosa contendo ácido 2-amino-3-(4- bromobenzoil)fenilacético
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US7459146B2 (en) * 2003-05-30 2008-12-02 3M Innovative Properties Company Stabilized aerosol dispersions
US20040242729A1 (en) * 2003-05-30 2004-12-02 3M Innovative Properties Company Stabilized particle dispersions containing surface-modified inorganic nanoparticles
US7109247B2 (en) 2003-05-30 2006-09-19 3M Innovative Properties Company Stabilized particle dispersions containing nanoparticles
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2005007117A2 (en) * 2003-07-18 2005-01-27 Santarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US20050154343A1 (en) * 2004-01-14 2005-07-14 Mohinder Singh Soft tip applicator for relieving mouth pain
US8815916B2 (en) 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20050266031A1 (en) * 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
US7482378B2 (en) * 2004-05-28 2009-01-27 Millenium Specialty Chemicals, Inc. Physiological cooling compositions
WO2006020190A1 (en) * 2004-07-16 2006-02-23 Richard Plymale Dentifrice composition
WO2006026337A1 (en) * 2004-08-25 2006-03-09 Fairfield Clinical Trials, Llc Combination of a proton pump inhibitor and a h2 antagonist for the treatment of gastroesophageal reflux disease
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
DK2377557T3 (en) 2004-11-24 2017-02-06 Meda Pharmaceuticals Inc Compositions comprising azelastine and methods for its use
US20060210482A1 (en) * 2005-03-18 2006-09-21 John Cassara Chemical composition and method for cold and sinus relief
US7985743B1 (en) * 2005-07-22 2011-07-26 Gene A. Tabish Topical pain reliever and method of making the same
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
WO2007064755A2 (en) * 2005-11-30 2007-06-07 Endo Pharmaceuticals Inc. Treatment of xerostomia with a sulfur-containing antioxidant
DOP2006000274A (es) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc Formulación de suspensión de fexofenadina
US20070238750A1 (en) * 2006-04-07 2007-10-11 Michalis Nicolaou Pure isomers of tritoqualine
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
EP2559434A3 (de) * 2007-02-12 2013-05-29 Mike Nicolaou Behandlung von COPD mit einem Histidine Decarboxylase Inhibitor allein oder kombiniert mit einer anti-H1 Verbindung oder mit einem Leucotriene Rezeptor Antagonist
WO2008109018A1 (en) * 2007-03-02 2008-09-12 Meda Pharmaceuticals Inc. Compositions comprising carisoprodol and methods of use thereof
AU2014201068B2 (en) * 2007-06-08 2016-07-07 The Procter & Gamble Company Natural honey-containing compositions and method of preparation
PL2002733T3 (pl) * 2007-06-08 2017-06-30 The Procter And Gamble Company Kompozycja zawierająca miód naturalny i sposoby jej sporządzania
ITMI20071623A1 (it) 2007-08-03 2009-02-04 Vetagro S R L Composizione sinergica comprendente sostanze aromatizzanti ed acidi organici, e relativo uso
EP2214679B1 (de) 2007-11-13 2019-03-27 Meritage Pharma, Inc. Kortikosteroidzusammensetzungen
KR20130097813A (ko) 2008-04-21 2013-09-03 오토노미, 인코포레이티드 귀 질환 및 병태를 치료하기 위한 귀 조제물
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
GB0807621D0 (en) * 2008-04-25 2008-06-04 Ineos Healthcare Ltd Use
JP5421366B2 (ja) 2008-07-21 2014-02-19 オトノミ―，インク． 制御放出性の耳の構造体調節および生来の免疫システム調節化合物および耳の障害の処置のための方法
US8784870B2 (en) 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
US7914828B2 (en) * 2008-10-17 2011-03-29 Levine Brian M Combination herbal product to benefit respiratory tract
GB2477590A (en) * 2010-02-05 2011-08-10 Biocopea Ltd A non-steroidal anti-inflammatory drug (NSAID) formulation comprising a lipid carrier
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9737500B2 (en) 2010-10-29 2017-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US8895536B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating chronic inflammation and inflammatory diseases
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US8361519B2 (en) 2010-11-18 2013-01-29 Aadvantics Pharmaceuticals, Inc. Combination herbal product to benefit respiratory tract in people exposed to smoke
US20140213644A1 (en) * 2010-12-30 2014-07-31 Ziv Harish Formulations and Methods for Prevention and Treatment of Oral Allergy Syndrome
US11033594B2 (en) * 2012-12-06 2021-06-15 Colgate-Palmolive Company Oral gel for sensitivity and tooth pain
EP3061501A1 (de) 2015-02-27 2016-08-31 Rottapharm Ltd. Zusammensetzung zur behandlung von akne
EP3117825A1 (de) 2015-07-16 2017-01-18 Rottapharm S.p.A. Orale formulierung mit berberin und morus-alba-extrakt
CA2993645A1 (en) 2015-07-28 2017-02-02 Otonomy, Inc. Trkb or trkc agonist compositions and methods for the treatment of otic conditions
CA3009072A1 (en) * 2015-12-30 2017-07-06 Colgate-Palmolive Company Mucin coated silica for bacterial aggregation
JP7033789B2 (ja) 2016-06-29 2022-03-11 オトノミー，インク． トリグリセリド耳用製剤とその使用
US10583081B1 (en) * 2017-11-27 2020-03-10 Richard A. Myers Apparatus and formulation for treating mouth ulcers
CA3087574A1 (en) 2018-01-09 2019-07-18 Otonomy, Inc. Growth factor otic formulations
WO2019154895A1 (en) 2018-02-08 2019-08-15 Strekin Ag Gel formulation for preventing or treating hearing loss
US20210244710A1 (en) * 2018-07-02 2021-08-12 Kangping Xiao Stable pharmaceutical formulations of oxymetazoline
US12036329B2 (en) 2018-09-11 2024-07-16 Lead Biotherapeutics Ltd Mucoadhesive dispersion nanoparticle system and method for production the same
CN113271979A (zh) 2018-10-24 2021-08-17 费灵有限公司 皮质类固醇的粘膜粘附性药物组合物
ES3030910T3 (en) * 2019-02-15 2025-07-02 Ferrer Medical Innovations Llc Nasal spray compositions and related treatment methods

