DE69736671D1 - Transdermale arzneistoffverabreichungsmatrix zur gleichzeitigen gabe von estradiol und eines weiteren steroids - Google Patents

Transdermale arzneistoffverabreichungsmatrix zur gleichzeitigen gabe von estradiol und eines weiteren steroids

Info

Publication number
DE69736671D1
DE69736671D1 DE69736671T DE69736671T DE69736671D1 DE 69736671 D1 DE69736671 D1 DE 69736671D1 DE 69736671 T DE69736671 T DE 69736671T DE 69736671 T DE69736671 T DE 69736671T DE 69736671 D1 DE69736671 D1 DE 69736671D1
Authority
DE
Germany
Prior art keywords
estradiol
another
steroid
steroids
administrative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69736671T
Other languages
English (en)
Other versions
DE69736671T2 (de
Inventor
Venkateshwaran Srinivasan
D Ebert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Finance LLC
Original Assignee
Watson Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Watson Pharmaceuticals Inc filed Critical Watson Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69736671D1 publication Critical patent/DE69736671D1/de
Publication of DE69736671T2 publication Critical patent/DE69736671T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69736671T 1996-07-19 1997-07-02 Transdermale arzneistoffverabreichungsmatrix zur gleichzeitigen gabe von estradiol und eines weiteren steroids Expired - Lifetime DE69736671T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/683,892 US5783208A (en) 1996-07-19 1996-07-19 Transdermal drug delivery matrix for coadministering estradiol and another steroid
US683892 1996-07-19
PCT/US1997/011673 WO1998003137A1 (en) 1996-07-19 1997-07-02 Transdermal drug delivery matrix for coadministering estradiol and another steroid

Publications (2)

Publication Number Publication Date
DE69736671D1 true DE69736671D1 (de) 2006-10-26
DE69736671T2 DE69736671T2 (de) 2007-09-13

Family

ID=24745888

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69736671T Expired - Lifetime DE69736671T2 (de) 1996-07-19 1997-07-02 Transdermale arzneistoffverabreichungsmatrix zur gleichzeitigen gabe von estradiol und eines weiteren steroids

Country Status (21)

