DE69916005D1 - Effizientes Verfahren zum Auffinden von Genfunktionen mittels Bibliotheken zur funktionellen Genomanwendung - Google Patents
Effizientes Verfahren zum Auffinden von Genfunktionen mittels Bibliotheken zur funktionellen GenomanwendungInfo
- Publication number
- DE69916005D1 DE69916005D1 DE69916005T DE69916005T DE69916005D1 DE 69916005 D1 DE69916005 D1 DE 69916005D1 DE 69916005 T DE69916005 T DE 69916005T DE 69916005 T DE69916005 T DE 69916005T DE 69916005 D1 DE69916005 D1 DE 69916005D1
- Authority
- DE
- Germany
- Prior art keywords
- libraries
- efficient method
- nucleic acids
- gene functions
- sample nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/097,239 US6413776B1 (en) | 1998-06-12 | 1998-06-12 | High throughput screening of gene function using adenoviral libraries for functional genomics applications |
US97239 | 1998-06-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69916005D1 true DE69916005D1 (de) | 2004-05-06 |
DE69916005T2 DE69916005T2 (de) | 2004-09-09 |
Family
ID=22262382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69916005T Expired - Lifetime DE69916005T2 (de) | 1998-06-12 | 1999-06-11 | Effizientes Verfahren zum Auffinden von Genfunktionen mittels Bibliotheken zur funktionellen Genomanwendung |
Country Status (10)
Country | Link |
---|---|
US (3) | US6413776B1 (de) |
EP (1) | EP1022335B1 (de) |
JP (1) | JP3672494B2 (de) |
AT (1) | ATE263237T1 (de) |
AU (1) | AU756605B2 (de) |
CA (1) | CA2301403C (de) |
DE (1) | DE69916005T2 (de) |
MX (1) | MXPA00012401A (de) |
NZ (1) | NZ508995A (de) |
WO (1) | WO1999064582A2 (de) |
Families Citing this family (96)
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US6783980B2 (en) * | 1995-06-15 | 2004-08-31 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
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AU3548799A (en) * | 1998-04-03 | 1999-10-25 | Invitrogen Corporation | Libraries of expressible gene sequences |
US6670188B1 (en) * | 1998-04-24 | 2003-12-30 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
CN1230546C (zh) | 1998-10-06 | 2005-12-07 | 马克·阿龙·埃马尔法尔布 | 丝状真菌宿主领域的转化系统 |
JP2002535003A (ja) * | 1999-01-29 | 2002-10-22 | マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ | アポトーシスを誘導するdna配列の単離方法及び検出システム |
US6642052B2 (en) * | 1999-02-25 | 2003-11-04 | National Research Council Of Canada | Efficient generation of adenovirus-based libraries by positive selection of adenoviral recombinants through ectopic expression of the adenovirus protease |
US6492169B1 (en) | 1999-05-18 | 2002-12-10 | Crucell Holland, B.V. | Complementing cell lines |
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JP2003524422A (ja) | 2000-02-25 | 2003-08-19 | インヴィトロジェン コーポレーション | トポイソメラーゼリンカー介在型増幅法 |
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ES2609014T3 (es) | 2001-07-12 | 2017-04-18 | University Of Massachusetts | Producción in vivo de ARN de interferencia pequeños que median el silenciamiento génico |
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US6197502B1 (en) | 1997-11-17 | 2001-03-06 | Cytos Biotechnology Ag | Expression cloning processes for the discovery characterization, and isolation of genes encoding polypeptides with a predetermined property |
CA2315242C (en) * | 1997-12-19 | 2005-02-08 | Genetrace Systems, Inc. | Non-bacterial cloning in delivery and expression of nucleic acids |
US6670188B1 (en) * | 1998-04-24 | 2003-12-30 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
-
1998
- 1998-06-12 US US09/097,239 patent/US6413776B1/en not_active Expired - Lifetime
-
1999
- 1999-06-11 JP JP2000553572A patent/JP3672494B2/ja not_active Expired - Fee Related
- 1999-06-11 EP EP99201866A patent/EP1022335B1/de not_active Expired - Lifetime
- 1999-06-11 MX MXPA00012401A patent/MXPA00012401A/es active IP Right Grant
- 1999-06-11 WO PCT/NL1999/000367 patent/WO1999064582A2/en active IP Right Grant
- 1999-06-11 DE DE69916005T patent/DE69916005T2/de not_active Expired - Lifetime
- 1999-06-11 NZ NZ508995A patent/NZ508995A/en not_active IP Right Cessation
- 1999-06-11 CA CA002301403A patent/CA2301403C/en not_active Expired - Lifetime
- 1999-06-11 AU AU42947/99A patent/AU756605B2/en not_active Expired
- 1999-06-11 AT AT99201866T patent/ATE263237T1/de not_active IP Right Cessation
- 1999-07-21 US US09/358,036 patent/US6340595B1/en not_active Expired - Lifetime
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2001
- 2001-12-21 US US10/036,949 patent/US7029848B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
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NZ508995A (en) | 2003-12-19 |
US6413776B1 (en) | 2002-07-02 |
JP2002526031A (ja) | 2002-08-20 |
AU4294799A (en) | 1999-12-30 |
EP1022335B1 (de) | 2004-03-31 |
US7029848B2 (en) | 2006-04-18 |
JP3672494B2 (ja) | 2005-07-20 |
CA2301403A1 (en) | 1999-12-16 |
MXPA00012401A (es) | 2003-07-14 |
WO1999064582A3 (en) | 2000-04-06 |
US6340595B1 (en) | 2002-01-22 |
US20030027170A1 (en) | 2003-02-06 |
AU756605B2 (en) | 2003-01-16 |
CA2301403C (en) | 2009-01-06 |
DE69916005T2 (de) | 2004-09-09 |
WO1999064582A2 (en) | 1999-12-16 |
ATE263237T1 (de) | 2004-04-15 |
EP1022335A1 (de) | 2000-07-26 |
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