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3352752A (en) 1963-07-25 1967-11-14 Tintex Corp Intestinal adsorbent compositions
JPS589083B2 (ja) 1975-05-30 1983-02-18 武田薬品工業株式会社 シヨウリユウザイノセイゾウホウ
FR2346017A1 (fr) 1975-10-23 1977-10-28 Rech Applic Scient Composition therapeutique pour le traitement des affections du tractus gastro-intestinal
FR2502956A1 (fr) 1981-04-01 1982-10-08 Human Pharm Sa Laboratoires Composition therapeutique utile comme topique digestif
US4427681A (en) 1982-09-16 1984-01-24 Richardson-Vicks, Inc. Thixotropic compositions easily convertible to pourable liquids
JPS61106509A (ja) * 1984-10-29 1986-05-24 Fujisawa Pharmaceut Co Ltd 鼻腔用医薬組成物
DK164199C (da) 1986-05-16 1992-10-19 Chugai Pharmaceutical Co Ltd Sucralfatpraeparat til anvendelse paa oesophagus mucosa
US5464828A (en) 1988-03-02 1995-11-07 Chugai Pharmaceutical Co., Ltd. Aqueous suspension of sucralfate
US5719197A (en) 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5047244A (en) 1988-06-03 1991-09-10 Watson Laboratories, Inc. Mucoadhesive carrier for delivery of therapeutical agent
FI913127A0 (fi) 1989-10-31 1991-06-27 Watson Lab Vid slemhinnan haeftade stoedsystem foer frigoerande av ett terapeutiskt aemne.
JPH0639368B2 (ja) 1990-02-28 1994-05-25 株式会社萩原技研 シリカゲルを母体とした抗菌性組生物
GB9025710D0 (en) 1990-11-27 1991-01-09 Beecham Group Plc Novel treatment
DK0586488T3 (da) 1991-06-07 1995-09-04 Byk Nederland Bv Farmaceutisk klysterpræparat
IT1251153B (it) 1991-08-06 1995-05-04 Vectorpharma Int Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica
JPH0725769A (ja) * 1992-10-20 1995-01-27 Fuji Chem Ind Co Ltd アロプリノール医薬用液剤ならびにその製造法
FR2710265B1 (fr) 1993-09-22 1995-10-20 Adir Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs.
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
US5670163A (en) 1994-06-20 1997-09-23 Kv Pharmaceuticals Company Long acting GI and esophageal protectant
US5554379A (en) 1994-06-20 1996-09-10 Kv Pharmaceutical Company Long acting GI and esophageal protectant
US5554380A (en) 1994-08-04 1996-09-10 Kv Pharmaceutical Company Bioadhesive pharmaceutical delivery system
US5585108A (en) 1994-12-30 1996-12-17 Nanosystems L.L.C. Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
US5466440A (en) 1994-12-30 1995-11-14 Eastman Kodak Company Formulations of oral gastrointestinal diagnostic X-ray contrast agents in combination with pharmaceutically acceptable clays
JP3927253B2 (ja) * 1995-02-02 2007-06-06 中外製薬株式会社 スクラルファート製剤
US5580579A (en) 1995-02-15 1996-12-03 Nano Systems L.L.C. Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers
IT1275955B1 (it) * 1995-03-22 1997-10-24 Dompe Spa Formulazioni farmaceutiche in forma di gel tissotropico
FR2739558B1 (fr) 1995-10-05 1997-11-28 Innothera Lab Sa Forme galenique unitaire pour hormonotherapie locale de la secheresse vaginale