Country Link
US (1) US5783208A (de)
EP (1) EP0921774B1 (de)
JP (2) JP4212115B2 (de)
KR (1) KR100628796B1 (de)
CN (2) CN100536835C (de)
AT (1) ATE339172T1 (de)
AU (1) AU714590B2 (de)
BR (1) BR9710738A (de)
CA (1) CA2259532C (de)
DE (1) DE69736671T2 (de)
DK (1) DK0921774T3 (de)
ES (1) ES2271970T3 (de)
HK (2) HK1020864A1 (de)
HU (1) HUP9904369A3 (de)
IL (1) IL127708A (de)
NO (1) NO325232B1 (de)
NZ (1) NZ333558A (de)
PL (1) PL188009B1 (de)
PT (1) PT921774E (de)
WO (1) WO1998003137A1 (de)
ZA (1) ZA976035B (de)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
NZ311304A (en) * 1995-06-07 1999-03-29 Cygnus Therapeutic Systems Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6624200B2 (en) 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6248358B1 (en) 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
DE19834007C1 (de) * 1998-07-29 2000-02-24 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung
MXPA00006196A (es) * 1998-10-23 2003-07-21 Idea Ag Metodo para desarrollar, evaluar y utilizar asociaciones de macromoleculas y agregados complejos para obtener mejores tasas de asociacion/desasociacion controlable y carga efectiva.
US6984404B1 (en) 1998-11-18 2006-01-10 University Of Florida Research Foundation, Inc. Methods for preparing coated drug particles and pharmaceutical formulations thereof
AU2051600A (en) * 1998-12-10 2000-06-26 Board Of Regents, The University Of Texas System Compositions and methods of modulating cholesterol metabolism
SI1031346T1 (en) 1999-01-27 2002-08-31 Idea Ag Noninvasive vaccination through the skin
SI1031347T1 (en) 1999-01-27 2002-10-31 Idea Ag Transnasal transport/immunisation with highly adaptable carriers
US6297337B1 (en) 1999-05-19 2001-10-02 Pmd Holdings Corp. Bioadhesive polymer compositions
EP1754488A1 (de) 1999-05-24 2007-02-21 Introgen Therapeutics, Inc. Verfahren und Zusammensetzungen für nichtvirale Gentherapie zur Behandlung von hyperproliferativen Krankheiten
US6406745B1 (en) 1999-06-07 2002-06-18 Nanosphere, Inc. Methods for coating particles and particles produced thereby
AU5409699A (en) * 1999-07-05 2001-01-22 Idea Ag A method for the improvement of transport across adaptable semi-permeable barriers
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
WO2001080796A1 (en) * 2000-04-26 2001-11-01 Watson Pharmaceuticals, Inc. Minimizing adverse experience associated with oxybutynin therapy
US7029694B2 (en) 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
US20030124177A1 (en) * 2000-04-26 2003-07-03 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US10293056B1 (en) 2000-05-24 2019-05-21 Board Of Regents, The University Of Texas System Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
CN1541112A (zh) * 2001-08-10 2004-10-27 �ù���ҩ��ʽ���� 经皮吸收制剂
KR20030041596A (ko) * 2001-11-20 2003-05-27 삼일페인트공업 주식회사 의료용 팻치에 적용되는 아크릴 점착제의 제조방법
US7921999B1 (en) * 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
US20040105881A1 (en) * 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
US20070231373A1 (en) * 2004-04-28 2007-10-04 Hunter-Fleming Limited Transdermal Steriod for Formulation
JP2008519784A (ja) * 2004-11-12 2008-06-12 イデア アクチェンゲゼルシャフト 皮膚状態の治療における拡張表面凝集体
US7833979B2 (en) * 2005-04-22 2010-11-16 Amgen Inc. Toxin peptide therapeutic agents
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
US10137135B2 (en) * 2005-08-15 2018-11-27 Allergan Sales, Llc Formulations and methods for providing progestin-only contraception while minimizing adverse side effects associated therewith
PT2450041T (pt) 2005-10-12 2018-11-16 Unimed Pharmaceuticals Llc Gel de testosterona melhorado e método para a sua utilização
WO2007059979A2 (en) * 2005-11-23 2007-05-31 Universität Zürich Allergy treatment by epicutaneous allergen administration
CN101370453B (zh) * 2005-12-14 2013-12-18 努沃研究公司 用于皮肤输送药物的组合物和方法
WO2007092944A2 (en) * 2006-02-08 2007-08-16 Introgen Therapeutics, Inc. Compositions and methods involving gene therapy and proteasome modulation
US8080645B2 (en) 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US9481912B2 (en) 2006-09-12 2016-11-01 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and identifying nucleic acid sequences in biological samples
US8097419B2 (en) 2006-09-12 2012-01-17 Longhorn Vaccines & Diagnostics Llc Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009
US7803769B2 (en) * 2006-10-25 2010-09-28 Amgen Inc. OSK1 peptide analogs and pharmaceutical compositions
WO2008106646A2 (en) * 2007-03-01 2008-09-04 Introgen Therapeutics, Inc Methods and formulations for topical gene therapy
ES2714007T3 (es) 2007-04-09 2019-05-24 Univ Florida Composiciones de vectores rAAV que tienen proteínas de la cápside modificadas en tirosina y métodos para su uso
US8420779B2 (en) * 2007-05-22 2013-04-16 Amgen Inc. Compositions and methods for producing bioactive fusion proteins
US11041215B2 (en) 2007-08-24 2021-06-22 Longhorn Vaccines And Diagnostics, Llc PCR ready compositions and methods for detecting and identifying nucleic acid sequences
US9683256B2 (en) 2007-10-01 2017-06-20 Longhorn Vaccines And Diagnostics, Llc Biological specimen collection and transport system
EP2185196B1 (de) 2007-08-27 2014-06-11 Longhorn Vaccines & Diagnostics, LLC Immunogene zusammensetzungen und verfahren
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
US11041216B2 (en) 2007-10-01 2021-06-22 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples
EP2535428B1 (de) 2007-10-01 2015-09-09 Longhorn Vaccines and Diagnostics, LLC System zum Sammeln und Transportieren biologischer Proben sowie Verfahren zu seiner Verwendung
WO2010135714A2 (en) 2009-05-22 2010-11-25 The Methodist Hospital Research Institute Methods for modulating adipocyte expression using microrna compositions
US8734809B2 (en) 2009-05-28 2014-05-27 University Of Massachusetts AAV's and uses thereof
WO2011133901A2 (en) 2010-04-23 2011-10-27 University Of Massachusetts Aav-based treatment of cholesterol-related disorders
EP3540055A1 (de) 2010-04-23 2019-09-18 University of Massachusetts Auf das zns abzielende aav-vektoren und verfahren zur verwendung davon
NZ602897A (en) 2010-04-23 2014-09-26 Univ Florida Raav-guanylate cyclase compositions and methods for treating leber’s congenital amaurosis-1 (lca1)
BR112013023674A2 (pt) 2011-03-16 2016-12-13 Amgen Inc inibidores potentes e seletivos de nav1.3 e nav1.7
CA2870511C (en) 2011-04-21 2023-08-08 University Of Massachusetts Raav-based compositions and methods for treating alpha-1 anti-trypsin deficiencies
US10149834B2 (en) 2011-12-01 2018-12-11 Teikoku Seiyaku Co., Ltd. Ropinirole-containing adhesive patch
TWI611817B (zh) * 2011-12-01 2018-01-21 帝國製藥股份有限公司 含有羅匹尼羅(ropinirole)之貼附劑
CA3207612A1 (en) 2012-01-26 2013-08-01 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
UY35397A (es) 2013-03-12 2014-10-31 Amgen Inc INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.7
ES2856403T3 (es) 2014-03-18 2021-09-27 Univ Massachusetts Composiciones a base de rAAV y procedimientos para el tratamiento de la esclerosis lateral amiotrofica
US10975391B2 (en) 2014-04-25 2021-04-13 University Of Massachusetts Recombinant AAV vectors useful for reducing immunity against transgene products
EP3200830B1 (de) 2014-10-03 2020-09-09 University of Massachusetts Hocheffiziente bibliotheksidentifizierte aav-vektoren
WO2016065001A1 (en) 2014-10-21 2016-04-28 University Of Massachusetts Recombinant aav variants and uses thereof
CA2967468A1 (en) 2014-12-16 2016-06-23 Board Of Regents Of The University Of Nebraska Gene therapy for juvenile batten disease
EP3294448A4 (de) 2015-05-14 2018-12-12 Longhorn Vaccines and Diagnostics, LLC Schnellverfahren zur extraktion von nukleinsäuren aus biologischen proben
KR20180118105A (ko) 2015-12-04 2018-10-30 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 면역치료를 위한 slc45a2 펩티드
JP6994140B2 (ja) 2016-03-03 2022-02-03 ユニバーシティ オブ マサチューセッツ 非ウイルス的遺伝子導入のための閉鎖型直鎖状二重鎖dna
CN110225975A (zh) 2016-08-23 2019-09-10 阿库斯股份有限公司 用于治疗人受试者中非年龄相关的听力损害的组合物和方法
US10457940B2 (en) 2016-09-22 2019-10-29 University Of Massachusetts AAV treatment of Huntington's disease
CA3040483A1 (en) 2016-10-13 2018-04-19 University Of Massachusetts Aav capsid designs
US11318190B2 (en) 2017-05-05 2022-05-03 United States Government As Represented By The Department Of Veterans Affairs Methods and compositions for treating liver disease
EP3768386A4 (de) 2018-03-23 2022-04-13 University of Massachusetts Gentherapeutika zur behandlung von knochenerkrankungen
EP3784290A4 (de) 2018-04-27 2022-03-23 University of Massachusetts Durch in-vivo-bibliotheksauswahl identifizierte aav-kapside
US20220033824A1 (en) 2018-11-29 2022-02-03 University Of Massachusetts Modulation of sptlc1 via recombinant adeno-associated vectors
EP3927380A1 (de) 2019-02-22 2021-12-29 University of Massachusetts Oxr1-gentherapie
KR20220079857A (ko) 2019-09-13 2022-06-14 루트거스, 더 스테이트 유니버시티 오브 뉴 저지 Aav-상용성 라미닌-링커 중합 단백질
MX2022010050A (es) 2020-02-21 2022-09-05 Akouos Inc Composiciones y metodos para tratar deficiencia auditiva no asociada con la edad en un sujeto humano.
BR112022019304A2 (pt) 2020-03-31 2022-12-06 Univ Massachusetts Variantes de capsídeo de aav e usos das mesmas
WO2021237068A2 (en) 2020-05-21 2021-11-25 Board Of Regents, The University Of Texas System T cell receptors with vgll1 specificity and uses thereof
CN116406305A (zh) 2020-08-17 2023-07-07 麻省理工学院 Shank3基因治疗方法
WO2022120080A1 (en) 2020-12-03 2022-06-09 University Of Massachusetts Development of novel gene therapeutics for fibrodysplasia ossificans progressiva
IL308282A (en) 2021-05-10 2024-01-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Pharmaceutical compositions for the treatment of neurological diseases
KR20240067112A (ko) 2021-09-30 2024-05-16 아카우오스, 인크. Kcnq4-연관 청력손실을 치료하기 위한 조성물 및 방법
WO2023164545A1 (en) 2022-02-23 2023-08-31 Massachusetts Institute Of Technology Methods for upregulating shank3 expression

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954487A (en) * 1979-01-08 1990-09-04 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
IL61721A (en) * 1980-12-16 1984-03-30 Blank Izhak Nitroglycerin preparations
US4537776A (en) * 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
JPS60123417A (ja) * 1983-12-07 1985-07-02 Nitto Electric Ind Co Ltd 薬物投与部材
JPS6160620A (ja) * 1984-09-03 1986-03-28 Teijin Ltd ピログルタミン酸エステル類を含有する医薬品組成物
US5296230A (en) * 1985-02-25 1994-03-22 Rutgers, The State University Of New Jersey Transdermal fertility control system and process
US4762851A (en) * 1985-11-29 1988-08-09 Merck & Co., Inc. Pyroglutamic acid esters used as dermal penetration enhancers for drugs
US5023084A (en) * 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
GB8811408D0 (en) * 1988-05-13 1988-06-15 Unilever Plc Cosmetic composition
EP0364211B1 (de) * 1988-10-11 1994-12-21 Shire Holdings Ltd. Arzneimittelpräparat für perkutane Absorption
US5512292A (en) * 1990-10-29 1996-04-30 Alza Corporation Transdermal contraceptive formulations methods and devices
JPH04342532A (ja) * 1991-05-21 1992-11-30 Sekisui Chem Co Ltd 経皮吸収貼付剤
JP3086288B2 (ja) * 1991-07-23 2000-09-11 扶桑薬品工業株式会社 経皮吸収製剤
JP2948423B2 (ja) * 1992-08-19 1999-09-13 富士写真フイルム株式会社 カリウムイオン分析用イオン選択電極
US5460820B1 (en) * 1993-08-03 1999-08-03 Theratech Inc Method for providing testosterone and optionally estrogen replacement therapy to women
CZ187796A3 (en) * 1993-12-27 1997-01-15 Akzo Nobel Nv Pharmaceutical preparation
FR2717688B1 (fr) * 1994-03-28 1996-07-05 Lhd Lab Hygiene Dietetique Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base d'EVA.
JPH0827003A (ja) * 1994-07-22 1996-01-30 Sekisui Chem Co Ltd 経皮吸収製剤
US5780050A (en) * 1995-07-20 1998-07-14 Theratech, Inc. Drug delivery compositions for improved stability of steroids
DE19629468A1 (de) * 1996-07-11 1998-01-15 Schering Ag Transdermale therapeutische Systeme

Also Published As

Publication number Publication date
ES2271970T3 (es) 2007-04-16
CA2259532A1 (en) 1998-01-29
PT921774E (pt) 2006-12-29
PL188009B1 (pl) 2004-11-30
AU714590B2 (en) 2000-01-06
ZA976035B (en) 1998-06-24
NZ333558A (en) 2000-05-26
DE69736671T2 (de) 2007-09-13
CN1204859C (zh) 2005-06-08
EP0921774A1 (de) 1999-06-16
HUP9904369A2 (hu) 2000-04-28
DK0921774T3 (da) 2007-01-29
PL331239A1 (en) 1999-07-05
KR100628796B1 (ko) 2006-09-27
JP2006342186A (ja) 2006-12-21
BR9710738A (pt) 1999-08-17
CN1636555A (zh) 2005-07-13
CA2259532C (en) 2008-10-07
EP0921774B1 (de) 2006-09-13
NO990179L (no) 1999-01-15
KR20000067934A (ko) 2000-11-25
CN100536835C (zh) 2009-09-09
EP0921774A4 (de) 1999-08-25
HK1078470A1 (en) 2006-03-17
HUP9904369A3 (en) 2000-11-28
NO325232B1 (no) 2008-03-03
NO990179D0 (no) 1999-01-15
CN1225568A (zh) 1999-08-11
JP4212115B2 (ja) 2009-01-21
AU3650397A (en) 1998-02-10
JP2000514695A (ja) 2000-11-07
ATE339172T1 (de) 2006-10-15
HK1020864A1 (en) 2000-05-26
WO1998003137A1 (en) 1998-01-29
IL127708A0 (en) 1999-10-28
US5783208A (en) 1998-07-21
IL127708A (en) 2004-02-19

Similar Documents

Publication Publication Date Title
DE69736671D1 (de) Transdermale arzneistoffverabreichungsmatrix zur gleichzeitigen gabe von estradiol und eines weiteren steroids
DK0781122T3 (da) Matrix til transdermal lægmiddelafgivelse
NZ316026A (en) A transdermal therapeutic system (a hormone patch) in which drugs are contained which are released into the skin comprising a backing film and a pressure sensitive adhesive
DE69426988T2 (de) Transdermale abgabe vorrichtung
KR960702300A (ko) 에스트라디올을 함유하는 경피 치료 시스템 (transdermal therapeutic system containing estradiol)
PT739199E (pt) Adesivo de estradiol com agente reforcador da penetracao
TW336999B (en) Phase retarder and liquid crystal display device using the same
CA2005714A1 (en) Transdermal estrogen/progestin dosage unit, system and process
AU3779399A (en) Drug-containing transdermal patches, plastisols and adhesives
RU98100451A (ru) Трансдермальный пластырь и способ введения 17-деацетилноргестимата отдельно или в сочетании с эстрогеном
DK0655916T3 (da) Middel til transdermal administration indeholdende 3-ketodesogestrel
DK0596903T3 (da) Transdermale, terapeutiske systemer.
ATE293960T1 (de) Transdermale vorrichtung zur verabreichungvon von testosteron
JP2002532540A5 (de)
CA2172265A1 (en) Transdermal delivery device containing an estrogen
ATE289818T1 (de) Transdermales therapeutisches system mit einer östriol enthaltenden bisphosphatekombination

Legal Events

Date Code Title Description
8364 No opposition during term of opposition