BR9712773A - Processo para a sìntese de benzotiofenos - Google Patents
Processo para a sìntese de benzotiofenosInfo
- Publication number
- BR9712773A BR9712773A BR9712773-6A BR9712773A BR9712773A BR 9712773 A BR9712773 A BR 9712773A BR 9712773 A BR9712773 A BR 9712773A BR 9712773 A BR9712773 A BR 9712773A
- Authority
- BR
- Brazil
- Prior art keywords
- benzothiophenes
- synthesis
- benzotiophenes
- preparation
- provides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
Abstract
Patente de Invenção:<B>"PROCESSO PARA A SìNTESE DE BENZOTIOFENOS"<D>. A presente invenção proporciona um processo aperfeiçoadp para a preparação de benzotiofenos utilizando ácido metanossulfónico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3118196P | 1996-11-19 | 1996-11-19 | |
PCT/US1997/021820 WO1998022456A1 (en) | 1996-11-19 | 1997-11-14 | Process for the synthesis of benzothiophenes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9712773A true BR9712773A (pt) | 1999-10-26 |
Family
ID=21858059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9712773-6A BR9712773A (pt) | 1996-11-19 | 1997-11-14 | Processo para a sìntese de benzotiofenos |
Country Status (23)
Country | Link |
---|---|
US (1) | US5969157A (pt) |
EP (1) | EP0842930B1 (pt) |
JP (1) | JP2001504497A (pt) |
KR (1) | KR20000053333A (pt) |
CN (1) | CN1130357C (pt) |
AR (1) | AR010615A1 (pt) |
AT (1) | ATE217620T1 (pt) |
AU (1) | AU726401B2 (pt) |
BR (1) | BR9712773A (pt) |
CA (1) | CA2271922A1 (pt) |
CO (1) | CO4920247A1 (pt) |
DE (1) | DE69712590T2 (pt) |
DK (1) | DK0842930T3 (pt) |
ES (1) | ES2173399T3 (pt) |
HU (1) | HUP9904510A3 (pt) |
ID (1) | ID18917A (pt) |
IL (1) | IL129868A (pt) |
PE (1) | PE16799A1 (pt) |
PT (1) | PT842930E (pt) |
SI (1) | SI0842930T1 (pt) |
TW (1) | TW461888B (pt) |
WO (1) | WO1998022456A1 (pt) |
ZA (1) | ZA9710262B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001009116A2 (en) * | 1999-07-29 | 2001-02-08 | Eli Lilly And Company | A NOVEL CRYSTALLINE FORM OF 6-HYDROXY-3- (4-[2-(PIPERIDIN-1-YL) ETHOXY]PHENOXY)- 2-(4-METHOXYPHENYL)BENZO[b]THIOPHENE HYDROCHLORIDE |
WO2002042289A2 (en) * | 2000-11-27 | 2002-05-30 | Eli Lilly And Company | Process for preparing 3-aryl-benzo[b]thiophenes |
US20050069962A1 (en) | 2001-10-12 | 2005-03-31 | Archer Robert M | Antibody complexes and methods for immunolabeling |
US8323903B2 (en) | 2001-10-12 | 2012-12-04 | Life Technologies Corporation | Antibody complexes and methods for immunolabeling |
CA2492631C (en) * | 2002-05-31 | 2013-03-12 | Genetic Technologies Limited | Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood |
CA2499819A1 (en) | 2002-09-30 | 2004-04-08 | A/S Gea Farmaceutisk Fabrik | Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these |
AU2004217872B2 (en) * | 2003-03-05 | 2010-03-25 | Genetic Technologies Limited | Identification of fetal DNA and fetal cell markers in maternal plasma or serum |
KR20090082399A (ko) | 2006-10-17 | 2009-07-30 | 씨아이피엘에이 엘티디. | 벤조티오펜 화합물의 결정형 및 그의 제조방법 |
US9447467B2 (en) | 2009-04-21 | 2016-09-20 | Genetic Technologies Limited | Methods for obtaining fetal genetic material |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU509682B2 (en) * | 1975-10-28 | 1980-05-22 | Eli Lilly And Company | 2-Aroyl-3-Phenylbenzothiophene Derivatives |
US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
AT364852B (de) * | 1977-11-05 | 1981-11-25 | Thomae Gmbh Dr K | Verfahren zur herstellung von kondensierten isothiazol-3(2h)-on-1,1-dioxiden und von deren salzen |
US4436748A (en) * | 1980-10-20 | 1984-03-13 | Hoechst-Roussel Pharmaceuticals Inc. | Benzo[b]thiophenes |
US4380635A (en) * | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
IL65378A (en) * | 1981-04-03 | 1986-02-28 | Lilly Co Eli | Process for preparing 3-(4-aminoethoxybenzoyl)benzo-(b)thiophenes |