Also Published As

Publication number Publication date
NO20010832L (no) 2001-02-19
TR200100628T2 (tr) 2001-10-22
EP1107733B1 (de) 2005-07-27
CO5140082A1 (es) 2002-03-22
NO20010832D0 (no) 2001-02-19
KR100413877B1 (ko) 2004-01-07
BR9913178B1 (pt) 2014-11-25
ID29576A (id) 2001-09-06
EP1107733A1 (de) 2001-06-20
AU5580999A (en) 2000-03-14
WO2000010529A1 (en) 2000-03-02
PE20000862A1 (es) 2000-09-13
CN1313756A (zh) 2001-09-19
DE69926377T2 (de) 2006-06-01
HUP0103388A2 (hu) 2002-01-28
CA2338704A1 (en) 2000-03-02
BR9913178A (pt) 2001-05-15
US6319513B1 (en) 2001-11-20
AU761968B2 (en) 2003-06-12
JP2002523354A (ja) 2002-07-30
CA2338704C (en) 2004-11-02
KR20010072678A (ko) 2001-07-31
DE69926377D1 (de) 2005-09-01
HUP0103388A3 (en) 2006-02-28
CN1195494C (zh) 2005-04-06

Similar Documents

Publication Publication Date Title
DE69926377D1 (de) Orale flüssige mucoadhäsive zusammensetzungen
ATE227978T1 (de) Orale flüssige mucoadhäsive zusammensetzungen
ES2303645T3 (es) Composiciones para prevenir y tratar sintomas de tipo resfriado y gripe que comprenden cinc quelado.
JPH0161086B2 (de)
CA2323680A1 (en) Orally disintegrable tablets
JPH03197430A (ja) 呼吸器管感染症用スプレー剤
CA2321819A1 (en) Xylitol compositions for treating upper respiratory conditions
CA2277365A1 (en) Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1
FR2712807B1 (fr) Composition solide mucoadhésive, thérapeutique ou hygiénique, pour administration par application sur la muqueuse buccale ou nasale .
ATE226429T1 (de) Orale flüssige mucoadhäsive zusammensetzungen
WO2003015746A1 (en) Nasal passage cleaning composition
WO2003101434A3 (en) Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor
WO2001012128A3 (en) Antibacterial agents for the treatment of acute mucosal infections
JP2001139465A (ja) 咽頭粘膜用組成物
JP2002145764A (ja) 咽頭粘膜用組成物
GB2243548A (en) Therapeutic nasal drops containing sulphonamides
JP2007022971A (ja) 経鼻投与のための組成物
BR0205625C1 (pt) Formulações nasais em gel

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties