DE69914493T2 - Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin - Google Patents
Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin Download PDFInfo
- Publication number
- DE69914493T2 DE69914493T2 DE69914493T DE69914493T DE69914493T2 DE 69914493 T2 DE69914493 T2 DE 69914493T2 DE 69914493 T DE69914493 T DE 69914493T DE 69914493 T DE69914493 T DE 69914493T DE 69914493 T2 DE69914493 T2 DE 69914493T2
- Authority
- DE
- Germany
- Prior art keywords
- trifluoromethylpyridine
- fluoro
- hydroxy
- chloro
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B41/00—Formation or introduction of functional groups containing oxygen
- C07B41/02—Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9819235.4A GB9819235D0 (en) | 1998-09-03 | 1998-09-03 | Chemical process |
| GB9819235 | 1998-09-03 | ||
| PCT/GB1999/002894 WO2000014068A1 (en) | 1998-09-03 | 1999-09-02 | Chemical process for preparing 2-hydroxy-6-trifluoromethylpyridine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69914493D1 DE69914493D1 (de) | 2004-03-04 |
| DE69914493T2 true DE69914493T2 (de) | 2004-07-22 |
Family
ID=10838299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69914493T Expired - Lifetime DE69914493T2 (de) | 1998-09-03 | 1999-09-02 | Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6143899A (enExample) |
| EP (1) | EP1109788B1 (enExample) |
| JP (1) | JP4302322B2 (enExample) |
| KR (1) | KR100567197B1 (enExample) |
| CN (1) | CN1134416C (enExample) |
| AT (1) | ATE258547T1 (enExample) |
| AU (1) | AU5638399A (enExample) |
| BR (1) | BR9913401B1 (enExample) |
| DE (1) | DE69914493T2 (enExample) |
| DK (1) | DK1109788T3 (enExample) |
| ES (1) | ES2215397T3 (enExample) |
| GB (1) | GB9819235D0 (enExample) |
| IL (2) | IL141597A0 (enExample) |
| WO (1) | WO2000014068A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0016336D0 (en) | 2000-07-03 | 2000-08-23 | Zeneca Ltd | Chemical process |
| GB0016338D0 (en) | 2000-07-03 | 2000-08-23 | Zeneca Ltd | Chemical process |
| WO2015151116A2 (en) * | 2014-03-31 | 2015-10-08 | Jubilant Life Sciences Limited | Process for producing 2-fluoro-6-(trifluoromethyl)pyridine compounds |
| CN107759513A (zh) * | 2017-11-17 | 2018-03-06 | 山东汇盟生物科技有限公司 | 一种2‑羟基‑6‑三氟甲基吡啶的制备方法 |
| CN108997203B (zh) * | 2018-06-26 | 2020-08-14 | 江苏扬农化工集团有限公司 | 一种2,3-二氯-5-三氟甲基吡啶的高效提纯方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB288628A (en) * | 1927-04-14 | 1929-07-03 | Schering Kahlbaum Ag | Process for the manufacture of hydroxypyridine compounds |
| US3355456A (en) * | 1965-05-06 | 1967-11-28 | Dow Chemical Co | Production of monohalopyridinols |
| US3711486A (en) * | 1969-03-17 | 1973-01-16 | Dow Chemical Co | Substituted(trifluoromethyl)pyridines |
| US3609158A (en) * | 1969-03-17 | 1971-09-28 | Dow Chemical Co | Certain substituted (pyridyl)-oxy acetic acid derivatives |
| GB1303679A (enExample) * | 1970-06-30 | 1973-01-17 | ||
| US4108629A (en) * | 1973-03-19 | 1978-08-22 | The Dow Chemical Company | Herbicidal use of esters of aminohalopyridyloxy acids |
| US4038396A (en) * | 1975-02-24 | 1977-07-26 | Merck & Co., Inc. | Anti-inflammatory oxazole[4,5-b]pyridines |
| US4249009A (en) * | 1979-01-29 | 1981-02-03 | Reilly Tar & Chemical Corp. | Processes for preparing 2-chloro-5-trifluoromethylpyridine |
| US4474599A (en) * | 1982-07-14 | 1984-10-02 | The Dow Chemical Company | 1-(Pyridyl)-1H-1,2,3-triazole derivatives, and use as herbicidal agents |
| US4455313A (en) * | 1982-08-20 | 1984-06-19 | The Dow Chemical Company | Fungicidal control employing substituted pyridinols |
| JPS6348268A (ja) * | 1986-08-14 | 1988-02-29 | Ishihara Sangyo Kaisha Ltd | Ｎ−ピリジル−ｎ’−ベンゾイルウレア系化合物及びそれらを含有する殺虫剤 |
| JPH0822851B2 (ja) * | 1987-09-16 | 1996-03-06 | 北興化学工業株式会社 | ２，３，５−トリクロロピリジンの製造方法 |
| DE3814358A1 (de) * | 1988-04-28 | 1989-11-09 | Ruetgerswerke Ag | Verfahren zur herstellung von 2-hydroxypyridin |
| US4976946A (en) * | 1990-02-09 | 1990-12-11 | The Dow Chemical Company | Separation of potassium salts |
| GB9704795D0 (en) * | 1997-03-07 | 1997-04-23 | Zeneca Ltd | Chemical process |
-
1998
- 1998-09-03 GB GBGB9819235.4A patent/GB9819235D0/en not_active Ceased
-
1999
- 1999-09-02 KR KR1020017002721A patent/KR100567197B1/ko not_active Expired - Lifetime
