BR9913401A - Processo para a preparação de 2hidróxi-6-trifluorometilpiridina - Google Patents

Processo para a preparação de 2hidróxi-6-trifluorometilpiridina

Info

Publication number
BR9913401A
BR9913401A BR9913401-2A BR9913401A BR9913401A BR 9913401 A BR9913401 A BR 9913401A BR 9913401 A BR9913401 A BR 9913401A BR 9913401 A BR9913401 A BR 9913401A
Authority
BR
Brazil
Prior art keywords
trifluoromethylpyridine
hydroxy
preparation
fluoro
trifluomethylpyridine
Prior art date
Application number
BR9913401-2A
Other languages
English (en)
Other versions
BR9913401B1 (pt
Inventor
Erwin Michael Seidel
David Dale Friese
Alexander Pai-Yng Fung
John Desmond Hunt
Raymond Vincent Heavon Jones
Alan John Whitton
Alastair Iain Currie Stewart
Jennifer Ann White
Original Assignee
Zeneca Ltd
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd, Dow Agrosciences Llc filed Critical Zeneca Ltd
Publication of BR9913401A publication Critical patent/BR9913401A/pt
Publication of BR9913401B1 publication Critical patent/BR9913401B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00—Formation or introduction of functional groups containing oxygen
    • C07B41/02—Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE 2-HIDRóXI-6-TRIFLUOROMETILPIRIDINA''. Um processo para a preparação de 2-hidróxi-6-trifluorometilpiridina que compreende reagir 2-fluoro-6-trifluorometilpiridina ou uma mistura de 2-fluoro-6-trifluorometilpiridina e 2-cloro-6-trifluorometilpiridina com um hidróxido de metal alcalino a uma temperatura de 50°C a 160°C e acidificar o produto assim formado.
BRPI9913401-2A 1998-09-03 1999-09-02 processo para a preparação de 2-hidróxi-6-trifluorometilpiridina. BR9913401B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9819235.4A GB9819235D0 (en) 1998-09-03 1998-09-03 Chemical process
PCT/GB1999/002894 WO2000014068A1 (en) 1998-09-03 1999-09-02 Chemical process for preparing 2-hydroxy-6-trifluoromethylpyridine

Publications (2)

Publication Number Publication Date
BR9913401A true BR9913401A (pt) 2001-05-22
BR9913401B1 BR9913401B1 (pt) 2010-07-13

Family

ID=10838299

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9913401-2A BR9913401B1 (pt) 1998-09-03 1999-09-02 processo para a preparação de 2-hidróxi-6-trifluorometilpiridina.

Country Status (14)

Country Link
US (1) US6143899A (pt)
EP (1) EP1109788B1 (pt)
JP (1) JP4302322B2 (pt)
KR (1) KR100567197B1 (pt)
CN (1) CN1134416C (pt)
AT (1) ATE258547T1 (pt)
AU (1) AU5638399A (pt)
BR (1) BR9913401B1 (pt)
DE (1) DE69914493T2 (pt)
DK (1) DK1109788T3 (pt)
ES (1) ES2215397T3 (pt)
GB (1) GB9819235D0 (pt)
IL (2) IL141597A0 (pt)
WO (1) WO2000014068A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0016336D0 (en) 2000-07-03 2000-08-23 Zeneca Ltd Chemical process
GB0016338D0 (en) 2000-07-03 2000-08-23 Zeneca Ltd Chemical process
WO2015151116A2 (en) * 2014-03-31 2015-10-08 Jubilant Life Sciences Limited Process for producing 2-fluoro-6-(trifluoromethyl)pyridine compounds
CN107759513A (zh) * 2017-11-17 2018-03-06 山东汇盟生物科技有限公司 一种2‑羟基‑6‑三氟甲基吡啶的制备方法
CN108997203B (zh) * 2018-06-26 2020-08-14 江苏扬农化工集团有限公司 一种2,3-二氯-5-三氟甲基吡啶的高效提纯方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB288628A (en) * 1927-04-14 1929-07-03 Schering Kahlbaum Ag Process for the manufacture of hydroxypyridine compounds
US3355456A (en) * 1965-05-06 1967-11-28 Dow Chemical Co Production of monohalopyridinols
US3711486A (en) * 1969-03-17 1973-01-16 Dow Chemical Co Substituted(trifluoromethyl)pyridines
US3609158A (en) * 1969-03-17 1971-09-28 Dow Chemical Co Certain substituted (pyridyl)-oxy acetic acid derivatives
GB1303679A (pt) * 1970-06-30 1973-01-17
US4108629A (en) * 1973-03-19 1978-08-22 The Dow Chemical Company Herbicidal use of esters of aminohalopyridyloxy acids
US4038396A (en) * 1975-02-24 1977-07-26 Merck & Co., Inc. Anti-inflammatory oxazole[4,5-b]pyridines
US4249009A (en) * 1979-01-29 1981-02-03 Reilly Tar & Chemical Corp. Processes for preparing 2-chloro-5-trifluoromethylpyridine
US4474599A (en) * 1982-07-14 1984-10-02 The Dow Chemical Company 1-(Pyridyl)-1H-1,2,3-triazole derivatives, and use as herbicidal agents
US4455313A (en) * 1982-08-20 1984-06-19 The Dow Chemical Company Fungicidal control employing substituted pyridinols
JPS6348268A (ja) * 1986-08-14 1988-02-29 Ishihara Sangyo Kaisha Ltd Ｎ−ピリジル−ｎ’−ベンゾイルウレア系化合物及びそれらを含有する殺虫剤
JPH0822851B2 (ja) * 1987-09-16 1996-03-06 北興化学工業株式会社 ２，３，５−トリクロロピリジンの製造方法
DE3814358A1 (de) * 1988-04-28 1989-11-09 Ruetgerswerke Ag Verfahren zur herstellung von 2-hydroxypyridin
US4976946A (en) * 1990-02-09 1990-12-11 The Dow Chemical Company Separation of potassium salts
GB9704795D0 (en) * 1997-03-07 1997-04-23 Zeneca Ltd Chemical process

Also Published As

Publication number Publication date
DK1109788T3 (da) 2004-06-01
DE69914493T2 (de) 2004-07-22
JP4302322B2 (ja) 2009-07-22
AU5638399A (en) 2000-03-27
WO2000014068A1 (en) 2000-03-16
BR9913401B1 (pt) 2010-07-13
EP1109788B1 (en) 2004-01-28
DE69914493D1 (de) 2004-03-04
IL141597A0 (en) 2002-03-10
CN1314889A (zh) 2001-09-26
JP2002524447A (ja) 2002-08-06
US6143899A (en) 2000-11-07
IL141597A (en) 2006-08-20
ES2215397T3 (es) 2004-10-01
EP1109788A1 (en) 2001-06-27
KR100567197B1 (ko) 2006-04-03
GB9819235D0 (en) 1998-10-28
CN1134416C (zh) 2004-01-14
KR20010074916A (ko) 2001-08-09
ATE258547T1 (de) 2004-02-15

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved
B25G Requested change of headquarter approved
B25G Requested change of headquarter approved
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/07/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 13.07.2020