US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
US4544746A (en) * | 1982-05-17 | 1985-10-01 | Ciba-Geigy Corporation | Process for preparing 2-anilinoacridone |
JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
DE4204969A1 (de) * | 1992-02-19 | 1993-08-26 | Basf Ag | Verfahren zur herstellung von benzo(b)thiophenen |
US5466810A (en) * | 1994-06-10 | 1995-11-14 | Eli Lilly And Company | 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)-benzoyl]benzo[β]thiophenes |
DE4423893C2 (de) * | 1994-07-07 | 1996-09-05 | Freudenberg Carl Fa | Flachdichtung mit flexibler Leiterplatte |
US5523416A (en) * | 1994-07-22 | 1996-06-04 | Eli Lilly And Company | Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes |
US5552401A (en) * | 1995-02-28 | 1996-09-03 | Eli Lilly And Company | 2-benzyl-3-arylbenzothiophenes |
US5614639A (en) * | 1995-03-31 | 1997-03-25 | Eli Lilly And Company | Process for preparing 2-substituted benzo[b]thiophene compounds and intermediates thereof |
US5606075A (en) * | 1995-06-07 | 1997-02-25 | Eli Lilly And Company | Process for the synthesis of benzo[b]thiophenes |
US5606076A (en) * | 1995-06-07 | 1997-02-25 | Eli Lilly And Company | Process for the synthesis of benzo[b]thiophenes |
-
1997
- 1997-11-13 ZA ZA9710262A patent/ZA9710262B/xx unknown
- 1997-11-14 ES ES97309186T patent/ES2173399T3/es not_active Expired - Lifetime
- 1997-11-14 CO CO97067013A patent/CO4920247A1/es unknown
- 1997-11-14 HU HU9904510A patent/HUP9904510A3/hu unknown
- 1997-11-14 JP JP52400398A patent/JP2001504497A/ja active Pending
- 1997-11-14 WO PCT/US1997/021820 patent/WO1998022456A1/en not_active Application Discontinuation
- 1997-11-14 CN CN97199842A patent/CN1130357C/zh not_active Expired - Fee Related
- 1997-11-14 SI SI9730342T patent/SI0842930T1/xx unknown
- 1997-11-14 PE PE1997001035A patent/PE16799A1/es not_active Application Discontinuation
- 1997-11-14 IL IL12986897A patent/IL129868A/en not_active IP Right Cessation
- 1997-11-14 PT PT97309186T patent/PT842930E/pt unknown
- 1997-11-14 DK DK97309186T patent/DK0842930T3/da active
- 1997-11-14 AT AT97309186T patent/ATE217620T1/de active
- 1997-11-14 DE DE69712590T patent/DE69712590T2/de not_active Expired - Lifetime
- 1997-11-14 KR KR1019990704344A patent/KR20000053333A/ko not_active Application Discontinuation
- 1997-11-14 EP EP97309186A patent/EP0842930B1/en not_active Expired - Lifetime
- 1997-11-14 BR BR9712773-6A patent/BR9712773A/pt unknown
- 1997-11-14 CA CA002271922A patent/CA2271922A1/en not_active Abandoned
- 1997-11-14 AU AU54622/98A patent/AU726401B2/en not_active Ceased
- 1997-11-17 AR ARP970105369A patent/AR010615A1/es active IP Right Grant
- 1997-11-17 ID IDP973692A patent/ID18917A/id unknown
- 1997-11-18 US US08/972,783 patent/US5969157A/en not_active Expired - Lifetime
- 1997-11-22 TW TW086117219A patent/TW461888B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HUP9904510A2 (hu) | 2000-05-28 |
SI0842930T1 (en) | 2002-10-31 |
CN1130357C (zh) | 2003-12-10 |
TW461888B (en) | 2001-11-01 |
AU5462298A (en) | 1998-06-10 |
AR010615A1 (es) | 2000-06-28 |
PT842930E (pt) | 2002-08-30 |
ZA9710262B (en) | 1999-05-13 |
DE69712590T2 (de) | 2002-10-31 |
CO4920247A1 (es) | 2000-05-29 |
PE16799A1 (es) | 1999-02-19 |
HUP9904510A3 (en) | 2000-08-28 |
EP0842930B1 (en) | 2002-05-15 |
DE69712590D1 (de) | 2002-06-20 |
US5969157A (en) | 1999-10-19 |
KR20000053333A (ko) | 2000-08-25 |
DK0842930T3 (da) | 2002-07-15 |
EP0842930A1 (en) | 1998-05-20 |
CA2271922A1 (en) | 1998-05-28 |
ES2173399T3 (es) | 2002-10-16 |
JP2001504497A (ja) | 2001-04-03 |
IL129868A (en) | 2002-09-12 |
IL129868A0 (en) | 2000-02-29 |
WO1998022456A1 (en) | 1998-05-28 |
AU726401B2 (en) | 2000-11-09 |
ID18917A (id) | 1998-05-20 |
ATE217620T1 (de) | 2002-06-15 |
CN1237968A (zh) | 1999-12-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A E 9A ANUIDADES. |