- 1999-09-02 IL IL14159799A patent/IL141597A0/xx active IP Right Grant
- 1999-09-02 BR BRPI9913401-2A patent/BR9913401B1/pt not_active IP Right Cessation
- 1999-09-02 JP JP2000568827A patent/JP4302322B2/ja not_active Expired - Lifetime
- 1999-09-02 CN CNB998101761A patent/CN1134416C/zh not_active Expired - Lifetime
- 1999-09-02 AT AT99943100T patent/ATE258547T1/de active
- 1999-09-02 DE DE69914493T patent/DE69914493T2/de not_active Expired - Lifetime
- 1999-09-02 AU AU56383/99A patent/AU5638399A/en not_active Abandoned
- 1999-09-02 ES ES99943100T patent/ES2215397T3/es not_active Expired - Lifetime
- 1999-09-02 EP EP99943100A patent/EP1109788B1/en not_active Expired - Lifetime
- 1999-09-02 WO PCT/GB1999/002894 patent/WO2000014068A1/en not_active Ceased
- 1999-09-02 DK DK99943100T patent/DK1109788T3/da active
- 1999-09-03 US US09/390,049 patent/US6143899A/en not_active Expired - Lifetime
-
2001
- 2001-02-22 IL IL141597A patent/IL141597A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR9913401A (pt) | 2001-05-22 |
| US6143899A (en) | 2000-11-07 |
| JP4302322B2 (ja) | 2009-07-22 |
| DK1109788T3 (da) | 2004-06-01 |
| ATE258547T1 (de) | 2004-02-15 |
| AU5638399A (en) | 2000-03-27 |
| CN1314889A (zh) | 2001-09-26 |
| WO2000014068A1 (en) | 2000-03-16 |
| IL141597A0 (en) | 2002-03-10 |
| EP1109788B1 (en) | 2004-01-28 |
| KR100567197B1 (ko) | 2006-04-03 |
| DE69914493D1 (de) | 2004-03-04 |
| BR9913401B1 (pt) | 2010-07-13 |
| IL141597A (en) | 2006-08-20 |
| GB9819235D0 (en) | 1998-10-28 |
| JP2002524447A (ja) | 2002-08-06 |
| EP1109788A1 (en) | 2001-06-27 |
| KR20010074916A (ko) | 2001-08-09 |
| ES2215397T3 (es) | 2004-10-01 |
| CN1134416C (zh) | 2004-01-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69919151T2 (de) | Verfahren zur synthese von cox-2 inhibitoren | |
| DE69813312T2 (de) | Verfahren zur herstellung von cyclopropylethyn sowie zwischenprodukte zur herstellung von cyclopropylethyn | |
| DE1301807B (de) | Verfahren zur Herstellung von Perfluoralkyl-alkyl-aethern | |
| DE69914493T2 (de) | Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin | |
| DE69029052T2 (de) | Verfahren zur Herstellung von 3,5,6-Trichloropyridin-2-ol | |
| EP0034741B1 (de) | Verfahren zur Herstellung eines substituierten Bromfluorbenzols und 3-Brom-4-fluorbenzonitril | |
| DE3514450A1 (de) | Verfahren zur herstellung von imidaten sowie neue arylsubstituierte imidate | |
| DE68917567T2 (de) | Verfahren zur Herstellung von Difluorbenzolen mit elektronenabziehenden Substituenten. | |
| EP0178260B1 (de) | Verfahren zur Herstellung von fluorierten Pyridin-Derivaten | |
| DE2437882B2 (de) | Verfahren zur herstellung von estern des 3-phenoxybenzylalkohols | |
| DE2836077C2 (de) | Herstellung von 2,3,5-Trichlorpyridin | |
| EP0569947B1 (de) | Verfahren zur Herstellung von 2-Chlor-5-chlormethyl-pyridin | |
| EP1223158B1 (de) | Verfahren zur Herstellung trifluormethyl-substituierter Biphenylcarbonsäuren und neue trichlormethyl- und trifluormethyl-substituierte Biphenylcarbonitrile | |
| EP0556737B1 (de) | Verfahren zur Herstellung von substituierten 2,3-Difluorpyridinen | |
| EP0579020B1 (de) | Verfahren zur Herstellung von 5-(Trifluormethyl)-uracil und die neuen Verbindungen 2,4-Dichlor-5-trichlormethylpyrimidin und 2,4-Difluor-5-trifluormethyl-pyrimidin | |
| DE2443142C2 (de) | Verfahren zur Herstellung von Cyclopropancarbonsäurenitril | |
| EP0557949A2 (de) | Verfahren zur Herstellung von 2,4,5-Trifluorbenzonitril | |
| DE69115758T2 (de) | Verfahren zur Herstellung von 3,5-Difluoranilin und dessen Derivat | |
| EP0066248A1 (de) | Verfahren zur Herstellung von Halogen-2-merkaptobenzoxazolen | |
| DE69810084T2 (de) | Verfahren zur herstellung von 2-hydroxy-6-trifluormethylpyridin | |
| EP0529631A1 (de) | Verfahren zur Herstellung von 2-(Methylthio)-dinatriumbarbiturat | |
| DE69501029T2 (de) | Verfahren zur herstellung von cyanopyridin | |
| DE2756560A1 (de) | Verfahren zur herstellung von piperonal | |
| DE2053715A1 (de) | Herstellung von 2-alk>lsubstituier ten Thiazolen und Selenazolen | |
| EP0115811B1 (de) | 2,4-Dichlor-5-thiazolcarboxaldehyd und ein Verfahren zu seiner Herstellung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |